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NAME OF DRUG Tablets may be chewed,

swallowedwhole, or crushed
mebendazole and mixed with food.
Generic name: Vermox Administer drug to all family
members,as prescribed, to
Brand name: Vermox Tablet decrease risk of spreading the
infestation.
Classification: anthelmintics
Dietary restrictions, laxatives,
Dosage: Tablets (chewahle): or enemas aren’t necessary.
100 mg
Safe use in children younger
Frequency: Adults and than age 2 hasn't ben
children 2 years of age and established.
older—100 milligrams (mg)
two times a day, morning and
evening, for 3 consecutive
days
Route: OP
INDICATIONS
Pinworm
Roundworm, whipworm, and
hookworm
CONTRAINDICATIONS
Contraindicated in patients
hypersensitive to drug.
MECHANISM OF
ACTION ACTION
Selectively and irreversibly
inhibits uptake of glucose and
other nutrients in susceptible
helminths.
SIDE EFFECTS
CNS: seizures.
GE OCcasional, transient
abdominal painand diarrhea
in massive infestation
andauring expulsion of
worms.
Skin: urticaria.
Other: fever.
Reduced plasma
mebendazole levels,which
may decrease drug's effect.
Monitorpatient closely.
Cimetidine: Increased plasma
mebendaz0le levels. Monitor
patient closely.
NURSING
RESPONSIBILITIES
NAME OF DRUG shouldn't be used in CNS: headache.
patientswitn severe aoric or
milrinone lactate pulmonic valvulardisease in CV: VENTRICULAR
place of surgical correction ARRHYTHMIAS,
Generic name: Primacor ofthe obstruction or during Ventricular ectopic activity,
acute phase of nonsustained ventricular
Brand name: Primacor tachycardia, sustained
MECHANISM OF ventriculartachycardia,
Classification: bipyridines ACTION ventricular fibrillation.
Pregnancy risk category C Prepare I.V. infusion solution NURSING
using halfnormal saline RESPONSIBILITIES
Dosage: injection: 1 mg/ml solution, or D,W. Prepare the
100-mcg/mlsolution by Use cautiously in patients
Injection (premixed): 200 adding 180 ml of diluent per with atrnal futter or
mcg/ml in D,w 20-mg (20-ml) vial, the l50- fibrillation because drug
meg/ml soluon by adding 113 slightlyshortens AV node
Frequency: 50μg/kg ml of diluent per20-mg (20- conduction time and may
administered over a period of ml) vial, and the 200-mcg/ml increase ventricular response
10 minutes usually followed solution by adding 80 ml of rate.
by a continuous infusion at a diluent per 20-mg (20-ml)
dosage titrated between Drug is typically given with
0.375μg/kg/min and Alert: If furosemide or digoxin and diuretics.
0.75μg/kg/min according to torsemide is administered
haemodynamic and clinical imto an l. Iine that contains Improved cardiac output may
response, but should not milinone, a precipitate will increase urine output. Expect
exceed 1.13mg/kg/day total form. dosage reduction in patient's
dose diuretic therapy as heart
Produces inotropic action by failure improves. Potassium
Route: The primary route of InCreasing cellhlar levels of loSS may predispose patient
excretion of milrinone in cAMP Produces vasodilation to digitalis toxicity.
man is via the urine by directly relaxing vascular
smooth muscle. Monitor fluid and electrolyte
INDICATIONS status, blood pressure, heart
