Professional Documents
Culture Documents
A Case Study on
Bacterial Pneumonia
Submitted to:
Sebastian, Aljessa RN, RTRP
Submitted by:
Aguinaldo, Precilda G.
Bermudez, Celine Mickaela A.
Carumba, Rica Hannah
Dilangalen, Alezandra
Eliseo, Jamielle F.
Labrador, Gabrielle
Salandron, Jennie Vil E.
Samad, Hanna Lalaine
Santos, Noriel AJ G.
Tabangan, Romeo
July 2021
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TABLE OF CONTENTS
X. Pathophysiology
a. Factors ………………………………………………………………. 19-23
b. Diagram ……………………………………………………………… 24-29
c. Narrative ……………………………………………………………… 30
XI. Medical Management ………………………………………………………. 31-34
XII. Drug Study ……………………………………………………………………. 35-68
XIII. Respiratory Therapy Care Plan …………………………………………….. 69-71
XIV. Pulmonary Rehabilitation ……………………………………………………. 72-74
XV. Prognosis ……………………………………………………………………… 75
References ……………………………………………………………………………. 76-78
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INTRODUCTION
Pneumonia is an inflammation that causes the air sacs of one or both lungs to
become filled with fluid or pus. The infection manifests cough with phlegm or pus, fever,
chills, and difficulty breathing. It is caused by invasive microorganisms such as bacteria,
fungi, or viruses.This infection can be a life-threatening disease. For infants and young
children, 65 years old and above, and those who have weak or problems with their
immune system pose a serious effect of the infection (Mayo Foundation for Medical
Education and Research, 2021).
According to the Centers of Disease and Prevention, more children younger than
5 years old are killed by this infectious disease of the lungs called pneumonia than any
other disease such as tuberculosis, malaria, and HIV infection. In the United States,
during 2017 there were around 1.3 million people who were diagnosed with pneumonia
in an emergency department. Lower respiratory tract infections regard for more
morbidity and mortality compared to other infections. Additionally, there are more than 5
million CAP incidence in the United States per year; 80% are treated as outpatients with
less than 1% of mortality rate, whereas inpatients account for 20% with a mortality rate
of 12% to 40% ( Sattar & Sharma, 2021). On the other hand, pneumonia in the
Philippines is one of the leading causes of deaths among Filipinos. According to the
World Health Organization (WHO), 75, 970 or 12.27 % fatalities were recorded in
pneumonia deaths along with the flu. In 2016, the Philippines reported 57,809
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pneumonia deaths, almost 10 percent of the registered deaths during that year. Due to
pneumonia prevalence, it became the third top killer behind ischemic heart disease and
cancer (Outbreak News Today, 2017). In 2018, pneumonia caused about 56.8 thousand
deaths and was the 3rd leading cause of death among Filipino women ( Statista, 2021).
Pneumonia has been one of the major contributing factors of death around the
world. This disease is also prevalent in the Philippines which makes it become one the
top killers in the said country . In 2016, the Philippines recorded a 786,085 number of
pneumonia cases with a rate of 758 cases per 100,000 population.
The 2016 Philippine health statistics recorded 50,040 pneumonia cases in Davao
Region with a rate of 994 cases per 100,000 of the population (Epidemiology Bureau
Department of Health, n.d.). The case study is conducted in order to provide knowledge,
prevention, and management of the disease. This is beneficial in the Respiratory
therapy field and in the areas where pneumonia is more prevalent.
GENERAL OBJECTIVES
At the end of our General Respiratory Care rotation, we, as BSRT 4 interns
would be able to produce a detailed case study to be utilized and be a source of
supplementary knowledge on the emergence and even management of patients with
pneumonia to be able to improve the practice of our profession.
SPECIFIC OBJECTIVES
Specifically, we intend to:
a. Exhibit an introduction that states relevant global, international, and national
topics related to the purpose of this study with regards to our focused subject,
pneumonia,
b. identify the study’s association to the RT study, research, and practice,
c. draw smart objectives as a guide in the completion of this study,
d. describe the medical diagnosis,
e. indicate the patient’s past and present medical and/or health history,
f. assess the patient in cephalocaudal manner giving emphasis to the abnormalities
observed related to their case, pneumonia,
g. review the anatomy and physiology of the affected system,
h. detect the pathophysiology of the diagnosis to be presented in a diagram with a
stated narrative,
i. list the actual and possible diagnostic tests that helped come up with the
diagnosis,
j. link the laboratory results to the patient’s condition,
k. acknowledge the importance of medical management done to the patient,
l. talk over the drugs administered to or by the patient by presenting its indications;
side and adverse effects, mode of action, and the appropriate respiratory
interventions,
m. come up with respiratory care plans considering the immediate needs of the
patient, and
n. describe the prognosis of the patient’s condition after being rendered relevant
interventions.
