SCORE:

NAME: _____________________________________________
MATRIC NUMBER: ___________________________________
CLASS: ____________________________________________ /121

POST TEST: 4.2 DEVIATIONS FROM MENDELIAN INHERITANCE

PART A: MULTIPLE CHOICE QUESTIONS

1. What are the possible phenotypes of the children if the mother's genotype is ii for blood
type and the father is IAIB?
A. all AB C. 1/2 A: 1/2 AB
B. 1/2 A: 1/2 B D. 1/2 A: 1/4 B: 1/4 AB

2. What are the predicted genotypes of the female child from the union of a woman who is
heterozygous for hemophilia and a man who is normal blood clotting characteristics?
A. XHXH or XHXh C. XHYH
H h
B. X X D. Hh

PART B: STRUCTURED QUESTIONS.

3 Fur colour in the Canadian Bigfoot is controlled by three alleles Cb, Cr and c.
(c is recessive). A black-coated male mated with a red-coated female over a number of
years, producing a family of ten offspring; 2 black, 3 reds, 2 chestnuts (a mixture of black
and red hairs) and 3 white.

a) What term would you use to describe the alleles Cb and Cr? [1 mark]

___________________________________________________________________

b) What is the genotype of the white-coated offspring? [1 mark]

___________________________________________________________________

c) What are the genotypes of the two parents? [1 mark]

___________________________________________________________________

d) What ratio would you have predicted for the four phenotypes listed above? [1 mark]

___________________________________________________________________

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 e) What phenotype would you expect from the crossing of chest-nut coated and white
coated bigfoot? [2 marks]

___________________________________________________________________

f) If two chestnut coated bigfoot mated, what would the probability be of their first baby
also being Chestnut coated? Explain your answer using a genetic diagram.
[3 marks]

4. A cross was made between homozygous brown eyed female dog and blue eyed male
dog. The offspring (F1) generation all had brown eyed. Two progeny from F1 were
crossed and
the numbers of resulting phenotypes were counted. The results are shown below:

Phenotypes of F2 Number of male Number of female

Brown eyed 425 420
Blue eyed 142 139

(a) (i) What is the recessive trait for the eye colour of dog? Why?

________________________________________________________________
[2 marks]

(ii) From this result, can you determine whether the eye colour of dog was sex-linked
gene? Explain your answer.
________________________________________________________________

________________________________________________________________

________________________________________________________________
[3 marks]

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 (iii) Using suitable symbols draw a genetic diagram to show the frequencies of all
possible genotypes and phenotypes of this cross.

[4 marks]

(a) A cross was made between the progeny of F2 and the result shows 50% of the offspring
were blue eyed. From this cross, what are the possible genotypes of these individual:

I. Parent 1 (F2): _____________________________________________

II. Parent 2 (F2): _____________________________________________

III. Progeny (F3): _____________________________________________

[3 marks]

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2. The shapes and colours in carrots are determined by two pairs of different alleles. Both
pairs of alleles did not show dominancy. Each genotype produces different phenotypes.
Colours of carrot are red (CRCR), purple (CRCW) or white (CWCW). The shapes are long
(SLSL), oval (SLSN) or round (SNSN).

(a) What type of inheritance is shown by the shape and colours of carrot?

____________________________________________________ [1 mark]

(b) (i) The long, red carrot is crossed with the round, white carrot. With a genetic
diagram, show the parent genotypes, gametes and F1 generation.

[3 marks]

(ii) If the F1 generation is self-crossed, what are the frequencies for the following
phenotypes?

Phenotypes Frequency
Red, oval
Purple, long
White, long
White, round
[4 marks]
(c) If the purple, oval carrot has the highest demand in the market, give TWO
possible crosses that can be done to meet the demand.
[2 marks]
_______________________________________________________________

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3. In Drosophila, dominant G allele produces wild Drosophila which is grey body. The
recessive g allele produces yellow body. Draw the genetic diagram for the above
crossing. [3 marks]

i. What percentage of the F1 progeny is expected to be homozygous?

