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A new direction to improve health

CATALOG

2020 Product Update


The Compass Program has added a
sugar/aspartame-free xylitol gum after
results experienced by Dr. Patrick during
the 2020 lockdown, in which she was
unable to visit her dentist to address a
cavity.

During this time Dr. Patrick used the Xylitol


gum, and due to the length of the lockdown
she used it daily.

After the lockdown Dr. Patrick visited her


dentist and learned that the cavity identified
before the lockdown began, had diminshed
and as of this writing is no longer an issue.

Dr. Patrick attributes her dental recuperation


to the use of the Xylitol gum and
recommends it to those who would like to
maintain control of the dental health.

The Compass Participants should


experience the similar results with this
natural and useful product from the catalog.
Xylitol Boosts Dental Health

Many dentists recommend using xylitol-sweetened chewing gum — and for good
reason.

Studies have determined that xylitol boosts dental health and helps prevent tooth decay
(10Trusted Source).

One of the leading risk factors for tooth decay is an oral bacteria called Streptococcus
mutans. This is the bacteria most responsible for plaque.

Although some plaque on your teeth is normal, excess plaque encourages your immune
system to attack the bacteria in it. This can lead to inflammatory gum diseases like
gingivitis.

These oral bacteria feed on glucose from food, but they can not use xylitol. As such,
replacing sugar with xylitol reduces the available fuel for the harmful bacteria (11Trusted
Source).

While these bacteria cannot use xylitol for fuel, they still ingest it. After absorbing xylitol,
they are unable to take up glucose — meaning that their energy-producing pathway is
clogged and they end up dying.

In other words, when you chew gum with xylitol or use it as a sweetener, the harmful
bacteria in your mouth starve to death (12Trusted Source).

In one study, xylitol-sweetened chewing gum reduced levels of bad bacteria by 27–
75%, while friendly bacteria levels remained constant (13Trusted Source).

Animal studies also suggest that xylitol may increase absorption of calcium in your
digestive system, protecting against osteoporosis and strengthening your teeth
(14Trusted Source, 15Trusted Source).

Human studies demonstrate that xylitol — either by replacing sugar or adding it into
your diet — can reduce cavities and tooth decay by 30–85% (16Trusted Source,
17Trusted Source, 18Trusted Source).

Because inflammation is at the root of many chronic diseases, reducing plaque and
gum inflammation could have benefits for the rest of your body as well.

Summary Xylitol can starve the harmful bacteria in your mouth, reducing plaque
buildup and tooth decay. This can help prevent dental cavities and inflammatory gum
diseases.
Hydrogen Water
The Compass Program has acquired personal Hydrogen Water Generators that are
simple to use and maintain. The purpose of the Hydrogen Water Generator allows
Compass Participants to use the Hydrogen Water produced to increase the level of
alkalinity in the body.

4-10 minutes after Hydrogen water is produced and consumed, the Hydrogenated
Water will increase alkalinity (between .8 to 1.2+), within the body. This allows users to
check their PH levels to achieve an optimum condition of alkalinity, and thus pro-actively
control their ideal PH levels.
Reishi Mushroom

Canister purchases require 7-10 days for delivery


Background:

The Compass Program is the result of research, with contributions from hard-disciplines that could
provide insight on the question of aging.

How, and when does it begin, and what resources of past and present knowledge could be used to
provide answers to improve health changes in the latter years of life.

The important consensus among the participants was that hallmark changes are recognized when the
aging process begins, and generally in the 5th decade of life. The changes can be noticeable, such as the
graying of hair (non-premature), elasticity of skin, vision declination, and lack of energy.

Good health, food and genetics contribute to a delay of the effects of aging, and poor health can be
attributed to the mechanisms' of the body's ability to repair itself.

The Compass Research focused on cell replication at the molecular level and the following references
will allow everyone to understand the complex processes that contribute to aging and the decline of
health.

Synopsis:

The program was formulated to provide a nutrients program to a the body for its use-needs, and since
there is a limited amount of recognized research on studies to evaluate their affect/effects on body
physiology (See Appendix A).

The Compass Program:

The findings of the evaluation were developed in a methodology that supports the Hypothesis to
provide the elements, minerals, and elementary electrons that allow the mitochondria to repair or
replace cellular components (See Appendix B).
Hypothesis:

The outline of the Compass research is to identify natural sources that provide the mitochondria of the
body, the necessary elements to repair or replace cellular components in the body.

1. The electron pathway connects the energy source mitochondria requires.

2. The mitochondria uses the energy and elements to repair or replace cells (See Appendix C).

3. The study of the mechanism that contributes to cellular aging and a potential marker of cellular
disease (See Appendix A).

4. The public has a large selection of products and practices that have been available for decades with
minimal research to evaluate efficacy at the cellular level *.

5. The agriculture and food industry are providing products that when purchased by the consumer, are
presumed to provide the necessary nutrients to the body*.

Sources:

a. The preceding and current food production-supplement market, practices, product focus, and sales*.

b. NIH, PLOS, and other recognized journals on human physiology, and cellular disciplines, in re.,
agricultural practices-distribution, supplement references, studies, research, and trials *.

*Information, and methodology is provided to Compass Program participants.

Note: Multiple hard disciplines were required including; chemical-molecular, biology-chemistry,


agronomy, and a compendium of of exact, natural, economic and social sciences on practices to
understand agriculture.

Appendix A:

The National Institute of Health has released the findings that confirms the presence of senescent cells.

Appendix B:

Shilajit is a product of Humic Shale used for thousands of years in Eastern medicine. The research
revealed a high-concentration of active septuagenarians, and octogenarians in one of the harshest
regions in the world. Investigation learned that many of the individuals, consumed a rare substance
daily, and believed that it contributed to their health and longevity.

Appendix C:

You, Me, and Energy is a lecture that provides information on the minerals and energy the body
requires.
Appendix A-Senloytics-NIH

This is news being shared as it provides a confirmation of senescence. The following is the academic
release and included in the general public release with highlights that point to the relevant statements
as follows:

1. The senescent cells cause physical dysfunction and contribute to decreased survival

2. Senescent cells have been found in diseased organs

3. Senescent cells introduce pro-inflammatory cytokines into the body environment

By recognizing the need of our bodies at the cellular level and providing the essential nutrients and
electrons, many of the cells will have a resource to delay or the potential to prevent senescence.

https://www.nature.com/articles/s41591-018-0092-9

Senolytics improve physical function and


increase lifespan in old age
Nature Medicine (2018) |

Abstract
Physical function declines in old age, portending disability, increased health expenditures, and
mortality. Cellular senescence, leading to tissue dysfunction, may contribute to these
consequences of aging, but whether senescence can directly drive age-related pathology and be
therapeutically targeted is still unclear. Here we demonstrate that transplanting relatively small
numbers of senescent cells into young mice is sufficient to cause persistent physical dysfunction,
as well as to spread cellular senescence to host tissues. Transplanting even fewer senescent cells
had the same effect in older recipients and was accompanied by reduced survival, indicating the
potency of senescent cells in shortening health- and lifespan. The senolytic cocktail, dasatinib
plus quercetin, which causes selective elimination of senescent cells, decreased the number of
naturally occurring senescent cells and their secretion of frailty-related proinflammatory
cytokines in explants of human adipose tissue. Moreover, intermittent oral administration of
senolytics to both senescent cell–transplanted young mice and naturally aged mice alleviated
physical dysfunction and increased post-treatment survival by 36% while reducing mortality
hazard to 65%. Our study provides proof-of-concept evidence that senescent cells can cause
physical dysfunction and decreased survival even in young mice, while senolytics can enhance
remaining health- and lifespan in old mice.

