Ramos, Louwella Faith M.

2-BN Gynaecology Ward RLE

Pathophysiology of Polycystic ovary syndrome (PCOS)

Modifiable risk factors

-Diet Non Modifiable risk factors
-environmental -genetics
-lifestyle -hormones
-immune system -age

Intrinsic ovarian factors

The body produced more androgen in the

adrenal gland and ovaries.

Excessive androgen disturbed the production of

gonadotropin releasing hormones levels

Excessive gonadotropin releasing hormones levels travels to

the ovaries to the thecal cell and granulosa cell

Signs and
symptoms
This generates disproportion in LH and FSH productions,
increasing LH and decreasing FSH Menstrual
Irregularity

Increase in LH causes increases

Produce big the
but Androgen
non-mature follicles
hormones release and production

Hormonal imbalance signal hypothalamus to

release more hormone to try to correct it.

This create effect called insulin sensitivity

This causes the pancreas to stimulate more

insulin