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522 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO.

3, JUNE 2021

Textile Electromagnetic Brace for Knee Imaging


Kamel S. Sultan , Student Member, IEEE, Ahmed Mahmoud , and Amin M. Abbosh , Senior Member, IEEE

Abstract—A wearable textile brace is introduced as an elec-


tromagnetic imaging system that breaks hospital boundaries to
real-time onsite scanning for knee injuries. The proposed brace
consists of a 12-element textile slot loop antenna array, which is
designed to match the human knee for enhanced electromagnetic
wave penetration. Wool felt and conductive fabric are used to
fabricate the antenna array thanks to their flexibility and proper
dielectric properties. Each antenna element has a compact footprint
of 42 × 24 × 3.22 mm3 and achieves unidirectional radiation,
high front-to-back ratio of 14 dB, wide bandwidth of 81% at
0.7–1.7 GHz, and safe SAR levels. A modified double-stage delay,
multiply, and sum (DS-DMAS) algorithm is used to process the
collected signals from the antenna array based on differential
left/right knee imaging. The reconstructed images numerically and
experimentally on realistic phantoms demonstrate the potential
of the brace system for onsite detection of different types of lig-
aments/tendon tears.
Fig. 1. 3-D structures of the knee joint [1]; (a) Tendon view and (b) ACL/view.
Index Terms—Knee injuries, on-body matched antenna, textile
antenna, electromagnetic imaging, double-stage delay multiply and
sum algorithm. knee ligaments without obstructing natural activity reduces the
severity of the injury and its transformation into a complete tear,
I. INTRODUCTION which can only be treated by the use of interventional surgery
[3], [6]. Besides, the treatment period is shortened from nearly
HE knee is prone to injuries more often than other joints
T in the body due to its complexity and weight-bearing role.
These injuries are not only inherent to sport fields but also can oc-
one year in the case of full tears (Grade III) to several weeks
in the case of mild or moderate tears (Grade I and Grade II).
Moreover, early detection decreases the risk of other injuries
cur during activities of daily living. The tissue at the level of the that are associated with full ligament tears, such as meniscal
knee joint includes skin, subcutaneous fat, fascia, extraarticular and tendon tears, posttraumatic osteoarthritis, and dislocation
and intraarticular ligaments (see Fig. 1). The main extraarticular [4], [7].
ligaments include the medial collateral ligament (MCL), lateral Current modalities to detect and image the connective tissue
collateral ligament (LCL), and medial patellofemoral ligament. tearing include magnetic resonance imaging (MRI) as a golden
The interarticular ligaments include the posterior cruciate liga- standard tool. As much as MRI has the capability to detect liga-
ment (PCL) and anterior cruciate ligament (ACL). The tendons ment injury with an average accuracy of 85%, its high cost and
of the hamstrings, quadriceps, and gastrocnemius act across the bulky size make it unsuitable for onsite early detection [8]–[10].
knee joint [1]–[4]. Ligament tears are the common knee injury The other modalities like computed tomography (CT) and X-ray
with more than 6 million lacerations per year and considered don’t have the capability to detect connective tissue tears. Also,
the most violent because of the need for long-term treatment ultrasound has limitations in detecting all knee tissues, and it is
(9-12 months) [5], [6]. Early detection of a partial tear for limited to detect outer tissues [11].
Electromagnetic imaging (EMI) has undergone rapid devel-
Manuscript received March 14, 2021; revised April 26, 2021 and May 25, opment and become one of the promising biomedical imaging
2021; accepted May 26, 2021. Date of publication June 2, 2021; date of current
version August 17, 2021. This work was supported by an Australian Government modalities over the past two decades because of its unique
Research Training Program Scholarship. (Corresponding author: Kamel S. features, such as low cost, simple structure, portability, and
Sultan.) non-ionization. Thus, EMI has been investigated for the early
Kamel S. Sultan and Amin M. Abbosh are with the School of Information
Technology and Electrical Engineering, University of Queensland, Brisbane detection/monitoring of strokes, skin cancer, heart failure, breast
QLD 4072, Australia (e-mail: k.sultan@uq.ed.au; a.abbosh@uq.edu.au). cancer, bone fracture, and pulmonary edema [12]–[22]. EMI
Ahmed Mahmoud is with the School of Medicine, Griffith University (A.M.), modality is based on the significant changes in dielectric char-
Gold Coast, QLD 4222, Australia, Brisbane Orthopaedic and Sports Medicine
Centre, The Brisbane Private Hospital (J.Y., P.M.), Brisbane, QLD 4000, Aus- acteristics of tissues due to abnormality or injuries. For knee in-
tralia, and Active Rehabilitation Physiotherapy (J.B-S.), South Brisbane, QLD juries, when the ligament/tendon tear happens, the synovial fluid
4000, Australia (e-mail: a.mahmoud@uq.edu.au). increases inside the knee joint. Specifically, it is a haematoma-
Color versions of one or more figures in this article are available at https:
//doi.org/10.1109/TBCAS.2021.3085351. a mixture of blood and synovial fluid, leading to knee effusion
Digital Object Identifier 10.1109/TBCAS.2021.3085351 and changes in its dielectric properties [23, 24]. Therefore, EMI
1932-4545 © 2021 IEEE. Personal use is permitted, but republication/redistribution requires IEEE permission.
See https://www.ieee.org/publications/rights/index.html for more information.

