Davis, J. (2018). Clitoria ternatea benefits and side effects.

Retrieved from
https://bodynutrition.org/clitoria-ternatea/

According to Davis (2018) Clitoria Ternatea has benefits and side effects. Clitoria has compounds that
have beneficial effects to a person’s body. It has bioactive compounds, tannins, saponins, triterpenoids,
phenols, flavonoids, alkaloids and cardiac glycosides that makes it herb beneficial. It is stated in the
article that there are 5 benefits of clitoria ternatea. First, clitoria ternatea can boost memory in animal
studies. Learning and memory of rats were enhance when the extract of ternatea was administered
orally in the rats. Second, clitoria may help treat anxiety disorders. In a research conducted in 2012,
clitoria was used to a therapy and it provides improvement in the therapy. Third, clitoria ternatea has a
potential to be an effective treatment for depression. In one study, researchers were able to extract
different compounds from clitoria and one caught their attention, the linolenic acid and palmitic acid
that are good for aiding depression. Fourth, clitoria has antioxidant properties. In a study conducted on
2013, clitoria has the strongest potential of being a source of antioxidants. Lastly, clitoria ternatea may
be an effective wound healer. It was found out that its seeds and root extracts has improve wound
healing. It is found out that the seed extract contains flavonol glycosides is the compound that is
responsible for healing the wound.

Mukherjee, P, et al. (2008). The Ayurvedic medicine Clitoria

ternatea-From traditional use to scientific assessment. Retrieved from
https://www.sciencedirect.com/science/article/pii/S0378874108004911

Clitoria ternatea L. (CT) (Family: Fabaceae) generally known as 'Butterfly pea', a customary Ayurvedic
prescription, has been utilized for quite a long time as a memory enhancer, nootropic, antistress,
anxiolytic, stimulant, anticonvulsant, sedating and narcotic operator. A wide scope of auxiliary
metabolites including triterpenoids, flavonol glycosides, anthocyanins and steroids has been disengaged
from Clitoria ternatea Linn. Its concentrates have a wide scope of pharmacological exercises including
antimicrobial, antipyretic, mitigating, pain relieving, diuretic, neighborhood analgesic, antidiabetic,
insecticidal, blood platelet collection restraining and for use as a vascular smooth muscle loosening up
properties. This plant has a long use in conventional Ayurvedic prescription for a few sicknesses and the
logical investigations have reconfirmed those with current importance. This audit is a push to investigate
the substance constituents, pharmacological and lethality investigations of CT, which have for some time
been in clinical use in Ayurvedic arrangement of medication alongside a basic examination of its future
ethnopharmacological potential in perspective on numerous ongoing discoveries of significance on this
outstanding plant species. (Mukherjee 2008)

Patel, K. (2018) Clitoria ternatea. Retrieved from https://examine.com/supplements/clitoria-ternatea/

According to Patel (2018) Clitoria Ternatea is one of four herbs customarily utilized as Shanka Pushpi, an
Ayurvedic prescription used to advance neurological wellbeing. It shows guarantee in creature models
for its memory upgrading impacts, and has a wide range of neurological advantages (hostile to
discouragement, anxiolytic, against pyretic) yet for these last claims primer proof recommends it isn't
excessively powerful. Some other primer proof recommends that it may be sound for the liver and
flowing lipoproteins, just as potential advantage diabetics by restraining glucose take-up from the eating
regimen. Be that as it may, these cases are excessively right on time to figure their down to earth
importance on. Toxicological examinations on rodents and chronicled use (in part frustrated with the
three different herbs) propose that Clitoria Ternatea is sheltered, yet restricted proof exists as of now.

Nguyen, T. (2019). All about butterfly pea flower — the ingredient turning food and drink true blue.
Retrieved from https://www.cbc.ca/life/food/all-about-butterfly-pea-flower-the-ingredient-
turning-food-and-drink-true-blue-1.5244451

