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What is vaccination? How does a vaccine work?

Vaccination is a simple, safe, and effective way of Vaccines reduce risks of getting a disease by working with your body’s
protecting people against harmful diseases, before natural defenses to build protection. When you get a vaccine, your immune
they come into contact with them. It uses your body’s system responds. It:
natural defenses to build resistance to specific
infections and makes your immune system stronger.  Recognizes the invading germ, such as the virus or bacteria.
 Produces antibodies. Antibodies are proteins produced naturally by
Vaccines train your immune system to create the immune system to fight disease.
antibodies, just as it does when it’s exposed to a  Remembers the disease and how to fight it. If you are then exposed
disease. However, because vaccines contain only to the germ in the future, your immune system can quickly destroy it
killed or weakened forms of germs like viruses or before you become unwell.
bacteria, they do not cause the disease or put you at
risk of its complications.
The vaccine is therefore a safe and clever way to produce an immune
response in the body, without causing illness.
Most vaccines are given by an injection, but some are
given orally (by mouth) or sprayed into the nose.
Our immune systems are designed to remember. Once exposed to one or
more doses of a vaccine, we typically remain protected against a disease for
years, decades or even a lifetime. This is what makes vaccines so effective.
Why is vaccination important? Rather than treating a disease after it occurs, vaccines prevent us in the first
instance from getting sick.
Vaccination is a safe and effective way to prevent
disease and save lives – now more than ever. Today
there are vaccines available to protect against at least Why should I get vaccinated?
20 diseases, such as diphtheria, tetanus, pertussis,
influenza and measles. Together, these vaccines save Without vaccines, we are at risk of serious illness and disability from
the lives of up to 3 million people every year. diseases like measles, meningitis, pneumonia, tetanus and polio. Many of
these diseases can be life-threatening.
When we get vaccinated, we aren’t just protecting
ourselves, but also those around us. Some people, Although some diseases may have become uncommon, the germs that cause
like those who are seriously ill, are advised not to get them continue to circulate in some or all parts of the world. In today’s world,
certain vaccines – so they depend on the rest of us to infectious diseases can easily cross borders, and infect anyone who is not
get vaccinated and help reduce the spread of disease.  protected

During the COVID-19 pandemic, vaccination Two key reasons to get vaccinated are to protect ourselves and to protect
continues to be critically important. The pandemic those around us. Because not everyone can be vaccinated – including very
has caused a decline in the number of children young babies, those who are seriously ill or have certain allergies – they
receiving routine immunizations, which could lead to depend on others being vaccinated to ensure they are also safe from vaccine-
an increase in illness and death from preventable preventable diseases.
diseases.

What diseases do vaccines prevent?


Who can get vaccinated?
Vaccines protect against many different diseases,
Nearly everyone can get vaccinated. However, including:
because of some medical conditions, some people
should not get certain vaccines, or should wait before  Cervical cancer
getting them. These conditions can include:  Cholera
 COVID-19
 Chronic illnesses or treatments (like  Diphtheria
chemotherapy) that affect the immune  Hepatitis B
system;  Influenza
 Severe and life-threatening allergies to  Japanese encephalitis
vaccine ingredients, which are very rare;
 Measles
 If you have severe illness and a high fever
 Meningitis
on the day of vaccination.
 Mumps
 Pertussis
These factors often vary for each vaccine. If you’re  Pneumonia
not sure if you or your child should get a particular
 Polio
vaccine, talk to your health worker. They can help
 Rabies
you make an informed choice about vaccination for
you or your child.  Rotavirus
 Rubella
 Tetanus

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