Appendix A-Senloytics-NIH
Appendix A-Senloytics-NIH

Senolytic Drugs Reverse Damage Caused by


Aging Cells in Mice
NIH-funded researchers see extended health span and life span in treated mice

Injecting senescent cells into young mice results in a loss of health and function but treating the mice with
a combination of two existing drugs cleared the senescent cells from tissues and restored physical
function. The drugs also extended both life span and health span in naturally aging mice, according to a
new study in Nature Medicine, published on July 9, 2018. The research was supported primarily by the
National Institute on Aging (NIA), part of the National Institutes of Health (NIH).

A research team led by James L. Kirkland, M.D., Ph.D., of the Mayo Clinic in Rochester, Minnesota,
found that injecting even a small number of senescent cells into young, healthy mice causes damage that
can result in physical dysfunction. The researchers also found that treatment with a combination of
dasatinib and quercetin could prevent cell damage, delay physical dysfunction, and, when used in
naturally aging mice, extend their life span.

“This study provides compelling evidence that targeting a fundamental aging process—in this case, cell
senescence in mice—can delay age-related conditions, resulting in better health and longer life,” said NIA
Director Richard J. Hodes, M.D. “This study also shows the value of investigating biological mechanisms
which may lead to better understanding of the aging process.”

Many normal cells continuously grow, die, and replicate. Cell senescence is a process in which cells lose
function, including the ability to divide and replicate, but are resistant to cell death. Such cells have been
shown to affect neighboring ones because they secrete several pro-inflammatory and tissue remodeling
molecules. Senescent cells increase in many tissues with aging; they also occur in organs associated with
many chronic diseases and after radiation or chemotherapy

Senolytics are a class of drugs that selectively eliminate senescent cells. In this study, Kirkland’s team
used a combination of dasatinib and quercetin (D+Q) to test whether this senolytic combination could
slow physical dysfunction caused by senescent cells. Dasatinib is used to treat some forms of leukemia;
quercetin is a plant flavanol found in some fruits and vegetables.

To determine whether senescent cells caused physical dysfunction, the researchers first injected young
(four-month-old) mice with either senescent (SEN) cells or non-senescent control (CON) cells. As early
as two weeks after transplantation, the SEN mice showed impaired physical

function as determined by maximum walking speed, muscle strength, physical endurance, daily activity,
food intake, and body weight. In addition, the researchers saw increased numbers of

Appendix A-Senloytics-NIH
Appendix A-Senloytics-NIH

senescent cells, beyond what was injected, suggesting a propagation of the senescence effect into
neighboring cells.

To then analyze whether a senolytic compound could stop or delay physical dysfunction, researchers
treated both SEN and CON mice for three days with the D+Q compound mix. They found that D+Q
selectively killed senescent cells and slowed the deterioration in walking speed, endurance, and grip
strength in the SEN mice.

In addition to young mice injected with senescent cells, the researchers also tested older (20-month-old),
non-transplanted mice with D+Q intermittently for 4 months. D+Q alleviated normal age-related physical
dysfunction, resulting in higher walking speed, treadmill endurance, grip strength, and daily activity.

Finally, the researchers found that treating very old (24- to 27-month-old) mice with D+Q biweekly led to
a 36 percent higher average post-treatment life span and lower mortality hazard than control mice. This
indicates that senolytics can reduce risk of death in old mice.

“This is exciting research,” said Felipe Sierra, Ph.D., director of NIA’s Division of Aging Biology. “This
study clearly demonstrates that senolytics can relieve physical dysfunction in mice. Additional research
will be necessary to determine if compounds, like the one used in this study, are safe and effective in
clinical trials with people.”

The researchers noted that current and future preclinical studies may show that senolytics could be used to
enhance life span not only in older people, but also in cancer survivors treated with senescence-inducing
radiation or chemotherapy and people with a range of senescence-associated chronic diseases.

This press release describes a basic research finding. Basic research increases our understanding of
human behavior and biology, which is foundational to advancing new and better ways to prevent,
diagnose, and treat disease. Science is an unpredictable and incremental process—each research advance
builds on past discoveries, often in unexpected ways. Most clinical advances would not be possible
without the knowledge of fundamental basic research.

Contacts and sources:


Barbara Cire
NIH/National Institute on Aging

Citation: Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N. Farr, Bettina M. Weigand, Allyson K. Palmer, Megan M. Weivoda, Christina L. Inman, Mikolaj B.
Ogrodnik, Christine M. Hachfeld, Daniel G. Fraser, Jennifer L. Onken, Kurt O. Johnson, Grace C. Verzosa, Larissa G. P. Langhi, Moritz Weigl,
Nino Giorgadze, Nathan K. LeBrasseur, Jordan D. Miller, Diana Jurk, Ravinder J. Singh, David B. Allison, Keisuke Ejima, Gene B. Hubbard,
Yuji Ikeno, Hajrunisa Cubro, Vesna D. Garovic, Xiaonan Hou, S. John Weroha, Paul D. Robbins, Laura J. Niedernhofer, Sundeep Khosla,
Tamara Tchkonia, James L. Kirkland. Nature Medicine, 2018; DOI: 10.1038/s41591-018-0092-9

Appendix A-Senloytics-NIH
APPENDIX B-Shilajit-Background Information

Shilajit

Health is undeniably the most precious asset one can have. Ironically, maintaining a healthy body can be very
difficult in the modern day world. With a colossal rise in pollution and a far from ideal lifestyle, you need all
the help you can get to stay healthy. There are many supplements on the market that claim to help in
maintaining good health. None of them is as potent and effective as a resin collected in Siberia; Caucasus and
Himalayas called Shilajit or Mumie, in English known as mineral pitch resin. It is one of the rarest substances
on Earth and is proven to boost your overall health and vitality.

Shilajit has been used in the traditional Eastern medicine for centuries. The earliest reported usage of Shilajit
dates back as far as 4000 years in the ancient texts of Ayurveda.

What is Shilajit?
Shilajit is a brownish plant based organic material that oozes out of the rocks in the mountains of specific
mountain ranges. It is composed of organic plant matter compressed between the layers of rock, sealed away
from the atmosphere, for many years. It is collected by scraping the resin like substance from the dangerous
slopes of the mountains which make it extremely rare and expensive.

Shilajit is packed with minerals and trace elements. It is also very rich in some of the most potent
antioxidants, essential nutrients and other metabolites from plant sources.

The active ingredient of Shilajit or Mumie is a compound called ashless humic acid; it carries a molecule
known as dybenzo-alpha-pyrones. It is one of the most biologically potent substances found on earth.
Unfortunately, marketers often spike “shilajit” imitation with fulvic acid, which is a common fertilizer in
agriculture. The supersize mentality claims very high of fulvic acid, which in reality has nothing to do with
genuine mineral pitch with all the health benefits it offers.

