Patient’s Name:___________________ Age:_________________ Sex: ________

Address: ______________________________________________
Admitting Diagnosis: ____________________________________

DRUG STUDY
GENERIC NAME BRAND INDICATIONS AND NURSING
ACTION CONTRAINDICATION ADVERSE EFFECT
NAME DOSAGES RESPONSIBILITIES
Destroys  Respiratory tract, skin, and ● Hypersensitivity to CNS: lethargy,  Tell patient that
AMPICILLIN OMNIPEN bacteria by soft- tissue infections caused penicillins, hallucinations, anxiety, medication may
inhibiting by Haemoph- ilus influenzae, cephalosporins, confusion, agitation, cause nausea or
bacter- ial staphylococci, and streptococci imipenem, or other beta- depression, fatigue, vomiting (small,
Adults and children weighing dizziness,seizures CV: frequent meals,
cell-wall lactamase inhibitors
40 kg (88 lb) or more: 250 to vein irritation, frequent mouth care,
synthesis 500 mg I.V. or I.M. q 6 hours sucking lozenges, or
during thrombophlebitis, heart
Adults and children weighing failure chewing gum may
microbial less than 40 kg (88 lb): 25 to help); or diarrhea
multiplicati EENT: blurred vision,
50 mg/kg/day I.M. or I.V. in (buttermilk, boiled
on itchy eyes
divided doses q 6 to 8 hours milk, or yogurt may
GI: nausea, vomiting,
Adults and children weighing help).
more than 20 kg (44 lb): 250 diarrhea, abdominal
mg P.O. q 6 hours pain, enterocolitis,  Instruct client to
Children weighing 20 kg (44 gastritis, stomatitis, maintain adequate
lb) or less: 50 mg/kg/day P.O. glossitis, black “hairy” hydration (2-3 L/day
in divided doses q 6 to 8 hours tongue, furry tongue, of fluids) unless
 Prophylaxis for neonatal group oral or rectal instructed to restrict
B streptococcal disease candidiasis, fluid intake.
Adult women: During labor, pseudomembranous
loading dose of 2 g I.V.; then 1 colitis
g I.V. q 4 hours until delivery GU: vaginitis,
 N. gonorrhoeae infections nephropathy,
Adults: Single dose of 3.5 g interstitial nephritis
P.O. given with l g probenecid Hematologic: anemia,
Children weighing 40 kg (88 eosinophilia,
lb) or more: 500 mg I.M. or agranulocytosis,
I.V. q 6 hours Children hemolytic anemia,
weighing less than 40 kg (88 leukopenia,
lb): 50 mg/kg/day in divided thrombocytopenic
doses q 6 to 8 hours purpura,
  Urethritis caused by N.
gonorrhoeae (in males)
Adults and children weighing
40 kg (88 lb) or more: 500 mg
I.V. or I.M., repeated 8 to 12
hours later ➣ Prophylaxis
against sexually trans- mitted
diseases in adult rape victims
Adults: 3.5 g P.O. with l g
probenecid as a single dose
METOCLOPRAMIDE REGLAN Blocks ➣ To prevent chemotherapy-
dopamine induced vomiting
receptors by Adults: 1 to 2 mg/kg I.V. 30
disrupt- ing minutes before chemotherapy,
CNS then q 2 hours for two doses,
chemorecept then q 3 hours for three
or trigger additional doses
zone,
➣ To facilitate small-bowel
increasing intubation; radiologic
peristalsis
examination when delayed
and gastric emptying interferes
promoting Adults and children older
gastric than age 14: 10 mg I.V. as a
emptying single dose
Children ages 6 to 14: 2.5 to 5
● Hypersensitivity to
drug
● Pheochromocytoma
● Parkinson’s disease
● Suspected GI
obstruction, perfora- tion,
or hemorrhage
● History of seizure
disorders
thrombocytopenia,
neutropenia
Hepatic: nonspecific
hepatitis
Musculoskeletal:
arthritis exacerbation
Respiratory: wheezing,
dyspnea, hypoxia,
apnea Skin: rash,
urticaria, fever,
diaphoresis Other: pain
at injection site,
superin- fections,
hyperthermia,
hypersensitiv- ity
reaction, anaphylaxis,
serum sickness
CNS: drowsiness,
restlessness, anxiety,
depression, irritability,
fatigue, lassi- tude,
insomnia, tardive
dyskinesia,
parkinsonian-like
reactions, extrapyra-
midal reactions,
akathisia, dystonia
hypertension,
hypotension,
arrhythmias,
neuroleptic malignant
 mg I.V. as a single dose syndrome
Adults: 10 mg P.O. 30 minutes GI: nausea,
before meals and at bedtime for constipation, diarrhea,
2 to 8 weeks. If patient can’t dry mouth
tolerate P.O. doses, give same
GU: gynecomastia
dosage I.V. or I.M.
