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ch19

Student: ___________________________________________________________________________

1. Which of the following functions is associated with the blood?

A. delivery of oxygen to tissue cells


B. transport of digestive enzymes to the small intestine
C. maintenance of DNA content of egg cells
D. transport of neurotransmitters across synapses
E. electrical stimulation of the heart
2. A white blood cell engulfing a bacterium is an example of blood functioning in

A. protection.
B. elimination.
C. maintenance.
D. transportation.
E. communication
3. Which type of material is NOT transported by the blood?

A. blood gases
B. nutrients
C. lactic acid
D. neurotransmitters
E. hormones
4. If a blood buffer is absent, what function of the blood would be compromised?

A. maintenance of body temperature


B. regulation of pH
C. clot formaiton
D. transport of ions
E. protection against foreign substances
5. Plasma is ____ while formed elements are ___.

A. a blood gas; blood clots


B. the liquid portion of blood; the cells
C. lacking in protein; regulators of blood osmolality
D. the cellular portion of blood; acellular components
E. mostly protein; the matrix
6. Blood is a type of _________ tissue.

A. epithelial
B. glandular
C. connective
D. areolar
7. The total blood volume is ____ plasma.

A. 50%
B. 90%
C. 75%
D. 55%
8. Which of the following plasma proteins is most abundant?

A. albumin
B. globulins
C. fibrinogen
D. immunoglobulins
E. hemoglobin
9. Plasma

A. is one of the formed elements.


B. is the liquid matrix of the blood.
C. transports waste products but not nutrients.
D. accounts for less than half of the blood volume.
E. is serum plus formed elements.
10. Functions of plasma proteins include

A. body temperature regulation.


B. regulation of osmotic pressure.
C. transportation of oxygen and carbon dioxide.
D. serving as a source of energy for metabolism.
11. The plasma component that forms fibrin, the insoluble protein, in a blood clot is

A. sodium.
B. albumin.
C. globulin.
D. fibrinogen.
E. fibrinolysis.
12. Which of the following is NOT true of plasma?

A. Plasma is about 91% water.


B. Plasma is a colloid.
C. Plasma volume can change drastically.
D. The color of plasma is yellow.
13. Which plasma protein is correctly matched to its function?

A. fibrinogen - transport of fatty acids


B. albumin - helps to fight infection
C. globulin - transport and immunity
D. globulin - blood clotting
14. The only formed elements that possess a nucleus when mature are the

A. thrombocytes.
B. erythrocytes.
C. leukocytes.
D. platelets.
E. RBCs.
15. Hemocytoblast stem cells

A. are specialized cells.


B. are found in yellow bone marrow.
C. form branches of trees.
D. are abundant in the plasma.
E. give rise to all formed elements in the blood.
16. Which of the following is (are) associated with decreased hematopoiesis?

A. hemorrhage
B. vitamin B12 deficiency
C. iron deficiency anemia
D. restricted blood flow to the kidney
E. both vitamin B12 deficiency and iron deficiency anemia
17. Neutrophils of the blood are derived from a population of stem cells called

A. lymphoblasts.
B. proerythroblasts.
C. myeloblasts.
D. megakaryoblasts.
E. monoblasts.
18. Red blood cells will develop from

A. proerythroblasts.
B. monoblasts.
C. myeloblasts.
D. megakaryoblasts.
E. lymphoblasts.
19. Which of the following phrases is least likely to be used in describing erythrocytes?

A. biconcave cells
B. cells can change shape
C. cytoplasm contains hemoglobin
D. nucleus is centrally located
E. main role is transporting blood gases
20. Mature erythrocytes

A. have a centrally located nucleus.


B. are actually just cellular fragments.
C. contain hemoglobin in their cytoplasm.
D. mature from cells called megakaryocytes.
E. do not contain protein.
21. Hemoglobin

A. gives white blood cells their color.


B. transports oxygen in the blood.
C. is normally found in both the plasma and erythrocytes.
D. catalyzes the reaction that forms carbonic acid.
E. is only used once then decomposed.
22. An increase in hemoglobin increases

A. the ability of the blood to carry oxygen to various tissues.


B. the quantity of plasma protein available for blood clotting.
C. the leukocyte count.
D. the body's immune response.
E. the osmotic pressure of the blood.
23. How much oxygen is generally transported in combination with hemoglobin in red blood cells?

A. 1.5%
B. 7%
C. 70%
D. 98.5%
24. Which of the following is NOT a method of carbon dioxide transport in the blood?

A. combined with hemoglobin


B. dissolved in the plasma
C. as bicarbonate ions in the plasma
D. held in the depression of a red blood cell
25. What may be affected if the enzyme carbonic anhydrase was not made in the body?

A. conversion of hemoglobin to oxyhemoglobin


B. conversion of carbon dioxide to bicarbonate ion
C. transport of oxygen by hemoglobin
D. hemolysis of red blood cells
26. Rupture of a red blood cell is called hematopoiesis.

True False
27. Each hemoglobin molecule

A. has one heme group.


B. contains two polypeptide chains.
C. transports four oxygen molecules.
D. has two iron atoms and two globin chains.
E. transports one oxygen molecule.
28. Which of the following is NOT a form of hemoglobin found in the developing human?

A. adult
B. embryonic
C. adolescent
D. fetal
29. The combination of hemoglobin and carbon dioxide is

A. carboxyhemoglobin.
B. oxyhemoglobin.
C. deoxyhemoglobin.
D. carbaminohemoglobin.
30. What gas is also carried by a beta-globin that may help regulate blood pressure?

A. carbon monoxide
B. carbon dioxide
C. nitrogen
D. nitric oxide
31. The oxygenated form of hemoglobin is called

A. oxyhemoglobin.
B. deoxyhemoglobin.
C. carboxyhemoglobin.
D. carbaminohemoglobin.
E. loaded hemoglobin.
32. Iron

A. is needed to produce hemoglobin.


B. is a plasma coagulation factor.
C. is the binding site for carbon dioxide on the hemoglobin molecule.
D. prevents carbon monoxide from binding to hemoglobin.
E. interferes with the normal function of hemoglobin.
33. Which of the following cell types is an immature red blood cell?

A. erythrocyte
B. reticulocyte
C. thrombocyte
D. monocyte
E. leukocyte
34. Erythropoiesis does not require

A. iron.
B. vitamin B12.
C. folate.
D. vitamin K.
E. All of these are required.
35. Which of the following would lead to increased erythropoiesis?

A. increased environmental O2 levels


B. increased erythropoietin levels
C. increased blood pH
D. increased blood pressure
E. increased CO2 levels
36. Mr. Smith moved from a low altitude to a high altitude and experienced an increase in RBCs. Which of the
following caused this increase?

A. the lower temperature present at higher altitudes


B. the lower oxygen concentration seen at higher altitudes
C. the increased metabolic rate seen at higher altitudes
D. the increased CO2 retention that occurs at high altitudes
E. He exercised more.
37. Erythropoietin

A. is a product of the kidney.


B. inhibits the production of erythrocytes.
C. is produced in response to increased blood pressure.
D. is found both in the plasma and inside red blood cells.
E. is produced by the red bone marrow.
38. When defective erythrocytes are broken down,

A. they are removed from the blood by the lungs.


B. bilirubin is formed from the breakdown of hemoglobin.
C. their heme groups are converted into amino acids.
D. their iron is excreted into the small intestine.
E. their components cannot be recycled.
39. When erythrocytes are destroyed, which of the following events occurs?

A. Urine output increases.


B. Iron is secreted into the bile.
C. Heme is transported by transferrin to the liver.
D. The globin portion of the molecule is broken down into amino acids.
E. Bile is manufactured by the gall bladder.
40. Which of the following formed elements do not have chromosomes?