Health benefits of Shilajit


Shilajit has numerous health benefits. In Soviet medicine known as mumie, it was regarded as a natural and
potent biogenic stimulator and adaptogen. In the traditional Indian medicine, it is seen as a “panacea,”
according to a 4000 treatise on health called Charaka Samhita. Some of the most important health benefits of
Shilajit include:

APPENDIX B-Shilajit-Background Information


APPENDIX B-Shilajit-Background Information

Antioxidant:
Shilajit effectively mimicks powerful antioxidants, capable of eliminating the dangerous free-radicals. It also
detoxified the blood and other tissues by scavenging and neutralizing non-healthy compounds.

Shilajit availability and counterfeiting


Being so potent and incredibly rare, Shilajit is very often counterfeited. It is available in the market in the
form of a powders, capsules, tinctures, form to be used as a supplement. Currently, even the resin form
counterfeits are on the rise.

However, over 99% of the products on the market are fake or substandard. Many of the products out there
either contain a very small amount of actual Shilajit or is not Shilajit at all.

As we saw earlier, the most potent ingredient in Shilajit is ashless humic acid, which are somewhat different
from fulvic acids. Fulvic acids are humic acids of lower molecular weight and higher oxygen content. Many
imitation Shilajit Supplements contain low-grade fulvic acid added to some powders that claim to be Shilajit.

Many so-called Shilajit powders are just dirt mixed with some fillers including fulvic acid. Many of these
products are not only ineffective but are quite dangerous as well. They contain a considerable amounts of
heavy metals such as Lead and Mercury that can be potentially harmful when ingested on a regular basis.

The most genuine form of Shilajit comes in the form of a resin. It is very dark brown in color and amount of
ashless humic acids ranges from 4-10%, and must be verified by numerous tests, which only a few companies
on the market are capable of properly doing. The naturally ashless humic acids are responsible for the health
benefits of Shilajit. It can not be supplemented with cheap versions of fulvic acids if you want the true health
benefits.

Hence, it is very crucial to choose the right form and quality of Shilajit if you want to see the benefits from its
consumption.

How to identify fake Shilajit?


Even though it takes a serious and qualified lab to identify high-quality mineral pitch resin for human
consumption (Shilajit, Mumie, Salajeet). Thre are some tests that you can conduct at your home, to test
whether the Shilajit is genuine or fake:

APPENDIX B-Shilajit-Background Information


APPENDIX B-Shilajit-Background Information

The best form of Shilajit is the resin form. If you hold the resin between the palms, it will soften due to the
warmth. However, if you store it in a freezer, it will harden substantially.

Genuine Shilajit dissolves almost completely in warm water and generates a dark golden to the reddish black
solution.

True Shilajit resin will not burn if ignited with a flame. It will bubble instead. At the high level of purity, it will
not smoke much or will barely smoke the white smoke, when highly contaminated resins smoke with darker
black smoke. Some imitation Shilajit resins are made with contaminants that will burn with a sooty flame
when ignited.

There are some fake Shilajit supplements out there. They are available in various forms including powders,
tinctures, and unfortunately even resins.

APPENDIX B-Shilajit-Background Information


Appendix B-Shilajit Analysis-6/2018

Appendix B-Shilajit Analysis-6/2018

*Program participants are provided a current stock analysis, and recommended practices for effective use
You, Me and Energy

We all have grown up with a concept of "body energy". Some of us bubble with energy, others
are "worn out". Moreover, from day to day we all experience fluctuations in our feeling of
"energy".

Newspapers and magazines are full of advertisements for "energy pills", "energy diets", "energy
courses" and you-name-it. The diet supplement industry is huge, the Internet full of endless links
and announcements aimed to get you to purchase something to make you less tired, stronger
and more enduring. With a "little help", you can become almost invincible without much extra
exercising. Glory is just a pill away... Or is it?

These pages are my effort to explain the origin of the energy that drives our bodies, that fuels
thoughts, movement, digestion, reproduction and growth; that is to say, all of our physical and
mental functions. This might appear to be a huge and complex undertaking but, as we will soon
see, the basics are really quite simple. You and I are driven by atomic energy!

What, atomic energy? Me?

Let me begin with a song that I have picked up from the Internet. It is one that I have valued
throughout my long
career. I have
always wanted to
include it in a lecture
but never had a
passing opportunity.
So, here comes
Michael Flanders and
Donald Swann with
"Thermal
Dynamics". Note
that they use "heat"
when they really
mean "energy". You
must click "back" to
return to this page
after playing the
song. Just click here
if you want to hear
this simple
explanation of what
energy is.

What are these Laws of Thermodynamics stated simply?

1
1. The first law of thermodynamics states that the universe's energy is
constant; it can neither be created nor destroyed.

2. The second law of thermodynamics states that energy can only be used
by moving it from a more active to a less active element.

What does this mean for you and me? Energy is all around us, it does not get "used up" when
we "do something". Energy merely moves from us to our environment when we "work". That is,
we "lose" energy as heat to our surroundings. All that "eating and breathing" only serves to move
energy to us. All that work just moves energy back to the environment.

The Atom and Energy


Now, what has this to do with running the human body on "atomic energy"? OK, let me explain
this. First we should look at a few atoms, especially those which are involved in our metabolism.
Those are mainly carbon,
oxygen and hydrogen.

Here are two drawings of


the carbon atom. They
show the general
construction of all atoms,
that is, particles with a
nucleus containing
protons and neutrons
surrounded by shells of
swarming electrons. The
carbon atom is made up
of 6 protons and 6
neutrons in the nucleus
and 6 orbiting electrons in
two surrounding shells.

What does the oxygen


atom look like? Well,
oxygen is a colorless gas
and carbon is a black
powder (or clear solid diamond!) so there must be huge differences in oxygen and carbon atoms.
Or...

In truth, the only difference between oxygen and carbon atoms is the number of the "sub-atomic"
particles in each of them. Oxygen has two more of every particle than carbon. Oxygen atoms
are made up of 8 protons, 8 neutrons and 8 electrons. Otherwise, carbon and oxygen they are
quite alike. In fact, the atoms of all of the widely differing elements found in nature differ only in
the numbers of protons, neutrons and electrons they are composed of. One exception is found;
hydrogen atoms are composed only of one electron and one proton. Hydrogen atoms do not
possess neutrons.

2
We can look at a more
modern presentation of an
atom in the next figure. Here
you can see that protons and
neutrons are made up of
smaller particles known as
several forms of "quarks". I
will not go further into this
except to point out that atoms
are quite unlike our common
mental picture of "good solid
matter".

I quote: "If we had


drawn the atom with
correct proportions and
the neutrons and protons
had a diameter of 10
centimeters:

1. The electrons and quarks would have a diameter of only 0.01 millimeter!

2. The atom would have had a diameter of 10 kilometers!

3. 99.999999999999 % of the atom is empty space"!

This is difficult to accept, but in fact, you and me, our cars, homes and the trees outside are
mostly empty space. Furthermore, those atoms that make us up abound with energy.