➣ Gastroesophageal reflux
Adults: 10 to 15 mg P.O. 30
minutes before meals and at
bedtime for up to 12 weeks. For
prevention, single dose of 20
mg (some patients may respond
to doses as small as 5 mg).
PARACETAMOL TEMPRA Reduces  Used for the relief of the  Contraindicated with  Chest pain C - Analgesic and
fever by fever, headaches, and other allergy to  Dyspnea Antipyretic
acting on the pain regarding surgeries acetaminophen or any H - Relief of fever,
 Rash
hypothalamu wound. component. headaches, and other
s to cause  Fever minor aches and pains.
 Dosages: 500 mg  Use cautiously with  Acute kidney
vasodilatatio E - as necessary or when
n& impaired hepatic failure temperature is more than
sweating. function, chronis  Jaundice 37.80C
Used for the alcoholism, and  Acute kidney C - Instruct client to
relief of pregnancy lactation. failure report any adverse
fever, reaction like allergies to
 Hepatic toxicity
headaches, the physician or nurse.
and other
and failure Warn patient that high
and pains doses or unsupervised
regarding long –term use can cause
surgical liver damage.
wound. K - Do not exceed the
recommended dosage.
Not to use for marked
fever (temperature higher
 than 39.50C). Fever
persisting longer than 3
days.
RANITIDINE ZANTAC Competitive  Used to prevent ulcer while  Hypersensitivity to  Constipation C - Gastointestinal agent;
inhibition of patient is on pNPO. ranitidine or any  Diarrhea Antisecretory (H2-
histamine at component of the receptor antagonist)
 Fatigue
H2 formulation. H - Reduced amount of
 Headache acid in the stomach that
receptors of
 Insomnia may result to prevented
the gastric
parietal
 Muscle pain ulcer incidence.
cells, which  Nausea E - Every 8 hours while
 Vomiting patient is on NPO.
inhibits
C - Instruct client to
gastric acid  Agitation
report any adverse
secretion,  Anemia reaction to the physician
gastric  Confusion or nurse. Tell patient that
volume, and  Depression antacids may decrease
hydrogen  Easy bruising or the absorption of
ion bleeding ranitidine.
concentratio K - Ranitidine can
n are interfere with the
reduced. metabolism of alcohol.
Does not Patients taking ranitidine
affect pepsin who drink alcohol may
secretion, have elevated blood
pentagastrin alcohol level
stimulated
intrinsic
factor
secretion, or
serum
gastrin.