A. erythrocytes
B. reticulocytes
C. erythroblasts
D. erythrocytes and reticulocytes
E. erythrocytes, reticulocytes and erythroblasts
41. Bilirubin

A. is found in white blood cells.


B. may be reused in erythropoiesis.
C. is formed from the globin groups of hemoglobin.
D. is made from bile.
E. may build up in the circulation and cause jaundice.
42. Randolf was suffering from severe hepatitis. His skin appeared to be jaundiced. That color change was due
to

A. increased heme in his circulatory system.


B. increased globin in his circulatory system.
C. increased bilirubin in his circulatory system.
D. decreased rate of globin breakdown.
E. increased globin in his circulatory system, increased bilirubin in his circulatory system and decreased
rate of globin breakdown.
43. In adults, red blood cells are made in one place, spend most of their lifespan in another, and most are finally
destroyed in yet another place. Which choice lists these locations in the correct chronological order?

A. bone marrow; blood vessels; spleen


B. bone marrow; spleen; blood vessels
C. spleen; blood vessels; spleen
D. blood vessels; spleen; bone marrow
E. spleen; blood vessels; bone marrow
44. Which blood component is NOT correctly matched with its function?

A. erythrocytes - transport oxygen


B. leukocytes - protect against disease
C. platelets - phagocytize bacteria
D. plasma proteins - maintain blood osmotic pressure; involved in clotting
E. monocytes - become macrophages
45. On which chromosome is there a mutation that leads to sickle cell anemia?

A. chromosome 3
B. chromosome 11
C. chromosome 14
D. chromosome 21
46. Which of the following is NOT a consequence of sickle-cell anemia?

A. Red blood cells take on the sickle shape when oxygen levels are low.
B. Sickle-shaped red blood cells can become lodged in capillaries.
C. Tissue damage from decreased blood supply.
D. Sickle-shaped red blood cells are less likely to rupture.
47. Which of the following statements regarding leukocytes is TRUE?

A. Leukocytes have no nucleus.


B. Leukocytes play a role in oxygen transport.
C. Leukocytes are the largest of the formed elements.
D. Leukocytes are only fragments of cells.
E. There is only one kind of leukocyte.
48. Which of the following is an agranulocyte?

A. eosinophil
B. basophil
C. neutrophil
D. monocyte
E. erythrocyte
49. The most numerous of the leukocytes is the

A. neutrophil.
B. basophil.
C. eosinophil.
D. lymphocyte.
E. monocyte.
50. Lymphocytes

A. are the largest of the leukocytes.


B. migrate to lymphatic tissue.
C. produce histamine.
D. release heparin.
E. are phagocytic.
51. The ability of white blood cells to leave the circulation and enter tissues is called

A. chemotaxis.
B. diapedesis.
C. margination.
D. intrusion.
E. exocytosis.
52. When a person develops a sore throat, white blood cells are drawn to the area of infection by a process
called

A. chemotaxis.
B. diapedesis.
C. margination.
D. ameboid movement.
E. attraction.
53. A person with an increased eosinophil count might be suffering from

A. an allergic reaction.
B. a viral infection.
C. an acute bacterial infection.
D. a chronic bacterial infection.
E. a head cold.
54. Macrophages are derived from

A. neutrophils.
B. lymphocytes.
C. monocytes.
D. basophils.
E. eosinophils.
55. Which of the following cell types is incorrectly matched with its description?

A. neutrophils - most numerous WBCs


B. basophils - release histamine
C. lymphocytes - become macrophages
D. monocytes - largest of the WBCs
E. eosinophils - attack worm parasites
56. Which white blood cells function primarily as phagocytotic cells?

A. monocytes and lymphocytes


B. basophils and neutrophils
C. eosinophils and monocytes
D. neutrophils and monocytes
57. Platelets

A. are also known as thrombocytes.


B. are actually fragments of cells.
C. play a role in preventing blood loss.
D. can become sticky when exposed to connective tissue
E. All of these choices are correct.
58. Which of the following is a stage of hemostasis?

A. coagulation
B. erythropoiesis
C. platelet formation
D. vascular dilation
E. agglutination
59. During platelet plug formation,

A. platelets stick to the exposed collagen fibers of injured vessels.


B. activated platelets release fibrinogen.
C. thrombin is released from endothelial cells.
D. vitamin K production increases.
E. platelets multiply.
60. The nervous system and certain chemicals can cause the constriction of a blood vessel. This is known as

A. platelet adhesion.
B. vascular spasm.
C. hemostasis.
D. coagulation.
61. In the platelet release reaction,

A. factor XII is activated.


B. ADP and thromboxanes stimulate other platelets to become activated.
C. activated platelets are connected by fibrinogen.
D. prostaglandin production is inhibited.
E. platelets convert to fibrin.
62. What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?

A. thromboxanes
B. von Willebrand factor
C. endothelin
D. fibrinogen
63. Aspirin inhibits platelet plug formation by

A. blocking the binding of platelets to collagen.


B. interfering with the synthesis of prostaglandins.
C. blocking the effects of serotonin.
D. making the platelet surface less sticky.
E. stimulating the release of heparin.
64. When a blood vessel is damaged, which of the following events occurs last?

A. Collagen is exposed.
B. Platelets adhere to collagen.
C. Platelets are activated.
D. Platelets begin to stick to each other and form a plug.
E. von Willebrand factor is produced.
65. A deficiency of which of the following stem cells would result in a marked increase in the clotting time of
blood?

A. lymphoblast
B. megakaryoblast
C. monoblast
D. myeloblast
E. proerythroblast
66. Which of the following events is one of the three main stages of coagulation?

A. conversion of fibrinogen to fibrin


B. platelet aggregation
C. conversion of thrombin to prothrombin
D. platelet plug formation
E. calcium is released
67. In the extrinsic pathway, damaged tissues release

A. activated factor V.
B. calcium.
C. factor VII.
D. thromboplastin (tissue factor III)
E. factor XII.
68. The cascade of events in the intrinsic pathway can be set into motion when _____ comes into contact with
collagen.

A. factor III
B. factor VII
C. factor X
D. factor XII
E. calcium
69. Arrange the following events of coagulation in proper sequence.
(1) prothrombin →thrombin
(2) fibrinogen →fibrin
(3) activation of factor XII
(4) formation of prothrombinase

A. 4, 3, 1, 2
B. 2, 4, 3, 1
C. 3, 4, 1, 2
D. 3, 2, 4, 1
E. 1, 2, 3, 4
70. What ion is necessary for the coagulation process?

A. sodium
B. potassium
C. magnesium
D. calcium
71. Choose the arrangement that lists the chemicals in the order in which they would be used for coagulation.
(1) thrombin
(2) fibrinogen
(3) prothrombinase
(4) activated factor XII

A. 3, 2, 4, 1
B. 4, 3, 2, 1
C. 4, 3, 1, 2
D. 3, 4, 1, 2
E. 3, 1, 4, 2
72. Coumadin (Warfarin)

A. is a potent anticoagulant.
B. is produced by eosinophils.
C. blocks the action of factor X.
D. dissolves blood clots.
E. promotes coagulation.
73. An increased amount of heparin in the blood might

A. speed up the clotting process.


B. slow down the clotting process.
C. stop the clotting process.
D. enhance the clotting process.
E. have no effect on the clotting process.
74. The function of plasmin is to

A. hydrolyze fibrin.
B. activate factor XII.
C. promote platelet plug formation.
D. control osmotic pressure of the blood.
E. promote the formation of plasma.
75. Healing after clot formation involves

A. clot retraction.
B. repair of the damaged blood vessel by connective tissue cells.
C. clot dissolution.
D. serum being squeezed out of the clot.
E. All of these choices are correct.
76. Fibrinolysis is responsible for

A. activation of the intrinsic pathway of coagulation.


B. activation of the extrinsic pathway of coagulation.
C. clot retraction.
D. clot dissolution.
E. clot consolidation.
77. A blood clot attached to a blood vessel wall is called a(an)

A. thrombus.
B. embolus.
C. prostacylin.
D. hemorrhage.
E. anticoagulant.
78. What vitamin is necessary to produce many clotting factors in the liver?