Nuclear Power
When we think of atomic
energy we usually associate
this with energy obtained from
the nucleus of unstable
atoms, usually uranium-235 or
uranium-239. When these
atoms adsorb neutrons they
split, producing smaller atoms
and releasing neutrons and
energy as gamma radiation.
The neutrons induce further
splitting of additional uranium
atoms with production of more
radiation and heat, the so-
called "chain reaction". By
controlling the stream of
neutrons we can manage the
rate of nuclear splitting and

3
heat production. The heat is trapped by warming up water and the steam produced drives
generators in much the same way as in coal or gas driven power plants.

The amount of energy stored in atomic nuclei is beyond our "normal" comprehension. An
example of this can be seen in atomic weapons. Uncontrolled nuclear division is the basis of
these. Release of the energy in around 2 - 4 kilograms of plutonium is equivalent to more than
10,000,000,000 kilograms of TNT. Happily, most atomic nuclei are stable and do not split and
release energy. But, that does not mean that the energy is lacking; it is just stable.

Now, this is NOT the energy that drives plants and animals and you and me. However, there is
another source of energy in atoms and that lies in the electron shells surrounding the nuclei.

Electron Energy
As I have shown you earlier,
atoms are comprised of a
nucleus surrounded by
electron shells. In the cases
of oxygen and carbon we
find two shells, in hydrogen
only one. A "filled" inner
shell or orbital contains 2
electrons, a filled second
shell contains 8 electrons.
These shells are
"energetic", that is, the
electrons are held in place
by energy. Moreover, the
further they are from the
central nucleus, the more
energy they carry.
Electrons can "hop" from
one atom to another. As
Flanders and Swann
explained, they always do
this by hopping from a
higher to a lower energy state unless they get external "help". That is, they move from a shell
further from a nucleus to one closer to the center of the "receiving" atom. The energy is released
as photons and we sense this as heat or light.

This "electron hopping" is the source for all of the energy used by living organisms. For almost all
forms of life, this arises from burning of carbon-based material in air or, more correctly, using the
oxygen in air to accept electrons from carbon compounds.

4
In the following figure you can
see how burning takes place.
Two elements are required; a
reducing agent that is oxidized
and an oxidizing agent that
becomes reduced. Reduction
means gaining electrons;
oxidation is loss of electrons.
Remember once more the
song "Thermal Dynamics".
Electrons always of
themselves go from a warmer
(higher energy level) to a
cooler (lower energy level).
That is, the initial elements in
a burning process contain
more energy than the
products. Furthermore, the
total amount of energy is
constant. So, if products of
combustion are less energy-
rich than the burning elements, some energy must have "escaped" to the environment.

Let us look at an example of this. The simplest possible carbon-hydrogen molecule is the gas
methane. This is composed
of 4 hydrogen atoms and one
carbon atom. In our model
this is the reducing agent or
"A". The oxidizing agent is
oxygen or "B". If we stick a
match or a spark into a
mixture of methane and
oxygen the former burns and
we get water and carbon
dioxide as products. In effect,
the hydrogen atoms hop off
the carbon in methane and
bind to the oxygen atoms.
The carbon also binds with
oxygen giving us stable, low
energy products.

5
We can look more closely and
see what is really happening.
As I mentioned above, the
second electron shell is full
when it contains 8 electrons.
Now, atoms are friendly types
and do not object to sharing
electrons with other atoms.
The "8-rule" simply states that
a shell is full when it
POSSESSES OR SHARES 8
electrons. When we add a
little energy (the spark of
burning match) to the oxygen-
methane mixture, we provide
enough energy to split the
oxygen molecule (O2) into two
oxygen atoms, each with only
6 electrons. By accepting 2
hydrogen atoms from
methane, the oxygen once again fills its outer electron shell. The electrons from the hydrogen
atoms in methane now reside in two water (H2O) molecules. The carbon joins up with 2 oxygen
molecules forming CO2. All of the atoms in water and carbon dioxide now have or share 8
electrons in their outer shells and are "relaxed and happy" and quite unreactive. The energy
"lost" to the environment can be seen and felt as light and heat from the flame.

The heat from burning material can be captured by heating


water to stream as you can see in the picture of the old-
fashioned locomotive. Remember, the real driving force here
is the energy released when electrons hop from one atom to
another. This is a form of "atomic energy", but not that we
usually associate with this terminology.

A more modern example of release and capture of electron


energy produced by combustion is shown in the next figure.
Here, gasoline is burned in
the cylinders of the car's
motor, the heat expands the gas produced and forces the pistons
downward. Again, the driving force here is "electron-hopping"
from a carbon-hydrogen complex to oxygen, and the products are
essentially CO2 and water.

6
What has all of this to do with you and me? The weight lifter here does not emit steam and has
no mechanical motor. Can
electron-hopping really be
driving him too. Well, he does
use oxygen and forms carbon
dioxide from the food he eats.

Our "daily bread", be it vegetables, meat, milk, beer or anything else is largely comprised of
carbon-based products. We "burn" these using oxygen from the atmosphere. In essence, we
carry out the same combustion process that we use to produce stream or hot gases in our
machines. The difference lies in the way we capture the released electron energy. In living
organisms that energy is secured in a material we call ATP or adenosine triphosphate. All life is
based on a process wherein
the energy stored in ATP is
released by splitting off a
phosphate group from ATP
and forming ADP or
adenosine diphosphate and
inorganic phosphate (Pi).
We shall look closer at this
soon but note here that our
bodies are driven by
capturing energy released
from electron shells during
combustion of carbon
material as ATP. Atomic
energy (read "electron
energy") is the power that
drives you, me, the dog and
the tomato!

7
Just what is ATP? The next figure shows the detailed structure of this energy-rich compound.
We can see that it contains a nitrogen base, adenine, a sugar, ribose and a chain of three
phosphate groups. The
phosphates are comprised of
a central phosphorus atom
and three oxygen atoms. The
second and third phosphate
groups are tightly grouped
and interfere with one
another. That is, the oxygen
atoms repel each other quite
energetically. And this means
that they harbor energy and
are rather unstable.

The terminal phosphate group can be split off from ATP forming ADP and inorganic phosphate.
These are less energetic than the mother compound, ATP. The energy that is released in this
process is used to drive the
many diverse processes in all
living organisms.

8
We can summarize this simply as shown in the next figure. The energy released by converting
ATP to ADP and inorganic phosphate is used by our bodies to drive all of our various activities,
both mental and physical.
The real source here is the
energy found in the carbon
atoms in our food and
electron-hopping from these
to oxygen found in air. This
combustion produces CO2
and water in the same manner
as burning coal, gas and oil in
ovens and machines. The
difference here is that instead
of using heat to increase
pressure in a gas or water, we
capture a good bit of energy in
ATP. The total ATP
concentration in most tissues
is around 5 millimoles/kg and
this is relatively constant.
Even extreme exertion does
not reduce ATP levels more
than about 20%.

Here are some amazing facts about ATP:

1. There are about 50 grams of ATP in the adult human body. This covers
approximately 5 minute's normal existence. We use about 40-60 kilograms
of ATP daily. That means that our ATP stores must be replaced around
1000 times each day,

2. ATP is formed through oxidation of carbon atoms from sugars, starch,


fat and proteins, that is, through electron migration from carbon to oxygen.

3. "Body energy" is equal to the speed of ATP synthesis.