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DEFINITION OF DIAGNOSIS
The word pneumonia comes from the ancient Greek word “pneumon”, which
means “lung”, therefore, the word pneumonia becomes a disease of the lungs (Sattar &
Sharma, 2021). Pneumonia is the inflammation of the tissue in one or both lungs which
is usually caused by a bacterial infection (NHS Choices, 2019). On the other hand, this
disease is a common acute respiratory infection that damages the distal airways and
alveoli which is considered as a major health problem that is associated with high
morbidity in all age groups worldwide (Torres, A., Cilloniz, C., Niederman, M.S. et al.,
2021).
A huge variety of microbial organisms can cause pneumonia with great
geographical variations in their prevalence such as bacteria, fungi, and viruses.
Bacterial pneumonia is caused by a pathogenic infection of the lungs. The most
consistent presenting symptom of bacterial pneumonia is cough productive of sputum
(Gamache, 2021).
According to the American Lung Association, bacterial pneumonia can occur on
its own or develop after you've had a viral cold or the flu. Bacterial pneumonia often
affects just one part, or lobe, of a lung. Those at greatest risk for bacterial pneumonia
include people recovering from surgery, people with respiratory disease or viral infection
and people who have weakened immune systems. There are many types of
pneumonia, and the most common type of bacterial pneumonia is called pneumococcal
pneumonia. Pneumococcal pneumonia is caused by bacteria that live in the upper
respiratory tract. Common symptoms of pneumococcal pneumonia include high fever,
excessive sweating and shaking chills, coughing, difficulty breathing, shortness of
breath and chest pain. Certain symptoms, such as cough and fatigue, can appear
without warning and may last for weeks, or longer. If you're 65 and older, even if you're
healthy and active and take good care of yourself, you could be at increased risk for
pneumococcal pneumonia. Some risk factors, including smoking, and chronic conditions
may increase risks for pneumococcal pneumonia.
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Persons with pneumonia usually show respiratory and systemic symptoms, and
diagnosis is based on the clinical manifestation and radiological findings. The delayed
and insufficient antimicrobial therapy can lead to poor outcomes due to difficulty and
crucial pathogen identification. However there are new antibiotic and non-antibiotic
therapies, also fast and accurate diagnostic tests that can identify pathogens and
antibiotic resistance will improve the management of pneumonia. (Torres, A., Cilloniz,
C., Niederman, M.S. et al., 2021).
The patient has shown signs, symptoms, and factors that made her
diagnosed with bacterial pneumonia as evidenced by her answers on the patient
interview. Thus, further discussion of her situation is to be discussed in the next
chapters of this paper.
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PERSONAL DATA
A. Biographical Data
Name: Celia Asuncion
Age: 40 y/o
Birthday; February 20, 1981
Weight: 55 kg.
Height 150 cm.
Address: Toril Davao City
B. Medical Data
Chief Complaint: Five (5) days cough with fever, sharp pain in the chest while
coughing with shortness of breath.
PATIENT HISTORY
consultation. Chest pain is described as sharp when coughing. She had difficulty
breathing and fatigue.
The patient also stated that dyspnea occurs most especially after a busy
day at work. She declared that she took OTC drugs such as Paracetamol to
suppress the fever and Solmux for the cough.
C. Developmental Tasks
a. Erik Erikson’s Stages of Psychosocial development - The patient stated
that she is 40 years old thus according to this theory, she is not under the
seventh (7th) stage of development which specifies the conflict of
Generativity vs. Stagnation. The patient is said to be a wife and a mother
of 2 children and a teacher by profession. As the definition of this stage
goes, people tend to have the sense of world contribution by serving one’s
family and/or work (Myers, 2019). Thus, the patient has elicited
generativity in this stage of development.
b. Robert J. Havighurst Developmental task theory - Havighurst asserted that
throughout one’s entire lifespan, we develop through 6 individual stages
by means of resolving a problem or performance of developmental tasks.
This theory suggests that humans are always active learners interacting in
their social environments (Torg, 2019). Some examples of these tasks
include maintaining a standard of living, performing civic and social
responsibilities, and maintaining a relationship with a spouse. With these
given tasks, the patient will be said to have completed or is living with this
stage appropriate for her age.
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GENOGRAM
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GENOGRAM NARRATIVE
The patient’s grandfather on the maternal side died at the age of 71 with no
known disease while the grandmother died at the age 65 due to hypertension. On the
other hand, the patient’s grandfather on the paternal side died at the age of 74 and the
grandmother at the age of 72 with no known disease.
The mother of the patient is at the age of 70 and is currently diagnosed with
diabetes mellitus and hypertension. The patient’s father is 71 years old and has asthma.
The patient has 2 siblings, sibling #1 is currently 50 years old with no known disease
and the sibling #2 is 36 years old with no known disease. Patient CA is 40 years old and
currently has hypertension with an admitting diagnosis of pneumonia.
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ASSESSMENT
A. General Survey
The patient described that she is experiencing difficulty sleeping caused by a non
stop cough. She started feeling the loss in her appetite as her fever started. Her fever
has been associated with cold sweats. She has been experiencing fatigue due to work.
B. Vital signs
Temperature: 40°C
Blood Pressure: 130/60
C. Skin
Upon inspection, rashes, lumps, and sores are not visible.