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 523

is investigated here as a tool that may overcome the limitations


of current modalities. Although few initial works are introduced
in the literature to investigate the use of EMI to detect tear or
defect of some knee tissues, such as tendon [25], meniscus [26],
[27], and artificial meniscus [28], those studies didn’t introduce
an applicable study in real life as those are limited in scope
to extracted individual tissue outside the knee joint without
considering of surrounding tissues.
The key elements of EMI systems are imaging algorithms and Fig. 2. Overview of the proposed textile wearable system for knee injuries.
antenna array. Specifically, EMI algorithms can be divided into
radar-based and tomography-based algorithms. The radar-based
(DMAS), coherence factor (CF), and differentiate between the
algorithms require wide bandwidth antennas [12], [29] while the
left and right human knees are used to reconstruct the images.
tomography-based algorithms require a single frequency [30] or
The reconstructed images prove the ability of the proposed brace
multiple frequencies [31], [32]. Thus, a wide bandwidth antenna
system to detect different types of knee injuries.
with unidirectional characteristics is the main candidate to fulfill
The remaining parts of this paper are organized as follows.
the different types of the aforementioned algorithms. Several
Section II presents an overview of the proposed electromagnetic
types of antennas were introduced to meet those requirements,
brace system in addition to more details about knee structure and
such as Vivaldi antennas [33], cavity-backed antennas [34], 3D
its dielectric characteristics. In section III, the antenna design
structure antenna [35], log-periodic [36], monopole integrated
procedure, textile material characteristics, fabrication process,
with reflector [37], [38]. Most of these antennas have large
evaluation of antenna performance in presence of knee phan-
profiles and heavy structures that limit the number of antenna
tom and human knee are introduced. The modified microwave
array elements around the imaged object. Additionally, they
algorithm and the reconstructed images of different scenarios of
suffer from a low front-to-back ratio that reduces the penetration
knee injuries in the simulation and experimental environment
of EM signals inside tissues under test.
are evaluated and discussed in section IV. Finally, section V
An alternative approach for EMI antennas is on-body matched
presents the concluded remarks.
antennas which reduce skin interface reflections [39]–[45].
The reported antennas have restrictions in terms of large size,
back radiation, complicated structure, and conformality with II. OVERVIEW OF BRACE EMI SYSTEM AND KNEE STRUCTURE
the body. For instance, the antennas reported in [40], [41] are A schematic diagram of the proposed brace system is shown in
partial/slotted ground antennas, which means the EM signals Fig. 2. It is fabricated from a textile material that is worn around
don’t effectively penetrate inside the tissues under test, whereas the knee and includes a 12-element antenna array. Thanks to
the antennas in [39]–[42] have a relatively large size. On the its flexibility, the proposed wearable brace can fit with different
other hand, the reported antenna in [43] is fabricated on a home- knee sizes. The antennas are connected to multiport VNA. The
made thick substrate and high dielectric constant which leads to backscattered signals that describe the characteristic of knee
reduced radiation efficiency and changing characteristics over tissues are gathered and stored using a laptop. A modified double
time. Therefore, a new antenna that can fit with the dielectric stage confocal algorithm is used to differentiate between the left
characteristic of the knee joint and conformal shape is required. and right knee joints (normal and abnormal joints) to reconstruct
Otherwise, a lower microwave frequency around 1 GHz with the knee image. This differential method is used here thanks
wide bandwidth is recommended for EMI systems to increase to the fact of anatomical similarity between the left and right
penetration with low specific absorption rate (SAR) values and knees with more than 98% correlation [46], [47]. To achieve
improve the reconstruction images. the balance tradeoff between the spatial imaging resolution
This paper presents a non-invasive wearable textile brace for and electromagnetic penetration inside the knee tissues, the
electromagnetic imaging of knee injuries. Since the proposed operating frequency is selected to be around 1 GHz with wide
system is a wearable brace, it is designed to be in direct contact bandwidth.
with the knee. The proposed brace consists of a 12-element
slot-loop antenna array that is fabricated on flexible wool felt
substrate. In addition to the wide bandwidth of the antenna A. Structure and Dielectric Properties of Knee Joint
(0.7–1.7 GHz), it exhibits unidirectional characteristics in the Since changes in the dielectric properties of tissues are the
near field and safe SAR values. Besides the brace, the proposed main factor in EMI, an extensive study of the knee structure and
system consists of a multiport vector network analyzer (VNA) its tissue characteristics is vital before starting in system design.
and host PC. The operating frequency of the proposed system Thus, 150 transverse slices with a total height of 15 cm from the
provides a reasonable compromise between the penetration of MRI Duke voxel knee model that has 1 mm × 1 mm × 1 mm
microwave signals into the knee and spatial resolution of recon- resolution [48] were imported into MATLAB© and mapped with
structed images. The system is verified experimentally using the relative dielectric properties for each tissue from [48], [49].
durable knee and liquid knee phantoms with different types A dielectric profile of the three different knee planes (Sagittal,
of connective tissue tearing. A modified algorithm based on Coronal, and Axial) are depicted in Fig. 3 to present the variation
the combination of double stage delay multiply, add and sum of relative permittivity and conductivity at 1.2 GHz (the center