Patient’s Name:___________________ Age:_________________ Sex: ________
Address: ______________________________________________
Admitting Diagnosis: ____________________________________

DRUG STUDY
GENERIC NAME BRAND ACTION INDICATIONS AND ADVERSE NURSING
CONTRAINDICATION
NAME DOSAGES EFFECT RESPONSIBL
BETAHISTANIN SERC Exerts a relaxant action on  Hypersensitivity to  Previous  Mild gastric  Instruct patient
E the precapillary betahistine or hypersensitive reaction complaints should be taken
sphincters of the to any of the to the drug  skin rashes food.
microcirculation of the excipients of  Serc
inner ear, and thereby
 Patients with
increases the blood supply
to the striavascularis of the
phaeochromocy
labyrinth. or bronchial as
Investigations into the should be treate
acute, subacute and extra care
chronic effects of 
betahistine in animals
have demonstrated the low
toxicity and safety of the
drug.
CAPTOPRIL CAPOTEN Prevents conversion of ➣ Hypertension ● Hypersensitivity to drug or CNS: headache,  Monitor b
angiotensin I to Adults: 12.5 to 25 mg other ACE inhibitors dizziness, pressure a
angiotensin II, which P.O. two to ● Angioedema (hereditary or drowsiness, fatigue, pulse freq
leads to decreased three times daily; may be idiopathic) weakness, insomnia
vasoconstriction and, increased ● Pregnancy CV: angina pectoris,  Monitor w
ulti- mately, to lower up to 150/mg/day at 1- to tachycardia, and assess
blood pressure. Also 2-week hypotension patient fre
decreases blood intervals. Usual dosage is EENT: sinusitis
for signs o
pressure by increasing 50 mg GI: nausea, diarrhea,
overload i
plasma renin secretion t.i.d. If patient is anorexia concurren
from kidney and receiving GU: proteinuria, diuretic th
reducing aldosterone diuretics, start with 6.25 erectile dysfunction,
secretion from adrenal to 12.5 decreased libido,  Assessmen
cortex. mg P.O. two to three gynecomastia, renal urine prot
Decreased aldos- terone times daily. If failure be ordere
secretion prevents blood pressure isn’t Hematologic:
sodium and water adequately anemia,
 Proteinuri
retention. con- trolled after 1 to 2 agranulocyto- sis,
nephrotic
weeks, add leukopenia,
diuretic, as prescribed. If pancytopenia, syndrome
further throm- bocytopenia occur with
blood pressure decrease Metabolic: therapy.
is needed, hyperkalemia
dosage may be raised to Respiratory: cough,  Monitor B
150 mg asthma, bronchi- tis, Crea and
P.O. t.i.d. while patient dyspnea, electrolyte
continues eosinophilic periodical
on diuretic. Maxi- mum pneumonitis
dosage is Skin: rash,  WBC shou
450 mg/day. angioedema monitored
➣ Heart failure to therapy
Adults: Usual initial periodical
dosage is 25 thereafter
mg P.O. t.i.d. After cause false
increasing to positive re
50 mg P.O. t.i.d. (if
urine acet
indicated), do
not increase dosage
further for 2
weeks, to deter- mine
satisfactory
response. Don’t exceed
 450
mg/day.
➣ Left ventricular
dysfunction after
myocardial infarction
Adults: 6.25 mg P.O. as
a test
dose, fol- lowed by 12.5
mg t.i.d.
May increase up to 50 mg
t.i.d.
