Professional Documents
Culture Documents
HOSPITAL
D/CM/18021/2142
JUNE, 2021
DECLARATION
I declare that this study is my original work and has never been presented for any award in
STUDENT
SUPERVISOR
i
DEDICATION
I wish to dedicate this document to my guardian for their encouragement and financial
ii
ACKNOWLEDGEMENT
My humble acknowledges goes to the almighty God, for the endurance, strength and whole
the good health bestowed to me. I also express my sincere and heartfelt gratitude to my
iii
ABSTRACT
Peptic ulcers according to Mayo Clinic definition, are open sores that develops on one’s
stomach along the lining and the upper portion of small intestine. This is brought about by
The ulcer is commonly caused by an infection with the bacterium helicobacter pylori and
long term use of non-steroidal anti-inflammatory drugs. Most studies has been on the
determinants of the causative agents of Peptic Ulcer Disease but little attention was on the
prevalence of the disease. Thus the reason this research was deal on the Prevalence of the
disease among adults aged 20-60. The study was conducted at Marigat Sub-County
Hospital.The objectives of the study were; to determine the knowledge of the people on
peptic ulcer disease, to determine the attitude of the people on peptic ulcer disease and to
questionnaires, this ensures relevant and reliable information is extracted from the potential
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Table of Contents
DECLARATION......................................................................................................................I
DEDICATION.........................................................................................................................II
ACKNOWLEDGEMENT....................................................................................................III
ABSTRACT............................................................................................................................IV
TABLE OF CONTENTS........................................................................................................V
CHAPTER ONE.......................................................................................................................1
BACKGROUND INFORMATION........................................................................................1
1.3 OBJECTIVES.....................................................................................................................4
CHAPTER TWO.....................................................................................................................5
LITERATURE REVIEW........................................................................................................5
2.2 ATTITUDE.........................................................................................................................6
2.3 PRACTICES.......................................................................................................................7
CHAPTER THREE...............................................................................................................10
METHODOLOGY.................................................................................................................10
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3.4 SAMPLING TECHNIQUE..................................................................................................11
CHAPTER FOUR..................................................................................................................14
4.1 INTRODUCTION..............................................................................................................14
4.2.2 Gender.....................................................................................................................15
4.2.3 Religion...................................................................................................................15
CHAPTER FIVE....................................................................................................................21
5.1 INTRODUCTION..............................................................................................................21
5.3 CONCLUSION.................................................................................................................22
vi
5.4. RECOMMENDATION..................................................................................................22
REFERENCE.........................................................................................................................23
APPENDICES........................................................................................................................25
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CHAPTER ONE: BACKGROUND INFORMATION
1.0 Introduction
Human body are becoming more susceptible to various diseases resulting from infections.
Peptic ulcers recently became a rampant infection which when not taken into consideration
Peptic ulcers are corrosions which affects ones stomach lining resulting to open sores that
develop till it eats up the lining. Also, the ulcers affects the upper portion of small intestine.
This is according to Mayo Clinic where they extended the infection to being caused by
(www.mayoclinic.org).
epithelial lining of the stomach. It is in form of an acid that corrodes the stomach then it
graduates to becoming sores (James K. Y. Hooi et al, 2017).The disease can be acute or
chronic and occurs as a result of weakening the defensive lining of the stomach. This defense
is aggregated by the presence of mucus in the lining and thus when the hydrochloric acid and
pepsin secretion occurs the mucus fails to defend and thus exposing the epithelium to the
acid.
H. Pylori has been a global problem with statistics showing the infection affecting about 50%
of the global population (M. Plummer et al, 2015). According to the study dubbed ‘Global
burden of gastric cancer attributable to Helicobacter pylori’; the diseases begins with
infection occurring during childhood and instills on one’s body for long term till adult hood.