4. ATP production is dependent upon good food, good circulation and lung
function and good physical condition.

9
Electrons Can Capture and Store Energy; the
Carbon Cycle.
Thus far, I have taken up use
of energy released by electron
movement from high to low
energy states. However, it is
quite clear that there must be
a method to capture energy
and renew our sources of
high-energy electrons. The
basic process here is
movement of electrons back
from a low energy state to a
higher state. In other words,
we have to be able to move
"fallen" electrons back to
orbitals or shells further from
the atomic nucleus. And, in
fact, this is an important and
normal process. According to
"Thermal Dynamics",
electrons won't do this "of
themselves"; they need an
external source of energy.
What we need then is a system to capture energy from an outer source, and this is found in green
plants.

Green plants contain chlorophyll


and this pigment has the ability
to adsorb the energy of the sun.
Plants couple this to
photosynthesis, a process
involving splitting of water back
to oxygen and hydrogen and
capturing the adsorbed energy
as ATP. The ATP is utilized to
drive reduction of CO2 with
formation of new sugars and
starch. Thus, plants create food
for us from the waste products
of our metabolism and, in the
process, replace the oxygen we
use to metabolize foods. Note
that these synthetic processes
are completely dependent upon
solar energy. In the dark or
during periods with limited
growth, plants produce CO2 just
as you and me.

10
In summary, almost all life on earth is completely dependent upon the solar energy trapped by
green plants. They balance our carbon oxidation through reduction of the carbon dioxide we
form and convert this to the food we eat. In the process, they also produce the oxygen we are
completely dependent upon.
This is the carbon cycle and is
truly a wonder.

The Energy Content of Foods


The food we eat can be
divided up into several
classes; fats or lipids, sugars
and starch, proteins and
alcohols. These can give us
energy, usually measured in
calories per gram. It may be
surprising for some of you, but
these different foods contain
varying amounts of energy.
While fats yield 9 kilocalories /
gram, sugars and starch give
us a little less than half of this,
that is, 4 kilocalories / gram.
Proteins also give about 4
kilocalories / gram. Alcohol
yields 7,5 kilocalories / gram.
That means that a glass of
wine gives us as much energy
as double as much cola! Beer
and wine are major
contributors to the current global obesity epidemic.

11
What is the basis for these differences? Remember, the energy content of the food we eat is
directly related to "electron-hopping" from hydrogen-carbon complexes to oxygen atoms. Food
with many carbon-oxygen links can be said to be partially burned or oxidized before we eat it. It
contains fewer high-energy electrons and, therefore, less energy.

Now, just look at the figure. You will quickly see that fats contain mostly carbon-hydrogen bonds
and little oxygen. Fats or lipids are almost fully reduced and excellent donors of high-energy
electrons. The sugar (glucose) at the bottom of the figure contains many oxygen atoms and is
partially oxidized before being eaten. That means that it has fewer electrons to donate to oxygen
during metabolism and, therefore, gives us less energy than fats. Alcohol (ethanol) lies between
these in oxidation state and "energy content". It contains fewer hydrogen atoms and high-energy
electrons per molecule than fats, but more than sugars.

We have Two Pathways of ATP Synthesis

I will remind my readers once again


that ATP levels in all tissues are
rather low, they are used rapidly,
and are replaced just about as fast
as they are draw upon. This close
balance between synthesis and use
is achieved by utilizing the energy
released during oxidation of carbon
compounds and movement of
electrons from energy-rich shells to
shells with a lower energy content.
There is no other "form of magic"
here. Once more, work includes all
of our activities, both mental and
physical.

Let us go to the next figure and see


what kind of physiological reactions
drive ATP synthesis.

12
We have two possible routes
that produce ATP from ADP
and inorganic phosphate in
our bodies. The first is based
on partial oxidation of sugars
and is NOT directly dependent
upon oxygen. We call this the
anaerobic glycolytic pathway.
Here, sugars are converted to
lactic acid. We win two ATPs
for each sugar molecule that
goes through anaerobic
metabolism. Again, this is
"only burning" of the carbon
atoms in a sugar. The
product, lactic acid, still has
"electron-energy" and can be
further oxidized in the aerobic
pathway.

Note that only sugars can be


metabolized in this manner.

The metabolism of fats and proteins is locked to aerobic metabolism; that is, metabolism coupled
to reduction of oxygen with formation of CO2 and water. Here, oxidation of lactic acid from
anaerobic metabolism, fats and amino acids from digested proteins give a far greater ATP
production from each carbon atom that is oxidized. We generally say that we win 32 ATPs for
oxidation of six carbons in aerobic metabolism.

Now, that is a real difference! Why in the world do we use anaerobic metabolism at all? There
are two main reasons for this.

1. Some of our body tissues just do not have the capability to run aerobic metabolism; notably
blood cells.

2. Anaerobic metabolism is much faster than that oxygen-requiring aerobic pathway. We may
not get much ATP for each carbon that is oxidized, but this is an extremely rapid process.
Anaerobic metabolism may not be efficient and lactic acid does "hurt" when it builds up in our
muscles, but anaerobic ATP
production is high-speed.

Here is a table showing the differing


rates of synthesis of ATP from
various sources. I have not yet
discussed creatine phosphate but
can say that production of ATP from
this high-energy intermediate is the
most rapid of the ATP-producing
systems in our bodies. We can set
that rate to 100 so that we can
compare the rate of synthesis of
ATP from other substrates.

13
The next row shows the speed of ATP synthesis starting with sugar (blood glucose or sugar
stored as glycogen) and proceeding through anaerobic metabolism to lactic acid. The rate is
approximately one-half of that of synthesis from phosphocreatine.

The final two rows give you an idea about the rates of aerobic metabolism, first from sugar and
then from fat. Aerobic sugar oxidation goes only half as fast as anaerobic metabolism. Fats go
even slower since these must be released from adipose tissue, travel to muscles, and then be
activated and finally oxidized.

We can willingly call up these processes when we need them. Remember, phosphocreatine is
fastest, anaerobic sugar metabolism is fast but painful and exhausting, aerobic metabolism can
continue for long periods but gives a relatively slow ATP synthesis.

Here is a good example of these processes.

The skiers who are lying


and gasping came first over
the finish line. That final
sprint really took a lot of
ATP and called for a major
anaerobic sugar burning
with lactic acid production, a
fall in blood sugar levels
and, at the same time,
maximal aerobic
metabolism. We can just let
them lie there; they will be
ok soon.

The fellow standing there


came too late to the finish
line; he could have sprinted
even harder, used more
ATP, activated anaerobic
metabolism, become more
pooped and possibly won
the race.

Maybe those in the background are going on fat.

14
Muscle Composition Depends on Careful
Selection of Parents!
Our muscles are made up of several fiber types. Type I is predominately aerobic and exhibits
relatively slow contractions. Type IIB is mainly anaerobic has quick contractions. Type IIA has
an intermediate contractile rate and metabolism. The composition of an individual's muscles is
genetically determined and
permanent. We can train up
our bodies, improve
circulation and breathing and
build up muscle mass, but we
cannot alter the types of fibers
we have in our skeletal
muscles. People with a
predominance of those quick
IIB fibers can excel in
activities that demand
explosive reaction, for
example high-jumping,
sprinting or weight-lifting.
People with a dominance of
slow aerobic fibers make
excellent long-distance
runners. You must choose
your parents with care!