➣ Diabetic nephropathy
Adults: 25
mg P.O. t.i.d
CEFUROXIME CEFATIN Interferes with ➣ Moderate to severe ● Hypersensitivity to CNS: headache, Before
bacterial cell-wall infections, including those of cephalosporins or penicillins hyperactivity,
synthesis and division skin, bone, joints, urinary or hyperto- > Tell pt to report
by binding to cell wall, respiratory tract, ● Carnitine deficiency nia, seizures of allergic reaction
causing cell to die. gynecologic infections GI: nausea, penicillins and
Active against gram- Adults and children ages 12 vomiting, diarrhea, cephalosporins
negative and gram- and older: 750 mg to 1.5 g abdominal pain, > Note reasons for
positive bacteria, with I.M. or I.V. q 8 hours for 5 to dyspepsia, therapy, baseline
expanded activity 10 days or 250 to 500 mg pseudomembranou assessments
against gram-negative P.O. q 12 hours s colitis > Assess for anem
bacteria. Exhibits Children ages 3 months to GU: hematuria, dysfunction. Redu
minimal 12 years: 50 to 100 vaginal candidiasis, with impaired ren
immunosuppressant mg/kg/day I.V. or I.M. in renal dysfunction, function
activity. divided doses q 6 to 8 hours acute renal failure > Assess if the pt h
➣ Gonorrhea Hematologic: taken drug that m
Adults: 750 mg to 1.5 g I.M. hemolytic anemia, decrease the med
or I.V. as a single dose, or aplastic anemia, effectiveness
1.5 g I.M. (750 mg in two hemorrhage > Inform patient n
 separate sites), given with 1 Hepatic: hepatic importance of the
g probenecid P.O. dysfunction him/her
➣ Bacterial meningitis Metabolic:
Adults and children ages 12 hyperglycemia During
and older: Up to 3 g I.V. or Skin: toxic
I.M. q 8 hours epidermal > Administer med
Children ages 3 months to necrolysis, ery- with food to haste
12 years: 200 to 240 mg/kg thema multiforme, absorption
I.V. daily in divided Stevens-Johnson >If pt has difficulty
doses q 6 to 8 hours syndrome swallowing, tell hi
➣ Otitis media Other: allergic it may be crushed
Children ages 3 months to reaction, drug fever, dissolved but warn
12 years: 15 mg/kg P.O. q 12 superinfection, about its bitter tas
hours (oral suspension) for anaphylaxis is hard to mask, ev
10 days, or 250 mg (tablets) Interactions food
P.O. q 12 hours for 10 days Drug-drug. Antacids > Inspect IM and I
➣ Pharyngitis; tonsillitis containing injection sites freq
Adults and children ages 13 -cess, for signs of p
and older: 250 mg P.O. b.i.d. > Monitor I&O rat
for 10 days pattern: Especially
Children ages 3 months to important in sever
12 years: 125 mg P.O. q 12 patients receiving
hours for 10 days, or doses. Report any
20 mg/kg/day P.O. in two significant change
divided doses for 10 days as > Observe 15 R's o
oral suspension (maximum administration
500 mg/day)
KETOROLAC TORADOL Interferes with ➣ Moderately severe acute ● Hypersensitivity to drug, its CNS: drowsiness,  Be aware
prostaglandin pain components, aspirin, or other headache, dizziness patient ma
biosynthesis by Adults younger than age 65: NSAIDs CV: hypertension increased
inhibiting Initially, 30 mg I.V. or 60 mg ● Concurrent use of aspirin, EENT: tinnitus CV events
cyclooxygenase I.M. as a single dose, or 30 other NSAIDs, or probenecid GI: nausea, bleeding,
pathway of arachidonic mg I.M. or I.V. q 6 hours, ● Peptic ulcer disease vomiting, diarrhea, toxicity m
acid metabolism; also not to exceed 120 mg/day. ● GI bleeding or perforation constipation, according
acts as potent inhibitor To switch to P.O. therapy, ● Advanced renal flatulence,
of platelet aggregation. give 20 mg P.O. initially for impairment, risk of renal dyspepsia,  May incre
patients who received single failure epigastric of bleedin
30-mg I.V. or 60-mg I.M. ● Increased risk of bleeding, pain, stomatitis not use w
dose, followed by 10mg P.O. suspected or confirmed Hematologic: risk of ble
q 4 to 6 hours as needed cerebrovascular bleeding, thrombocytopenia prophylac
(not to exceed 40 mg/day or hemorrhagic diathesis, Skin: rash, pruritus, before sur
5 days). incomplete hemostasis diaphoresis
Children ages 2 to 16: 1 ● Prophylactic use before Other: excessive
mg/kg I.M. as a single dose, major surgery, intraoperative thirst, edema,
to a maximum of 30 mg; or use when hemostasis is injection site pain
one dose of 0.5 mg/kg I.V., critical
to a maximum of 15 mg ● Labor and delivery
➣ Ocular itching caused by ● Breastfeeding
seasonal allergic
conjunctivitis
Adults and children ages 3
and older: One drop of 0.5%
ophthalmic solution (Acular)
instilled into affected eye
q.i.d.
