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SE M I N A R S I N A R T H R O P L A S T Y 28 (2017) 267–271

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Femoral impaction grafting


Ashton H. Goldman, MD and Rafael J. Sierra, MD*
Department of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905

article info abstra ct

Keywords: Femoral impaction grafting is a utilitarian technique for femoral defects. With modern
Femoral impaction grafting implants, its role may be limited to Paprosky 3B and 4 type femoral deficiencies, especially
Total hip arthroplasty in the younger patient. With appropriate technique, mid- and long-term results have
Paprosky 3B/4 proven this technique to be globally reliable. Periprosthetic fracture is not uncommon with
Femoral reconstruction this technique; however, strategies to mitigate the risk have been developed. A thorough
Cement understanding of the history, technique, results and complications of this technique is
essential for the revision hip surgeon in order to obtain successful results in the most
complex femoral reconstruction cases.
& 2018 Elsevier Inc. All rights reserved.

1. Introduction Progressive impaction occurs over trial implants in order to


recreate a host bone bed in which a stable prosthesis can be
The goals of femoral reconstruction in revision total hip cemented into place. Today, the most common indication is
arthroplasty (THA) are not only to create a durable long-term for the Paprosky 3B femurs in young patients where proximal
reconstruction with a stable implant, but if possible, preserve restoration of bone is desired or if distal fixation is not ideal or
and/or restore bone stock. Different techniques have been used 4 type femurs where there is a lack of proximal bone stock and
to restore bone stock at the time of revision THA. Allograft there is compromise of the isthmus. Other special cases may
prosthetic composites have been shown at midterm to provide also prove this technique to be inviting. Patients with fibrous
adequate fixation and stability. More recently, the use of modern dysplasia of their proximal femurs where distal fixation is
tapered modular stems has been associated with proximal bony compromised may be candidates as well. The newly packed
reconstitution as long as the soft tissues around the proximal cancellous bone can create a new endosteal bed for cementing
implant remain vascular. Finally, the technique of impaction (Fig. 1). Furthermore, an ectatic proximal femur over a well
grafting has been shown to be viable option providing a durable fixed distal cement plug is another scenario consider impac-
reconstruction and preservation of proximal bone stock with tion grafting. This allows the surgeon to perform the recon-
reported both mid-term and long-term excellent results [1–9]. struction without removing the distal cement to get in a longer
Over time, improvements have been made in the technique diaphyseal engaging stem. Other case examples follow similar
which limit complications and improve outcomes. Understand- principles that challenge whether jeopardizing the host bone
ing the indications, technique, and complications will allow a to remove distal diaphyseal blockades to uncemented fixation
surgeon to effectively employ this procedure for some of their is necessary, if a portion of the diaphysis and metaphysis is
most challenging revision cases. appropriate for impaction grafting.

1.1. Indications
2. Technique
The technique of impaction grafting involves the tight packing
of multiple sizes of cancellous bone chips into a closed Templating is important in order to select the correct size
femoral canal or a canal that can be reconstructed and closed. that bypasses the bony deficiency for the planned femoral


Corresponding author.
E-mail address: sierra.rafael@mayo.edu (R.J. Sierra)

https://doi.org/10.1053/j.sart.2018.02.010
1045-4527/& 2018 Elsevier Inc. All rights reserved.
268 SE M I N A R S I N AR T H R O P L A S T Y 28 (2017) 267–271

Figure 1 – A 27 year female with fibrous dysplasia of the proximal femur. (A) Shows preoperative radiographs and previous
hardware. (B) Shows the bone preparation following impaction grafting with an newly created cancellous endosteal
template for the cemented femoral stem. (C) Shows the cemented femoral stem in place. (D) Post operative radiographs
following impaction grafting.
SE M I N A R S I N AR T H R O P L A S T Y 28 (2017) 267–271 269