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524 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO. 3, JUNE 2021

Fig. 4. Setup configuration of the proposed antenna in presence of knee model


(a) One-layer knee model and the average dielectric properties of the knee, (b)
Multilayer knee model, (c) Realistic knee model.

properties of injured knee with torn ACL/PCL ligaments and


tendon, and thus have accumulated synovial fluid (water). It is
clear to note that the injured areas have high dielectric contrast
compared to surrounding tissues and healthy knee.
The knee has heterogeneous tissues with irregular distribution
around its center. Also, the thickness of knee tissues differs
between individuals. Thus, the antenna is designed and opti-
mized in three different models simultaneously; (I) Model 1: a
one-layer model that emulates the average dielectric properties
of knee tissues (Fig. 4(a)), (II) Model 2, a multilayer model
that emulates all knee tissues in the axial plane, considering the
thickness of each tissue and its dielectric properties (Fig. 4(b)),
and (III) Model 3, 3-D realistic voxel model (Fig. 4(c)). For the
first model, the average dielectric properties for the knee tissues
is calculated from (1):
L   T εi (w)−jεi (w)

k=1 i=1 di D
εav (ω) = k
(1)
L
Fig. 3. Dielectric profile for human knee joint (relative permittivity and where εav refers to the average complex permittivity, k and i
conductivity) at the center of the used band (f = 1.2 GHz) in different planes: denote the index number of knee layers and tissues, respectively,
(a) Sagittal plane of a normal knee, (b) Coronal plane of a normal knee, (c) Axial whereas L is the total number of axial slices (70 slices), T is the
plane of a normal knee, and (d) Axial plane of an injured knee. Left and right
images present relative permittivity and conductivity of the knee joint before number of different tissues in each slice, d is the tissue thickness,
tear, respectively. While the read shapes (circles\ellips) refer to the location of and D is the total thickness of all tissues in the slice. The average
ligaments. The first colour bar is for the normal kne, whereas the second colour dielectric properties of the knee are shown in (Fig. 4(a)). For the
bar for the injured knee.
second and third models, the maximum and minimum values of
dielectric properties for main knee tissues across the investigated
of the interested band of operation). Once the ligament tear
frequency band are listed in Table I.
happens, synovial fluid with blood (Haematoma fluid) starts
to accumulate at the location of the tear, inside the dotted red
III. KNEE MATCHED SLOT LOOP ANTENNA
regions (see Fig. 3) then starts to fill the whole knee joint and
causes knee effusion [2], [50]. This fluid leads to a change in the This section describes the criteria to design a wideband, uni-
dielectric properties of the knee joint due to its high dielectric directional, and wearable antenna for knee imaging. Firstly, the
properties (εr = 84 and σ = 2.3 s/m) [48] compared to low dielectric properties of the used substrate are measured followed
dielectric of other knee tissues. Fig. 3(d) shows the dielectric by antenna design and studying its performance in different

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 525

TABLE I
DIELECTRIC PROPERTIES OF THE KNEE TISSUES OVER THE INTERESTING
FREQUENCY RANGE (0.7–1.8 GHZ)

Fig. 6. Front configuration of the proposed slot loop antenna with full ground
plane.

TABLE II
DIMENSIONS OF ANTENNA PARAMETERS (MM)

