Tranexamic acid

Cyklokapron
CLASSIFICATION(S)
Therapeutic: hemostatic agents; Pharmacologic: antifibrinolytics , plasminogen inactivators
INDICATIONS
•Prevention or reduction of hemorrhage following dental surgery in hemophiliacs
ACTION

•Inhibits activation of plasminogen, thereby preventing the conversion of plasminogen to plasmin

•Therapeutic Effects:
○Decreased bleeding following dental surgery in hemophiliacs
○Reduced need for replacement therapy
CONTRAINDICATIONS/PRECAUTIONS
•Hypersensitivity
•Active intravascular clotting
•Acquired defective color vision
•Subarachnoid hemorrhage

ADVERSE REACTIONS/SIDE EFFECTS*

CNS: dizziness; EENT: visual abnormalities,CV: hypotension, thromboembolism, thrombosis, GI: diarrhea,
nausea, vomiting,
AVAILABILITY
•Tablets: 500 mg
•Solution for injection: 100 mg/ml in 5-ml ampules, 100 mg/ml in 10-ml ampules

NURSING IMPLICATIONS

•Instruct patient to take tranexamic acid as directed. Do not take more or less than directed. If a dose is missed,
take as soon as possible unless almost time for next dose; do not double doses
•Advise patient to inform health care professional of any changes in vision. Inform patients on prolonged
therapy of the importance of regular ophthalmologic follow-up
•Caution patient to avoid products containing aspirin or NSAIDs without consulting health care professional
•Instruct patient to notify health care professional if signs and symptoms of thrombosis (severe, sudden
headache; pains in chest, groin, or legs, especially calves; sudden loss of coordination; sudden and unexplained
shortness of breath; slurred speech; visual changes; weakness or numbness in arm or leg) occur