Butterfly pea blooms are customarily utilized in Thai and Malaysian cooking styles to loan their dark blue
shading to clingy rice sweets and puddings. We mostly source this fixing from Thailand, at the same
time, contingent upon regularity and supply; the inception may shift inside Southeast Asia. Beside their
particular blue tint and otherworldly shading evolving properties, butterfly pea blossoms likewise offer a
couple of wholesome advantages. "Like other lavishly blue-hued nourishments, for example,
blueberries, the blossoms contain a high measure of anthocyanins, which are a sort of cancer prevention
agent," says De La Vega, including that in customary Ayurvedic medication, the blooms are adulated for
their "quieting and memory-boosting impacts." This lively fixing is additionally overly simple to get ready
at home. You can discover dried butterfly pea blooms on the web and in claim to fame nourishment
stores, remembering for tea and powder structure. With entire blossoms, it's simply an issue of soaking
the sprouts to make the brilliant blue refreshment or color. "Heat up the dried blossoms with water to
extricate their shading. The blooms will extend [in the water]; continue bubbling it past that point with
the goal that the whole shading is evacuated," says Regular. "At the point when you expel the blossoms
from the bubbling water and press them, no more shading should turn out — utilize that water in your
plans." The blended implantation can be delighted in as a home grown tea, joined into desserts and
puddings, utilized as the base for splendid blue drinks, or even solidified into ice 3D squares for shading
evolving lemonade. (Nguyen 2019)

Jain, NN. (2003). Clitoria and the CNS. Retrieved from

https://www.ncbi.nlm.nih.gov/pubmed/?term=Jain%20NN%5BAuthor
%5D&cauthor=true&cauthor_uid=12895670

This examination was planned for deciding the range of movement of the methanolic concentrate of
Clitoria ternatea (CT) on the Central Nervous System (CNS). The Clitoria ternatea was read for its impact
on subjective conduct, nervousness, despondency, stress and spasms prompted by pentylenetetrazol
(PTZ) and most extreme electroshock (MES). To clarify these impacts, the impact of Clitoria ternatea was
additionally considered on conduct intervened by dopamine (DA), noradrenaline, serotonin and
acetylcholine. The concentrate diminished time required to involve the focal stage (move inactivity, TL)
in the raised in addition to labyrinth (EPM) and expanded segregation record in the article
acknowledgment test, demonstrating nootropic action. The concentrate was more dynamic in the article
acknowledgment test than in the EPM. The concentrate expanded inhabitance in the open arm of EPM
by 160% and in the lit box of the light/dull investigation test by 157%, showing its anxiolytic action. It
diminished the term of idleness in tail suspension test (proposing its energizer movement), decreased
pressure incited ulcers and diminished the writhing activity of pentylenetetrazol (PTZ) and most extreme
electroshock (MES). The concentrate showed inclination to decrease the power of conduct interceded
through serotonin and acetylcholine. The impact on dopamine (DA) and noradrenaline-intervened
conduct was not noteworthy. All in all, the concentrate was found to have nootropic, anxiolytic, upper,
anticonvulsant and antistress movement. Further investigations are important to disconnect the
dynamic standard liable for the exercises and to comprehend its method of activity (Jain et al., 2003).

Al-Snafi, A. (2016).  Pharmacological importance of Clitoria ternatea . Retrieved from

http://www.iosrphr.org/papers/v6i3/G0636883.pdf

A huge and expanding number of patients on the planet utilize therapeutic plants and herbs for
wellbeing reason. Thusly, logical investigation of their remedial potential, natural properties, and
wellbeing will be helpful in settling on savvy choices about their utilization (1-2). There are several
noteworthy medications and naturally dynamic mixes created from the conventional therapeutic plants.
Plant demonstrated wide scope of pharmacological exercises including antimicrobial, cancer prevention
agent, anticancer, hypolipidemic, cardiovascular, focal anxious, respiratory, immunological, calming,
pain relieving antipyretic and numerous other pharmacological impacts (3-40) . The fundamental
phytochemical screening demonstrated that Clitoria ternatea contained tannins, phlobatannin, starches,
saponins, triterpenoids, phenols, flavanoids, flavonol glycosides, proteins, alkaloids, antharaquinone,
anthocyanins, cardiovascular glycosides, Stigmast-4-ene-3,6-dione, unpredictable oils and steroids. The
plant indicated numerous pharmacological impacts including cancer prevention agent, hypolipidemic,
anticancer, calming, pain relieving, antipyretic, antidiabetic, CNS, antimicrobial, gastro-intestinal
antiparasitic, insecticidal and numerous other pharmacological impacts (Al-Snafi 2016).