B. Antenna Configuration and Operation Principle


To achieve wide operating bandwidth and directional radi-
ation patterns, a full grounded slot loop antenna is introduced.
The proposed antenna is designed on 3 mm thick wool felt textile
material with a low-profile structure (42 × 24 × 3.22 mm3 ) to
operate around 1 GHz. Fig. 6 and Table II show the configu-
ration of the antenna and its related dimensions, respectively.
Fig. 4(a-c) depicts the simulation setup when the antenna is in
Fig. 5. Measured dielectric properties of Wool Felt substrate using DAK (a) contact with knee models. All simulations were carried out using
measurement setup and (b) relative permittivity and loss tangent of the Wool
Felt substrate. CST Microwave Studio. The fabric conductive surfaces of the
antenna are modeled as a resistive sheet, while the measured
dielectric characteristics of wool felt are imported and assigned
scenarios. Secondly, the fabrication process and measurements for the substrate.
of the antenna in presence of knee models are presented. To understand the implicit performance of the antenna, the
design criteria are presented step by step as shown in Fig. 7(a).
A. Material Properties In specific, the design started with a simple two slot-loops full
ground backed structure, which typically leads to the wide band-
For the proposed antenna, a conductive fabric sheet (Silver width and unidirectional radiation. The feed point is selected at
Nylon Ripstop Fabric) with a thickness of 110 μm and surface the center of the antenna to achieve symmetry between antenna
resistivity less than 0.03 Ω/square is used to serve as the parts and keep them in a parallel connection using a 50 Ω coaxial
radiating patch and ground plane. This fabric conductive sheet connector. To reduce the radiating element length, two shorting
is robust enough to stay undeformed for several uses and thus pins (vias) at the edge of the loop slot (marked as V in Fig. 6)
ensures durability of the antenna [51]. Textile wool felt sheet are used. With the shorting pins, the slot loop antenna operates
with a thickness of 3 mm serves as the dielectric substrate for in a magnetic current loop mode. The circumference and the
the antenna and offers high flexibility and robustness as proven in edge length of the slot loop are the two main parameters to
several applications [40], [41], [51], [52]. A conductive thread is control the resonance modes of the antenna. They are calculated
used to serve the shorting pins between the patch and the ground as ci = [L1 + 2(L2 + L3 ) + Wd ] = 0.5λg and L1 = 0.25λg ,
by sewing. An initial step to measure the dielectric properties respectively, λg is the guided wavelength calculated as in (2):
of the wool felt substrate is performed using SPEAG dielectric
assessment kit (DAK), (see Fig. 5(a)). As shown in Fig. 5(b), c
λg ≈  (2)
the measured average relative permittivity and tangential loss εrs (f)+εav (f)
f∗ 2
are 1.65 and 0.001, respectively. The textile material is selected
here because of its flexibility, conformability, and soft-touch where εrs and εav are the dielectric constant of Wool Felt
properties. substrate and knee model, respectively, f is frequency, and c

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526 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO. 3, JUNE 2021

Fig. 8. Simulated reflection coefficient of the proposed antenna with different


knee models.

Fig. 9. Reflection coefficient and bent view of the proposed antenna with a
different bent radius.

gap width is optimized to achieve real impedance close to 50


Ω and reduce the imaginary part (see Fig. 7(b and c)) which
leads to improved impedance bandwidth of 81% (from 0.736 to
1.738 GHz).
Fig. 7. Simulated results (a) reflection coefficients of the proposed antenna
step by step, (b) and (c) real and imaginary part of input impedance. The antenna
Performance of the antenna in the presence of knee is depicted
is loaded by the first knee model. in Fig. 8. The aforementioned three knee models are used. The
reflection coefficients indicate that knee model 1 has better
matching than the other two models especially at the second
is the speed of light. Fig. 7(a) shows that Ant. A operates around operating mode (1.55 GHz). Although the proposed antenna is
1.25 GHz with a wide bandwidth from 1.1 GHz to 1.6 GHz. It can designed using different equivalent three models, the three cases
be observed that the antenna generates two close modes that give have the same bandwidth at −10 dB reference. As the proposed
a wide bandwidth. To increase the bandwidth and maintain the antenna is designed on a flexible brace, and it is expected to be
same size, a tuning stub is added to the antenna structure (Ant. B worn by humans, it is supposed to be conformed and bent to
and Ant. C) to tune its input impedance, along with improving the the knee surface. Thus, it is essential to study the performance
matching of the second mode. Although the antenna has a wide of the antenna during bending. Therefore, the antenna is bent
bandwidth, its input impedance has a high inductance part due to R (mm) radius of a cylinder model that emulates the average
to using 3.22 mm long wires of feed probe and vias as depicted dielectric properties of knee tissues. Fig. 9 indicates the influence
in Fig. 7(b and c). To reduce the inductance, a rectangular gap is of bending on the performance using CST. Changing the bending
etched around the feed probe to introduce a series capacitance radius from 40 mm to 70 mm did not change the antenna’s
with the input impedance [53] (see Ant. D in Fig. 7(a)). The performance significantly.

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 527

Fig. 10. Fabrication process (a) laser cutting machine engraver speedy 500,
fabric conductive sheet is fixed on the platform, (b) prototype of conductive parts
and (c) fabricated prototype attached with SMA connector using conductive
epoxy.

Fig. 12. Reflection coefficient of the fabricated antenna (a) different cases
to fabricate shorting pins (VIAs), (b) the fabricated antenna attached to the
Fig. 11. Measurement setup for a single element textile antenna in the vicinity phantom.
of a 3-D realistic phantom of the left knee (healthy).