A. vitamin C
B. vitamin K
C. vitamin D
D. vitamin B3
79. When the antigens on erythrocytes bind with antibodies in the plasma,

A. agglutination of erythrocytes occurs.


B. hemolysis of leukocytes may occur.
C. the antibodies dissolve.
D. the blood group changes.
E. coagulation occurs.
80. Agglutination of red blood cells means

A. they rupture.
B. they form a clot.
C. they clump together.
D. they lose their nucleus.
E. they bump into each other.
81. Type AB blood

A. has no antigens on the red cells.


B. has O antigens on the red cells.
C. has both A and B antigens on the red cells.
D. has both A and B antibodies on the red cells.
E. has both A and B antibodies in the plasma.
82. A person with type O blood should receive a blood transfusion from a donor with

A. type A blood.
B. type B blood.
C. type O blood.
D. type AB blood.
E. any type of blood.
83. A person with type B blood

A. has antigen A.
B. has anti-A antibodies .
C. will have a transfusion reaction if given type B blood.
D. has anti-B antibodies.
E. can receive type A blood.
84. When a person is transfused with the wrong blood type,

A. the white cells clot.


B. hemorrhaging occurs.
C. fibrinogen is activated.
D. the erythrocytes agglutinate.
E. they bleed to death.
85. Which blood type is considered the universal recipient?

A. Type A
B. Type B
C. Type AB
D. Type O
86. What type of gene expression occurs when a person has type AB blood?

A. homozygous dominant
B. homozygous recessive
C. incomplete dominance
D. codominance
87. RhoGam injections are given to

A. desensitize the fetus.


B. activate fetal Rh antigens.
C. protect the father.
D. prevent sensitization of the mother.
E. change the mother's blood type.
88. The hematocrit is

A. an estimate of blood flow/hour.


B. the number of WBCs per mm3.
C. the amount of hemoglobin by weight in the blood.
D. the percentage of RBCs in a given volume of blood.
E. the number of RBCs in the body.
89. Why would a person have anti-Rh antibodies present in their blood?

A. They are Rh-positive and were exposed to Rh-negative blood.


B. An Rh-negative woman is carrying an Rh-positive fetus.
C. An Rh-positive woman is carrying an Rh-negative fetus.
D. A person can not have anti-Rh antibodies in their blood.
90. Hemolytic disease of the newborn (HDN) occurs when

A. an Rh-positive woman is carrying an Rh-positive fetus.


B. an Rh-positive woman is carrying an Rh-negative fetus.
C. an Rh-negative woman is carrying an Rh-negative fetus.
D. an Rh-negative woman is carrying an Rh-positive fetus.
91. In which of the following situations might Rh incompatibility develop?

A. Mother is Rh negative; fetus is Rh negative


B. Mother is Rh positive; father is Rh positive
C. Mother is Rh negative; fetus is Rh positive
D. Mother is Rh positive; fetus is Rh negative
E. Mother is Rh positive; fetus is Rh positive
92. In hemolytic disease of the newborn,

A. antibodies from the mother cross the placenta and affect the fetus.
B. hemolysis of white blood cells may occur.
C. fibrin is hydrolyzed.
D. the mother frequently dies during childbirth.
E. antibodies from the fetus cross the placenta and affect the mother.
93. Which of the following is mismatched?

A. blood typing - determines ABO and Rh blood groups of a blood sample


B. blood crossmatch - donor and recipient blood cells are mixed together
C. complete blood count - includes RBC and WBC counts
D. differential count - determines the percent of each kind of leukocyte in the blood
E. hematocrit - percentage of total blood volume composed of RBCs
94. For a person whose hematocrit is 45%, in which choice below are the components of blood correctly
ranked in order of decreasing percent volume?

A. WBCs, plasma, RBCs


B. RBCs, WBCs, plasma
C. plasma, RBCs, WBCs
D. plasma, WBCs, RBCs
E. WBCs, RBCs, plasma
95. The condition characterized by overproduction of erythrocytes is called

A. anemia.
B. leukemia.
C. hemophilia.
D. thalassemia.
E. erythrocytosis.
96. Which of the following is mismatched?

A. aplastic anemia - bone marrow fails to produce erythrocytes


B. hemolytic anemia - increased destruction of erythrocytes
C. pernicious anemia - loss of blood from the body
D. iron deficiency anemia - lack of iron absorption for erythropoiesis
E. hemorrhagic anemia - loss of blood from the body
97. If your son is diagnosed with hemophilia, he would have

A. a disorder of the clotting process.


B. an infection of the blood.
C. an increased erythrocyte count.
D. a type of cancer affecting white blood cells.
E. an antigen-antibody reaction.
98. When large quantities of blood are lost, erythrocytes must be replaced to restore

A. the body's ability to fight infection.


B. oxygen-carrying capacity.
C. thrombin levels.
D. normal blood pH.
E. iron levels.

99. On the diagram of RBC production, what does "A" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
100.On the diagram of RBC production, what does "B" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
101.On the diagram of RBC production, what does "C" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. increased erythropoietin
D. kidney
E. red bone marrow
102.On the diagram of RBC production, what does "D" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
103.On the diagram of RBC production, what does "E" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow

104.These cells are produced by hematopoiesis. What does "A" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
105.These cells are produced by hematopoiesis. What does "B" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
106.These cells are produced by hematopoiesis. What does "C" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
107.These cells are produced by hematopoiesis. What does "D" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
108.These cells are produced by hematopoiesis. What does "E" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell

109.The diagram illustrates platelet plug formation. What does "A" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
110.The diagram illustrates platelet plug formation. What does "B" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
111.The diagram illustrates platelet plug formation. What does "C" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
112.The diagram illustrates platelet plug formation. What does "D" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
113.The diagram illustrates platelet plug formation. What does "E" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Read the two statements and use the following key to choose the best answer.
A. Choose this if the first item is greater than the second item.
B. Choose this if the first item is less than the second item.
C. Choose this if the first item is equal or nearly equal to the second item.
114.(1) the affinity of adult hemoglobin for oxygen
(2) the affinity of fetal hemoglobin for oxygen

________________________________________
115.(1) the rate of erythropoiesis when erythropoietin is present
(2) the rate of erythropoiesis when erythropoietin is absent

________________________________________
116.(1) the number of erythrocytes in a milliliter sample of blood
(2) the number of leukocytes in a milliliter sample of blood

________________________________________
Match the component of blood plasma with the appropriate description.
A. the suspending medium for blood components
B. the most abundant plasma protein
C. a protein that functions in clotting
D. a plasma protein that is involved in immunity
E. involved in osmosis, membrane potentials, and acid-base balance
117.albumin

________________________________________
118.globulin

________________________________________
119.fibrinogen

________________________________________
120.water

________________________________________
121.ions

________________________________________
Match the substance necessary for clotting with its particular role.
A. a mixture of lipoproteins released from injured tissue
B. converts prothrombin to thrombin
C. the insoluble protein that forms the network of the clot
D. needed by the liver to produce prothrombin
E. fibrin-stabilizing factor
122.prothrombinase

________________________________________
123.vitamin K

________________________________________
124.factor XIII

________________________________________
125.fibrin

________________________________________
126.tissue factor

________________________________________
Consider the following chart of laboratory test results of four patients:

127.Which of the patients has anemia?