The figure shows sections of


human muscles which have
been stained to show which muscle types they are composed of. Quick anaerobic fibers are
dark; slow aerobic fibers are light-colored. Here you can easily see that the high-jumper's leg
musculature was dominated by quick anaerobic fibers. The marathon runner showed a
dominance of slower aerobic fibers.

The muscles of a high-jumper had a relatively low oxygen uptake, stored a lot of sugar as
glycogen, quickly produced lactic acid and exhibited rapid ATP synthesis over short periods.

The trained marathon runner had a relatively high oxygen uptake, a very well developed capillary
system, marked aerobic fat metabolism and produced a lot of ATP over long time intervals.

A high-jumper or sprinter cannot compete in and expect to win long distance events. A slim
marathon runner usually is no sprinter.

As a well-known Norwegian physiology professor used to say, "give me a muscle biopsy and I'll
tell you which event you should train for".

Cellular Energy Reserves and Osmolarity


ATP is the immediate source of energy that drives our physiological functions. However, as I
have explained, it is found in surprisingly small quantities in our tissues. Instead of storing ATP,

15
we store substrates for oxidation which can quickly be mobilized and "burned" to CO2 and water.
Once again, we utilize "electron energy" to drive our bodily functions. Why not just store ATP?
Why must we go through that burning process to replace ATP?

Our tissues are made up of cells and these are bounded with a thin so-called plasma
membrane. Salts and other water-soluble material can wander into our cells. In doing so, they
cause water to follow. A host of mechanisms that I will not discuss here selectively pump excess
material out of cells and tissues so that they maintain more-or-less constant physiological
concentrations. Cells and tissues are held "iso-osmotic" with an osmotic pressure of about 300
milliosmoles / liter.

Let us look at a model showing what happens if cells are exposed to alterations in osmotic
pressure. The figure shows
red blood cells and their
responses to increased and
decreased osmotic pressure.
The normal condition is shown
in the center. Here you can
see a balance in water flux in
and out of the cells. They
maintain a normal
configuration. To the left you
can see the result of removing
salts and water from these
cells. They collapse and
cease to function. Equally
destructive is an increase in
cell volume caused by a salt
and water influx as shown to
the right. The arrow points to
a cell ruptured by the
increasing pressure and
cellular expansion.

The point here is that we cannot store extra water-soluble material (for example ATP) as an
energy reserve. Instead, nature has equipped us with two substrates for energy metabolism
WHICH DO NOT DISTURB THE CELL'S OSMOTIC BALANCE. This follows two ingenious
mechanisms:

1. We store sugars as a polymeric macromolecule, glycogen, which is not


soluble. Instead, glycogen forms a surface in the cell's cytoplasm that adsorbs the enzymes
essential for its metabolism. Thus, glycogen can release glucose when needed without altering
the cell's osmotic pressure. This gives us a substrate for both anaerobic and aerobic energy
metabolism. Glycogen metabolism is hormone-controlled and coupled to our energy needs.
Glycogen stores are, however, somewhat limited. Driving anaerobic metabolism to its limits
initiates uptake of sugar from the blood and, eventually, loss of consciousness.

16
2. We store carbon as fat. We all have fat-storing tissues, adipose tissue. Normal slim
men store around seven
kilograms of fat, women
approximately 15 kilograms.
The big advantage of these
stores is that the fat lies
outside of the cell's cytoplasm
and is not water-soluble.
Again, hormone steering
controls fat metabolism such
that fat is built up and broken
down according to one's
energy intake and
expenditure.

I will point out once more, the


energy we use to drive our
body's functions comes from
"burning" sugars, fats and
proteins and by transferring
electrons from these to
oxygen. Electron-hopping
from high to low energy states drives the system, also when we use our energy reserves, fat and
glycogen.

Phosphocreatine, an Important Water-soluble


Energy Reserve
Phosphocreatine is one of our
most important energy
reserves, especially in skeletal
muscles. The figure shows its
structure and route of
synthesis. Phosphocreatine is
made from ATP by
transferring a high-energy
phosphate from ATP to
creatine. This allows us to
"stockpile" energy, usually
about two to three times the
level of ATP in skeletal
musculature. Thus, the
concentration of ATP is
around 5 millimoles/kilogram
while the concentration of
phosphocreatine lies between
18 and 20 millimoles/kilogram
muscle.

How do muscles utilize


phosphocreatine? Early work suggested that muscles might be able to use both ATP and

17
phosphocreatine directly to fuel contraction. However, in the 1960s, Professor Robert Davies at
the University of Pennsylvania clearly demonstrated that phosphocreatine is a "buffer" for ATP.
Its high energy phosphate group must be transferred back to ATP before it can be utilized as an
energy source.

We make approximately half of our body's creatine ourselves, the rest comes from food. The
osmotic pressure from phosphocreatine is included in the normal pressure in our tissues. Once
again, remember that our bodies carefully control the concentration of salts and other water-
soluble materials in tissues such that this lies around 300 milliosmoles / kilogram.

Thus far, I have described ATP as a "high-energy" compound. Actually, it is better described as
having an intermediate energy
level. There are several
normal high-energy
intermediates in our
metabolism that can transfer
energy to ADP and Pi and
induce formation of ATP. A
good example of these is
creatine phosphate. Creatine
phosphate has a "free energy
of hydrolysis" of -10.3 kcal /
mole; ATP has a "free energy
of hydrolysis" -7,5 kcal / mole.
This means that energy can
be transferred from creatine
phosphate to ATP. More
correctly, the energy-rich
phosphate group of creatine
phosphate can be transferred
to ADP with formation of ATP
and release of some heat.
ATP can transfer its phosphate group to less energetic compounds, for example blood sugar or
glucose, and form a sugar phosphate. Glucose phosphate has a "free energy of hydrolysis" of
3,3 kcal / mole. ATP has been described as the body's currency, serving to hand over energy
from one agent to another. Furthermore, as Flanders and Swann so correctly pointed out,
"energy can only of itself go from a "hotter" to a "cooler".

18
Why is phosphocreatine so important?

The answer is a question of timing. The next figure shows the sequential contribution of our four
energy sources for muscle contraction. These curves give you an idea about the onset and
duration of energy use from
ATP (yellow curve),
phosphocreatine (red curve),
anaerobic metabolism of
sugar (green curve) and
aerobic metabolism of sugar,
starch and fat (black curve).

Let us begin with ATP.


Remember, ATP levels are
relatively stable. A 20 % fall is
huge! Direct utilization of ATP
starts immediately at the
beginning of muscle
contraction but is balanced
very quickly through use of
phosphocreatine.

Phosphocreatine
(creatine phosphate) is
a buffer for ATP. It balances out ATP consumption rapidly. BUT, note that the limited
amount of phosphocreatine is used up within the first 60-90 seconds following initiation of muscle
work. Anaerobic metabolism of sugar (glucose and glycogen) starts up and peaks just after this
short period.

The importance of phosphocreatine lies in the fact that it bridges the delay between the end of the
direct ATP-driven contractile period and the start of anaerobic sugar-driven ATP synthesis. This
assures a constant energy supply during the first minutes of muscle activity.

