DRUG ORDER MECHANISM INDICATIONS CONTRAINDICATIONS ADVERSE NURSING

(Generic Name, OF ACTION EFFECTS OF RESPONSIBILITIE

Brand Name, THE DRUGS S/ PRECAUTIONS
Classification,
Dosage, Route,
Frequency)

Generic Name: The short term Prednisolone is The most Nursing

Prednisolone effects of indicated to treat common side responsibility:
corticosteroids are endocrine, effects of Monitor and report
Brand Name: decreased rheumatic, and prednisolone are signs of peptic
Pediapred, vasodilation and hematologic insomnia, weight ulcer, including
FloPred, Orapred, permeability of disorders; gain, indigestion heartburn, nausea,
Orapred ODT, capillaries, as well collagen, and sweating a vomiting blood,
Millipred, Millipred as decreased dermatologic, lot. Taking tarry stools, and
DP, Prelone Syrup, leukocyte migration ophthalmic, prednisolone can loss of appetite.
Veripred 20 to sites of respiratory, and make you more Assess signs of
inflammation. gastrointestinal likely to get increased
Classification: Corticosteroids diseases; allergic infections. Tell intracranial
Corticosteroids binding to the and edematous your doctor if pressure in
glucocorticoid states; and other you're exposed children, including
Route: Oral receptor mediates conditions like to infectious changes in mood
changes in gene tuberculous illnesses like and behavior,
Frequency: 10mg expression that meningitis. chickenpox or decreased
1 tablet p.o. PC lead to multiple shingles. consciousness,
lunch downstream effects headache, lethargy,
over hours to days. seizures, and
vomiting.
Glucocorticoids
inhibit neutrophil
apoptosis and
demargination; they
inhibit
phospholipase A2,
which decreases
the formation of
arachidonic acid
derivatives; they
inhibit NF-Kappa B
and other
inflammatory
transcription
factors; they
promote
anti-inflammatory
genes like
interleukin-10.

Lower doses of
corticosteroids
provide an
anti-inflammatory
effect, while higher
doses are
immunosuppressiv
e. High doses of
glucocorticoids for
an extended period
bind to the
mineralocorticoid
receptor, raising
sodium levels and
decreasing
potassium levels.