RLAN3 DATA B.

NO :AFOH010101
Time Temperature(℃)
S.No Op.No Description
Duration (Hrs) min. max.
1 18 Heat the solution to 45℃ to 50℃ 1:45 30.21 46.61
Stir the reaction mass for 15 to 20 min. at 45℃
2 19 0:20 46.61 48.13
to 50℃
Reciculate the reaction mass through Sparkler
3 20 0:20 NA NA
filter to get clear solution
Transfer the mass through Sparkler filter
followed by candy and micron filter NMT
4 21 2:30 NA NA
3Hours 30Minutes

Charge 160 L of FUR Lot-2 into Reactor and

5 26 0:25 45.3 48.13
heat to 45℃ to 50℃
Transfer FUR Lot-2 through Sparkler filter
6 27 followed by candy and micron filter at 45℃ to 0:37 48.13 49.85
50℃
7 28 Cool the reaction mass to 20℃ to 30℃ 10:15 35.78 21.7
Tranfer the Purified water Lot-1 through Micron
8 36 0:53 23.62 29.8
filter over period 45 to 60 min. at 20℃ to 30℃
Stir the mass at 20℃ to 30℃ for 30-45 min.
9 39 0:45 25.55 27.47
and chek for solid precipitation.
10 40 Cool the rection mass to 5 ℃ to 10℃ 4:45 7.52 25.55
Stir the rection mass at 5 ℃ to 10℃ for 1 to 2
11 41 2:00 7.83 7.22
hours
12 42 Apply NLT 600 mmhg vacuum to the PNF 0:18
Transfer the mass through PNF under vacuum
13 44 8:45
NLT600mmhg
Suck dry the wetcake under vacuum NLT600
14 45 1:35
mmhg till no flow of MLs observed
Charge 800 L of purified water Lot-2 into
15 46 0:45
thereactor in closed loop
Tranfer the Purified water Lot-2 through Micron
16 47 3:00
filter
17 48 Cool the purified water Lot-2 at 7℃-27℃ 1:10
18 62 Cgarge wet material into reactor 2:13
Charge 480 L of LMB Lot-1 into the charge
19 63 0:42
tank
20 64 Transfer LMB Lot-1 1:15
21 65 Stir the mass for 15 - 20 min. 0:15
22 66 Heat the reaction mass to 40℃ to 45℃ 2:50 27.07 41.85
Maintain the reaction mass at 40℃ to 45℃
23 67 1:00 41.85 43.07
for 45 to 60 min.
24 68 Cool the reaction mass to 5℃ to 10℃ 4:50 43.07 8.84
Maintain the reaction mass at 5℃ to 10℃ for
25 69 3:00 8.84 5.19
2hr 30 min. to 3 hrs
26 71 Apply NLT 600 mmhg vacuum to the PNF 0:35
Filter the mass through PNF under vacuum
27 72 8:20
NLT600mmhg
 Charge 160 L of LMB Lot-1 into the charge
28 73 0:40
tank
29 74 Transfer LMB Lot-2 0:18
30 75 Cool the LMB to 5℃ to 10℃ 0:40 7.72 7.42
31 88 Cgarge wet material into reactor 1:03
Charge 480 L of LMB Lot-3 into the charge
32 89 0:26
tank
33 90 Transfer LMB Lot-3 0:20
34 91 Heat the reaction mass to 40℃ to 45℃ 1:20 18.15 42.46
Maintain the reaction mass at 40℃ to 45℃
35 92 1:00 42.46 44.28
for 45 to 60 min.
36 93 Cool the reaction mass to 5℃ to 10℃ 4:55 44.28 9.55
Maintain the reaction mass at 5℃ to 10℃ for
37 94 3:00 9.55 8.13
2hr 30 min. to 3 hrs
Charge 160 L of LMB Lot-1 into the charge
38 97 0:20
tank
39 98 Transfer LMB Lot-2 0:15
40 99 Cool the LMB to 5℃ to 10℃ 0:40 11.88 9.45
41 105 Unload the wet material 2:27
42 111 Load the wet material into RCVD 2:02
43 112 Apply vacuum to the RCVD at NLT650mmhg 0:45 NA NA
Heat the material under vacuum NLT650 mmhg
44 113 0:35 23.93 51.98
to 50℃ to 55℃
Dry the material for 8 hrs under vacuum
45 114 8:00 51.27 53.6
NLT650 mmhg to 50℃ to 55℃
Cool the RCVD temperature 25℃ to 35℃ and
46 115 1:50 33.45 52.59
release the vaccum by appling Nitrogen
47 119 Unload the Dry material 0:55 NA NA