Anaerobic sugar metabolism is a relatively ineffective and partial oxidation (burning if you
will) but goes forward with great speed. Sprinters use anaerobic metabolism to run 100 meters.
They do not even need to breath while running. The same explosive energy generation is used in
weight lifting and hopping. The time span where this can function is limited. A maximal
anaerobic exertion is limited to between two and three minutes.

Aerobic metabolism takes over after this period. Well-trained athletes with type I muscle
fibers can run for several hours, using ATP generated by complete oxidation of sugars and fat
through oxygen-linked processes. Keep in mind that anaerobic metabolism must be called upon
for "sprints to finish" as seen in the picture of the ski competition. We can run relatively slowly for
a long time using aerobic metabolism, but increasing speed requires the anaerobic use of
glucose with formation of lactic acid.

Note that there is a sliding conversion from one source of energy to another, thus maintaining
ATP formation and energy transfer at a more or less steady level during a work period.

19
How can I Feel Better and Increase Performance?
Let's first summarize all this business about energy.

1. The ultimate source of bioenergy (body energy if you will) is the energy of the electrons in the
carbon and hydrogen atoms found in our food. This is made available through reaction with
oxygen (oxidation or burning) leading finally to formation of carbon dioxide (CO2) and water.
These products are reduced back to edible substances (food) by plants using solar energy. We
have no other possibilities to obtain energy for our bodies.

2. We can oxidize carbon from food with or without direct use of oxygen. Anaerobic metabolism
is quite rapid, and can provide energy for musculature for short and intense periods of activity.
The partially oxidized sugar is converted to lactic acid which is then further oxidized later or in
other tissues. Most organs cannot cover their energy requirements through anaerobic
metabolism but must fully oxidize carbon to CO2 using oxygen and the aerobic pathway.
Anaerobic metabolism can only use glucose or glycogen (a stored glucose polymer) as substrate
and produces lactic acid. Much of the discomfort following intense activity is due to accumulation
of lactic acid.

We can press our bodies to continue to make use of the anaerobic pathway after our glycogen
reserves are exhausted. However, the carbon source in this situation is blood sugar which is the
brain's normal source of energy. Since skeletal muscles make up 40-50 % of the body and the
brain only about 1.5 %, the brain must lose in "competition" with muscles for the limited amount of
blood sugar. So, extensive anaerobic metabolism in musculature reduces energy supplies to the
brain with dizziness, temporary loss of sight (a so-called red-out) and eventually loss of
consciousness as a result.

3. Aerobic metabolism can fuel the body over long time periods. It uses all possible substrates,
especially lipids or fat. The aerobic pathway does not reduce blood sugar levels and interfere
with the brain's metabolism. However, aerobic metabolism is rather slow and the muscular
activity level supported is not equal to that of anaerobic metabolism. A sprint to finish activates
anaerobic metabolism in addition to aerobic activity.

4. The secret to good performance is to maintain or increase the rate of formation of ATP. We
can do this through:

a. Increasing storage of glucose as glycogen in the liver and in skeletal muscles. This is, in
fact, done rather easily. The body guards itself against glycogen depletion by increasing stores if
and when they are emptied. Muscle glycogen levels can be doubled for several days following a
hard workout. Liver stores are also approximately doubled after the are used up. A hard workout
several days before a competition gives us extra stored glucose when we meet for that contest.
Empting liver glycogen by eating a low carbohydrate diet a few days before a game will increase
liver glucose stores with ensuing improvement in the sugar reserves available to buffer blood
sugar. You can click here for more information concerning glycogen storage.

b. Energy release from the oxidation of carbon atoms is dependent upon good blood
circulation and good lung activity. Oxygen must come to our working tissues and CO2 must be
removed. Physical training through daily activity is our best approach to good heart and lung
function. I will take this up once more under the section about aging.

c. Humans can survive and live well on almost all natural diets, from the fat-rich Inuit diet, the
protein-rich hunter diet and the carbohydrate-rich diet common under agriculture. There does not
appear to be any special "secret diet" to make us perform "better". Good food, good daily

20
exercise and a normal body weight (BMI* around 20-25) give a satisfactory start for
physical activity.
2
BMI = Weight (kgs) / height (meters)

d. We can train up aerobic musculature. The ATP-producing activity of individual


muscle cells and the blood circulation around them is increased by physical training-only
up to a point. Overtraining can, in fact reduce muscle strength and the secret here for
normal physical levels includes a diet or quality supplement, rich in electrons such as
Humic Shale-will enhance daily activity, and improve the quality of life.

Once again, body energy is derived from the energy of electrons in the carbon and
hydrogen atoms in our food. Good food, good exercise and a sound life-style improves
endurance at all ages.
I wish to show one more cause of death for many persons and arranged these according to
the degree of training these persons had. The striking conclusion is that exercise and
physical training does, in fact, protect us against death from most common threats.
Well-trained persons are less vulnerable to hypertension, pulmonary disease, diabetes,
smoking, obesity and hyperlipemia.

Live Better, Have More Endurance to achieve a higher quality of life.

21
Hydrogen Water

There are over 700 studies on the


benefits of hydrogen (and hydrogen
water) that inspire us, and we’d like
to share a few of them with you
along with some specific articles.
These studies have been created
from third-party funding. Check out
some of the links below.

Keep in mind, it is extremely


important for you to understand that
while we absolutely believe that
everyone should be drinking
hydrogen enriched water, we in no
way make curative claims to any
specific disease or pathology.

These studies and articles are shared for educational purposes only. They are not shared to
indicate any outcome for anyone with a similar or same disease or pathology. The studies show
potential or possible outcomes. There are no protocols, drugs, natural methods, or techniques that
are 100% effective. Every individual is different and diseases are complex.

Cell signaling in your body plays a key role in regulating gene expression. We are not talking
eye color here — your genes do much more than dictate physical characteristics. Genes give life-
sustaining instructions to cells, and cells carry out those instructions to keep you alive and
healthy. As we age, cell communication breaks down, the signal weakens, and gene expression
can be disrupted. Regulating gene activity with hydro-oxygen molecules keeps cellular
communication strong.

Hydrogen gas is the smallest molecule in our universe. Scientific studies have shown hydrogen
gas and adequate hydration can support the availability of clean cellular energy which our body
requires for the proper function of tissues and organs. Within the body’s tissues and organs,
Nano hydrogen is small enough that it can penetrate deep into human cells where our
metabolism transforms the food we eat into cellular energy. At this cellular level, hydrogen gas
and purified water provide essential metabolic functions that power both our mind and physical
performance.
The human body naturally receives hydrogen gas from the microbial flora that reside within each
of us. These symbiotic microbes produce hydrogen gas as they help our bodies obtain nutrients
from the food we eat. The microbial-produced hydrogen gas is then absorbed into our
bloodstream where its biological benefits are carried throughout our body until we exhale this
gas as we breathe. HNEX™ is an efficient way to directly deliver hydrogen gas into your body.

Many of us are unintentionally filling our body with chemicals, toxins and the wrong foods
which lower our pH balance. This acidic pH results in oxygen deprivation at the cellular level.
This is the beginning of degenerative disease.