(kneecap) as adopted in Fig. 11. Then, the antenna is connected


C. Fabrication Process and Measured Results
to VNA and the reflection coefficients are measured as shown
A laser cutter (Laser Engraver speedy 500) is used to trim in Fig. 12 and compared with the simulated results. A good
the fabric conductive sheet and pattern the required structure agreement between them is noted with a slight mismatch due
(see Fig. 10(a)). A sticky tape of 0.05 mm is used to protect and to the slight difference between the dielectric properties of the
support the conductive fabric sheet during the trimming process simulated knee model and fabricated phantom. Nevertheless,
then used to attach the fabricated pattern to the textile substrate to the simulated and measured results show approximately the
avoid shape distortion. Thanks to the high-resolution laser trim same operational bandwidth using −10 dB as the reference.
mechanism and interwoven thread bundles fabric conductive After validating the antenna design, the optimum number
sheet, any restriction to fabricate the critical dimensions of of antenna array elements that fit an average knee curvature,
the proposed antenna that faced previous textile antennas [42], have below −20 dB coupling and cover the same operational
[54] are avoided, resulting in an accurate prototype as shown bandwidth is selected to be 12. Thus, a 12-element antenna
in Fig. 10(b). After the adhesion of the conductor layers with array is fabricated and assembled as illustrated in Fig. 13. As
the textile substrate, the conductive epoxy CW-2400 is used to seen in Fig. 13(e and f), the antenna array is flexible even after
bond the SMA to the antenna, thanks to its excellent electrical inserting the SMA connectors. The proposed antenna achieves
conductivity and strong mechanical bonds. Finally, two holes the required balance between compact size, wide operational
were drilled in the substrate to build the shorting pins. There are bandwidth and directional pattern in addition to flexibility and
two main approaches introduced in the literature [51] to make conformity to the knee joint compared to other wearable anten-
the shorting pins; the first approach uses metallic wire, while nas in the literature [16], [34], [39], [41], [52], [56].
the second uses a conductive thread to form the vias. To assess
these approaches, two prototypes of the antenna are fabricated D. Evaluation of Antenna Performance
using the aforementioned approaches. Fig. 12(a) demonstrates
that there are no significant changes in the reflection coefficients The real part of the Poynting vector Pav (time average power
between the two approaches. Therefore, the second approach by density) is used to estimate the signal propagates inside the knee
using conductive thread is selected to complete the fabrication of joint. It refers to the power flow per unit area at a distance from
the antenna array to maintain the flexibility of the textile brace. the antenna position and it decays inversely with the distance.
To validate the performance of the antenna, it is tested in The real part of the Poynting vector is calculated as [39]:
the vicinity of a 3-D realistic knee phantom that was presented 1
recently [55]. The antenna is attached to the front of the knee P av (x, y, z) = Re (E × H ∗ ) W/m2 (3)
2

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528 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO. 3, JUNE 2021

power can be increased without significantly affect on human


safety to achieve more penetration inside the knee joint.
Since the antenna for knee imaging operates in both the near
and far fields, the near field radiation patterns are investigated
numerically and experimentally in presence of the knee model.
Numerically, the antenna is attached to the kneecap and E-field
probes are arranged along a circle with a radius r = 50 mm
that intersects the axial plane of the knee as illustrated in
Fig. 15(a). Experimentally, the MRI voxel knee model, which
was used in the numerical analysis, was converted to a CAD
model and fabricated using a 3-D printer. The fabricated model
is an anthropomorphically knee-shaped shell that is filled with
a broadband 0.29/0.71 water/glycerin homogeneous liquid to
emulate the average dielectric properties of knee tissues. The
dielectric properties of the homogeneous liquid were measured
using Keysight slim probe as shown in Fig. 15(b) and compared
to the calculated values from (1) as shown in Fig. 15(c). The
average difference between the dielectric properties of mimick-
ing liquid and calculated values from (1) is 3% and 4.5% for the
relative permittivity and conductivity, respectively.
The fabricated antenna array is attached to the knee model
Fig. 13. Prototype of the antenna array (12 elements), (a-d) before and after
the assembly with SMA connectors and VIAs, and (e-f) the bent views. to demonstrate the experimental setup which presents the real
situation for the proposed brace. One antenna and an E-field
probe are connected to the multiport VNA. The E-probe was
carried using a dynamic movable multi-section holder. More-
over, PLA holders and Acrylic base were designed and fab-
ricated to fix the proposed brace system to avoid movement
errors during the measurements as shown in Fig. 15(d). Fig. 16
illustrates the normalized simulated and measured near field at
0.9 GHz and 1.5 GHz in the XY plane. The near field radiation
patterns are symmetric, unidirectional in the Y-axis, and have
a front-to-back ratio of 14 dB. The simulated and measured
results ensure that the electromagnetic signals can penetrate
effectively into the knee tissues. The antenna achieves more
than 86% penetration efficiency (ηp ) over the whole band as
calculated using ηp = Pbody /(Pbody + Pair ), where Pbody and
Pair are the penetration power into the human body and radiated
power in free space, respectively.