to the metaphysis around the phantom implant and


impacted with the use of square and half-moon tamps
(Fig. 3D). Once a stable well-impacted tube has been recre-
ated, the bone is dried and pressurized cement fills the canal
followed by a polished, tapered cemented stem. Slow pro-
gressive insertion of stem into the canal as the cement is
polymerizing allows outward directed hoop stresses to fur-
ther impact the graft against the host bone. It is also
important to keep pressurization of the cement during
insertion. A thumb on around the calcar to prevent cement
extrusion is useful. An expedient insertion with cement that
is still in the liquid phase will allow excess cement to expand
out of the top of the metaphysis rather than expand against
the placed graft. Slow insertion of the stem in the correct
version while the cement in the doughy or working phase is
critical for optimal compaction of the graft of the host bone
by the cement.
With modern uncemented implants, it is not uncommon for
stem removal to require the use of an extended trochanteric
osteotomy (ETO). While the ETO facilitates improved acetab-
ular exposure as well as access to the femoral canal, its use
has caused reservation when considering a patient for impac-
tion grafting as some have suggested cement extrusion can
cause non-union of the osteotomy [10,11]. Larger studies have
not shown this to be the case. Charity et al. [12] demonstrated
100% union rate of the ETO by 6 months in 18 cases with an
average of 10 year follow-up. Furthermore, no revisions were
performed for aseptic loosening. Garcia-Rey et al. showed
similar results with 100% healing in 14 cases where an ETO
Figure 2 – (A) Demonstrates the identification of a cortical was employed with use of impaction grafting. With appropri-
defect that must be stabilized with either a plate, strut or ate recreation of the endosteal tube and appropriate impaction
mesh. If the cortex is intact, simply reinforcing with cerclage prior to cementation this concern can be abated.
wires or cables is appropriate. (B) Demonstrates the
placement of the distal cement plug with the creation of an
impacted distal bone plug resting on top of the cement 3. Outcomes
restrictor by using a cannulated impactor.
Outcomes of femoral impaction have been encouraging
world-wide, but its use in the United States continues to be
stem. Following removal of the current stem, removal of limited, likely given the unfamiliarity to the technique. The
fibrous debris is completed in order to maximize the host major advantage of this procedure, while not only creating a
bone contact for graft incorporation. Recreating and stabiliz- reliable and durable construct to restore function, is recre-
ing the diaphysis is then undertaken with struts, plates, or ation of the endosteum. Follow up radiographic and histo-
reinforcement mesh and wires (Fig. 2). The revision technique logic studies have shown that there is reincorporation of the
is reliant on having a physical constraint for the graft and allograft to living bone and this increases with the longevity
must be done without devascularization of the host bone or of the implant [13]. In this study, as early as one month
soft tissues. After placing a distal intramedullary plug, bone postoperatively, woven bone was seen to perculate into the
chips of varying sizes (3–8 mm) are placed in the canal over a impacted graft. Over the next year, increases in osteoid and
guide wire. Typically the smaller the chips are placed more mineralization occurred from the periphery inwards via a
distally. After a small amount of bone is placed in the canal, a fibrous intermediary. By 48 months, the midportion and
cannulated distal impactor is placed over the wire to impact distal aspects of the graft had complete bone reconstitution
the graft in order to create a 2 cm packed cancellous base confirmed with radiographs while the metaphyseal area
below the planned implant (Fig. 3A). Once the diaphysis is demonstrated a mix of new bone and fibrous material [13].
impacted and filled with cancellous graft, the graft is This steady incorporation has led to reliable results low rates
impacted against the diaphysis with the use of progressively of aseptic loosening at mid- and long-term follow up (Table 1)
larger cannulated phantom implants (Fig. 3B). One must take [3–7,9]. The authors recommend the use of fresh frozen
care during this step as it is critical to impact as much bone allograft rather than irradiated bone as there has been some
as possible. With the phantom implant acting as a template, concern with incorporation and remodeling [14]. Table 1
reconstruction of the proximal metaphysis can be under- demonstrates uniformly good results with the technique
taken if necessary with wires and mesh to contain any across several countries. The latest data from the Exeter
uncontained defects (Fig. 3C). Allograft chips are then added group in the United Kingdom reviewed 705 cases over nearly
270 SE M I N A R S I N AR T H R O P L A S T Y 28 (2017) 267–271

Figure 3 – shows the steps of femoral impaction grafting. (A) The distal cement plug with guide wire. Fresh frozen allograft is
impacted with a cannulated tamp. (B) Further impaction of the diaphyseal allograft with cannulated phantom prosthesis. (C)
The phantom prosthesis based off the preoperative template used as a guide for reconstruction of the proximal metaphysis.
(D) Final impaction of the metaphyseal place allograft with a squared tamp. A stem is then cemented into the newly created
intramedullary canal (not shown).

