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Sci10Q1L1L2: Molecular Biology and Mutation

Section 1  
General
MCQ

1. Once replication in a DNA molecule is complete, each new DNA molecule contains
________________.

A. two new strands 

B. 3  exact copies of strands 
C. one new strand and one old  Answer:
D. two old strands 

MCQ

2. Which of the following is NOT TRUE about the enzymes involved in DNA Replication?
 
E. Primase unzips the DNA stands by breaking the hydrogen bonds.
F. Ligase marks the point where the DNA Polymerase will start building.
G. Helicase glues the lagging stand together to create the new strand.

A. E and F 
B. F and G 
C. E and G  Answer:
D. E, F and G 

MCQ

3. Arrange the following sequences in correct order according to DNA Replication.

 
1. Topoisomerase keeps the DNA strands from supercoiling.
2. A certain enzyme unzips the DNA stands by breaking the hydrogen bonds.
3. A certain enzyme marks the point where DNA Polymerase with start building.
4. A certain enzyme glues the lagging strand together to create the new strand.
5. DNA Polymerase builds a complementary strand to each unzipped strand.

A. 1 - 3 - 2 - 5 - 4 
B. 1 - 2 - 3 - 5 - 4 
C. 2 - 1 - 5 - 3 - 4  Answer:
D. 1 - 2 - 3 - 4 - 5 

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MCQ

4. What is the process that copies information from DNA into RNA?

A. DNA transcription 
B. DNA translation  Answer:
C. DNA replication 

MCQ

5. Which of the following is TRUE about Okazaki fragments?

 
A. It is in the lagging strand.
B. It is in the leading strand.
C. It forms the old strand when glued together.
D. It forms the new strand when glued together.

A. A and C 
B. A and D 
C. B and C  Answer:
D. B and D 

MCQ

6.

 
What is the correct amino acid sequence for the mRNA code 5'AUGCCAGUAUGA3'?

A. Met - Pro - Ala - Val 

B. Met - Pro - Val 
C. Tyr - Gly - His  Answer:
D. Tyr - Gly - Arg - His 

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MCQ

7. Every three letters (example: ATC) in DNA codes for what?

A. Amino Acid 
B. Nucleotide 
C. Protein 
Answer:
D. RNA strand 

MCQ

8. The difference/s between DNA and RNA is that RNA __________________.

 
X. is single stranded
Y. contain the base Uracil
Z. can be transported outside the nucleus or via virus

A. X and Z 
B. Y and Z 
C. X and Y  Answer:
D. X, Y and Z 

MCQ

9. What will be the resulting mRNA from this DNA sequence:

5' GAT-TAC-AGA-TTA-CAT 3'?

A. 3' CTA-ATG-TCT-AAT-GTA 5' 

B. 3' CUA-AUG-UCU-AAU-GUA 5' 
C. 3' CAT-ACA-TAC-ATA-TAG 5'  Answer:
D. 3' GAU-UAG-UGA-UUA-GUT 5' 

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MCQ

10.

 
Which RNA is responsible for carrying amino acids to the ribosome? See figure above with
yellow labels. 

A. messenger RNA (mRNA) 

B. ribosomal RNA (rRNA)  Answer:
C. transfer RNA (tRNA) 

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MCQ

11.

 
The figure above shows which DNA process?

A. DNA Replication 
B. DNA Transcription  Answer:
C. DNA Translation 

MCQ

12. Which of the following codes is TRUE about the DNA strand undergoing DNA processes?
DNA Strand: 5' ATC-CCC-AGG 3'

A. complimentary strand: 3' UAG-GGG-UCC 5'   

B. mRNA: 3' TAG-GGG-TCC 5' 
C. anticodon: 5' AUC-CCC-AGG 3'  Answer:
D. amino acid combination: Met-Val-Pro 

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MCQ

13.

 
Which amino acid is translated from the RNA codon GUA with an anti-codon of CAU?

A. Histidine 
B. Aspartic Acid 
C. Leucine  Answer:
D. Valine 

MCQ

14.

 
What type of mutation is shown in the diagram?

A. Substitution Mutation 
B. Deletion Mutation  Answer:
C. Insertion Mutation 

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MCQ

15.

 
What type of mutation is shown in the diagram?

A. Insertion Mutation 
B. Deletion Mutation 
C. Substitution Mutation  Answer:
D. Inversion Mutation 

MCQ

16. Will there be an effect to the genes if the DNA codon mutated from AAT to AAC? Clue:
Transcribe and translate the DNA codon first. 

A. Yes (Missense Mutation)  Answer:

B. No (Nonsense Mutation) 

MCQ

17. TRUE or FALSE. The removal of three consecutive bases to the DNA sequence might lead
to a change on the succeeding (next) codons.

A. TRUE  Answer:
B. FALSE 

MCQ

18. Which of the following is/are TRUE about frameshift mutation?

 
1. Can only happen during deletion mutation.
2. It changes all of the codons from the mutation on down the line, which changes the amino
acid sequence.

A. 1 only 
B. 2 only 
C. 1 and 2 are true  Answer:
D. 1 and 2 are false 

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MCQ

19. Which among the following is a genetic mutation?

A. Translocation Mutation 
B. Inversion Mutation 
C. Duplication Mutation  Answer:
D. Deletion Mutation 

MCQ

20. Which among the following mutations is shown the figure below?

A. translocation 
B. inversion 
C. insertion  Answer:
D. substitution 

MCQ

21.

 
Which type of mutation caused the disease shown above?

A. deletion 
B. duplication 
C. inversion  Answer:
D. translocation 

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MCQ

22. Which type of mutation can cause unequal arm length to an individual? 

A. deletion 
B. inversion 
C. insertion  Answer:
D. duplication 

MCQ

23.

 
Which type of mutation can most likely cause the figure shown above? 

A. insertion 
B. duplication 
C. translocation  Answer:
D. inversion 

MCQ

24. DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTCGCAAG. 
 
This is an example of ___ mutation.

A. deletion 
B. insertion 
C. inversion  Answer:
D. substitution 

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MCQ

25.

 
Which type of mutation is shown in the figure above?

A. inversion 
B. deletion 
C. insertion  Answer:
D. duplication 

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