________________________________________
128.Which of the patients has some type of infection?

________________________________________
129.Which of the patients has polycythemia vera?

________________________________________
130.Which of the patients has thrombocytopenia?

________________________________________
Match the function with the most appropriate category.
A. agglutination
B. coagulation
C. immune function
D. blood Grouping
E. diagnostic Blood Test
131.erythrocytes clumping together

________________________________________
132.monocytes become macrophages

________________________________________
133.determining antigens on RBCs

________________________________________
134.making a differential WBC count

________________________________________
135.process initiated by platelets

________________________________________
136.the last three stages of hemostasis

________________________________________
137.A antigens, B antibodies

________________________________________
138.fibrinogen coverts to fibrin

________________________________________
139.determining blood chemistry

________________________________________
140.exposure to antigens leads to development of antibodies

________________________________________
141.Blood is classified as a type of _______________ tissue.

________________________________________
142.The majority of carbon dioxide is transported in the blood as ______________.

________________________________________
143.When oxygen binds with hemoglobin, the molecule is called ____________.

________________________________________
144.The overproduction of erythrocytes is called ________________.

________________________________________
145.An immature erythrocyte is called a _________________.

________________________________________
146.Low blood oxygen levels stimulate erythrocyte production by increasing the formation of
_________________ by the kidneys.

________________________________________
ch19 Key
1. Which of the following functions is associated with the blood?

A. delivery of oxygen to tissue cells


B. transport of digestive enzymes to the small intestine
C. maintenance of DNA content of egg cells
D. transport of neurotransmitters across synapses
E. electrical stimulation of the heart
Blooms Level: Remember
Section: 19.01
Seeley: 019 Chapter... #2
Topic: Cardiovascular System
VanPutte - Chapter 19 #1

2. A white blood cell engulfing a bacterium is an example of blood functioning in

A. protection.
B. elimination.
C. maintenance.
D. transportation.
E. communication
Blooms Level: Apply
Section: 19.01
Seeley: 019 Chapter... #3
Topic: Cardiovascular System
VanPutte - Chapter 19 #2

3. Which type of material is NOT transported by the blood?

A. blood gases
B. nutrients
C. lactic acid
D. neurotransmitters
E. hormones
Blooms Level: Remember
Section: 19.01
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #3

4. If a blood buffer is absent, what function of the blood would be compromised?

A. maintenance of body temperature


B. regulation of pH
C. clot formaiton
D. transport of ions
E. protection against foreign substances
Blooms Level: Remember
Section: 19.01
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #4
5. Plasma is ____ while formed elements are ___.

A. a blood gas; blood clots


B. the liquid portion of blood; the cells
C. lacking in protein; regulators of blood osmolality
D. the cellular portion of blood; acellular components
E. mostly protein; the matrix
Blooms Level: Remember
Section: 19.02
Seeley: 019 Chapter... #1
Topic: Cardiovascular System
VanPutte - Chapter 19 #5

6. Blood is a type of _________ tissue.

A. epithelial
B. glandular
C. connective
D. areolar
Blooms Level: Remember
Section: 19.02
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #6

7. The total blood volume is ____ plasma.

A. 50%
B. 90%
C. 75%
D. 55%
Blooms Level: Remember
Section: 19.02
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #7

8. Which of the following plasma proteins is most abundant?

A. albumin
B. globulins
C. fibrinogen
D. immunoglobulins
E. hemoglobin
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #5
Topic: Cardiovascular System
VanPutte - Chapter 19 #8
9. Plasma

A. is one of the formed elements.


B. is the liquid matrix of the blood.
C. transports waste products but not nutrients.
D. accounts for less than half of the blood volume.
E. is serum plus formed elements.
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #6
Topic: Cardiovascular System
VanPutte - Chapter 19 #9

10. Functions of plasma proteins include

A. body temperature regulation.


B. regulation of osmotic pressure.
C. transportation of oxygen and carbon dioxide.
D. serving as a source of energy for metabolism.
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #7
Topic: Cardiovascular System
VanPutte - Chapter 19 #10

11. The plasma component that forms fibrin, the insoluble protein, in a blood clot is

A. sodium.
B. albumin.
C. globulin.
D. fibrinogen.
E. fibrinolysis.
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #8
Topic: Cardiovascular System
VanPutte - Chapter 19 #11

12. Which of the following is NOT true of plasma?

A. Plasma is about 91% water.


B. Plasma is a colloid.
C. Plasma volume can change drastically.
D. The color of plasma is yellow.
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #12
13. Which plasma protein is correctly matched to its function?

A. fibrinogen - transport of fatty acids


B. albumin - helps to fight infection
C. globulin - transport and immunity
D. globulin - blood clotting
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #13

14. The only formed elements that possess a nucleus when mature are the

A. thrombocytes.
B. erythrocytes.
C. leukocytes.
D. platelets.
E. RBCs.
Blooms Level: Understand
Section: 19.04
Seeley: 019 Chapter... #12
Topic: Cardiovascular System
VanPutte - Chapter 19 #14

15. Hemocytoblast stem cells

A. are specialized cells.


B. are found in yellow bone marrow.
C. form branches of trees.
D. are abundant in the plasma.
E. give rise to all formed elements in the blood.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #13
Topic: Cardiovascular System
VanPutte - Chapter 19 #15

16. Which of the following is (are) associated with decreased hematopoiesis?

A. hemorrhage
B. vitamin B12 deficiency
C. iron deficiency anemia
D. restricted blood flow to the kidney
E. both vitamin B12 deficiency and iron deficiency anemia
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #14
Topic: Cardiovascular System
VanPutte - Chapter 19 #16
17. Neutrophils of the blood are derived from a population of stem cells called

A. lymphoblasts.
B. proerythroblasts.
C. myeloblasts.
D. megakaryoblasts.
E. monoblasts.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #15
Topic: Cardiovascular System
VanPutte - Chapter 19 #17

18. Red blood cells will develop from

A. proerythroblasts.
B. monoblasts.
C. myeloblasts.
D. megakaryoblasts.
E. lymphoblasts.
Blooms Level: Remember
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #18

19. Which of the following phrases is least likely to be used in describing erythrocytes?

A. biconcave cells
B. cells can change shape
C. cytoplasm contains hemoglobin
D. nucleus is centrally located
E. main role is transporting blood gases
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #16
Topic: Cardiovascular System
VanPutte - Chapter 19 #19

20. Mature erythrocytes

A. have a centrally located nucleus.


B. are actually just cellular fragments.
C. contain hemoglobin in their cytoplasm.
D. mature from cells called megakaryocytes.
E. do not contain protein.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #17
Topic: Cardiovascular System
VanPutte - Chapter 19 #20
21. Hemoglobin

A. gives white blood cells their color.


B. transports oxygen in the blood.
C. is normally found in both the plasma and erythrocytes.
D. catalyzes the reaction that forms carbonic acid.
E. is only used once then decomposed.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #18
Topic: Cardiovascular System
VanPutte - Chapter 19 #21

22. An increase in hemoglobin increases

A. the ability of the blood to carry oxygen to various tissues.


B. the quantity of plasma protein available for blood clotting.
C. the leukocyte count.
D. the body's immune response.
E. the osmotic pressure of the blood.
Blooms Level: Understand
Section: 19.04
Seeley: 019 Chapter... #19
Topic: Cardiovascular System
VanPutte - Chapter 19 #22

23. How much oxygen is generally transported in combination with hemoglobin in red blood cells?

A. 1.5%
B. 7%
C. 70%
D. 98.5%
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #23

24. Which of the following is NOT a method of carbon dioxide transport in the blood?

A. combined with hemoglobin


B. dissolved in the plasma
C. as bicarbonate ions in the plasma
D. held in the depression of a red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #24
25. What may be affected if the enzyme carbonic anhydrase was not made in the body?

