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Jaime Valle-Leal2 Dr. Jaime Valle Leal
valle_jaime1@hotmail.com
Abstract
)(*2.96<5+!9LSH[PVUZOPWVM[V[HSZLY\T0N,HUKHSSLYN`OHZILLU ƐƚĞĂƌơĐƵůŽĚĞďĞĐŝƚĂƌƐĞĐŽŵŽ
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Valle-Leal J. Inmunoglobulina E total como marcador
6)1,*;0=,!;V KL[LYTPUL ^OL[OLY ZLY\T [V[HS 0N, PZ H \ZLM\S [VVS de alergia en el noroeste de México. Rev Alerg Méx.
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,Z[L LZ[\KPV PUJS\`} ZxU[VTHZ YLZWPYH[VYPVZ
J\[mULVZ ` NHZ[YVPU[LZ[PUHSLZ 3VZ OHSSHaNVZ
KLT\LZ[YHU TH`VY WYL]HSLUJPH KL ZxU[VTHZ
YLZWPYH[VYPVZ3HKPZLTPUHJP}UKLSVZHSLYNLUVZ
HS
:L NLULY} \UH J\Y]H 96* WHYH KL[LYTPUHY SH
ZLUZPIPSPKHK`LZWLJPÄJPKHKKLSH0N,[V[HSJVU
SHÄUHSPKHKKLLUJVU[YHYLSTLQVYW\U[VKLJVY[L
X\L KPZJYPTPUL LS KPHNU}Z[PJV KL LUMLYTLKHK
WVY]xHHtYLHLZTmZHTWSPH`WLYZPZ[LU[LSVX\L
L_WSPJH Z\ TH`VY WYL]HSLUJPH3 SVZ KLTmZ ZVU
TLUVZ MYLJ\LU[LZ WLYV KL THUPMLZ[HJP}U TmZ
PUZPKPVZH`Z\KPHNU}Z[PJVLZWVYL_JS\ZP}U
,S]HSVYKLYLMLYLUJPHLZ[HISLJPKVWHYH0N,[V[HS
HStYNPJH 3H JVTIPUHJP}U TmZ HS[H KL ZLUZPIP- WYVWVYJPVUH ZLUZPIPSPKHK KL  KL[LJ[H SHZ
SPKHK ` LZWLJPÄJPKHK ZL VIZLY]} JVU \U JVY[L WVZPISLZ ZLUZPIPSPKHKLZ OHJPH HSLYNLUVZ" HZP-
KL<0,UJ\Y]H96*mYLHIHQVSHJ\Y]HKL TPZTV SH LZWLJPÄJPKHK KPHNU}Z[PJH JHSJ\SHKH
JVU0*  -PN\YH LULZ[LLZ[\KPVM\LKL[HUZ}SVSVX\LLZ
ZPNUPÄJH[P]HTLU[LIHQV`WHYLJPLYHPUKPJHYX\L
DISCUSIÓN SH\[PSPaHJP}UKLSH0N,ZtYPJH[V[HSWVYZxTPZTH
UVLZLZWLJxÄJHLUHWYV_PTHKHTLU[LKL
+LIPKVHSHZJHYHJ[LYxZ[PJHZNLVNYmÄJHZ`JSPTH- los casos.
[VS}NPJHZWHY[PJ\SHYLZKLSUVYVLZ[LKL4t_PJV
tZ[L [PLUL NYHU KP]LYZPKHK KL HSLYNLUVZ X\L 3H0N,[PLULHS[HZLUZPIPSPKHKWHYHKL[LJ[HYZLU-
ZPIPSPaHJP}UHHLYVHSLYNLUVZLUU\LZ[YVTLKPV"
LZ[VZOHSSHaNVZHWV`HUSVLUJVU[YHKVWVY;SHJOP
*VYVUH`Z\NY\WVLU3
Curva ROC
1.0
,SNY\WVL[HYPVJVUTH`VYLSL]HJP}UKL0N,M\L
0.8 LSKLLZJVSHYLZJVUJVUJLU[YHJPVULZTH`VYLZKL
<0T3KLIPKVHSHL_WVZPJP}U`ZLUZPIPSPaH-
Susceptibilidad