____________________________________________________ [1 mark]

ii. Among the male progenies, what percentage is expected to be yellow bodied?

____________________________________________________ [1 mark]

4. A woman with group A blood marries a man with group B blood. Their child has group
O blood.

(i) What is meant by multiple allele?

__________________________________________________________

__________________________________________________________
[1 mark]
(ii) State the genotypes for the:

woman: __________________________________________________

man : __________________________________________________

child : __________________________________________________
[3 marks]

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5. FIGURE 1 shows a family tree for the inheritance of ABO blood groups involving
multiple alleles. Blood groups for some individuals are labeled.

I O
1 2

O B A
II
3 5
4

III B
6 7 8
Key: Male Female
FIGURE 1

(a) What is meant by multiple alleles?

________________________________________________________________

________________________________________________________________
[2 marks]

(b) List all possible combinations of alleles for ABO blood groups.

________________________________________________________________

________________________________________________________________
[2 marks]

(c) List all genotypes of individuals with B blood group.

________________________________________________________________
[1 mark]

(d) What is the blood group for individual I-2?

________________________________________________________________
[1 mark]

(e) Give the genotype of individual II-5?

________________________________________________________________
[1 mark]

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 (f) Using a Punnet square, give the probability of the offspring of individuals II-4 and
II-5 having blood group O. [3 marks]

6. FIGURE 1 shows pedigrees A and B with specific disorder.

FIGURE 1

(a) (i) Which pedigree shows the disorder most likely inherited by an X-linked
recessive allele?

________________________________________________________________
[1 mark]
(ii) Give ONE reason for your answer.

________________________________________________________________
[1 mark]

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(b) Assuming that the disorder is due to allele r, draw the genetic cross between
parents 1 and 2 of your chosen pedigree.

[3 marks]

(c) Using the symbol D as a dominant allele and d as a recessive, state the
genotype of parents 1 and 2, and the affected daughter in pedigree B.

Parent 1 : ______________________________________________

Parent 2 : ______________________________________________

Affected daughter : ______________________________________________

[3 marks]

(d) What is the ratio of heterozygous genotype in F1 generation of pedigree B?

________________________________________________________________
[1 mark]

(e) Give ONE example of the disorder of each pedigree.

Pedigree A: _____________________________________________________

Pedigree B: ______________________________________________________
[2 marks]

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7. FIGURE 1 shows a pedigree of blood groups for one family.

FIGURE 1

(a) Using symbols IA, IB, and i to represent the alleles involved, write the genotypes
of the following individuals

I-1 : ___________________________________________________________

II-2 : ____________________________________________________________

III-3 : ____________________________________________________________
[3 marks]

(b) State the possible blood group of individual III-3. Give TWO reasons.

________________________________________________________________

________________________________________________________________

________________________________________________________________
[3 marks]

(c) What are the genetic basis that produce the four blood groups in human?

________________________________________________________________

________________________________________________________________
[2 marks]

(d) If individual III-3 marries a man with blood group O, what are the possible blood
groups of their children?

________________________________________________________________

________________________________________________________________
[2 marks]

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8. Haemophilia A is an inherited X-linked recessive disorder that prevents blood clotting.

(i) Define X-linked recessive inheritance.

[2 marks]
___________________________________________________________

___________________________________________________________

(ii) Mary, a haemophilia carrier, marries John, who has a normal X

chromosome. Using suitable symbols, draw a Punnet square to show the
possible genotypes and phenotypes of their offspring including the ratio of
haemophilic offspring.
[5 marks]

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PART C: ESSAYS QUESTIONS.

9. Explain polygenic inheritance. [8 marks]

10. With the aid of genetic diagram, explain incomplete dominance and its inheritance in
snapdragon (Antirrhinum sp.) [12 marks]

11. A man with AB blood group marries a woman with B blood group. The couple has three
boys and one girl with different types of blood group. With the aid of a genetic diagram,
describe the crossing.
[10 marks]

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