Kosai, P. et al., (2015). Review on Ethnomedicinal uses of Memory Boosting Herb, Butterfly Pea, Clitoria
ternatea. Retrieved from http://www.informaticsjournals.com/index.php/jnr/article/view/480

Clitoria ternatea is one of the conventional restorative plants utilized as "Shanka Pushpi" an Ayurvedic
medication used to lift or improve neurological wellbeing. The plant contains alkaloid, flavonoid,
taraxerol, taraxerone, triterpenoid and anthocyanin as dynamic synthetic compounds that realize its
organic impacts. Its concentrates have a wide scope of pharmacological exercises including antibacterial,
against diabetic, hostile to diarrheal, against contagious, hostile to helmintic, calming, antimicrobial, cell
reinforcement, and antipyretic exercises, hypolipidemia, immunomodulatory, and wound recuperating.
This survey is an endeavor to aggregate data on different ethno restorative employments of memory
boosting herb, butterfly pea, Clitoria ternatea. (Kosai et al., 2015)

Chusak, C. et al., (2018). Acute effect of Clitoria ternatea flower beverage on glycemic response and
antioxidant capacity in healthy subjects: a randomized crossover trial. Retrieved from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759795/

Clitoria ternatea L., a characteristic nourishment colorant containing anthocyanin, showed cell
reinforcement and antihyperglycemic movement. The point of this examination was to decide the
impacts of Clitoria ternatea blossom extricate (CTE) on postprandial plasma glycemia reaction and
cancer prevention agent status in solid men. Taking everything into account, these discoveries propose
that an intense ingestion of CTE expands plasma cell reinforcement limit without hypoglycemia in the
fasting state. It additionally improves postprandial glucose, insulin and cell reinforcement status when
overwhelmed by sucrose. (Chusak et al., 2018)

Malabadi, R. et al., (2012). Antibacterial activity of silver nanoparticles synthesized by using whole plant
extracts of Clitoria ternatea. Retrieved from
https://updatepublishing.com/journal/index.php/rip/article/view/272

This investigation features the synthesis of silver nanoparticles utilizing entire plant concentrates of
Clitoria ternatea. Antibacterial movement of silver nanoparticles was evaluated by utilizing circle
dispersion strategy against Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Klebsiella
pneumoniae, since Bacillus species and S. aureus strains may cause looseness of the bowels and an
enteropathogenic type of E. coli, and Klebsiella species may cause nourishment balancing. The
aftereffects of this examination plainly show that silver nanoparticles incorporated from plant
concentrates of Clitoria ternatea has numerous pharmaceutical applications for the control of
destructive pathogens. (Malabadi et al., 2012)

Manjula, P. et al., (2013). PHYTOCHEMICALANALYSIS OF CLITORIA TERNATEA LINN., A VALUABLE

MEDICINAL PLANT. Retrieved from http://www.indianbotsoc.org/admin/uploaded/9%20P
%20%20MANJULA.pdf