A. conversion of hemoglobin to oxyhemoglobin


B. conversion of carbon dioxide to bicarbonate ion
C. transport of oxygen by hemoglobin
D. hemolysis of red blood cells
Blooms Level: Analyze
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #25

26. Rupture of a red blood cell is called hematopoiesis.

FALSE
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #26

27. Each hemoglobin molecule

A. has one heme group.


B. contains two polypeptide chains.
C. transports four oxygen molecules.
D. has two iron atoms and two globin chains.
E. transports one oxygen molecule.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #20
Topic: Cardiovascular System
VanPutte - Chapter 19 #27

28. Which of the following is NOT a form of hemoglobin found in the developing human?

A. adult
B. embryonic
C. adolescent
D. fetal
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #28

29. The combination of hemoglobin and carbon dioxide is

A. carboxyhemoglobin.
B. oxyhemoglobin.
C. deoxyhemoglobin.
D. carbaminohemoglobin.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #29
30. What gas is also carried by a beta-globin that may help regulate blood pressure?

A. carbon monoxide
B. carbon dioxide
C. nitrogen
D. nitric oxide
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #30

31. The oxygenated form of hemoglobin is called

A. oxyhemoglobin.
B. deoxyhemoglobin.
C. carboxyhemoglobin.
D. carbaminohemoglobin.
E. loaded hemoglobin.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #21
Topic: Cardiovascular System
VanPutte - Chapter 19 #31

32. Iron

A. is needed to produce hemoglobin.


B. is a plasma coagulation factor.
C. is the binding site for carbon dioxide on the hemoglobin molecule.
D. prevents carbon monoxide from binding to hemoglobin.
E. interferes with the normal function of hemoglobin.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #22
Topic: Cardiovascular System
VanPutte - Chapter 19 #32

33. Which of the following cell types is an immature red blood cell?

A. erythrocyte
B. reticulocyte
C. thrombocyte
D. monocyte
E. leukocyte
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #25
Topic: Cardiovascular System
VanPutte - Chapter 19 #33
34. Erythropoiesis does not require

A. iron.
B. vitamin B12.
C. folate.
D. vitamin K.
E. All of these are required.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #26
Topic: Cardiovascular System
VanPutte - Chapter 19 #34

35. Which of the following would lead to increased erythropoiesis?

A. increased environmental O2 levels


B. increased erythropoietin levels
C. increased blood pH
D. increased blood pressure
E. increased CO2 levels
Blooms Level: Understand
Section: 19.04
Seeley: 019 Chapter... #27
Topic: Cardiovascular System
VanPutte - Chapter 19 #35

36. Mr. Smith moved from a low altitude to a high altitude and experienced an increase in RBCs. Which of
the following caused this increase?

A. the lower temperature present at higher altitudes


B. the lower oxygen concentration seen at higher altitudes
C. the increased metabolic rate seen at higher altitudes
D. the increased CO2 retention that occurs at high altitudes
E. He exercised more.
Blooms Level: Apply
Section: 19.04
Seeley: 019 Chapter... #28
Topic: Cardiovascular System
VanPutte - Chapter 19 #36

37. Erythropoietin

A. is a product of the kidney.


B. inhibits the production of erythrocytes.
C. is produced in response to increased blood pressure.
D. is found both in the plasma and inside red blood cells.
E. is produced by the red bone marrow.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #29
Topic: Cardiovascular System
VanPutte - Chapter 19 #37
38. When defective erythrocytes are broken down,

A. they are removed from the blood by the lungs.


B. bilirubin is formed from the breakdown of hemoglobin.
C. their heme groups are converted into amino acids.
D. their iron is excreted into the small intestine.
E. their components cannot be recycled.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #30
Topic: Cardiovascular System
VanPutte - Chapter 19 #38

39. When erythrocytes are destroyed, which of the following events occurs?

A. Urine output increases.


B. Iron is secreted into the bile.
C. Heme is transported by transferrin to the liver.
D. The globin portion of the molecule is broken down into amino acids.
E. Bile is manufactured by the gall bladder.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #31
Topic: Cardiovascular System
VanPutte - Chapter 19 #39

40. Which of the following formed elements do not have chromosomes?

A. erythrocytes
B. reticulocytes
C. erythroblasts
D. erythrocytes and reticulocytes
E. erythrocytes, reticulocytes and erythroblasts
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #44
Topic: Cardiovascular System
VanPutte - Chapter 19 #40

41. Bilirubin

A. is found in white blood cells.


B. may be reused in erythropoiesis.
C. is formed from the globin groups of hemoglobin.
D. is made from bile.
E. may build up in the circulation and cause jaundice.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #32
Topic: Cardiovascular System
VanPutte - Chapter 19 #41
42. Randolf was suffering from severe hepatitis. His skin appeared to be jaundiced. That color change was
due to

A. increased heme in his circulatory system.


B. increased globin in his circulatory system.
C. increased bilirubin in his circulatory system.
D. decreased rate of globin breakdown.
E. increased globin in his circulatory system, increased bilirubin in his circulatory system and decreased
rate of globin breakdown.
Blooms Level: Understand
Section: 19.04
Seeley: 019 Chapter... #33
Topic: Cardiovascular System
VanPutte - Chapter 19 #42

43. In adults, red blood cells are made in one place, spend most of their lifespan in another, and most are
finally destroyed in yet another place. Which choice lists these locations in the correct chronological
order?

A. bone marrow; blood vessels; spleen


B. bone marrow; spleen; blood vessels
C. spleen; blood vessels; spleen
D. blood vessels; spleen; bone marrow
E. spleen; blood vessels; bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #34
Topic: Cardiovascular System
VanPutte - Chapter 19 #43

44. Which blood component is NOT correctly matched with its function?

A. erythrocytes - transport oxygen


B. leukocytes - protect against disease
C. platelets - phagocytize bacteria
D. plasma proteins - maintain blood osmotic pressure; involved in clotting
E. monocytes - become macrophages
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #35
Topic: Cardiovascular System
VanPutte - Chapter 19 #44

45. On which chromosome is there a mutation that leads to sickle cell anemia?

A. chromosome 3
B. chromosome 11
C. chromosome 14
D. chromosome 21
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #45
46. Which of the following is NOT a consequence of sickle-cell anemia?

A. Red blood cells take on the sickle shape when oxygen levels are low.
B. Sickle-shaped red blood cells can become lodged in capillaries.
C. Tissue damage from decreased blood supply.
D. Sickle-shaped red blood cells are less likely to rupture.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #46

47. Which of the following statements regarding leukocytes is TRUE?

A. Leukocytes have no nucleus.


B. Leukocytes play a role in oxygen transport.
C. Leukocytes are the largest of the formed elements.
D. Leukocytes are only fragments of cells.
E. There is only one kind of leukocyte.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #36
Topic: Cardiovascular System
VanPutte - Chapter 19 #47

48. Which of the following is an agranulocyte?

A. eosinophil
B. basophil
C. neutrophil
D. monocyte
E. erythrocyte
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #37
Topic: Cardiovascular System
VanPutte - Chapter 19 #48

49. The most numerous of the leukocytes is the

A. neutrophil.
B. basophil.
C. eosinophil.
D. lymphocyte.
E. monocyte.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #38
Topic: Cardiovascular System
VanPutte - Chapter 19 #49
50. Lymphocytes

A. are the largest of the leukocytes.


B. migrate to lymphatic tissue.
C. produce histamine.
D. release heparin.
E. are phagocytic.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #39
Topic: Cardiovascular System
VanPutte - Chapter 19 #50

51. The ability of white blood cells to leave the circulation and enter tissues is called

A. chemotaxis.
B. diapedesis.
C. margination.
D. intrusion.
E. exocytosis.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #40
Topic: Cardiovascular System
VanPutte - Chapter 19 #51

52. When a person develops a sore throat, white blood cells are drawn to the area of infection by a process
called

A. chemotaxis.
B. diapedesis.
C. margination.
D. ameboid movement.
E. attraction.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #41
Topic: Cardiovascular System
VanPutte - Chapter 19 #52