Fig. 14. Calculated Poynting vector at 0.9 and 1.7 GHz for the sagittal plane IV. BRACE VALIDATION FOR KNEE INJURIES
(YZ) and axial plane (XY) (where the antenna is placed in XZ plane as shown
in Fig. 4(c)).
To demonstrate the proposed brace capabilities in the real en-
vironment, different cases of ligament tears are imaged. Numer-
ical and experimental scenarios are utilized based on a numerical
where E and H are the complex vectors of electric and magnetic
knee model, and homogenous liquid and durable phantoms. This
instantaneous fields at a point (x, y, z) , respectively. The real
section starts with an explanation of the utilized modified imag-
part of the Poynting vector is calculated as shown in Fig. 14, for
ing algorithm followed by studying different testing scenarios.
the different planes of the knee joint. To evaluate the power
penetration inside human tissues, the average power density
normalized to 10 W/m2 (10 dB W/m2 ) [39], [43]. It can be A. Electromagnetic Imaging Algorithm
noticed that the average power density is more than 6 W/m2 at The other main key in EMI is the processing algorithm, which
the center of the knee (65 mm inside the knee), which indicates analyzes the received scattered signals to reconstruct the image.
sufficient penetration depth. On the other hand, the specific The utilized algorithm is described in detail in Fig. 17. Since
absorption rate (SAR) is calculated to check the safety of using left/right knees have anatomical symmetry with more than 0.98
the antenna with the standard regulation by IEEE C95.1-1999 correlation [46], [47], [58], [59], along with the fact that bilateral
(<2 W/kg), [57]. The maximum SAR is 0.065 W/kg (10 g) ligament tears that happen simultaneously are extremely rare
when the input power to the antenna was 10 dBm which is well [60], the differential algorithm [56, 61] between normal and
within the safe level as per the standard [57] and means the input injured knee is a realistic approach to remove clutter from

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 529

Fig. 16. Simulated and measured near-field radiation patterns of the antenna
in presence of knee models (XY plane).

where V (t) refers to the backscattered signal received at the


antenna, subscripts U and H denote to unhealthy (abnormal)
and healthy (normal), respectively, and ( ) refers to the mirror of
the matrix, while subscript m refers to the order of backscattered
signal in the scattered matrix.
A modified double-stage delay-multiply-and-sum (DS-
DMAS) algorithm is used to reconstruct knee images. Starting
from the concept of multi-static radar-based algorithms, DMAS
can be expressed as, [62], [63]:

M −1 
M
YDM AS (t) = Si (t) Sj (t) (5)
i=1 j=i+1


M −1 
M
YDM AS (t) = Si (ti (r)) Sj (tj (r))
i=1 j=i+1

= S1 (t) [S2 (t) + S3 (t) + · · · + SM (t) ]


+ S2 (t) [S3 (t) + S4 (t) + · · · + SM (t) ]
+ ···
+ SM −1 (t) [SM (t)] (6)
where Y is the output signal after applying DMAS, M is the
total number of scattered signals, while i, and j refers to the
order of multiplied signals (To simplify the writing of equations,
each τ (r) is replaced t). After applying the multiplication, the
dimensionality of the obtained signal is squared. Therefore, the
signed square root for each signal is calculated [63] to keep the
sign of signals and the square root is used to correct the signal
dimensionality like the input signals Si or Sj . The signals after
signed term are expressed as:

Fig. 15. Near-field radiation pattern setup, (a) simulation setup, (b) measure- YDM AS (t) = X1 (t) + X2 (t) + · · · + XM (t) (7)
ment system setup of homogenous knee model (liquid: Glycerin and water), (c)
dielectric properties of the liquid phantom, and (d) experimental setup of the where Y  is the output of DMAS after applying signed process,
near-field radiation pattern. X1 (t), X2 (t), . . . . XM (t) refer to terms number 1, 2, and
M, respectively in (6). A double stage concept of DMAS, it
is adapted from ultrasound imaging [64], [65] to solve the
the data and enhance detection accuracy. To do so, the left problems of low resolution and sensitivity of DAS and DMAS
and right knees are scanned by a 12-element antenna array, algorithms in addition to its capability to detect small and deep
and data are recorded in two matrices. To emulate the natural targets with high contrast compared to single-stage DMAS
mirror-orientation of left/right knees, one of the two matrices is [64], [65], it can be expressed as follows:
mirrored before being subtracted from the other matrix:

M −2 M
 −1
E(t) = Xi (t)Xj (t)
Sm (τ ) = VU (t) − V H (t) (4) i=1 j=i+1

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530 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO. 3, JUNE 2021

Fig. 17. Block diagram of the proposed imaging algorithm that combines double multiply stage and coherence factor to improve the reconstructing images.

= X1 (t)[X2 (t) + X3 (t) + · · · + XM −1 (t)]


+ X2 (t)[X3 (t) + X4 (t) + · · · + XM −1 (t)]
+ ···
+ XM −2 (t)[XM −1 (t)]

M −2
× Dk (t) (8)
k=1
Fig. 18. (a) Configuration of the proposed system in the simulation environ-
ment (a)3-D structure, (b) transverse view, and (c) transverse slice of the knee
where Dk (t) and E(t) refer to the term number k in (5) and the joint.
output signal of DS-DMAS, respectively. On the other hand,
the coherence performance of the scattered signals is taken into
consideration to improve the coherence quality of the received B. Numerical Verification of Brace System
signal [29]. The calculated coherence factor is applied to the Since the contrast between the dielectric properties of the fluid
final output signal that can be calculated as: that accumulate after tear and surrounding tissues (muscle and
bones) is high (see Fig. 3), the differential scan is helpful to
 M 2 detect ligament tear. Fig. 18 shows the numerical setup of the
M −1
i=1 j=i+1 Si (t) Sj (t) proposed brace system in presence of a realistic knee model in
CF (t) = M −1 M (9)
i=1 j=i+1 |Si (t) Sj (t)|2 the CST microwave studio. For the injured knee, different targets
of volumes (2.25 to 8 mL) representing the accumulated fluid are
ECF (t) = CF (t) E (t) (10) inserted inside the knee model to emulate different knee injuries
as listed in Table III. Fig. 19 presents the reconstructed images
where CF is the coherence factor and E refers to the output signal; using the delay and sum (DAS) and proposed algorithms. The
that represents the intensity of the signal at each focal point. higher intensity (red color) indicates the detected position of

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 531

TABLE III
COMPARISON BETWEEN DAS, DMAS AND DS-DMAS FOR DIFFERENT SCENARIOS

dc refers to delocalization between centers in cm.