Adust-a-dose: For patients rate, and renal function
Short-term treatment of with reral failure, if during therapy. Excessive
heartfailure creatinine clearance is 50 decrease in blood pressure
mL/minute or less, titrate requires discontinuing or
CONTRAINDICATIONS dosage to maximum clinical slowing rate of infusion.
etfect; don t exceed 1.13 Correct hypo-kemia if it
Contraindicated in patients mg/kg/day. occurs during treatment.
hypersensitiveto drug. Drug
SIDE EFFECTS
NAME OF DRUG Frequency:Adults—4000 to to onamides, in fants younger
8000 milligrams (mg) per than plasmosis), in regnant
sulfisoxazole (sulfafurazole, day, divided and given in 4 to women at term, and in breast-
6 doses per day. Children and teeding women.
sulphafurazole) infants 2 months of age and
olde
Generic
name:ERYTHROMYCIN Route: oral MECHANISM OF
ACTIONS
Brand name:Pediazole INDICATIONS
Drug-drug. Methotrexate:
Classification: sulfonamide Urinary tract and systemic May icrease methotrexate
antibiotic infections levels Use together
cautiously.
Dosage: sulfisoxazole Chlamydia trachomatis
(lymphogranulomavenereum Oral anticoagulants:
Tablets: 500 mg Increased anticoagulant
Uncomplicated urethral, effect. Monitor patient for
sulfisoxazole acetyl endocervical bleeding
Liquid: 500 mg/5 ml CONTRAINDICATIONS Oral antidiabetics: Increased
hypoglycemic effect. Monitor
glucose levels
Oral contraceptives: Contraindicated in patients giving first dose. Therapy
Decreased contraceptive hypersensitive age 2 months may begin pending results.
effectiveness and increased (except in congenital toxo-
risk of breakthrough Monitor urine cultures, CBC,
bleeding. Advise patient to PT, INR,and urinalyses
use a before and during therapy.
NURSING
SIDE EFFECTS RESPONSIBILITIES Monitor renal and liver
function testresults.
May increase BUN, Use cautiously in patients
creatinine, amin transferase, with impaired hepatic or Report moderate to severe
and bilirubin levels. renal uncuon, severe allergy diarrhea toprescriber.
or bronchial asthma, and
May increase eosinophil G6PD deficiency Watch for superinfection:
count. May decrease fever or othersigns or
hemoglobin and PT and Obtain specimen for culture symptoms of new infection.
fibrinogen,granulocyte, and sensitivity tests betore
platelet, and WBC Ccounts.
NAME OF DRUG bilirubin, LDH, and GGT
levels.
enoxacin
May increase eosinophil
Generic name: Penetrex count.
Brand name:Penetrex
Classification:quinolone/fluor NURSING
oquinolone antibiotic CONSIDERATIONS
Dosage: Tablets (film- Use cautiously in patients
coated): 200 mg, 400 mg with CNS disorders, such as
severe cerebral
Route: oral arteriosclerosis or seizure
disorders, and in those at
INDICATIONS
Risk for seizures. Drug may
Uncomplicated urinary tract cause CNS stimulation.
infections (UTIs) caused by
susceptible strains of Use cautiously and with
Escherichia coli, dosage adjustments in
Staphylococcus patients with impaired renal
or hepatic function. Monitor
renal function and liver
function tests.
CONTRAINDICATIONS
Obtain specimen for culture
Contraindicated in patients and sensitivity tests before
hypersensitive to drug or giving first dose. Therapy
other fluoroquinolones. may begin pending results.