53. A person with an increased eosinophil count might be suffering from

A. an allergic reaction.
B. a viral infection.
C. an acute bacterial infection.
D. a chronic bacterial infection.
E. a head cold.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #42
Topic: Cardiovascular System
VanPutte - Chapter 19 #53
54. Macrophages are derived from

A. neutrophils.
B. lymphocytes.
C. monocytes.
D. basophils.
E. eosinophils.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #43
Topic: Cardiovascular System
VanPutte - Chapter 19 #54

55. Which of the following cell types is incorrectly matched with its description?

A. neutrophils - most numerous WBCs


B. basophils - release histamine
C. lymphocytes - become macrophages
D. monocytes - largest of the WBCs
E. eosinophils - attack worm parasites
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #45
Topic: Cardiovascular System
VanPutte - Chapter 19 #55

56. Which white blood cells function primarily as phagocytotic cells?

A. monocytes and lymphocytes


B. basophils and neutrophils
C. eosinophils and monocytes
D. neutrophils and monocytes
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #56

57. Platelets

A. are also known as thrombocytes.


B. are actually fragments of cells.
C. play a role in preventing blood loss.
D. can become sticky when exposed to connective tissue
E. All of these choices are correct.
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #46
Topic: Cardiovascular System
VanPutte - Chapter 19 #57
58. Which of the following is a stage of hemostasis?

A. coagulation
B. erythropoiesis
C. platelet formation
D. vascular dilation
E. agglutination
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #48
Topic: Cardiovascular System
VanPutte - Chapter 19 #58

59. During platelet plug formation,

A. platelets stick to the exposed collagen fibers of injured vessels.


B. activated platelets release fibrinogen.
C. thrombin is released from endothelial cells.
D. vitamin K production increases.
E. platelets multiply.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #49
Topic: Cardiovascular System
VanPutte - Chapter 19 #59

60. The nervous system and certain chemicals can cause the constriction of a blood vessel. This is known as

A. platelet adhesion.
B. vascular spasm.
C. hemostasis.
D. coagulation.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #60

61. In the platelet release reaction,

A. factor XII is activated.


B. ADP and thromboxanes stimulate other platelets to become activated.
C. activated platelets are connected by fibrinogen.
D. prostaglandin production is inhibited.
E. platelets convert to fibrin.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #50
Topic: Cardiovascular System
VanPutte - Chapter 19 #61
62. What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?

A. thromboxanes
B. von Willebrand factor
C. endothelin
D. fibrinogen
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #62

63. Aspirin inhibits platelet plug formation by

A. blocking the binding of platelets to collagen.


B. interfering with the synthesis of prostaglandins.
C. blocking the effects of serotonin.
D. making the platelet surface less sticky.
E. stimulating the release of heparin.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #51
Topic: Cardiovascular System
VanPutte - Chapter 19 #63

64. When a blood vessel is damaged, which of the following events occurs last?

A. Collagen is exposed.
B. Platelets adhere to collagen.
C. Platelets are activated.
D. Platelets begin to stick to each other and form a plug.
E. von Willebrand factor is produced.
Blooms Level: Understand
Section: 19.05
Seeley: 019 Chapter... #52
Topic: Cardiovascular System
VanPutte - Chapter 19 #64

65. A deficiency of which of the following stem cells would result in a marked increase in the clotting time
of blood?

A. lymphoblast
B. megakaryoblast
C. monoblast
D. myeloblast
E. proerythroblast
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #53
Topic: Cardiovascular System
VanPutte - Chapter 19 #65
66. Which of the following events is one of the three main stages of coagulation?

A. conversion of fibrinogen to fibrin


B. platelet aggregation
C. conversion of thrombin to prothrombin
D. platelet plug formation
E. calcium is released
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #54
Topic: Cardiovascular System
VanPutte - Chapter 19 #66

67. In the extrinsic pathway, damaged tissues release

A. activated factor V.
B. calcium.
C. factor VII.
D. thromboplastin (tissue factor III)
E. factor XII.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #55
Topic: Cardiovascular System
VanPutte - Chapter 19 #67

68. The cascade of events in the intrinsic pathway can be set into motion when _____ comes into contact
with collagen.

A. factor III
B. factor VII
C. factor X
D. factor XII
E. calcium
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #56
Topic: Cardiovascular System
VanPutte - Chapter 19 #68

69. Arrange the following events of coagulation in proper sequence.


(1) prothrombin →thrombin
(2) fibrinogen →fibrin
(3) activation of factor XII
(4) formation of prothrombinase

A. 4, 3, 1, 2
B. 2, 4, 3, 1
C. 3, 4, 1, 2
D. 3, 2, 4, 1
E. 1, 2, 3, 4
Blooms Level: Understand
Section: 19.05
Seeley: 019 Chapter... #57
Topic: Cardiovascular System
VanPutte - Chapter 19 #69
70. What ion is necessary for the coagulation process?

A. sodium
B. potassium
C. magnesium
D. calcium
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #70

71. Choose the arrangement that lists the chemicals in the order in which they would be used for
coagulation.
(1) thrombin
(2) fibrinogen
(3) prothrombinase
(4) activated factor XII

A. 3, 2, 4, 1
B. 4, 3, 2, 1
C. 4, 3, 1, 2
D. 3, 4, 1, 2
E. 3, 1, 4, 2
Blooms Level: Understand
Section: 19.05
Seeley: 019 Chapter... #58
Topic: Cardiovascular System
VanPutte - Chapter 19 #71

72. Coumadin (Warfarin)

A. is a potent anticoagulant.
B. is produced by eosinophils.
C. blocks the action of factor X.
D. dissolves blood clots.
E. promotes coagulation.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #59
Topic: Cardiovascular System
VanPutte - Chapter 19 #72

73. An increased amount of heparin in the blood might

A. speed up the clotting process.


B. slow down the clotting process.
C. stop the clotting process.
D. enhance the clotting process.
E. have no effect on the clotting process.
Blooms Level: Understand
Section: 19.05
Seeley: 019 Chapter... #60
Topic: Cardiovascular System
VanPutte - Chapter 19 #73
74. The function of plasmin is to

A. hydrolyze fibrin.
B. activate factor XII.
C. promote platelet plug formation.
D. control osmotic pressure of the blood.
E. promote the formation of plasma.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #61
Topic: Cardiovascular System
VanPutte - Chapter 19 #74

75. Healing after clot formation involves

A. clot retraction.
B. repair of the damaged blood vessel by connective tissue cells.
C. clot dissolution.
D. serum being squeezed out of the clot.
E. All of these choices are correct.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #62
Topic: Cardiovascular System
VanPutte - Chapter 19 #75

76. Fibrinolysis is responsible for

A. activation of the intrinsic pathway of coagulation.


B. activation of the extrinsic pathway of coagulation.
C. clot retraction.
D. clot dissolution.
E. clot consolidation.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #63
Topic: Cardiovascular System
VanPutte - Chapter 19 #76

77. A blood clot attached to a blood vessel wall is called a(an)

A. thrombus.
B. embolus.
C. prostacylin.
D. hemorrhage.
E. anticoagulant.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #64
Topic: Cardiovascular System
VanPutte - Chapter 19 #77
78. What vitamin is necessary to produce many clotting factors in the liver?