Fig. 19. Reconstructed images from different simulated scenarios of knee


injuries. Cases (1-2) represent LCL tear, (3-4) MCL tear, (5-6) tendon tear, and
(7-8) ACL/PCL tear.

the targets, whereas the circles and squares indicate the exact Fig. 20. DS-DMAS reconstructed images for healthy (H-H) and unhealthy
knees for left/right knee asymmetry and left/right brace misalignment.
location of cylindrical and cubic targets, respectively. In con-
trast, the dark blue indicates high similarity between left/right
knee tissue, indicating healthy tissues. The reconstructed images
demonstrate that the tear location and its approximate size are different healthy knee tissues have close values of dielectric
successfully detected using the proposed method compared with properties, Fig. 3(a)–(c), compared to the high contrast caused
significant errors or false targets when using other methods. by knee injuries. On the other hand, to study the impact of any
To investigate the impact of displacement (uncertainty in slight difference between the anatomical structure of the left and
positioning) of the brace, vertical and angular displacements are right knee, the cases #3 and #7 are repeated with relatively large
studied as Δz and ΔΦ, respectively (see Fig. 18 for the directions +5% differences in the dielectric properties of all tissues in the
of those displacements), on cases #(1, 3, 5, 7). The created healthy knee compared to their counterpart tissues in the injured
images (Fig. 20 ) show that the system is robust to displacements knee. The reconstructed images in Fig. 20 confirm robustness of
of ∼10 mm and angular rotation of 10o thanks to the fact that the system to those differences.

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TABLE IV
ROBUSTNESS OF DS-DMAS WITH LEFT/RIGHT ASYMMETRY AND MISALIGNMENT

Fig. 22. A sample of measured S-parameters when antenna array attached on


the homogeneous knee phantom. (a) reflection coefficients and (b) transmission
coefficient between neighboring antennas.

Fig. 21. Setup of brace system; it consists of 12-element antenna array attached
to homogeneous knee phantom that connected to multiport VNA via RF cables
and PC to analyze the recorded data.

To assess quality of the generated images using the proposed


method compared to DAS and DMAS, three quantitative factors
are used [29], [56]: the first factor is the contrast ratio index CR
which refers to the mean intensity of the target region compared
to the surrounding background clutter in the reset of the knee
domain. The second factor dc is the displacement between the
center of the detected target (Cd ) region and the actual target
region in the simulated or measured environment (Ca ). The third Fig. 23. Photos of the targets that used during the measurements to emulate
knee injuries; Tm1 : a cubic of 3 × 1.5 × 5 cm3 , Tm2 : a cubic of 3 × 2.5 ×
factor is the maximum intensity ratio M IR, which refers to 5 cm3 , and Tm3 : a cylinder of 0.75 cm radius and 6 cm length.
the maximum intensity of the target (It ) region compared to
the corresponding same region of healthy-to-healthy differential
image (Ih ). MIR is used to differentiate between the healthy
cases and unhealthy cases [56]. dc = |Cd − Ca | (12)
max (It )
CR =
μt M IR = (13)
μb
(11) max (Ih )

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SULTAN et al.: TEXTILE ELECTROMAGNETIC BRACE FOR KNEE IMAGING 533

TABLE V
COMPARISON BETWEEN DIFFERENT SCENARIOS OF KNEE INJURIES BASED ON
EMBEDDED TARGET INSIDE KNEE PHANTOM

∗ CR1 and CR2 are contrast ratios after the first and second stage, respectively. A refers
to the order of antenna.

Fig. 25. Photos for some steps for unhealthy knee phantom (right knee) (a)
The integration between tibia bone and connective tissues, (b) The integration
between femur bone, muscle, target, and tibia with connective tissue, (c) The
whole 3-D unhealthy phantom after fat and skin layers, and (d) Configuration
of proposed brace system with durable knee phantom.

Those quantitive factors are calculated for the reconstructed


images in Fig. 19 and listed in Table III, which confirms superi-
ority of the proposed DS-DMAS in detecting different targets.
Also, the reconstructed images in Fig. 20 are evaluated with
the aforementioned three quantitively factors and the results are
listed in Table IV. The values of CR and dc along with the high
values of MRI prove that the impact of those slight left/right
displacements and asymmetry are negligible compared to the
high contrast between the dielectric properties of accumulated
fluid after ligament tear and surrounding tissues.