a 30-year period. With an average follow up of nearly 15 implant construct is placed right above a weak ectatic femur
years, femoral aseptic loosening was only 1.2%. With the creating a considerable stress riser. Creation of a stable load
evolution of technique, they were able to see improvement sharing construct in the face of jeopardized bone is critical to
over time. These promising results are not site specific as can prevent this complication. Sierra et al. showed that bypassing
be seen from the study by Stroet et al. They found a 99% the areas of cortical deficiencies or femoral fractures with a
survival for aseptic loosening rate and a femoral survival rate long cemented stem was an effective method to mitigate this
including all cause failure at 95% at an average of 10.6 years risk and other studies confirmed these findings [2,16]. Other
[9]. These more recent, larger studies are consistent with fractures discovered at the time of surgery, whether it be
other studies listed in the table; however, femoral revisions calcar cracks or cortical perforations, need to be treated with
were slightly higher than the aseptic loosening rate due to appropriate principles. Given the likely poor bone quality
infection, periprosthetic fracture, malpositioning, and stem proximally and relatively high prevalence of calcar fractures
breakage [8]. Therefore avoiding these complications is with impaction grafting, prophylactic wiring of the calcar has
essential for long-term survival. been recommended to further decrease this risk [2].
This method of recreating the endosteal femur is highly
demanding technically and requires attention to detail to
4. Complications ensure lasting results as achieved in the aforementioned
studies. Some degree of subsidence (5 mm) can be expected
Periprosthetic fractures, both early and late, are common with in the first 2 years due to the taper slip geometry of the
this technique with reports in the literature between 4% and implant but further subsidence can be related to quality of
10% [1,2,15]. A predisposition for fracture occurs when a stiff the bone graft used and technique. Wraighte and Howard

Table 1 – Favorable Mid- to Long-term Survival Rates of Impaction Grafting Across a Several Countries. Note that all Cause
Survival is Lower Compared to Aseptic Loosening, Which is Related to Periprosthetic Fractures, Infection, etc

Author Country n Follow up (yrs) Loosening Surv (%) All Cause Surv (%)

Ornstein Swedish 1305 8.1 (5–18) 99 94


Lamberton UK 540 6.7 (2–15) 98 84
Garcia-Cimbrelo Spain 81 10.4 (5–17) 99 80
Garvin United States 78 12.8 (12–18.8) 98 93
Wraighte UK 75 10.4 (6.3–14.1) 98 99
te Stroet Netherlands 208 10.6 (4.7–20.9) 99 95
Wilson UK 705 14.7 (9.8–28.3) 98.8 88
SE M I N A R S I N AR T H R O P L A S T Y 28 (2017) 267–271 271