Normal cells create energy via aerobic (with oxygen) respiration. Alkaline cells are able to
absorb sufficient quantities of oxygen to support aerobic respiration. However, when cells
become more acidic, less oxygen is absorbed, and the cells begin to ferment glucose in order to
survive. This concept is essential to understand, because cancer cells thrive in an acidic,
anaerobic environment and don’t do very well in an aerobic, alkaline environment.

Hydrogen water may contain antioxidants. Antioxidants help prevent oxidative stress. This type
of stress comes from both normal body functions and external forces, including sun exposure and
industrial chemicals. Oxidative stress may lead to cancer and other diseases.

These preliminary studies also suggest hydrogen water may be anti-inflammatory, a quality that
may reduce the risk of heart disease and other life-threatening diseases.

Scientific Recognition of Hydrogen

Although the primary targets or exact biochemical mechanisms of hydrogen are still not fully
understood, the therapeutic effect in cells, tissues, humans, animals and even agricultural plants
is becoming widely accepted due to the now over 500 peer reviewed articles and the 1,600
researchers working on the medical effects of hydrogen.

Here are some useful links to peer-reviewed scientific articles on molecular hydrogen, research
collaboration and many educational articles on molecular hydrogen.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/30102387/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/160993/
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/22460088/
• Scientific Report | 4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495244/
• Scientific Report | 5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560203/

Modulate hormone balance to support vitality and wellness

• Scientific Report | 1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600250/


• Scientific Report | 2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178641/
• Scientific Report | 3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753184/
• Scientific Report | 4 https://pubmed.ncbi.nlm.nih.gov/28669654/
• Scientific Report | 5 https://pubmed.ncbi.nlm.nih.gov/28560519/
Help maintain a healthy inflammatory response antioxidant

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/32189665/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/32699287/
• Scientific Report | 3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988658/
• Scientific Report | 4 https://pubmed.ncbi.nlm.nih.gov/30127861/
• Scientific Report | 5 https://pubmed.ncbi.nlm.nih.gov/30243702/

Improve gut health and digestive enzyme production

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/22146004/


• Scientific Report | 2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297538/
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/25523462/
• Scientific Report | 4 https://pubmed.ncbi.nlm.nih.gov/23610159/
• Scientific Report | 5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799803/

Help maintain cardiovascular health and support arterial elasticity

• Scientific Report | 1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395574/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/30486243/
• Scientific Report | 3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434465/
• Scientific Report | 4 https://pubmed.ncbi.nlm.nih.gov/28474871/
• Scientific Report | 5 https://pubmed.ncbi.nlm.nih.gov/25295663/

Protect the Liver – Research has shown hydrogen water also significantly improved liver
function and reduced oxidative stress in patients with chronic hepatitis B.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/24127924/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/23682614%20
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/24127924%20

Protect the Heart – In diabetic mice, hydrogen water significantly improved heart health
and prevented heart disease. In the future, it could become a nutritional intervention for
preventing heart problems in people with diabetes.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/25979689%20

Helps Hearing Loss – Hearing loss often results from oxidative damage (due to aging, noise,
or drugs). Molecular hydrogen has been shown to protect the cells responsible for hearing
from this damage and increase their survival. In guinea pigs, hydrogen water prevented the
death of cells responsible for hearing after noise exposure. This research provides
indications that hydrogen water could potentially protect against hearing loss caused by
noise or other types of oxidative stress.
• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/19339905%20
• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/22387110%20
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/24945316%20

Protect the Eyes – Research has shown hydrogen-loaded eye drops aided the recovery of
eye injuries caused by high eye pressure in rats. This protection of the eye nerves resulted
from the solution’s antioxidant action. This presents the future possibility that hydrogen
solutions could be used as a first-aid eye rinse to prevent blindness from chemical burns.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/19834032/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/20847117%20

Help Combat Allergies – There is a potential benefit for those who suffer allergies when they use
hydrogen water, which has been shown to help against allergies due to its antioxidant action. A study
has shown the benefits of hydrogen water in balancing the immune response for the common
inflammatory allergy condition, Eczema. In mice with eczema, hydrogen water improved symptoms by
suppressing inflammation and balancing both Th1 and Th2 responses.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/19766097%20


• Scientific Report | 2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852999/

Boosts Skin Health – Hydrogen water has been shown to help boost collagen production,
reduce UV damage and act as an antioxidant in skin cells. This shows the potential of
hydrogen water as a pleasant and safe way to reverse skin aging. The use of hydrogen
water improved skin health in patients with skin redness and inflammation/pain.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/22607973/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/22607973/

Diabetes Improvements Worth Knowing – Research has shown that drinking hydrogen
water decreased cholesterol, improved glucose tolerance and insulin resistance in a study
(DB-RCT) of 36 patients with type 2 diabetes or prediabetes (impaired glucose tolerance).
The patients drank 900 mL of hydrogen water daily for 8 weeks. Although it may be a safe
way to reduce the risk of type 2 diabetes, drinking sufficient amounts of regular water
alone may be helpful enough. Low water intake is linked to an increased risk of high blood
sugar.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/19083400%20


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/21994426%20

Boosting Weight Loss – Studies have shown that long-term drinking of hydrogen water
helped lose body fat and weight in rats. It boosted burning fats and sugars for energy,
without any change in diet. In fact, drinking hydrogen water had similar effects on the
body as did calorie restriction.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/21293445%20


Athletic & Muscle Performance – In an experiment with 10 young athletes (DB-CT),
drinking hydrogen water reduced lactic acid build-up during heavy exercise and decreased
muscle fatigue. Drinking 2 L of hydrogen water daily helped 8 cyclists power through
sprints with more energy and less exhaustion in one small 2-week study. In a study on mice
with a serious muscle-wasting disease (Duchenne muscular dystrophy), hydrogen water
prevented abnormal body mass gain and increased the production of the antioxidant
glutathione peroxidase. Hydrogen water could potentially improve muscular dystrophy in
DMD patients.

• Scientific Report | 1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395574/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/28474871/
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/26866650/

Suppressing Inflammation – In one pilot study, 20 patients with rheumatoid arthritis


drank 0.5 L/day of hydrogen water for 4 weeks. By the end of the study, all patients with
early rheumatoid arthritis achieved remission and 20% became symptom-free. Molecular
hydrogen (H2) also had anti-inflammatory effects in many animal studies.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/23031079/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/23859555/
• Scientific Report | 3 https://pubmed.ncbi.nlm.nih.gov/11510417/

Mood Disorders – Scientific research showed hydrogen water restored the natural growth
of brain cells in mice. Since this also happens in people who overcome depression (with
antidepressants or otherwise), hydrogen water has the potential for improving depression
and other mood disorders.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/18563058/


• Scientific Report | 2 https://pubmed.ncbi.nlm.nih.gov/24478038%20

Antioxidant & Brain-Protective Effects – Infusing molecular hydrogen into water has been
shown to act by reducing the most toxic reactive oxygen species (ROS) which protects the
cells from damage. A pilot study of 38 stroke patients showed that hydrogen water was safe
and had a mild antioxidant effect.

• Scientific Report | 1 https://pubmed.ncbi.nlm.nih.gov/17486089/


• Scientific Report | 2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694409/
• Scientific Report | 3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865993/

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