Upon palpation, there are no changes in nails and hair noted. Cold skin was
noted.
D. Head
Upon Inspection, the head is normocephalic. The scalp was dry and hair was
evenly distributed. The facial movements are symmetrical.
Upon palpation, there were no lesions and deformities noted.
E. Eyes
Upon inspection, eyes are both symmetrical. The sclera is white and clear;
conjunctiva is transparent and appears pink. Pupils are equally round and
reactive to light accommodation. Both pupils have equal size of 3mm during light
accommodation.
Upon palpation, corneal reflex is present and the cornea is transparent. There
were no lumps and lesions noted.
F. Nose
Upon inspection, the nose is in the midline and no discharges. Both nares are
patent and nasal flaring was not noted.
Upon palpation, no bone and cartilage deviation were noted.
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G. Mouth
Upon inspection, lips were dry.
Upon palpation, no swelling and lesions were noted.
H. Neck
Upon inspection, trachea is located midline. No accessory muscle used during
respiration and work of breathing is decreased.
Upon palpation, there was no swelling and inflammation noted. Carotid pulse is
regular, Jugular vein is not distended.
J. Abdomen
Upon inspection, the abdomen was flat and brown in color.
Upon auscultation, no abnormal bowel movement sounds were noted.
Upon percussion, the abdomen is tympanic.
Upon palpation, it is soft, non-tender and no swelling was noted.
Introduction
Respiratory is a biological
system for all organisms
that involve gas exchange.
Body tissues receive
oxygen by the respiratory
system and the rate of
oxygen is increased during
exercise. Organs of the Respiratory System. The organs of the respiratory system can
be divided into two groups. The upper respiratory tract includes the nose, nasal cavity,
and pharynx and the lower respiratory tract includes the larynx, trachea, bronchial tree
and lungs.
The nose, pharynx, larynx, trachea and bronchi all work like a system of pipes through
which the air is funnelled down into our lungs. There, in very small air sacs called
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alveoli, oxygen is brought into the bloodstream and carbon dioxide is pushed from the
blood out into the air. When something goes wrong with part of the respiratory system,
such as an infection like pneumonia, it makes it harder for us to get the oxygen we need
and to get rid of the waste product carbon dioxide. Common respiratory symptoms
include breathlessness, cough, and chest pain.
When you breathe in, air enters your body through your nose or mouth. From there, it
travels down your throat through the larynx (or voicebox) and into the trachea (or
windpipe) before entering your lungs. All these structures act to funnel fresh air down
from the outside world into your body. The upper airway is important because it must
always stay open for you to be able to breathe. It also helps to moisten and warm the air
before it reaches your lungs.
The Lungs
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The lungs are paired, cone-shaped organs which take up most of the space in our
chests, along with the heart.
Their role is to take oxygen into
the body, which we need for our
cells to live and function
properly, and to help us get rid
of carbon dioxide, which is a
waste product. We each have
two lungs, a left lung and a right
lung. These are divided up into
‘lobes’, or big sections of tissue
separated by ‘fissures’ or
dividers. The right lung has
three lobes but the left lung has only two, because the heart takes up some of the space
in the left side of our chest. The lungs can also be divided up into even smaller portions,
called ‘bronchopulmonary segments’.
These are pyramidal-shaped areas which are also separated from each other by
membranes. There are about 10 of them in each lung. Each segment receives its own
blood supply and air supply.
Air enters your lungs through a system of pipes called the bronchi. These pipes start
from the bottom of the trachea as the left and right bronchi and branch many times
throughout the lungs, until they eventually form little thin-walled air sacs or bubbles,
known as the alveoli. The alveoli are where the important work of gas exchange takes
place between the air and your blood. Covering each alveolus is a whole network of
little blood vessels called capillaries, which are very small branches of the pulmonary
arteries. It is important that the air in the alveoli and the blood in the capillaries are very
close together, so that oxygen and carbon dioxide can move or diffuse between them.
So, when you breathe in, air comes down the trachea and through the bronchi into the
alveoli. This fresh air has lots of oxygen in it, and some of this oxygen will travel across
the walls of the alveoli into your bloodstream. Travelling in the opposite direction is
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carbon dioxide, which crosses from the blood in the capillaries into the air in the alveoli
and is then breathed out. In this way, you bring into your body the oxygen that you need
to live, and get rid of the waste product carbon dioxide.
Nervous Innervation
Dilation and constriction of the airway are achieved through nervous control by the
parasympathetic and sympathetic nervous systems. The parasympathetic system
causes bronchoconstriction, whereas the sympathetic nervous system stimulates
bronchodilation. Reflexes such as coughing, and the ability of the lungs to regulate
oxygen and carbon dioxide levels, also result from this autonomic nervous system
control. Sensory nerve fibers arise from the vagus nerve, and from the second to fifth
thoracic ganglia. The pulmonary plexus is a region on the lung root formed by the
entrance of the nerves at the hilum. The nerves then follow the bronchi in the lungs and
branch to innervate muscle fibers, glands, and blood vessels.