also demonstrated that preoperative bone loss was a predic- refere nces
tor of postoperative subsidence and should be considered
with templating [7]. Taking time to recreate the canal with
fresh frozen cancellous bone chips rather than irradiated [1] Halliday BR, et al. Femoral impaction grafting with cement in
bone or another substitute may improve results [14]. Proper revision total hip replacement. Evolution of the technique
cement technique with appropriate pressurization is critical and results. The Journal of Bone and Joint Surgery. British
Volume 2003;85:809–17.
to create a mantle that will not fracture and lead to pro-
[2] Sierra RJ, et al. The use of long cemented stems for femoral
gressive subsidence.
impaction grafting in revision total hip arthroplasty. The Journal
Stem choice is another variable that may jeopardize results. of Bone and Joint Surgery. American Volume 2008;90:1330–6.
As previously mentioned, using a stem with a tapered-slip [3] Ornstein E, et al. Femoral impaction bone grafting with
geometry rather than a composite beam is important in order the Exeter stem—the Swedish experience: survivorship
not to place all the stress at the distal aspect of the construct analysis of 1305 revisions performed between 1989 and
where it is prone to fracture. A taper-slip helps by providing 2002. The Journal of Bone and Joint Surgery. British Volume
2009;91:441–6.
compressive forces across the entire cement mantle thereby
[4] Lamberton TD, et al. Femoral impaction grafting in revision
further impacting the bone as it gently subsides a few total hip arthroplasty: a follow-up of 540 hips. The Journal of
millimeters in the first few years. Later subsidence of a few Arthroplasty 2011;26:1154–60.
millimeters may also be related to creep within the cement [5] Garcia-Cimbrelo E, Garcia-Rey E, Cruz-Pardos A. The extent
mantle. Attempts to combat early subsidence a polished of the bone defect affects the outcome of femoral recon-
tapered stem in the cement mantle have been unsuccessful. struction in revision surgery with impacted bone grafting: a
Uncemented stems have been shown to have a 50% failure five- to 17-year follow-up study. The Journal of Bone and
Joint Surgery. British Volume 2011;93:1457–64.
rate [17] likely related to the inability to create a continuous
[6] Garvin KL, et al. What is the long-term survival of impaction
equal pressure circumferentially along the entire endosteal allografting of the femur? Clinical Orthopaedics and Related
tube. Similarly beaded cemented implants thought to prevent Research 2013;471:3901–11.
subsidence through increase strength at the implant-cement [7] Wraighte PJ, Howard PW. Femoral impaction bone allograft-
interface have shown to have a high rate of complications ing with an Exeter cemented collarless, polished, tapered
[18]. The current authors recommend the use of stem that is stem in revision hip replacement: a mean follow-up of 10.5
years. The Journal of Bone and Joint Surgery. British Volume
well-established for impaction grafting: a polished tapered
2008;90:1000–4.
stainless steel stem.
[8] Wilson MJ, et al. Femoral impaction bone grafting in revision
hip arthroplasty: 705 cases from the originating centre. The
Bone & Joint Journal 2016;98-B:1611–9.
5. Conclusion [9] te Stroet MA, et al. The outcome of femoral component
revision arthroplasty with impaction allograft bone grafting
Femoral impaction grafting is a reliable technique with appro- and a cemented polished Exeter stem: a prospective cohort
priate stem choice and attention to detail regarding meticulous study of 208 revision arthroplasties with a mean follow-up of
ten years. The Bone & Joint Journal 2015;97-B:771–9.
impaction and cement technique. Recognition of calcar cracks
[10] Hellman EJ, Capello WN, Feinberg JR. Nonunion of extended
and cortical deficiencies must be identified and stabilized in trochanteric osteotomies in impaction grafting femoral revi-
ensure a stable tube to allow allograft incorporation. Subsi- sions. The Journal of Arthroplasty 1998;13:945–9.
dence is not uncommon with this technique and must be [11] Chassin EP, et al. Implant stability in revision total hip arthro-
considered with regards to preoperative planning. With the plasty: allograft bone packing following extended proximal
identification of complications, most notably periprosthetic femoral osteotomy. The Journal of Arthroplasty 1997;12:863–8.
[12] Charity J, et al. Extended trochanteric osteotomy followed by
fractures, an evolution of the technique has lessened the
cemented impaction allografting in revision hip arthroplasty.
burden of this complication. The success of modular conical
The Journal of Arthroplasty 2013;28:154–60.
stems may limit this technique to Paprosky type 4 femurs and [13] Ullmark G, Obrant KJ. Histology of impacted bone-graft
other special cases; however, it is appropriate for a revision incorporation. The Journal of Arthroplasty 2002;17:150–7.
surgeon to consider this as a weapon in their armamentarium [14] Robinson DE, et al. Femoral impaction grafting in revision
when treating a difficult femoral revision. hip arthroplasty with irradiated bone. The Journal of Arthro-
plasty 2002;17:834–40.
[15] Cabanela ME, Trousdale RT, Berry DJ. Impacted cancellous
graft plus cement in hip revision. Clin Orthop Relat Res
6. Disclosures
2003;417:175–82.
[16] Garcia-Rey E, Cruz-Pardos A, Madero R. The evolution of the
Ashton H. Goldman has nothing to disclose. technique of impaction bone grafting in femoral revision
Rafael J. Sierra Royalties from Zimmer Biomet, Link surgery has improved clinical outcome. A prospective mid-
Orthopedics, Board of Directors: MAOA, Muller Foundation, term study. The Journal of Arthroplasty 2015;30:95–100.
Publishing royalties from Springer. [17] Masterson S, Lidder S, Scott G. Impaction femoral allografting
at revision hip arthroplasty: uncemented versus cemented
technique using a Freeman femoral component. The Journal of
Bone and Joint Surgery. British Volume 2012;94:51–5.
7. Acknowledgment [18] Krupp RJ, et al. Impaction grafting for femoral component
revision using a non-polished bead-blasted chrome cobalt
The authors would like to thank Frank Corl for his work on stem-average 8 1/2-year follow-up. The Journal of Arthro-
the illustrations for this paper. plasty 2006;21:1180–6.

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