RAW MATERIALS
S.No Op.No Raw material Name SAP CODE Units Quantity
1 16 RLAN2 200000566 KG 160
2 12 FUR Lot-1 100000326 L 1280
3 26 FUR Lot-2 100000326 L 160
4 13 Hyflow 100001239 KG 3.2
5 35 Purified Water NA L 2880
6 46 Purified Water NA L 800
7 63 Ethyl acetate (LMB) 100001006 L 480
8 73 Ethyl acetate (LMB) 100001006 L 160
9 89 Ethyl acetate (LMB) 100001006 L 480
10 97 Ethyl acetate (LMB) 100001006 L 160
NO :AFOH010101
Hot water tubTemperature
Remarks
min. max.
Hot water tub temp. should be maintained below
51.47 56.23
60℃
Hot water tub temp. should be maintained below
51.68 52.28
60℃

NA NA

NA NA

Hot water tub temp. should be maintained below

55.32 54.41
60℃

NA NA

NA NA

NA NA

NA NA Solid precipitation is OK
NA NA
NA NA
 Wet material Weight :116.65

1.1 mmhg 737.5 mmhg

737.5 mmhg 737.9 mmhg

728.5 mmhg 742.0 mmhg

740 mmhg 1.1 mmhg

LOD: 0.12% W/W; Water by KF:0.05% W/W;
NA NA
Dry Wt: 103.27 KG

Volumes
NA
8
1
0.02
18
5
3
1
3
1
 Time Temperature(℃)
S.No Op.No Description Duration
(Hrs) min. max.

1 18 Heat the solution to 45℃ to 50℃ 2:10 22.51 46.11

Stir the reaction mass for 15 to 20 min. at 45℃ to

2 19 0:20 46.11 47.02
50℃

Reciculate the reaction mass through Sparkler filter

3 20 0:20 NA NA
to get clear solution

Transfer the mass through Sparkler filter followed

4 21 by candy and micron filter NMT 3Hours 30Minutes 2:00 NA NA

Charge 160 L of FUR Lot-2 into Reactor and heat

5 26 0:25 46.61 47.73
to 45℃ to 50℃

Transfer FUR Lot-2 through Sparkler filter followed

6 27 0:25 45.8 46.61
by candy and micron filter at 45℃ to 50℃

7 34 Charge 320 L LMB Lot-1 into charge tank 0:20 NA NA

8 35 Tranfer the LMB Lot-1 through Micron filter 0:15 NA NA

9 36 Cool the reaction massat 20℃ to 30℃ 5:00 27.07 33.65

Charge 2880 L of purified water Lot-1 into the
10 37 6:30 NA NA
reactor
Tranfer the Purified water Lot-1 through Micron
11 38 0:52 23.62 27.07
filter over period 45 to 60 min. at 20℃ to 30℃

Stir the mass at 20℃ to 30℃ for 30-45 min. and

12 41 0:43 24.23 26.66
chek for solid precipitation.
13 42 Cool the rection mass to 5 ℃ to 10℃ 7:01 9.85 24.23
Stir the rection mass at 5 ℃ to 10℃ for 1 to 2
14 43 2:00 8.33 9.85
hours
15 45 Apply NLT 600 mmhg vacuum to the PNF 0:15
Transfer the mass through PNF under vacuum
16 46 6:34
NLT600mmhg
Suck dry the wetcake under vacuum NLT600
17 47 1:20
mmhg till no flow of MLs observed
Charge 800 L of purified water Lot-2 into thereactor
18 48 0:47
in closed loop
Tranfer the Purified water Lot-2 through Micron
19 49 0:31
filter
20 50 Cool the purified water Lot-2 at 7℃-27℃ 0:28 12.18 21.5
21 60 Unload the wet material
22 68 Load the wet material into RCVD 1:20
23 69 Apply vacuum to the RCVD at NLT650mmhg 1:14
Heat the material under vacuum NLT650 mmhg to
24 70 1:56 22.81 51.68
50℃ to 55℃
Dry the material for 8 hrs under vacuum NLT650
25 71 8:00 51.47 53.3
mmhg to 50℃ to 55℃
 Cool the RCVD temperature 25℃ to 35℃ and
26 72 0:35
release the vaccum by appling Nitrogen

27 76 Unload the Dry material 2:42

Hot water tubTemperature
Remarks
min. max.
Hot water tub temp. should be
49.04 51.98
maintained below 60℃
Hot water tub temp. should be
49.35 49.75
maintained below 60℃

NA NA

NA NA

Hot water tub temp. should be

49.55 49.55
maintained below 60℃

NA NA

NA NA

NA NA

NA NA
NA NA

NA NA

NA NA Solid precipitation is OK

Wet material Weight :137.21 Kg

1.1mmhg 730mmhg
722.6mmhg 730mmhg

722.6mmhg 733mmhg
LOD: 0.08% W/W; Water by
KF:0.05% W/W; Dry Wt: 97.75
KG