NAME OOF THE DRUG MECHANISM OF ACTION DOSAGE INDICATION CONTRA- ADVERSE NURSING

INDICATION REACTION CONSIDERATION

*Generic name: *Pharmacokinetics Normal dosage *Adjunctive *Contraindicated CNS: Dizziness, 1 Monitor patient
Hydrochlorothiazide range therapy in in patients vertigo, headache, BP, pulse rate, and
Absorption: 12.5-100 mg/day edema hypersensitive to paresthesia, body weight
*Onset: Diuresis 2hr in 1-2 doses up to associated with drug weakness, frequently. Drug
*Trade name: hypertension 3-4 days 200 mg/day not CHF . cirrhosis, restlessness. may be given with
Hydrodiuril Peak plasma time 1-2.5hr to exceed 50 corticosteroid * Drug may diuretics and beta
Peak effect Diuresis 4-6hr mg/day for and estrogen contain tartrazine CV: orthostatic blockers to
Distribution: hypertension therapy renal and cause allergic hypotension, decrease sodium
Protein Bound 40-68% impairment. reaction, especially allergic retention and
in patient myocarditis, tachycardia and to
Elimination: *Hypertension hypertensive in vasculatis prevent angina
Half-life 5.6-14.8hr as sole therapy aspirin attack.
Excretion: Urine or in GI: pancreatitis,
combination *Contraindicated anorexia, nausea, *Elderly patient
Metabolism and exertion with other in those with CAD epigastric distress, may be more
antihypertensive or mitral valvular vomiting, sensitive to drugs
rheumatic hearth abdominal pain, hypotensive effect
*unlabeled uses disease. diarrhea,
calcium constipation. Alert: Monitor
*Therapeutic Effects nephrolithiasis *Use cautiously in patient closely for
alone or with patient with signs and
amiloride or suspected cardiac symptoms of
allopurinol to disease stroke or lupuslike syndrome
prevent severe renal (sore throat fever
recurrences in impairment and in muscles and joint
hypercalciuric or those taking other aches rash)
normal calciuric antihypertensives.
patient.