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Blood Supply
The major function of the lungs is to perform gas exchange, which requires blood from
the pulmonary circulation. This blood supply contains deoxygenated blood and travels
to the lungs where erythrocytes, also known as red blood cells, pick up oxygen to be
transported to tissues throughout the body. The pulmonary artery is an artery that arises
from the pulmonary trunk and carries deoxygenated, arterial blood to the alveoli. The
pulmonary artery branches multiple times as it follows the bronchi, and each branch
becomes progressively smaller in diameter. One arteriole and an accompanying venule
supply and drain one pulmonary lobule. As they near the alveoli, the pulmonary arteries
become the pulmonary capillary network. The pulmonary capillary network consists of
tiny vessels with very thin walls that lack smooth muscle fibers. The capillaries branch
and follow the bronchioles and structure of the alveoli. It is at this point that the capillary
wall meets the alveolar wall, creating the respiratory membrane. Once the blood is
oxygenated, it drains from the alveoli by way of multiple pulmonary veins, which exit the
lungs through the hilum
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PATHOPHYSIOLOGY
A. FACTORS
PREDISPOSING FACTORS
Pneumonia affects
children and families
Race -
everywhere, but is most
prevalent in South Asia
and sub-Saharan Africa.
(WHO, 2019)
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The incidence of
pneumonia is greater in
males than in females
but the total number of
deaths due to pneumonia
Gender -
has been higher among
females since the mid
1980s.
(Medscape, 2021)
(ERS, 2021)
PRECIPITATING FACTORS
B. DIAGRAM
Inflammation
Increased mucus
production
Vasolidation Cough
Airway
and increase &
obstruction
blood flow Sputum
producti
on
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Alveolar
capillary
leakage
Inflamed &
fluid-filled Hyperventilation
alveolar sac
Altered gas
exchange
Dyspnea
Ventilation perfusion
mismatch
MEDICATIONS
Clarithro
mycin
PO (Adults): Pharyngitis/tonsillitis 250 mg q
12hr for 10 days
PO (Children): Most infections 15 mg/kg/day Respiratory Failure
divided q 12hr for 7-14 days
Death
BAD PROGNOSIS
Levaquin
PO (Adults): Most infections 500-750mg q 12hr.
PO (Children 1-7 yr): Complicated urinary tract
infections 10-15 mg/kg q 12 hr (not to exceed 750
mg/dose) for 10-21 days.
IV (Adults): Most infections 400 mg q 12 hr.
Complicated urinary tract infections 400 mg q 12
hr for 7-14 days.
IV (Children 1-7 yr): Inhalation anthrax (post
exposure) 10 mg/kg q 12 hr (not to exceed 400
mg/dose) for 60 days
Penicillin G
Zithromax
MEDICAL MANAGEMENT
Complete blood count
Chest X Ray
Sputum Test
29
GOOD PROGNOSIS
LEGEND:
MEDICATIONS
30
MEDICAL MANAGEMENT
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C.NARRATIVE
Before a patient can develop pneumonia, it requires certain causes. The genetic
factor serves as the predisposing factor and the patient has experienced hypertension
and was exposed to second-hand smoke, and that contributes as the precipitating
factors. The microorganism gains access to the patient’s lungs through aspiration of
oropharyngeal contents, by inhalation of respiratory secretions, droplets, viruses or
bacteria. Once inhaled, the normal pulmonary defenses activate. The defense
mechanisms are associated with the cough reflex and use of mucociliary escalator,
secretory immunoglobulin A (IgA) antibodies and macrophages. These mechanisms
work to fight bacteria or viruses from entering the lungs and to prevent tissue damage.
Whether these defenses are effective or not, there are still bacteria that are hard and
dangerous that can still produce tissue damage and since the patient has an ineffective
immune response, it results in an overwhelming infection that leads to penetrate the
sterile lower respiratory tract. The organism multiplies and releases damaging toxins
and a bunch of different endotoxins can start producing tissue damage and can lead to
pneumonia. In response to tissue damage, there are chemicals that start releasing
inflammatory mediators of inflammation such as histamines, leucochenes,
prostaglandins and platelet activating factor. These mediators cause the vessels to
dilate, increasing the permeability so fluid starts leaking out and allowing more white
blood cells, proteins, inflammatory structures to come off to fight against the bacteria
and it can cause pyrexia or fever. The inflammation occurs and the patient has
experienced increased mucus production which resulted in airway constriction that
leads the patient to hyperventilate. On the other hand, vasodilation and increase of
blood flow also occurs that can result in alveolar capillary leakage and can produce
crackles. There is also an inflamed and fluid-filled alveolar sac and altered gas
exchange and the patient may experience hypoxemia. These factors decreased the
patient’s lung compliance and dyspnea or shortness of breath happened. If treated with
proper management, therapy and medications, the patient will have a good prognosis.
But if not treated it will lead to more complications like Pleural effusion, Empyema,
Pleurisy, Bacteremia, Septic shock and even death.