A. vitamin C
B. vitamin K
C. vitamin D
D. vitamin B3
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #78

79. When the antigens on erythrocytes bind with antibodies in the plasma,

A. agglutination of erythrocytes occurs.


B. hemolysis of leukocytes may occur.
C. the antibodies dissolve.
D. the blood group changes.
E. coagulation occurs.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #66
Topic: Cardiovascular System
VanPutte - Chapter 19 #79

80. Agglutination of red blood cells means

A. they rupture.
B. they form a clot.
C. they clump together.
D. they lose their nucleus.
E. they bump into each other.
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #67
Topic: Cardiovascular System
VanPutte - Chapter 19 #80

81. Type AB blood

A. has no antigens on the red cells.


B. has O antigens on the red cells.
C. has both A and B antigens on the red cells.
D. has both A and B antibodies on the red cells.
E. has both A and B antibodies in the plasma.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #68
Topic: Cardiovascular System
VanPutte - Chapter 19 #81
82. A person with type O blood should receive a blood transfusion from a donor with

A. type A blood.
B. type B blood.
C. type O blood.
D. type AB blood.
E. any type of blood.
Blooms Level: Understand
Section: 19.06
Seeley: 019 Chapter... #69
Topic: Cardiovascular System
VanPutte - Chapter 19 #82

83. A person with type B blood

A. has antigen A.
B. has anti-A antibodies .
C. will have a transfusion reaction if given type B blood.
D. has anti-B antibodies.
E. can receive type A blood.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #70
Topic: Cardiovascular System
VanPutte - Chapter 19 #83

84. When a person is transfused with the wrong blood type,

A. the white cells clot.


B. hemorrhaging occurs.
C. fibrinogen is activated.
D. the erythrocytes agglutinate.
E. they bleed to death.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #71
Topic: Cardiovascular System
VanPutte - Chapter 19 #84

85. Which blood type is considered the universal recipient?

A. Type A
B. Type B
C. Type AB
D. Type O
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #85
86. What type of gene expression occurs when a person has type AB blood?

A. homozygous dominant
B. homozygous recessive
C. incomplete dominance
D. codominance
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #86

87. RhoGam injections are given to

A. desensitize the fetus.


B. activate fetal Rh antigens.
C. protect the father.
D. prevent sensitization of the mother.
E. change the mother's blood type.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #72
Topic: Cardiovascular System
VanPutte - Chapter 19 #87

88. The hematocrit is

A. an estimate of blood flow/hour.


B. the number of WBCs per mm3.
C. the amount of hemoglobin by weight in the blood.
D. the percentage of RBCs in a given volume of blood.
E. the number of RBCs in the body.
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #73
Topic: Cardiovascular System
VanPutte - Chapter 19 #88

89. Why would a person have anti-Rh antibodies present in their blood?

A. They are Rh-positive and were exposed to Rh-negative blood.


B. An Rh-negative woman is carrying an Rh-positive fetus.
C. An Rh-positive woman is carrying an Rh-negative fetus.
D. A person can not have anti-Rh antibodies in their blood.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #89
90. Hemolytic disease of the newborn (HDN) occurs when

A. an Rh-positive woman is carrying an Rh-positive fetus.


B. an Rh-positive woman is carrying an Rh-negative fetus.
C. an Rh-negative woman is carrying an Rh-negative fetus.
D. an Rh-negative woman is carrying an Rh-positive fetus.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter...
Topic: Cardiovascular System
VanPutte - Chapter 19 #90

91. In which of the following situations might Rh incompatibility develop?

A. Mother is Rh negative; fetus is Rh negative


B. Mother is Rh positive; father is Rh positive
C. Mother is Rh negative; fetus is Rh positive
D. Mother is Rh positive; fetus is Rh negative
E. Mother is Rh positive; fetus is Rh positive
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #74
Topic: Cardiovascular System
VanPutte - Chapter 19 #91

92. In hemolytic disease of the newborn,

A. antibodies from the mother cross the placenta and affect the fetus.
B. hemolysis of white blood cells may occur.
C. fibrin is hydrolyzed.
D. the mother frequently dies during childbirth.
E. antibodies from the fetus cross the placenta and affect the mother.
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #75
Topic: Cardiovascular System
VanPutte - Chapter 19 #92

93. Which of the following is mismatched?

A. blood typing - determines ABO and Rh blood groups of a blood sample


B. blood crossmatch - donor and recipient blood cells are mixed together
C. complete blood count - includes RBC and WBC counts
D. differential count - determines the percent of each kind of leukocyte in the blood
E. hematocrit - percentage of total blood volume composed of RBCs
Blooms Level: Understand
Section: 19.07
Seeley: 019 Chapter... #76
Topic: Cardiovascular System
VanPutte - Chapter 19 #93
94. For a person whose hematocrit is 45%, in which choice below are the components of blood correctly
ranked in order of decreasing percent volume?

A. WBCs, plasma, RBCs


B. RBCs, WBCs, plasma
C. plasma, RBCs, WBCs
D. plasma, WBCs, RBCs
E. WBCs, RBCs, plasma
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #11
Topic: Cardiovascular System
VanPutte - Chapter 19 #94

95. The condition characterized by overproduction of erythrocytes is called

A. anemia.
B. leukemia.
C. hemophilia.
D. thalassemia.
E. erythrocytosis.
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #23
Topic: Cardiovascular System
VanPutte - Chapter 19 #95

96. Which of the following is mismatched?

A. aplastic anemia - bone marrow fails to produce erythrocytes


B. hemolytic anemia - increased destruction of erythrocytes
C. pernicious anemia - loss of blood from the body
D. iron deficiency anemia - lack of iron absorption for erythropoiesis
E. hemorrhagic anemia - loss of blood from the body
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #24
Topic: Cardiovascular System
VanPutte - Chapter 19 #96

97. If your son is diagnosed with hemophilia, he would have

A. a disorder of the clotting process.


B. an infection of the blood.
C. an increased erythrocyte count.
D. a type of cancer affecting white blood cells.
E. an antigen-antibody reaction.
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #47
Topic: Cardiovascular System
VanPutte - Chapter 19 #97
98. When large quantities of blood are lost, erythrocytes must be replaced to restore

A. the body's ability to fight infection.


B. oxygen-carrying capacity.
C. thrombin levels.
D. normal blood pH.
E. iron levels.
Blooms Level: Apply
Section: 19.07
Seeley: 019 Chapter... #65
Topic: Cardiovascular System
VanPutte - Chapter 19 #98

VanPutte - Chapter 19

99. On the diagram of RBC production, what does "A" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #77
Topic: Cardiovascular System
VanPutte - Chapter 19 #99

100. On the diagram of RBC production, what does "B" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #78
Topic: Cardiovascular System
VanPutte - Chapter 19 #100
101. On the diagram of RBC production, what does "C" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. increased erythropoietin
D. kidney
E. red bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #79
Topic: Cardiovascular System
VanPutte - Chapter 19 #101

102. On the diagram of RBC production, what does "D" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #80
Topic: Cardiovascular System
VanPutte - Chapter 19 #102

103. On the diagram of RBC production, what does "E" represent?

A. increased blood oxygen


B. decreased blood oxygen
C. erythropoietin
D. kidney
E. red bone marrow
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #81
Topic: Cardiovascular System
VanPutte - Chapter 19 #103

VanPutte - Chapter 19
104. These cells are produced by hematopoiesis. What does "A" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #82
Topic: Cardiovascular System
VanPutte - Chapter 19 #104

105. These cells are produced by hematopoiesis. What does "B" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #83
Topic: Cardiovascular System
VanPutte - Chapter 19 #105

106. These cells are produced by hematopoiesis. What does "C" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #84
Topic: Cardiovascular System
VanPutte - Chapter 19 #106

107. These cells are produced by hematopoiesis. What does "D" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #85
Topic: Cardiovascular System
VanPutte - Chapter 19 #107
108. These cells are produced by hematopoiesis. What does "E" represent?

