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Introduction
Abruptio placenta is a condition that occurs during the 3 rd trimester of pregnancy. It is where the placenta
immaturely separates from the uterus after 20 weeks of gestation. The signs and symptoms of abruption placenta
are: sharp stabbing pain, rigid board-like abdomen (Couvelar’s sign), and dark red blood. The causes of placenta
abruption are normally trauma or injury to the abdomen. Rapid loss of fluid that surround and cushions the fetus in
the uterus (amniotic fluid) can also increase the risks for abruptio placenta. Smoking also contributes to the
possibility of developing placental abruption as the chemicals (nicotine or tobacco) causes vasoconstriction to the
uterine and umbilical arteries which aids in the premature separation of the placenta. There are three types of
abruption placenta, total abruption, central/concealed abruption, and marginal abruption. Total abruption is where
the placenta completely covers the cervix. Marginal placenta abruption is where the placenta is near the edge of the
cervix. While the central/concealed abruption placenta is where the placenta remains bleeding within the uterus and
forms a clot retroplacentally. With this type, bleeding may not be visible, but may become severe and could lead to
systemic shock.
II. Objectives
General:
Abdominal pain
Back pain
Uterine tenderness or rigidity
Dark red vaginal bleeding
VI. Pathophysiology
Drug Name Classification Indication and Side Effects and Special Nursing
and contraindications Adverse Effects Precautions responsibilities
Mechanism of
Action
Generic Name: Classifications: Indications: Headache Drug should MIO with patients
Ketorolac Non-steroidal For pain and Nausea be adjusted with a history of
Tromethamine anti- inflammation after Diarrhea for patients cardiac
inflammatory surgery Dizziness 65 years old decompensation,
Brand Name: drug Pruritus and older, renal impairment,
Toradol Contraindications: Edema patients heart failure, or
Actions: Cardiovascula Drowsiness under 50 kg liver dysfunction
Dosage: 30 mg Treats r thrombotic Hypertension of body
moderately events, MI, weight, and Monitor for signs
Route: IV severe pain and and stroke patients of GI distress or
inflammation GI issues with bleeding, nausea,
Frequency and after surgery. It For moderately GI pain, diarrhea,
timing: Every 6 blocks the prophylactic elevated melena, or
hours for 3 days production of analgesic serum hematemesis
prostaglandins Renal creatinine
which causes problems Ask patient to not
pain, fever, and drive
inflammation
Generic Name: Classifications: Indications: Diarrhea Caution the Assess patients
Mefenamic acid A fenamate Mild to moderate pain, Constipation patient to who develop
groups of including menstrual Gas or call their severe diarrhea
Trade/Brand NSAIDs pain, fever, and bloating doctor if and vomiting risk
Name: Ponstel inflammation Headache experiencin for dehydration
Actions: Dizziness g chest pain and electrolyte
Dosage: 500 mg Exhibits anti- Contraindications: Nervousness or imbalance
inflammatory, Patients with salicylate Ringing in the discomfort,
Route: Orally analgesic, hypersensitivity or ears nausea and Perform lab tests
antipyretic NSAID hypersensitivity, vomiting, for normal results
Frequency and activities. asthma, urticarial, or pain in
timing: 1 tablet Inhibits other allergic reactions arms, jaw, Notify doctor if
every 6 hours prostaglandin to aspirin or NSAIDs back, or persistent GI
synthetase. neck, discomfort, sore
shortness of throat, fever, or
breath, malaise
slurring of
speech or Do not drive
weakness.
Monitor blood
glucose levels for
loss of glycemic
control if diabetic
Generic Name: Classifications: Indications: Rash History of Culture infection,
Cefuroxime Cephalosporin Tonsillitis, acute Fever hypersensit- and arrange for
antibiotics bacterial maxillary Pruritus ivitiy to sensitivity tests
Dosage: 500 mg sinusitis, bronchitis, Erythema penicillin, before and during
Actions: uncomplicated GI bleeding and GI therapy
Route: Orally Inhibits pneumonia, skin and infection disease
bacterial cell structure infections, Abdominal (colitis), Taken with food
Frequency and wall synthesis uncomplicated UTI, pain renal to decrease GI
timing: Every 8 by binding to gonorrhoea Flatulence impairment upset and
hours one or more Indigestion enhance
penicillin- Contraindications: Thirst absorption
binding Hypersensitivity to Dyspepsia
proteins to cefuroxime or other Sleepiness Have vitamin K
inhibit the cephalosporins Thrombocyto available in case
synthesis of penia of
bacterial cell hypoprothrombin
walls which emia occurs
leads to
bacterial cell Discontinue if
death hypersensitivity
reaction occurs
Generic Name: Classifications: Indications: Nausea Caution in May be taken
Hemarate Over-the- Iron deficiency anemia, Vomiting those with after food to
counter folate deficiency, and Bloating and chronic liver reduce GI side
Dosage: 500 mg supplement lowering of plasma upper failure, effects
homocysteine abdominal alcoholic
Route: Orally Actions: discomfort cirrhosis, May experience
Iron, vitamin B Contraindications: Diarrhea or chronic discoloured stools
Frequency and and folic acid Allergic to any constipation alcoholism,
timing: Once a prevents and ingredient of the drug. and
day treats iron- Iron supplement pancreatic
deficiency avoided in condition insufficiency
anemia and associated with iron
vitamin b- overload
complex
deficiencies to
produce
healthy blood
and synthesis
of hemoglobin
Generic Name: Classifications: Indications: Nausea Not given Monitor
Isoxsuprine Are For pre-term labor or Vomiting during therapeutic
vasodilators peripheral vascular Nervousness preterm effectiveness
Trade/Brand diseases Weakness labor if
Name: Duvadilan Actions: Rash there is an Monitor BP and
Increases the Contraindications: Breathlessnes infection. pulse, can cause
Dosage: 10 mg flow of blood in To patients who are s hypotension and
blood vessels allergic to isoxsuprine, Tightness in tachycardia
Route: Orally and uterine have hypotension or the chest
relaxant an artery that bleeds, Chest pain Observe both
Frequency and rapid heartbeat or any Irregular mother and baby
timing: Every 6 condition that leads to heartbeats for any
hours bleeding Flushing irregularities in
Severe vital signs
dizziness
Decreased
calcium