C. Brace Verification on Homogeneous Knee Phantom


The brace is used to image a knee phantom, which is filled with
homogeneous liquid (see Section III-C). The liquid phantom was
utilized to study different sizes/locations of ligament tears that
cannot be done with rigid realistic phantoms. The embedded
antenna elements in the brace are connected to a multiport
VNA (Keysight M9037A). The system is calibrated using the
electronic calibration tool (Keysight-859xC) over the frequency
band from 0.5-2.5 GHz. Firstly, the measurements of the healthy
phantom are done and the backscattered signals are captured (see
Fig. 22). Secondly, several measurements are performed when
a target is embedded inside the homogeneous knee phantom to
emulate ligament tear at different positions. Fig. 23 illustrates
photos of different sizes and shapes of the used targets. Table
V shows the different scenarios that are carried out during the
Fig. 24. Reconstructed images of different targets with different sizes and at measurements. To simplify the positioning of the target inside
different positions to emulate different cases of ligament/tendon tears.
the liquid, for LCL, MCL, and tendon cases, the targets are

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534 IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 15, NO. 3, JUNE 2021

phantoms, which represents a healthy knee, is the same one


that was presented recently by the authors in [55] whilst the
other one represents an unhealthy knee with ACL/PCL tear that
was fabricated with the same procedure in [55] as shown in
Fig. 25(a-c). To emulate the Haematoma fluid deposition after
a ligament tear, distilled water was used because accumulating
fluid after ligament injury is mainly water [2], [50]. A polylactic
acid (PLA) target container was manufactured as a hollow sphere
of 0.25 mm wall thickness and 10 mm radius and filled with
approximately 4 mL of distilled water. The target is embedded
inside the phantom during the fabrication process in the position
of ACL/PCL tear, which is a common and serious knee injury
(see Fig. 25(c)).
A photograph of the experimental setup is shown in Fig. 25(d).
The healthy and unhealthy phantoms were scanned sequentially,
4 times to ensure the reliability of measurements. The measured
S-parameters of the proposed antenna array in presence of the
unhealthy durable knee phantom are shown in Fig. 26(a) and
(b). The reconstructed image in the case of the durable phantom
(see Fig. 26(c)) has a high contrast at the target location with a
contrast ratio of 11.79 compared to the healthy tissues. On the
other hand, the detected target has a slight shift of dc = 0.45 cm
from the actual position of the target.

V. CONCLUSION
A wearable electromagnetic brace imaging system for the
early detection of knee connective tissues’ tear onsite has been
introduced. The brace is comprised of a twelve-element antenna
array that is knee matched to achieve compact size and improved
penetration. The unidirectional antenna utilizes a dual-slot loop
and matched stubs and is fabricated on textile wool felt ma-
terial to achieve wide operational bandwidth and conformity
with knee curvature. The brace is evaluated numerically and
experimentally on realistic phantoms with different types and
Fig. 26. Results of the brace system in presence of durable phantom. (a-b) stages of ligaments/tendon tear. A modified double stage DMAS
Measured S-parameters of the antenna array in presence of durable phantom.
(c) The reconstructed image in case of ACL/PCL tear in durable phantom. combined with coherence factor and differential left/right knee
imaging is used to reconstruct knee images in different sce-
fixed close to the edge of the phantom, while the multi-section narios of ligament and tendon tears. The reconstructed images
holder (see Fig. 15(d)) is used to fix the targets in case of ACL/ demonstrate brace capability of detecting shallow and deep knee
PCL. The presented algorithm is then used to produce knee injuries at early stages as it can detect accumulated fluid of
images as presented in Fig. 24. It is clear that the targets are 1.3 mL at the location of ACL/PCL and 1.1 mL at the loca-
detected and localized with significant contrast compared to the tion of MCL/LCL/Tendon which are less than the accumulated
surrounding knee medium. The calculated metrics confirm the fluid in the first grade of ligaments tear. The proposed portable
ability of the modified algorithm to detect all targets with high electromagnetic brace can be used at home, sports fields, and
contrast compared to a single-stage DMAS as listed in Table V. clinics, making it easy to detect and manage early injuries and
The system not only has the ability to detect shallow tears, but avoid serious consequences. Since it is wearable, it can be used
it has also the ability to detect deeper targets like cases 7 and 8 for knee monitoring.
(see Table V).
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evaluation with post-biopsy marker,” IEEE J. Electromagn., RF Microw. University of Sydney, Sydney, NSW, Australia. He is
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Frequency Electromagnetic Fields, 3 kHz to 300 GHz, IEEE Standard lications on the topics of meniscus transplantation,
C95.1, Apr. 1999. anterior cruciate reconstruction and electromagnetic
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crowave imaging of the breast pair,” IEEE Antennas Wireless Propag. Lett., from The University of Queensland, Brisbane, QLD,
vol. 15, pp. 1434–1437, Dec. 2015. Australia, in 2013, as recognition of the international
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crowave imaging for breast cancer detection: Delay-multiply-and-sum magnetic Innovations Group and the Head of School
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and sum beamforming algorithm in ultrasound B-mode medical imaging,” devices, and planar antennas. He won IEEE APS King
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