FINAL EXAM NATIONALBOARD OF EXAMINATIONS

DECEMBER2O1I
AND VENEREOLOGY
DERMATOLOGY
PAPER.I
Time : llhours DVD/D/11t06t1
Max.Marks : 100
Attempt all questions in order.
Each questioncarries 10 marks.

1. a. When calculatingsamplesize in a clinicaltrial,what is meant

by:
i. Powerof study 2
ii. Levelof significance 2
b. What is meant by doing a study accordingto good clinical 3
practiceguidelines?
c. What is meantby strengthof evidenceand qualityof evidence 3
in a clinicaltrial?
2. a. Discussthe structureof desmosome. 3
b. Whatare the immunological components of a desmosome? 3
c. Whatis the roleof desmosomes in blisteringdiseases? 4

3. a. Whatis an epidermal-mblanin unit? 2

b. Discussthe structureof melanocyteunderthe followingheads:
i) Lightmicroscopyappearance 3
ii) Electronmicroscopyappearance 3
iii) Specialtechniquesto studymelanocytes 2

4. a. Discuss the characteristics of autosomal recessive 4

genodermatosis.
b. Describebrieflytechniquesused to diagnosegenodermatosis 4
antenatally.
c. Discussgeneticmosaicism 2

5. done to evaluatea child

a. Discussthe laboratoryinvestigations 5
with mechanico-bullous
disorders.
b. Discussthe laboratoryevaluationsdone to evaluatean adult 5
withimmuno-bullousdisorders.
6- A 55 yearsold farmerpresentswith a suspectedfungalinfection
on his foot. Discussthe evaluationof such a patientunderthe
followingheadings:
a. Cluesin history 1
b. Cluesin morphologyof lesions 2
c. Sample collection 1
d. Directmicroscopy 2
e. Histopathology 2
f. Otherinvestigations 2
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FINAL EXAilI NATIONALBOARDOF EXAMINATIONS
DECEMBER2011

7. Discussthe pathogenesis of psoriasisunderthe following:

a. Roleof genetic factors 3
b. Roleof T-cells 3
c. Roleof dendriticcells t
1
d. Roleof cytokines 3

8. a. Enumeratethe residentflora of skin. 2

b. Outlinethe methodsof samplingnormalflora. 2
c. Whatis the functionof normalfloraon the skin? 2
- d. Discussone diseasecausedby residentflora. 4

9. a. Enumeratethe componentsof solarrays. 2

b. Discussthe roleof UVA,UVB in health. 2
c. Discussthe roleof UVA,UVB in :
D Ageing 2
ii) Pigmentation 2
iii) Carcinogenesis 2

10. Discussthe Valueof the followingtests in evaluatinga patientof

'allergy':
a. Patchtest 4
b. Photo-patchtest 2
c. Skinpricktest 2
d. RAST 2

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FINAL EXAM NATIONAL
BOARDOF EXAMINATIONS
DECEMBER2011

DERMATOLOGY
ANDVENEREOLOGY
PAPER.II
Time :3 hours DVD/D/I1/06/rl
Max.Marks : 100
Attemptall questionsin order.
Eachquestioncarries10 marks.

1. a. What are the clinical and histopathological differences 3

betweenlentiginesand freckles?Enumeratefour syndromes
associated
with lentigines. 2
b. Enumeratefour syndromesassociatedwith caf6 a0 lait 2
macules.
c. Whatarethe clinicalfeatures
of PeutzJegher'ssyndrome? 3

2. a. Classifydermatosisof pregnancy. 2
presentation
b. Discussthe clinical of pemphigoid
gestationis. 4
c. How will you manage an 8 month pregnantwoman with 4
pemphigoid gestationis?
3. a . Discuss the differentialdiagnosipof skin lesions in- a 5
seborrhoeic
distribution.
b . Discussthe differential
diagnosisof skin lesionson pressure 5
points.
4. Tabulatethe differences
between:
a. Variegateporphyriaand porphyriacutaneatarda 5
b. Palmoplantar psoriasisand hyperkeratotic
eczema. 5

5. a. Whatarethe criteriafor makinga diagnosis

of tuberculides? 2
b . Discusspapulonecrotictuberculide
underthe followingheads:
i) Clinicalfeatures 4
ii) Biopsyfindings 2
iii) Treatment 2

6. Discussthe useof the followingdrugs:

a. Rituzimab in pemphigus 2
b. Dapsonein lichenplanus 2
c. Steroidsin toxicepidermalnecrolysis 2
d. Acyclovirin erythemamultiforme 2
e. Thalidomide in Behcet'ssyndrome 2
7. a. Classifyalopecia 2
b. Discussmedicalmanagement of differenttypesof cicatricial 4
alopecia.
c. Discussthe surgicalmanagement of cicatricial
alopecia. 4
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FINALEXAM NATIONALBOARDOF EXAMINATIONS
DECEMBER2011

8. A 38 year old t"r"i" patientneedsto be prescribedsteroidsfor

severalmonths. l

a. Whatadvicewouldyou giveheraboutusingthe drug? a)

z
b. Howwouldyou monitorher? -i i

c. what additionaldrugs would need to be given to her to

countersomeof the sideeffectsandwhy?