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MEDICAL MANAGEMENT
Neutrophils 90 % 45-75%
Lymphocytes 70 % 20-45%
Eosinophils 4 % 02-06%
Monocytes 4 % 02-10%
Interpretation/narrative:
CBC showed that her TLC (Total Leukocytes count) increased 20000 mm3 with a
normal value of 5500-18000/cm and lymphocytes concentration was 70% which
exceeded the normal range of leukocytes from 20-45%. Whereas neutrophils showed a
result of 90% which exceeded the normal values of 45-75%. These results suggest that
the patient’s immune system responds to the invasive microorganism that enters in her
body as well as the infection.
4. After the procedure, let the patient wait or comes back a day after the test.
2. Make sure to educate patients to take samples before eating in order to prevent
aspiration as well as making sure that the patient’s bolus does not mix with their
sputum.
3. Instruct the patient to just wait for the result after 2-3 days.
Results of sputum test: Sputum culture is positive of Streptococcus pneumoniae; the
causative agent of bacterial pneumonia. A positive result to Gram staining suggests that
bacteria is the cause of the pneumonia and not virus.
POSSIBLE TESTS:
a. Arterial Blood gases - This test uses extracted blood from an artery that
measures different parameters such as the pH, oxygen, bicarbonate, and carbon
dioxide in the blood. This test would see how the lungs function. In connection to
pneumonia, in cases where it worses, ABG could help monitor the patient
especially when in dyspneic stages to properly administer care needed.
b. CT (computed tomography) scan- This test helps evaluate the severity of lung
infection and also to look for other non-infectious causes of the disease. For
pneumonia patients, since the lungs are under infection, this test will be an
additional diagnostic test for further assessing the need for additional
interventions.
c. Bronchoscopy— This procedure includes seeing inside the lungs using a flexible
instrument with a camera on its end. For our patient’s case, this may be used
when she does not respond well to medications and treatments to see if there
are any underlying causes of the decline.
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DRUG STUDY 1
Brand Name:
Biaxin, Biaxin XL
Generic Name:
Clarithromycin
Classification:
Pharmacology: macrolides
Pregnancy Category C
Mode of Action:
Dosage:
days or 1000mg once daily for 7 days as XL tablets; skin/skin structure infections 250
mg q 12hr for 7-14 days; H. Pylori 500mg 2-3 times daily with a proton pump inhibitor
(lansoprazole or omeprazole) or ranitidine with or without amoxicillin for 10-14 days;
Endocarditis prophylaxis 500 mg 1hr before procedure; MAC prophylaxis/treatment 500
mg twice daily, for active infection another antimycobacterial is required.
PO (Children): Most infections 15 mg/kg/day divided q 12hr for 7-14 days (up to 500
mg/dose for MAC). Endocarditis prophylaxis 15 mg/kg 1 hr before procedure.
Renal Impairment::
PO (Adults): Ccr <30ml/min, 250 mg 1-2 times daily, a 500 mg initial dose may be used.
PO (Children): Ccr <30 ml/min, decrease dose by 50% or double dosing interval.
Indications:
Contraindications:
Use cautiously in: Severe liver or renal impairment (dose adjustment required if Ccr
<30ml/min).
CNS: headache
Drug Interaction:
RT Management:
● Administer around the clock, without regard to meals.
Rationale: Because food shows but does not decrease the extent of absorption.
● Always check for his/her vital signs.
Rationale: In order to have the baseline data and to know if you can administer
the drug.
● RT should provide patient teaching.
39
Rationale: Giving the patient important information about their prescription could
include things like precautions, directions, and guidelines for using it.
● Also keep an eye on the patient's gastrointestinal condition.
Rationale: Clarithromycin has adverse side effects that can affect the GI and
could manifest such as pseudomembranous colitis, abdominal pain/discomfort,
abnormal taste, diarrhea, dyspepsia, nausea.
● Instruct the patient to notify the health care professional if symptoms do not
improve within a few days.
Rationale: In order to monitor his/her mental and physical state.
● Caution patients taking zidovudine that clarithromycin and zidovudine must be
taken at least 4 hr apart.
Rationale: To help keep drug interactions and unwanted effects to a minimum.
● Assess the patient for infection at the beginning of and during therapy
Rationale: In order to determine if the patient is healthy enough to undergo
surgery and if he or she is stable.
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DRUG STUDY 2
Pharmacologic: fluoroquinolones
Pregnancy Category C
Dosage:
Renal Impairment
Gemifloxacin
PO (Adults): Acute bacterial exacerbation of chronic bronchitis 320 mg once daily for 5
days; Community-acquired pneumonia (CAP) caused by Klebsiella pneumoniae,
Moraxella catarrhalis, and multidrug resistant strains of S. pneumonia 320 mg once
daily for 7 days. Community-acquired pneumonia (CAP) caused S. pneumonia,
Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydia pneumonia, and
multidrug resistant strains of S. pneumonia 320 mg once daily for 5 days.
Renal Impairment
Levofloxacin
42
PO, IV (Adults): Most infections 250-750 mg q 24 hr; inhalation anthrax (post exposure)
500 mg once daily for 60 days.