A. granulocytes
B. platelets
C. lymphocyte
D. neutrophil
E. red blood cell
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #86
Topic: Cardiovascular System
VanPutte - Chapter 19 #108

VanPutte - Chapter 19

109. The diagram illustrates platelet plug formation. What does "A" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #87
Topic: Cardiovascular System
VanPutte - Chapter 19 #109

110. The diagram illustrates platelet plug formation. What does "B" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #88
Topic: Cardiovascular System
VanPutte - Chapter 19 #110
111. The diagram illustrates platelet plug formation. What does "C" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #89
Topic: Cardiovascular System
VanPutte - Chapter 19 #111

112. The diagram illustrates platelet plug formation. What does "D" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #90
Topic: Cardiovascular System
VanPutte - Chapter 19 #112

113. The diagram illustrates platelet plug formation. What does "E" represent?

A. fibrinogen receptor
B. fibrinogen
C. platelet
D. ADP
E. von Willebrand factor
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #91
Topic: Cardiovascular System
VanPutte - Chapter 19 #113

Read the two statements and use the following key to choose the best answer.
A. Choose this if the first item is greater than the second item.
B. Choose this if the first item is less than the second item.
C. Choose this if the first item is equal or nearly equal to the second item.
VanPutte - Chapter 19

114. (1) the affinity of adult hemoglobin for oxygen


(2) the affinity of fetal hemoglobin for oxygen

B
Blooms Level: Analyze
Section: 19.04
Seeley: 019 Chapter... #92
Topic: Cardiovascular System
VanPutte - Chapter 19 #114
115. (1) the rate of erythropoiesis when erythropoietin is present
(2) the rate of erythropoiesis when erythropoietin is absent

A
Blooms Level: Analyze
Section: 19.04
Seeley: 019 Chapter... #93
Topic: Cardiovascular System
VanPutte - Chapter 19 #115

116. (1) the number of erythrocytes in a milliliter sample of blood


(2) the number of leukocytes in a milliliter sample of blood

A
Blooms Level: Analyze
Section: 19.04
Seeley: 019 Chapter... #94
Topic: Cardiovascular System
VanPutte - Chapter 19 #116

Match the component of blood plasma with the appropriate description.


A. the suspending medium for blood components
B. the most abundant plasma protein
C. a protein that functions in clotting
D. a plasma protein that is involved in immunity
E. involved in osmosis, membrane potentials, and acid-base balance
VanPutte - Chapter 19

117. albumin

B
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #95
Topic: Cardiovascular System
VanPutte - Chapter 19 #117

118. globulin

D
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #96
Topic: Cardiovascular System
VanPutte - Chapter 19 #118

119. fibrinogen

C
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #97
Topic: Cardiovascular System
VanPutte - Chapter 19 #119
120. water

A
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #98
Topic: Cardiovascular System
VanPutte - Chapter 19 #120

121. ions

E
Blooms Level: Remember
Section: 19.03
Seeley: 019 Chapter... #99
Topic: Cardiovascular System
VanPutte - Chapter 19 #121

Match the substance necessary for clotting with its particular role.
A. a mixture of lipoproteins released from injured tissue
B. converts prothrombin to thrombin
C. the insoluble protein that forms the network of the clot
D. needed by the liver to produce prothrombin
E. fibrin-stabilizing factor
VanPutte - Chapter 19

122. prothrombinase

B
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #100
Topic: Cardiovascular System
VanPutte - Chapter 19 #122

123. vitamin K

D
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #101
Topic: Cardiovascular System
VanPutte - Chapter 19 #123

124. factor XIII

E
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #102
Topic: Cardiovascular System
VanPutte - Chapter 19 #124
125. fibrin

C
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #103
Topic: Cardiovascular System
VanPutte - Chapter 19 #125

126. tissue factor

A
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #104
Topic: Cardiovascular System
VanPutte - Chapter 19 #126

Consider the following chart of laboratory test results of four patients:

VanPutte - Chapter 19

127. Which of the patients has anemia?

Patient C
Blooms Level: Evaluate
Section: 19.07
Seeley: 019 Chapter... #105
Topic: Cardiovascular System
VanPutte - Chapter 19 #127

128. Which of the patients has some type of infection?

Patient D
Blooms Level: Evaluate
Section: 19.07
Seeley: 019 Chapter... #106
Topic: Cardiovascular System
VanPutte - Chapter 19 #128

129. Which of the patients has polycythemia vera?

Patient A
Blooms Level: Evaluate
Section: 19.07
Seeley: 019 Chapter... #107
Topic: Cardiovascular System
VanPutte - Chapter 19 #129
130. Which of the patients has thrombocytopenia?

Patient B
Blooms Level: Evaluate
Section: 19.07
Seeley: 019 Chapter... #108
Topic: Cardiovascular System
VanPutte - Chapter 19 #130

Match the function with the most appropriate category.


A. agglutination
B. coagulation
C. immune function
D. blood Grouping
E. diagnostic Blood Test
VanPutte - Chapter 19

131. erythrocytes clumping together

A
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #109
Topic: Cardiovascular System
VanPutte - Chapter 19 #131

132. monocytes become macrophages

C
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #110
Topic: Cardiovascular System
VanPutte - Chapter 19 #132

133. determining antigens on RBCs

D
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #111
Topic: Cardiovascular System
VanPutte - Chapter 19 #133

134. making a differential WBC count

E
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #112
Topic: Cardiovascular System
VanPutte - Chapter 19 #134
135. process initiated by platelets

B
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #113
Topic: Cardiovascular System
VanPutte - Chapter 19 #135

136. the last three stages of hemostasis

B
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #114
Topic: Cardiovascular System
VanPutte - Chapter 19 #136

137. A antigens, B antibodies

D
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #115
Topic: Cardiovascular System
VanPutte - Chapter 19 #137

138. fibrinogen coverts to fibrin

B
Blooms Level: Remember
Section: 19.05
Seeley: 019 Chapter... #116
Topic: Cardiovascular System
VanPutte - Chapter 19 #138

139. determining blood chemistry

E
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #117
Topic: Cardiovascular System
VanPutte - Chapter 19 #139

140. exposure to antigens leads to development of antibodies

C
Blooms Level: Remember
Section: 19.06
Seeley: 019 Chapter... #118
Topic: Cardiovascular System
VanPutte - Chapter 19 #140
141. Blood is classified as a type of _______________ tissue.

connective
Blooms Level: Remember
Section: 19.02
Seeley: 019 Chapter... #119
Topic: Cardiovascular System
VanPutte - Chapter 19 #141

142. The majority of carbon dioxide is transported in the blood as ______________.

bicarbonate ions
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #120
Topic: Cardiovascular System
VanPutte - Chapter 19 #142

143. When oxygen binds with hemoglobin, the molecule is called ____________.

oxyhemoglobin
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #121
Topic: Cardiovascular System
VanPutte - Chapter 19 #143

144. The overproduction of erythrocytes is called ________________.

erythrocytosis
Blooms Level: Remember
Section: 19.07
Seeley: 019 Chapter... #122
Topic: Cardiovascular System
VanPutte - Chapter 19 #144

145. An immature erythrocyte is called a _________________.

reticulocyte
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #123
Topic: Cardiovascular System
VanPutte - Chapter 19 #145

146. Low blood oxygen levels stimulate erythrocyte production by increasing the formation of
_________________ by the kidneys.

erythropoietin
Blooms Level: Remember
Section: 19.04
Seeley: 019 Chapter... #124
Topic: Cardiovascular System
VanPutte - Chapter 19 #146
ch19 Summary
Category # of
Questions
Blooms Level: Analyze 4
Blooms Level: Apply 3
Blooms Level: Evaluate 4
Blooms Level: Remember 125
Blooms Level: Understand 10
Section: 19.01 4
Section: 19.02 4
Section: 19.03 11
Section: 19.04 61
Section: 19.05 36
Section: 19.06 15
Section: 19.07 14
Seeley: 019 Chapter... 25
Seeley: 019 Chapter... #1 1
Seeley: 019 Chapter... #100 1
Seeley: 019 Chapter... #101 1
Seeley: 019 Chapter... #102 1
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Topic: Cardiovascular System 146
VanPutte - Chapter 19 154

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