9. a. Classifycutaneousleishmaniasis. 2
b. what is the geographic
distribution
of leishmaniasis
in lndia? 2
c. How will you managea patientof post Kala azar dermal 6
leishmaniasis?

10. Discussthe managementof a 1g year old femalepatientwith 10

hirsutism.

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FINALEXAM NATIONALBOARDOF EXAMINATIONS
DECEMBER2011

DERMATOLOGY
AND VENEREOLOGY
PAPER.III
Time :3 hours DVD/D/11/06/lll
Max.Marks : 100
Attempt all questions in order.
Each questioncarries10 marks.

1. a. Enumeratethe bullous disordersassociatedwith internal 2

malignancies.
of pancreatictumoursas
b. Discussthe clinicalmanifestations 4
seenon the skin.
c. Discussclinicalmanifestationsof secondariesof malignant 4
tumorsseenon the skin.

2. Describethe cutaneousmanifestations
of :
a. Hypothyroidism 2
b. Addison'sdisease 2
c. Hyperthyroidism 2
d. VitaminC deficiency 2
e. Riboflavindeficiency 2

3. a. Classifyxanthomas. 2
b. Howwouldyou evaluatea patientwho presentswith multiple
tuberousxanthomas? Discussunderthe followingheads:
i) Clinicalfeaturesincludinghistory 4
ii) Laboratoryevaluation 2
iii) Systemicfeatures 2

4. a. How would you monitor a patient of ichthyosison oral 5

retinoids?
b. How would you monitora patientof pustularpsoriasison 5
methotrexate?

5. a. Discussthe extra-cutaneous of a patientwith

manifestations 10
systemicsclerosis.

6. b. Definemastocytosis 1
c. Classifymastocytosis 2
d. Whatare the criteriafor diagnosisof systemicmastocytosis? 4
e. Discuss the histopathologyof one clinical type of
mastocytosis. 3

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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER2011

7. a. Discussthe metabolism of zinc in the humanbody. 2

b. Enumerate the causesof zincdeficiency. 2
c. Discussthe clinicalfeaturesand treatmentof acrodermatitis 6
enteropathica.

8. Discussthe management of a2 yearold child,whopresentswith

recurrentskin and chestinfections.An eldersiblingof the child
also had similar severe complaintsand died of pneumonia.
Discussyouranswerunderthe followingheads:
a. History 2
b. Examination 2
c. Lab investigations,
if all facilitiesare available. 6
9. a. Discussthe stagingof mycosisfungoides. 5
b. Discussthe stagingof malignantmelanoma. 5
10. Discussthe management of :
a. Acutegeneralizedexanthematouspustulosis 2
b . Fixeddrugeruption 2
c. Steroidacne 2
d. Cyclosporineinducedhypertrichosis 2
e . Minocycline
inducedpigmentation. 2

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FINALEXAM NATIONAL
BOARDOF EXAMINATIONS
DECEMBER2011

AND VENEREOLOGY
DERMATOLOGY
PAPER.IV
Time :3 hours DVD/D/I1/06flV
Max.Marks : 100

1fffl[11i,x1":H:".'lo"l,1T"
1. of leprosyin
Discussthe manifestations
a. Kidney 2
b. Gonads 4
c. Eye 4

2. Tabulatethe differencesbetweenborderlinetuberculoidleprcisy
lepromatous
and borderline leprosyunderthe followingheadings:
a. Morphology and characterof lesions. 3
b. Nerveinvolvement 3
c. Lepromintest 1
d. Histopathology 3

3. program:
Discussthe followingaspectsof leprosyelimination
a. Elimination 1
b. Eradication 1
c. New casedetectionrate. 1
d. Disability
in lepr:osy 2
e. Newparameters used. 5

4. of leprosyin the followingsituations:

Discussthe management
a. Pregnancy 2
b. Type 1 reaction 4
' c. Type 2 reaction 4

5. Discussthe pathogenesis
of nervedamagein leprosy. 10

6. A 19 year old sexuallyactive male presentswith a laboratory

reportof HIV positive.Howwouldyou :
a. Clinicallyevaluatethe patient 3
b. Counselhim 2
c. Investigatehim 5

7. testsavailablefor diagnosisof:
Discussthe serological
a. Syphilis 4
b. C-hlamydia infection
trachomatis 3
c. Herpesgenitalis 3
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FINALEXAM NATIONALBOARDOF EXAMINATIONS
DECEMBER2011

8. a. Classifyanogenitalwarts. 2
b. Discussthe management of anogenitalwarts in a pregnant 5 ;
woman.
c. Discussthe complications of anogenitalwarts
in a male.
9. a. Discussthe recommendation of partnermanagement
in:
i) Syphilis. 2
-,
ii) Urethraldischarge. 2
iii)Vaginaldischarge 2
b. Discus!the recom"mendations for presumptive
management 4
of sexuallytransmitted
infections.
1 0 . Tabulatethe differencesbetween:
a. Ulcersof Chancreand chancroid 4
b. Ulcersof dwarfchancroidand herpesgenitalis. 3
c. Buboof chancroidand lymphogranuloma venereum. 3

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