Renal Impairment
PO, IV (Adults): Normal renal function dosing of 750 mg/day: CCr 20-49 ml/min 750 mg
q 48 hr; CCr 10-19 ml/min 750 mg initially, then 500 mg initially then 250 mg q 24 hr;
CCr 10-19 ml/min 500 mg initially then 250 mg q 48 hr. Normal renal function dosing of
250 mg/day: CCr 10-19 ml/min 250 mg q 48 hr.
Moxifloxacin
PO, IV (Adults): Bacterial sinusitis 400 mg once daily for 10 days. Community-acquired
pneumonia 400 mg once daily for 7-14 days. Acute bacterial exacerbation of chronic
bronchitis 400 mg once daily for 5 days. Complicated intra abdominal infection 400 mg
once daily for 5-14 days. Urethritis/cervicitis 300 mg q 12 hr for 7 days. Skin/skin
structure infections 400 mg/day for 7-21 days.
Norfloxacin
PO, IV (Adults): Uncomplicated urinary tract infections 400 mg q 12 hr for 3-14 days.
Complicated urinary tract infections 400 mg q 12 hr for 10-21 days. Gonorrhea 800 mg
single dose. Prostatitis 400 mg q 12 hr for 4-6 wk.
Renal Impairment
Ofloxacin
Otic (Adults and Children ≥6 mo): Otitis externa 6 months to 13 yr 5 drops instilled into
affected ear once daily for 7 days; Otitis externa ≥13 yr 10 drops instilled into affected ear
43
once daily for 7 days. Acute otitis media in pediatric patients 1-12 yr old with
tympanostomy tubes 5 drops instilled into affected ear twice daily for 10 days.
Chronic suppurative otitis media with perforated tympanic membranes in patients ≥12 yr
q0 drops instilled into the affected ear twice daily for 14 days.
Renal Impairment
PO, IV (Adults): CCr 20-50 ml/min 100% of the usual dose q 24 hr; CCr <20ml/min
50% of the usual dose q 24 hr.
Indications:
PO, IV: Treatment of the following bacterial infections: Urinary tract infections including
cystitis and prostatitis (ciprofloxacin, levofloxacin, norfloxacin, ofloxacin), Gonorrhea
(may not be considered first-line agents due to increasing resistance), Gynecologic
infections (ciprofloxacin, norfloxacin, ofloxacin), Respiratory tract infections including
acute sinusitis, acute exacerbations of chronic bronchitis, and pneumonia (not
norfloxacin), Skin and skin structure infections (levofloxacin, moxifloxacin, ciprofloxacin,
ofloxacin), Bone and joint infections (ciprofloxacin), Infectious diarrhea (ciprofloxacin,
moxifloxacin). Febrile neutropenia (ciprofloxacin). Post-exposure treatment of inhalation
anthrax (ciprofloxacin, levofloxacin).
Contraindications:
Use cautiously: Mixed CNS depressant overdose (effects of other agents may emerge
when benzodiazepine effect is removed); History of seizures (seizures are more likely to
occur in patients who are experiencing sedative/hypnotic withdrawal, who have recently
received repeated doses of benzodiazepines, or who have a previous history of seizure
44
activity); Head injury (may increase intracranial pressure and risk of seizures); Severe
hepatic impairment; Pregnancy, lactation (safety not established); Pedia: children <2 yr
(safety not established).
Neuro: paresthesia,
Drug Interactions:
RT Management:
Rationale: Due to the drug interactions and may enhance the anticoagulant
effects of warfarin.
Rationale: Because food can interfere with absorption, this will ensure that the
tablets have a greater chance of combating the infection.
Rationale: In order to avoid any complications that can cause death. Always have
an epinephrine on your side.
● Advise patients to notify health care professionals immediately if they are taking
theophylline.
● Instruct patients being treated for gonorrhea that partners also must be treated.
Rationale: To prevent phototoxicity reactions during and for 5 days after therapy.
DRUG STUDY 3
Pharmacologic: penicillins
Pregnancy Category B
Dosage:
Penicillin G (Aqueous)
Infants >7 days): 25,000 units/kg q 8 hr; meningitis 50,000-75,000 units/kg q 6 hr.
Penicillin V
PO (Adults and Children ≥ 12 yr): Most infections 125-500 mg q 6-8 hr. Rheumatic
fever prevention 125-250 mg q 12 hr.
Benzathine Penicillin G
Procaine Penicillin G
Contraindication:
Use cautiously in: Geri: Geriatric patients (consider decreased body mass, age-related
decrease in renal/hepatic/cardiac function, intercurrent disease and drug therapy);
Severe renal insufficiency (dose reduction recommended)
CNS: seizures
49
Drug Interactions:
RT Management:
Rationale: Persons with a negative history of penicillin sensitivity may still have
an allergic response.
Rationale: Due to accident injury near or into a nerve can result in severe pain
and dysfunction.
