7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

Pharmacology-II (PR) (Subject Code :

BP507P) Batch - E
Dr, BATU, Lonere
* Required

1. Full Name of Student ( Surname / Name / Middle name) *

2. PRN Number *

3. College Roll Number *

Pharmacology-II (PR) (Subject Code : BP507P)

4. Which one of the following drugs increase digoxin plasma concentration by a

pharmacokinetic mechanism? *

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Captopril

Hydrochorothiazide

Lidocaine

Quinidine

Sulfasalazine

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

5. A treatment of angina that consistently decreases the heart rate and can prevent
vasospastic angina attacks is .... *

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Isosorbide dinitrate

NIFedipine

Nitroglycerin

Propranolol

Verapamil

6. In a patient receiving digoxin for congestive heart failure, condition that may
facilitate the appearance of toxicity include .... *

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Hyperkalemia

Hypernatremia

Hypocalcemia

Hypomagnesemia

All of the above

7. Low concentrations of heparin selectively interfere with the following coagulation

pathway(s) *

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Intrinsic pathway

Extrinsic pathway

Common pathway

No any pathway

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

8. Low doses of heparin prolong *

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Bleeding time

Activated partial thromboplastin time

Prothrombin time

Blood pressure

9. Which of the following can be used to antagonize the action of heparin in case of
overdose ? *

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Heparin sulfate

Dextran sulfate

Protamine sulfate

Ancrod

10. Blood level of which clotting factor declines most rapidly after the initiation of
warfarin therapy *

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Factor VII

Factor IX

Factor X

Prothrombin

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

11. The following drug reduces the effect of oral anticoagulants *

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Broad spectrum antibiotic

Cimetidine

Aspirin

Oral contraceptive

12. The most definite beneficial results are obtained in the use of anticoagulants for
the following purpose *

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Prevention of recurrences of myocardial infarction

Prevention of venous thrombosis and pulmonary embolism

Cerebrovascular accident

Retinal artery thrombosis

13. Anticoagulants are indicated in

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Immobilized elederly patients

Buerger’s disease

Stroke due to cerebral thrombosis

All of these

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

14. The most important complication of streptokinase therapy is *

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Hypotension

Bleeding

Fever

Anaphylaxis

15. The preferred route of administration of streptokinase in acute myocardial

infarction is *

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Intravenous

Subcutaneous

Intracoronary

Intracardiac

16. Aspirin prolongs bleeding time by inhibiting the synthesis of *

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Clotting factors in liver

Prostacyclin in vascular endothelium

Cyclic AMP in platelets

Thromboxane A2 in platelets

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

17. Route of heparin administration is *

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Oral

Subcutaneous

Intramuscular

Sublingua

18. Severe cases of bleeding due to fibrinolytic agents are treated with *

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Aspirin

Heparin

EACA (Epsilon Amino Caproic Acid)

Vitamin K

19. Hydroxyethyl starch is a *

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Plasma expander

Haemostatic

Heparin substitute

Bile acid sequestrant

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

20. All of the following are generalmechanisms of drug permeation Except *

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Aqueous diffusion

Aqueous hydrolysis

Lipid diffusion

Pinocytosis or endocytosis

Special carrier transport

21. Distribution of drugs to specific tissues *

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Is independent of blood flow to the organ

Is independent of the solubility of the drug in that tissue

Depends on the unbound drug concentration gradient between blood and tissue

Is increased for drugs that are strongly bound to plasma proteins

Has no effect on the half-life of the drug

22. The following are excreted faster in basic Urine *

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Weak acids

Strong acids

Weak Bases

None of the above

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch - E

23. “Nicotinic” sites include all of the following except *

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Bronchial smooth muscle

Adrenal medullary cells

Parasympathetic ganglia

Skeletal muscle

Sympathetic ganglia

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