0.6 JP}UHHSLYNLUVZ*VUIHZLLUU\LZ[YVLZ[\KPV
ZLKLÄULLS]HSVYKLYLMLYLUJPHKLSHZJVUJLU[YH-
0.4 JPVULZKL0N,[V[HSLUSVZUP|VZKLSUVYVLZ[LKL
4t_PJVX\LLZPUKLWLUKPLU[LKLSZL_V`KLSH
0.2 LKHK"LZ[VZOHSSHaNVZHWV`HUSHJVUJLU[YHJP}U
KL0N,WHYHKPZJYPTPUHYUP|VZJVULUMLYTLKHK
0.0 HStYNPJH`ZPUHSLYNPHJVU\UW\U[V}W[PTVKL
0.0 0.2 0.4 0.6 0.8 1.0 JVY[LKL<0LSKVISLKLSVYLWVY[HKVWVY;\
Especificidad
en 2013LUWVISHJP}UHZPm[PJH<0

-PN\YH*\Y]HKL96*KLSHLMLJ[P]PKHKKL0N,ZtYPJH *VU JVUJLU[YHJPVULZ LSL]HKHZ KL 0N, SH WVZP-

[V[HS JVTV WY\LIH KL [HTPaHQL WHYH WHJPLU[LZ JVU IPSPKHK KL [LULY WY\LIHZ J\[mULHZ WVZP[P]HZ ZL
ZVZWLJOHKLHSLYNPHZ PUJYLTLU[H`WVYLSJVU[YHYPVJVUJVUJLU[YHJPV-