DRUG STUDY 4
Classification: Macrolides
Mode of Action:
Azithromycin binds to the 23S rRNA of the bacterial 50S ribosomal subunit. It stops
bacterial protein synthesis by inhibiting the transpeptidation/translocation step of protein
synthesis and by inhibiting the assembly of the 50S ribosomal subunit.
Dosage:
Community-acquired pneumonia:
Oral: ADULT
Parenteral: 500 mg IV once a day as a single dose for at least 2 days, followed by 500
mg (immediate-release formulation) orally to complete a 7- to 10-day course of therapy.
PEDIATRIC
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Extended-release:
-Patients less than 34 kg: 60 mg/kg (maximum dose: 2 g/dose) orally as a single dose
Parenteral: 500 mg IV once a day as a single dose for at least 2 days, followed by 500
mg (immediate-release formulation) orally to complete a 7- to 10-day course of therapy
Indications:
Azithromycin should be used only to treat or prevent infections that are proven or
strongly suspected to be caused by susceptible bacteria in order to prevent the
development of antimicrobial resistance and maintain the efficacy of azithromycin.
Azithromycin is indicated for the treatment of patients with mild to moderate infections
caused by susceptible strains of the microorganisms listed in the specific conditions
below. Recommended dosages, duration of therapy and considerations for various
patient populations may vary among these infections. Refer to the FDA label and
"Indications" section of this drug entry for detailed information.
Adults:
Genital ulcer disease in men due to Haemophilus ducreyi (chancroid). Due to the small
number of women included in clinical trials, the efficacy of azithromycin in the treatment
of chancroid in women has not been established.
Pediatric Patients
Contraindications:
● nausea,
● abdominal pain,
● stomach upset,
● vomiting,
● constipation,
● dizziness,
● tiredness,
● headache,
● vaginal itching or discharge,
● nervousness,
● sleep problems (insomnia),
● skin rash or itching,
● ringing in the ears,
● hearing problems,
● or decreased sense of taste or smell.
Drug Interaction:
Azithromycin may interact with other medications a person is taking. For example, using
azithromycin while taking nelfinavir, which is a drug that helps treat HIV, can increase
the risk of liver abnormalities and hearing problems. Azithromycin can also increase the
effects of blood thinners such as warfarin. Other drugs that may interact with
azithromycin include:
RT Management:
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5.) Tell your patient that they may experience these side effects: Stomach cramping,
discomfort, diarrhea; fatigue, headache.
6.) Report severe or watery diarrhea, severe nausea or vomiting, rash or itching, mouth
sores, vaginal sores.
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DRUG STUDY 5
Classification: Macrolide
Mode of Action:
Dosage:
Oral
Indications:
Contraindications:
Hypersensitivity.
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RT Management:
1.) Instruct the patient to take fidaxomicin twice daily, 12 hrs. apart, as directed for the
full course of therapy, even if feeling better.
Rationale: Skipping doses or not completing a full course of therapy may decrease
effectiveness of therapy and increase risk that bacteria will develop resistance and not
be treatable in the future.
2.) Advise the patient to notify the health care professional of all Rx or OTC
medications, vitamins, or herbal products being taken and to consult with health care
professionals before taking other medications.
Rationale: Because some medicines may interfere and can cause unpleasant to the
patient and have dangerous side effects.
Rationale: Because there are some cases that dificid can harm your baby while you are
pregnant. If you are pregnant, you and your doctor should decide together if you will
take dificid.
4.) Monitor bowel function for diarrhea, abdominal cramping, fever, and bloody stools.
May begin up to several weeks following cessation of antibiotic therapy.
Rationale: Check with your doctor immediately if the symptoms don't stop.
5.) Monitor for signs and symptoms of hypersensitivity reactions (dyspnea, pruritus,
rash, angioedema of mouth, throat, and face) periodically during therapy. Risk
increases with a macrolide allergy.
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DRUG STUDY 6
Clinical: Antihypertensive
Indication/Dosage: Hypertension:
PO: Adults & Elderly: 50mg/day initially. May be given once or twice
daily, total dose in a day ranging from 25-100mg. Children 6-16yrs:
0.7 mg/kg once daily. Adjust dose based on BP.
Diabetic Nephropathy:
9. Assess patient for any possible side effects or adverse effects for
documentation, report to attending physician if effects are present
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DRUG STUDY 7
Indication/Dosage:
RT Management:
● Consult a physician for use in children younger than 2 yrs, oral use
longer than 5 days (children) or longer than 10 days (adults), or
fever lasting longer than 3 days to prevent complications.
DRUG STUDY 8
Side Effects: Common Side effects: diarrhea and feeling or being sick.
Serious side effects: in rare cases, anaphylaxis.
Adverse Effects: Nausea, stomach discomfort, diarrhea, and skin rashes are the
most common undesirable effects.Carbocisteine rarely
causes dizziness, insomnia, headache, palpitations, mild
lowering of blood glucose, dryness of mouth, abnormal heart
rhythm (atrial fibrillation), and "gassiness".
Drug Interaction: Patients should always tell their doctor if they are taking other
medicines, including herbal medicines and food
supplements.