MECHANISM OF
ACTION
Inhibits bacterial DNA
synthesis, mainly by blocking
DNA gyrase; bactericida.
SIDE EFFECTS
May increase BUN,
creatinine, ALT, AST,
alkaline phosphatase,
NAME OF DRUG impairment, orthostatic
hypotension, and CV disease.
amantadine hydrochloride Monitor renal and liver
functiontests.
Generic name: Symmetrel
Begin treatment within 24 to
Brand name:Gocovri. 48 hoursafter symptoms
appear and continue for24 to
Classification: adamantanes 48 hours after symptoms
disappear (usually 2 to 7 days
Pregnancy risk category C of therapy).

Dosage: Capsules: 100 mg


Syrup: 50 mg/5 ml
Frequency: 200 mg daily may
benefit from an increase up to
300 mg daily in divided
doses.
Route: oral
INDICATIONS
Prophylaxis or symptomatic
treatment of inftuenza type A
virus, respiratory tract
ilinesses
cONTRAINDICATIONS
Contraindicated in patients
hypersensitiveto drug
SIDE EFFECTS
CNS: depression, fatigue,
confusion,dizziness,
hallucinations, anxiety,
irritability, ataxia, insomnia,
headache, light headedness.
CV: peripheral edema,
orthostatic hypotension, heart
failure.
MECHANISM OF
ACTION
Unknown. Possibly inhibits
the uncoating of the infuenza
A virus, preventing release of
infection's viral nucleic acid
intothe host cell.
NURSING
CONSIDERATIONS
Use cautiously in elderly
patients and in
patients with seizure
disorders, heart failure,
peripheral edema, hepatic
disease, mental illness,
eczematoid rash, renal
NAME OF DRUG Oral anticoagulants: Inhibited
vitamin
neomycin sulfate
NURSING
Generic name:Mycifradint, CONSIDERATIONS
Neo-fradin, Neosulft
Brand
name:Bacitracin/neomycin/ Use cautiously in patients
polymyxin b with impairedBrenal
function, neuromuscular
Classification: disorders, or ulcerative bowel
aminoglycoside antibiotics lesions and in elderly
patients. Never administer
Dosage: Oral solution: 125 drug parenterally.
mg/5 ml
Monitor renal function:
Tablets: 500 mg output, specine gravity,
urinalysis, BUN and
Frequency: 4-12 grams creatinine levels, and
of neomycin sulfate per day creatinine clearance. Notiry
(eight to 24 tablets) in
divided doses.  In adjunctive treatment of
hepatic coma, decrease
Route: oral patient's dietary protein and
as-sess neurologic status
INDICATIONS frequently during therapy.
Infectious diarrhea caused
byenteropathogenic
Escherichia coli
CONTRAINDICATIONS
Contraindicated in patients
hypersensitiveto other
aminoglycosides and in
thosewith intestinal
obstruction.
MECHANISM OF
ACTION
Inhibits protein synthesis by
bindingdirectly to the 30S
ribosomal subunit
Generally bactericidal.
SIDE EFFECTS
EENT: ototoxicity.
GI: nausea, vomiting,
diarrhea, malabsorption
syndrome, Clostridium
ditficile-related colitis.
GU: nephrotoxicity, possible
increase in urinary excretion
Digoxin: Decreased digoxin
absorption.
Inereased ototoxicity. Use
together cautiously.
NAME OF DRUG GI: nausea, vomiting,
diarrhea, glossitis, stomatitis,
amoxicillin gastritis, enterocolitis,
trihydrate(amoxycillin abdominal pain,
trihydrate) pseudomembranous colitis,
blackhairy tongue.
Generic name: Alphamoxt
Amoxil, Apo-Amoxit. CONTRAINDICATIONS
Brand name: Contraindicated in patients
Amoxil, Moxatag, hypersensifiveto drug or
and Trimox other penicillins
Classification:penicillin
Dosage: Capsules: 250 mg, NURSING
S00 mg CONSIDERATIONS
Oral suspension: 50 mg/ml Use cautiously in patients
(pediatricdrops), 125 mg/5 with other drug allegies
ml, 250 mg/5 ml (especially to cephalospo
(afterreconstitution) Tins) because of possible
cross-sensitivity and in those
Tablets: 500 mg, 875 mng with mononucleosis
becauseof high risk of
Tablets (chewable): 125 mg, maculopapular rash
250 mg
Obtain specimen for culture
Frequency: every 12 and sensitivity tests before
hours (twice a day) or every giving first dose. Ther-apy
8 hours (three times a day) may begin pending results.
with or without food. The
length of your treatment Before giving, ask patient
depends on the type of about allergicreactions to
infection that you have. penicillin. A negative
historyof penicillin allergy IS
Route: oral no guarantce against allergic
reaction.
INDICATIONS
Systemic infections, acute
andchronic urinary tract
infections causedby
susceptibie strains of gram-
pesitiveand gram-negative
organisms
MECHANISM OF
ACTION
An aminopenicillin that
inhibits cell-wallsynthesis
during bacterial
multiplication.
Bacteria resist amoxicillin by
producingpenicillinases-
enzymes that
hydrolyzeamoxicillin.
SIDE EFFECTS
CNS: lethargy,
hallucinations,
seizures,anxiety, confusion,
agitation, depression,
dizziness, fatigue.

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