24

Ramírez-Enríquez F y col. IgE: marcador de alergia en el noroeste de México
ULZIHQHZKLPUT\UVNSVI\SPUH,SHWYVIHIPSPKHK
KLYLZ\S[HKVZULNH[P]VZLZTH`VY
,Z[L LZ[\KPV WYVWVYJPVUH PUMVYTHJP}U ]HSPVZH
HJLYJHKLSVZWH[YVULZKLZLUZPIPSPaHJP}U"ZPU
LTIHYNV ZL ULJLZP[HU TmZ PU]LZ[PNHJPVULZ
HS YLZWLJ[V WHYH JVTWYLUKLY SHZ JVTWSLQHZ
YLSHJPVULZ LU[YL SHZ L_WVZPJPVULZ H HSLYNLUVZ
`SHHWHYPJP}UKLSHZLUZPIPSPaHJP}UHStYNPJH`
SHLUMLYTLKHK
3H0N,LULSTLKPVOVZWP[HSHYPVJVU[PU‚HZPLUKV
\UTt[VKV‚[PSKLLZJY\[PUPVWHYHSVZWHJPLU[LZ
JVUZxU[VTHZYLZWPYH[VYPVZJY}UPJVZWLYVUVLZ
KLÄUP[P]H WVYX\L Z\ LZWLJPÄJPKHK LZ IHQH :PU
LTIHYNV JVTV WY\LIH WHYH YLHSPaHY [HTPaHQL
LZ‚[PSZPZLJ\LU[HJVULSSH"LSJVZ[VLZIHQV`
VYPLU[HOHJPHSH[VTHKLKLJPZPVULZ`KLYP]HJP}U
oportuna.
(SN\UHZSPTP[HU[LZKLLZ[LLZ[\KPVM\LYVULSHJV-
WPVKLKH[VZKLTHULYHYL[YVZWLJ[P]HX\LSPTP[H
L_WSVYHYV[YVZWVZPISLZYLZ\S[HKVZHSJVUZPKLYHY
V[YVZMHJ[VYLZJVTVtWVJHKLSH|VLUX\LZL
TPKHSH0N,`ZLYLHSPJLUSHZWY\LIHZJ\[mULHZHZx
JVTVSHJSHZPÄJHJP}UHTIPN\HKLSVZZxU[VTHZ
respiratorios.
CONCLUSIÓN
3H WY\LIH KL 0N, [V[HS LU WSHZTH LZ \UH OL-
YYHTPLU[H ‚[PS KL [HTPaHQL PUPJPHS LU WHJPLU[LZ
JVUZVZWLJOHKLHSLYNPHJ\HUKVZ\ZZxU[VTHZ
principales son respiratorios; la asociación entre
WY\LIHZ J\[mULHZ WVZP[P]HZ ` JVUJLU[YHJPVULZ
LSL]HKHZKL0N,[\]VZPNUPÄJHJP}ULZ[HKxZ[PJH
Re vista
Mé xic o
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ĞŶ͗ ŚƩƉ͗ͬͬĂĐ͘ĞůƐͲĐĚŶ͘ĐŽŵͬ^ϬϬϵϭϲϳϰϵϭϰϬϭϱϳϱϵͬϭͲƐϮ͘ϬͲ
^ϬϬϵϭϲϳϰϵϭϰϬϭϱϳϱϵͲŵĂŝŶ͘ƉĚĨ͍ͺƟĚсĨϱϰϱϯϲϲϰͲĨϱϵĞͲϭϭĞϰͲ
ϴϬϬϰͲϬϬϬϬϬĂĂĐďϯϲϮΘĂĐĚŶĂƚсϭϰϯϭϭϬϮϱϱϵͺϯďϳϮϳϳϲϯĂϴϮ
ϭĩϴĨϴϲĚĚϭĂĞĂĞĚϰϲϲϰĞĞ
6. >ĞǀŝŶD͕DĂƚŚŝĂƐZ͕,ƵĂŶŐ>͕ZŽƚŚ>͕ĞƚĂů͘ŵĞƚĂͲ
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/ŐŝŶĚŝǀĞƌƐĞƐƚƵĚLJƉŽƉƵůĂƟŽŶƐ͘:ůůĞƌŐLJůŝŶ/ŵŵƵŶŽů͘
΀ŝŶƚĞƌŶĞƚ΁͘ ϮϬϭϯ͖ϭϯϭ͗ϭϭϳϲͲϭϭϴϰ͘ ŝƐƉŽŶŝďůĞ ĞŶ͗ ŚƩƉ͗ͬͬ
ǁǁǁ͘ŶĐďŝ͘Ŷůŵ͘ŶŝŚ͘ŐŽǀͬƉŵĐͬĂƌƟĐůĞƐͬWDϯϱϵϲϰϵϳ͘
7. Dŝƌ͕WĂŶũĂďŝ͕^ŚĂŚ͘/ŵƉĂĐƚŽĨĂůůĞƌŐŝĐƌŚŝŶŝƟƐŝŶƐĐŚŽŽů
ŐŽŝŶŐĐŚŝůĚƌĞŶ͘ƐŝĂWĂĐůůĞƌŐLJϮϬϭϮ͖Ϯ͗ϵϯͲϭϬϬ͘ŝƐƉŽŶŝďůĞ
ĞŶ͗ŚƩƉ͗ͬͬĂƉĂůůĞƌŐLJ͘ŽƌŐͬ^LJŶĂƉƐĞͬĂƚĂͬW&ĂƚĂͬϵϵϵϲWͬ
ĂƉĂͲϮͲϵϯ͘ƉĚĨ
8. dƵz>͕ŚĂŶŐ^t͕dƐĂŝ,:͕ŚĞŶ>͕ĞƚĂů͘dŽƚĂůƐĞƌƵŵ/Ő
ŝŶĂƉŽƉƵůĂƟŽŶͲďĂƐĞĚƐƚƵĚLJŽĨƐŝĂŶĐŚŝůĚƌĞŶŝŶdĂŝǁĂŶ͗
reference value and significance in the diagnosis of
ĂůůĞƌŐLJ͘ W>Ž^ KE͘ ϮϬϭϯ ϴ;ϭϭͿ͗ ΀ĞϴϬϵϵϲ͘΁ ŽŶƐƵůƚĂĚŽ ĞŶ
ŐŽƐƚŽĚĞϮϬϭϱ͘ŝƐƉŽŶŝďůĞĞŶ͗ŚƩƉ͗ͬͬǁǁǁ͘ƉůŽƐŽŶĞ͘ŽƌŐͬ
ĂƌƟĐůĞͬĨĞƚĐŚKďũĞĐƚ͘ĂĐƟŽŶ͍ƵƌŝсŝŶĨŽ͗ĚŽŝͬϭϬ͘ϭϯϳϭͬũŽƵƌŶĂů͘
ƉŽŶĞ͘ϬϬϴϬϵϵϲΘƌĞƉƌĞƐĞŶƚĂƟŽŶсW&
25