RT Management:
DRUG STUDY 9
Mode of Action: Biotin catalyzes the action of the B and C vitamins for faster results.
Calcium is significant in the excitation mechanisms of the
nerve and muscle cells important for muscle contraction. The
effervescent form of Berocca allows the body to
quickly and completely absorb the essential vitamins and
minerals.
Adverse Effects: Constipation, diarrhea, or upset stomach may occur. These effects
are usually temporary and may disappear as your body
adjusts to this medication. If any of these effects persist or
worsen, contact your doctor or pharmacist promptly.
Drug Interaction: If your physician has directed you to use this medication, your
doctor may already be aware of any possible drug
interactions and may be monitoring you for them. Do not start,
stop, or change the dosage of any medicine before checking with
your doctor, health care provider or pharmacist first.
RT Management:
RT interventions:
RT interventions:
a. Assess the characteristic of the pain - the type of pain may vary from sharp,
constant, or stabbing. It may also be assessed by the location and intensity. This
assessment will suggest the onset of the complications.
b. Monitor vital signs - changes in this especially in the HR and BP is an indication
that the patient is experiencing pain.
c. Provide procedures that will promote comfort - aside from administering pain
relievers, back rubs, position changes, and breathing exercises will control the
pain.
d. Encourage oral hygiene - mouth breathing is one of the suggested breathing
exercises and this may dry out mucous membranes that will lead to more
discomfort.
e. Administer analgesics and/or antitussives - these medications may suppress
cough and thus will minimize its persistence that causes pain. Therefore, it will
improve comfort.
f. Instruct patient to support chest when coughing (chest splinting) - this will aid
support and control chest discomfort during cough.
g. Position the patient in a comfortable position - this may lessen the discomfort
brought by pain.
72
RT Care Plan 3
RT Interventions:
a. Assess the patient’s typical level of exercise and physical movement. - Increased
physical exertion and inadequate levels of exercise can add to fatigue.
Encourage the patient to avoid overexertion and possible exacerbation of
symptoms.
b. Position the patient on semi fowlers - The patient should assume a comfortable
position to promote rest and breathing and should change positions frequently to
enhance secretion clearance and pulmonary ventilation and perfusion.
c. Adequate hydration of 2 to 3 liters of water per day - thins and loosens
pulmonary secretions, also to avoid dehydration and help the patient to recover
more quickly
d. Promote sufficient nutritional intake. - The patient will need properly balanced
intake of fats, carbohydrates, proteins, vitamins, and minerals to provide energy
resources.
e. Evaluate the patient’s outlook for fatigue relief, eagerness to participate in
strategies to reduce fatigue, and level of family and social support. - These will
promote active participation in planning, implementing, and evaluating
therapeutic management to alleviate fatigue.
f. Instruct patient and family about the cause of pneumonia, management of
symptoms, signs, and symptoms, and the need for follow-up.
g. Instruct the patient about the factors that may have contributed to the
development of the disease.
73
74
- Hydration therapy. Fluids hydrate the body, loosen mucus in the lungs, and help
bring up phlegm. Take in lots of water.
- Oxygen therapy. Patients who are unable to breathe sufficiently on their own
might benefit from oxygen supplementation.
Hygiene
Hygiene and maintaining healthy personal habits can help you stay healthy and feel
good about yourself. Learn the personal hygiene routines you should incorporate into
your daily routine. You can also help prevent pneumonia and other respiratory infections
by following good hygiene practices.
- Wash your hands. Washing your hands before preparing or eating food, after
going to the bathroom, after coughing or sneezing, and after handling garbage, goes a
long way toward preventing the spread of bacteria and viruses.
- Make sure to clean your environment
Out Patient
- Patients must be informed about any potential warning signs or symptoms that
may occur.
- Encourage the patient or the significant other to see doctor if there is a problem
regarding with the patient’s health
- Remind the patient and the significant other to do follow up check-up and for
them to know the progress
- Do not smoke. Allowing others to smoke around you is not a good idea. Your
cough will persist longer if you smoke
Diet
- Starches and saccharine-containing foods should be avoided. The loss of fluid
induced by diarrhoea and/or perspiration is linked to an increased demand for
fluid in pneumonia.
- The carbohydrate content of whole grains such as quinoa, brown rice, oats, and
barley gives energy to the body. They include B-vitamins, which aid in the
generation of energy and the regulation of body temperature. The mineral
selenium included in these grains helps to improve the immune system.
76
PROGNOSIS
The patient is 40 years old and sought medical attention at the Pulmonary
Department consultation room of San Pedro Hospital on July 14, 2021, 15:00. To further
assess the patient, tests were performed namely, complete blood count, chest x ray,
and sputum test.
The main goal of the respiratory therapists is to give care to the patient to
improve the cardiorespiratory state of the patient. We are tasked to help other members
of the healthcare team to give holistic attention to the patient. Continuous medication
and care is a must to improve the patient’s condition and avoid further complications.
After all the treatments aided to the patient, it is believed that she had a good
prognosis given that she is not hospitalized and is only prescribed home remedies.
78
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