Dementia with Lewy bodies 

is a common dementia characterized by changes in
sleep, behavior, cognition, movement, and automatic bodily functions. Symptoms worsen over
time until cognitive decline interferes with normal daily functioning. The core features are REM sleep
behavior disorder (in which people act out their dreams), visual hallucinations, marked fluctuations
in attention or alertness, and parkinsonism. The exact cause is unknown, but involves deposits of
abnormal clumps of protein in the brain, known as Lewy bodies. Gastrointestinal and heart function
can be affected. Definitive diagnosis usually requires an autopsy, and a probable diagnosis—based
on symptoms and tests—is often missed. Management of the many symptoms is challenging and
involves multiple specialties. There is no cure or medication to stop the disease progression. After
the suicide of Robin Williams (pictured) in 2014, his autopsy found that diffuse Lewy bodies
explained his symptoms. (Full article...)
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