Clitoria ternatea Linn. is an attractive perennial climber with conspicuous blue or white flowers. It
belongs to the family Fabaceae and commonly known as “butterfly pea” and “shankhapuspi”. It is
traditionally used to treat various ailments (Sivarajan and Balachandran 1994, Kokate 1999). The plant is
native to south-east Asia and distributed in tropical Asia including India, the Philippines and Madagascar
(Anonymous 1998). Roots, seeds and leaves of C. ternatea are commonly used in the Ayurvedic system
of medicine. Extracts of this plant have been used as an ingredient in the Ayurvedic 'Medhya Rasayana'
as a rejuvenating recipe used for treatment of neurological disorders and are considered to enhance the
intellect (Sharma and Dash 1988). The whole plant and seed extracts are used for stomatitis, piles,
sterility in females, hematemesis, insomnia, epilepsy, psychosis, leucorrhea and polyurea
(Yoganarasimhan 2000). The roots are bitter, refrigerant, laxative, intellect-promoting, diuretic,
anthelmintic, tonic and are useful in dementia, hemicrania, burning sensations, leprosy, inflammation,
leucoderma, bronchitis, asthma, pulmonary tuberculosis, ascites, fever, otalgia, hepatopathy and as a
cathartic (Nadkarni 1976). The root, stem and flower are also used for the treatment of snake bite and
scorpion sting (Morris 1999). C. ternatea has been shown to have number of pharmacological activities
such as possessing anxiolytic, antidepressant, anticonvulsant, antistress (Jain et al. 2003), sedative
(Kulkarni et al. 1988), antipyretic, antiinflammatory, analgesic (Devi et al. 2003, Gomez and Kalamani
2003), Anthelmintic (Salhan et al. 2011) and anti-microbial activities (Kamilla et al. 2009). The extract of
C. ternatea has been shown to improve learning ability, enhance memory, increase apical and basal
dendritic branches, and increase acetylcholine content and acetyl cholinesterase activity in rats (Rai et
al. 2001). The plant contains several secondary metabolites such as kaempferol and its glucoside–
clitorin, taraxerol and a lactone aparajitin (Barik et al. 2007). Seeds contain - Sistosterol, hexacosanal,
and anthoxanthin (Yoganarasimhan 2000). Phytochemical screening of medicinal plants is very
important in identifying new sources of therapeutical and industrial importance (Salhan et al. 2011).
Phytochemical analysis of methanol extract of Clitoria ternatea roots confirmed the presence of tannins
and resins and certain other constituents (Terahara et al. 1996, Uma 2009, Manalisha and Chandra
2011). The present study deals with the phytochemical analysis of different plant parts of Clitoria
ternatea for the presence of Alkaloids, Tannins, Glycosides, Resins, Steroids, Saponins, Flavonoids and
Phenols. Quantitative analysis of root extract for total Flavonoids, Saponins and Phenols and shoot,
flower and seed extract for total flavonoids was also carried out. (Manjula et al., 2013)

Kamkaen, N. et al., (2009). The antioxidant activity of Clitoria ternatea flower petal extracts and eye gel.
Retrieved from https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2832

Extracts of Clitoria ternatea (butterfly pea) blossoms are utilized in Thailand as a part of beautifying
agents and the synthetic sythesis of the blooms propose that they may have cell reinforcement action.
In this examination the potential cell reinforcement movement of C. ternatea separates and a
concentrate containing eye gel definition was researched. Fluid concentrates were appeared to have
more grounded cell reinforcement action (as estimated by DPPH rummaging movement) than ethanol
separates (IC50 values were 1 mg/mL and 4 mg/mL, individually). Fluid concentrates consolidated in to
an eye gel plan were additionally appeared to hold this action; be that as it may, it was altogether not
exactly a business antiwrinkle cream included for correlation. The all out phenolic content was 1.9 mg/g
separate as gallic corrosive reciprocals. The information from this examination bolster the utilization of
C. ternatea separates as cancer prevention agent considerations in restorative items. (Kamkamen et al.,
2009)

Gupta, GK. et al., (2010). Clitoria ternatea (L.): Old and new aspects. Retrieved from
https://www.researchgate.net/profile/Girish_Gupta2/publication/263714827_Clitoria_ternatea
_L_Old_and_new_aspects/links/0046353bbe4507c366000000/Clitoria-ternatea-L-Old-and-new-
aspects.pdf

Clitoria ternatea (L.) local to tropical Asia is a perpetual, twining home grown restorative plant, has a
long convention of utilization as a memory enhancer and anxiolytic operator. Different constituents are
found in various pieces of the plant. The dynamic compound constituents revealed from this plant are
tannins, saps, starch, taraxerol, taraxerone, alkaloids, flavonoids, saponins, proteins, anthocyanins and
starches. In customary drug, the plant is utilized in treatment of jaundice, headache, throat, eye
contaminations, skin illnesses, asthma, swollen joints, ear-throb, emissions, fever, urinary tract diseases,
blockage, snake-nibbles, cerebral pain, acid reflux, infection and focal sensory system issue. Its different
concentrates have announced number of pharmacological exercises, for example, nootropic, anxiolytic,
anticonvulsant, calming, against pyretic, mitigating, hostile to diabetic, against oxidative, hostile to
stretch, immunomodulatory, larvicidal, proteolytic, antihelmintic, diuretic, against microbial and
memory improving. The present audit is along these lines, a push to give a nitty gritty overview of the
writing on its pharmacognosy, phytochemistry, and its customary uses alongside unique accentuation
given on pharmacological exercises. Gupta et al., 2010)