BALUNAN, MIKAELLA C.

BSN 4Y2-1 INP COURSE TASK 10

1. Make a drug study on the following Antiviral drugs using the 7column format, give emphasis on the nursing
responsibility.

DRUG MECHANISM OF INDICATION COMMON SIDE NURSING RESPONSIBILITIES

ACTION EFFECTS
Oseltamivir Inhibits the It is used to treat nausea Advise patients to take a
phosphate neuraminidase symptoms caused vomiting missed dose as soon as
(Tamiflu) enzyme, which is by the flu virus  diarrhea remembered. If it is two
expressed on the dizziness hours or less until the next
Classfication: viral surface. The headache dose, skip the missed dose
neuraminidase enzyme promotes nosebleed and continue regular dosing
inhibitors release of virus eye redness or schedule.
from infected discomfort
cells and sleep problems - Ensure patients are aware
facilitates viral (insomnia) of the importance of
movement within continuing their medication,
the respiratory even if they start to feel
tract. better, until they have
completed the course.
 
- Nurses should refer to
manufacturer’s summary of
product characteristics and
to appropriate local
guidelines.

Zanamivir Inhibits influenza It is used to treat headache - It is not recommended for

(Relenza) virus and prevent dizziness treatment
neuraminidase influenza caused nausea or prophylaxis of influenza in
Classification: with the by influenza A vomiting individuals with underlying
neuraminidase possibility of and B viruses. diarrhea airways disease (such
inhibitors alteration of virus cough as asthma or chronic
particle wheezing obstructive pulmonary
aggregation and trouble breathing disease).
release. By ear pain - Serious cases of
binding and cold symptoms bronchospasm, including
inhibiting the such as stuffy fatalities, have been
neuraminidase nose sneezing, reported during treatment
protein, the drug sore throat. with RELENZA in patients
renders the with and without underlying
influenza virus airways disease. Many of
unable to escape these cases were reported
its host cell and during postmarketing and
infect others. causality was difficult to
assess.
- It should be discontinued
in any patient who develops
bronchospasm or decline in
respiratory function;
immediate treatment and
hospitalization may be
required.
Peramivir Peramivir is a Peramivir is Diarrhea - Patient must be
BALUNAN, MIKAELLA C.
BSN 4Y2-1 INP COURSE TASK 10

(Rapivab) cyclopentane indication for the Constipation symptomatic for no more

analogue that treatment of Insomnia than 2 days to receive
competitively acute AST and ALT peramivir.
binds uncomplicated increased - Monitor for signs of
to the active site influenza in High blood neuropsychiatric symptoms
of the influenza patients 18 years pressure (hallucinations, delirium,
virus and older who (hypertension) abnormal behavior) during
neuraminidase. have been therapy.
Peramivir inhibits symptomatic for - Assess patient for skin rash
the no more than 2 during therapy. Monitor
neuraminidase days. closely and treat
activity of strains symptomatically.
of
influenza A and B
viruses
Baloxavir Baloxavir inhibits Baloxavir is diarrhea - Oral: Initiate within 48
marboxil the endonuclease currently bronchitis hours of influenza symptom
(Xofluza) activity of the approved runny or stuffy onset.
polymerase acidic by the FDA for nose - Administer a single
(PA) protein, an treatment of Headache dose with or without food.
influenza virus- acute Nausea - Avoid administration with
specific enzyme in uncomplicated flu dairy products, calcium-
the viral RNA within 2 days of fortified beverages,
polymerase illness onset in polyvalent cation-
complex people 12 years containing laxatives,
required for viral and older who antacids, or oral
gene are supplements (eg, calcium,
transcription, otherwise iron, magnesium, selenium,
resulting in healthy, zinc).
inhibition of or at high risk of
influenza virus developing flu-
replication. related
complications,
and
for post-exposure
prophylaxis of flu
in people 12
years
and older.

2. Give at least 15 Nursing management for a client with Influenza.

1. Achieve normal temperature. Monitor VS especially temperature, every 2-4 hours and as needed

2. Utilize the same methods of temperature reading with each measurement

3. Administer antipyretics as ordered

4. Provide tepid sponge baths

5. Instruct patient/family in use of hypothermia blanket, reasons for use, signs, and symptoms of complications,
etc.
BALUNAN, MIKAELLA C.
BSN 4Y2-1 INP COURSE TASK 10

6. Achieve relief from pain. Administer analgesics as ordered.

7. Provide warm baths or heating pad to aching muscles

8. Encourage gargling with warm water, provide throat lozenges as necessary

9. Instruct patient or in deep breathing, relaxation techniques, guided imagery, massage, and other
nonpharmacologic aids.

10. Educate patient. Use limited amounts of time for teaching, with the provision of a quiet environment

11. Inform patient receiving the vaccine of the possible adverse effects and report them immediately. instruct
patient and/or about influenza types, when typical outbreaks occur, and methods to avoid infection; and instruct
patient and/or about newer antiviral drugs, their effects, when to seek immediate medical attention, and side
effects of medications.

12. Maintain patent airway. Administer oxygen as ordered; monitor oxygen saturation by pulse oximetry, and
notify the physician of readings <90% or as prescribed by the physician

13. Position patient in high Fowler’s or semi-Fowler’s position, if possible

14 Administer bronchodilators as ordered.

15. Perform postural drainage and percussion, as ordered.

16. Encourage fluids, up to 3-4 L/day unless contraindicated and encourage deep breathing exercises and coughing
exercises every 2 hours.

17. Maintain normal breathing pattern. Perform chest physiotherapy, chest percussion, and postural drainage as
ordered

18. Encourage patient to change position every 2 hours and as needed, and assist as needed