➣ Postoperative ocular
inflammation related to
cataract extraction
Adults and children ages 3
and older: One drop of 0.5%
ophthalmic solution (Acular)
instilled into operative eye
 q.i.d., starting 24 hours after
surgery and continuing for 2
weeks
➣ To reduce ocular pain,
burning, or stinging after
corneal refractive surgery
Adults and children ages 3
and older: One drop of 0.4%
ophthalmic solution (Acular
LS) instilled into operative
eye q.i.d. for up to 4 days
OMEPRAZOLE OMEPRON Reduces gastric acid ➣ Gastroesophageal reflux ● Hypersensitivity to drug or CNS: dizziness,  Assess Vit
secretion and disease its components headache, asthenia  Check for
increases gastric mucus Adults: 20 mg P.O. GI: nausea, abdomina
and bicarbonate (capsules, powder) daily for vomiting, diarrhea, emesis, Di
production, creating 4 weeks constipation, or constip
protective ➣ Erosive esophagitis abdominal pain  Evaluate fl
coating on gastric Adults: 20 mg P.O. Metabolic: intake
mucosa and easing (capsules, powder) hypomagnesemia  Watch for
discomfort from excess daily for 4 to 8 weeks Musculoskeletal: elevated l
gastric acid ➣ Short-term treatment of back pain; fractures function t
active duodenal ulcer of hip, wrist, spine results
Adults: 20 mg P.O. (with long-term  Tell patien
(capsules, powder) daily use) take 30-60
daily for 4 weeks. Some Respiratory: cough, minutes b
patients may need 4 upper respiratory meal, pref
additional weeks of therapy. tract infection in morning
➣ To reduce risk of Skin: rash  Instruct pa
duodenal ulcers caused by swallow ca
Helicobacter pylori or tablets
Adults: 40 mg P.O. and no to
 (capsules) daily in morning, crash them
given with clarithromycin  Caution pa
t.i.d. for 2 weeks; then 20 avoid driv
mg daily for 2 weeks other haza
➣ Gastric ulcers activities u
Adults: 40 mg P.O.(capsules) know drug
daily for 4 to 8 weeks concentra
➣ Pathologic and alertn
hypersecretory conditions,
including Zollinger-Ellison
syndrome
Adults: Initially, 60 mg P.O.
(capsules) daily; may
increase up to 120 mg t.i.d.
Divide daily dosages above
80 mg.
➣ Frequent heartburn (two
or more episodes a week)
Adults ages 18 and older:
20 mg P.O. (OTC tablets,
capsules, or powder) daily
for 14 days
RANITIDINE ZANTAC Competitive inhibition  Used to prevent  Hypersensitivity to • Constipation C - Gastointestinal
of histamine at H2 ulcer while patient is ranitidine or any • Diarrhea Antisecretory (H2-
receptors of the gastric on NPO component of the • Fatigue receptor antagoni
parietal cells, which formulation. • Headache H - Reduced amou
inhibits gastric acid • Insomnia acid in the stomac
secretion, gastric • Muscle pain may result to prev
volume, and hydrogen • Nausea ulcer incidence.
ion concentration are E - Every 8 hours w
reduced. Does not patient is on NPO.
affect pepsin secretion, C - Instruct client t
pentagastrin stimulated report any adverse
intrinsic factor reaction to the ph
secretion, or serum or nurse. Tell patie
gastrin. antacids may decr
the absorption of
ranitidine.
K - Ranitidine can
interfere with the
metabolism of alco
Patients taking ran
who drink alcohol
have elevated bloo
alcohol level.