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In USA, Peptic Ulcer Disease has been mapped as a disease that affect approximately 4.6
Million people annually and having about 10% estimates of evidenced ulcers of duodenal
In Nigeria, the prevalence of H. Pylori has notbeen properly established but with partial
studies, it has been established that the prevalence is high. This is asserted by facts of Bello K
et al (2019) Kano where the prevalence is at 81%, Jos, Also they reported reported at 87%
and south-West Nigeria, Muinah A. Et al (2017) reported 73%..More recent studies begin to
show similar prevalence rates for duodenal and gastric ulcers in both southern and northern
Nigeria was 25%; 11% had duodenal ulcers while 14% had gastric ulcers. Peptic ulcers
disease was higher among staff males and 36-40 years of age (Izuchukwu, 2015).
In Nakuru, between 2011-2013 study based at patterns of incidences of peptic ulcer disease in
(2019). Also, a research at St. Mary’s Hospital outpatient clinics, 1372 males and 1564
females showed 962 patients (33%) having gastritis, 280 patients (9.5%) have duodenal
ulcer and gastric ulcer with 54 patients (7.5%) (MakangaW ,Nyaoncha A, Jul 2014)
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1.1 Statement of the Problem
More than a half of the world´s population is estimated to be infected with Helicobacter
pylori (Hooi et al. 2017). During the study period of the scholar, they came out with a
projection where they predicted worse state to be experienced if no any intervention was
adopted.
Since inception and discovery of helicobacter pylori (H. pylori), various underlying factors
were blamed for development of Peptic Ulcers. These ranged from behavioral practices and
Today, Peptic ulcers are being blamed as silent causes of deaths. Mayo Clinic came up with a
causative agents of peptic ulcers to be the common Helicobacter pylori infection, non-steroid
alternative determinants of peptic ulcers have received limited attention in recent studies. A
lot of studies were dwelling on causes of Peptic Ulcers but less studies was on the continued
growth and prevalence of the disease. This prompted the researcher to get an urge to study
Prevalence of Peptic Ulcer Disease especially among adults between 20-60 years; as such
information could be prudent guide for decision making and development of prevention
strategies.
Among other stomach problems, ulcers have been a major problem commonly to the aged
group (over 20 years) that has been a major cause of death.Worldwide it has affected over
50% of global population (M. Plummer et al, 2015) thereby being a great public concern. In
Kenya healthcare has been having a flock recently with patients seeking advice and
3
Therefore, the study will provide a base line information to the stakeholders, government
hospitals, NGOs and other those who will have an interest on furthering studies on
1. The knowledge of early existence and causative agents of peptic ulcers will aid in
2. The research will be useful in identifying the magnitude of the problem and the
1.3 Objectives
To determine the prevalence of peptic ulcer disease among adults between 20-60 years
2. To determine the knowledge and attitude of the people on peptic ulcer disease
3. To identify social-economic and socio-cultural factors that cause peptic ulcer disease
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CHAPTER TWO: LITERATURE REVIEW
Knowledge regards soliciting general information the people have about the peptic ulcer
disease. On the course, these involve establishing the cause, risk factors, diagnosis, treatment
Ulcer tends to affect the entire gastrointestinal tract, starting from the lining of the mouth and
ending with the rectal region. The infection is associated with development that gradually
graduates to chronic gastritis and gastric cancer. Without treatment and better diagnosis, it
would definitely lead to death. Why would somebody die on an ailment that is known?
Becomes a question that answers a better extension of knowledge that should be instilled on
2015).
Through early detections, simple life style modifications and with the help of modern medical
treatment, the problem of peptic ulcer disease can be largely controlled and patients with
peptic ulcers can lead a prolonged and healthy life. Mere change of dietary or smoking habits
can reduce the problem of having peptic ulcers. And simple affordable treatment such as the
antimicrobial therapy for the eradication of helicobacter pylori can drastically reduce the
However, among at risk population, the current level of knowledge and behaviours and risk
perception are unknown. Studies show that knowledge about the helicobacter pylori;
interestingly those who have tested negative have more knowledge about helicobacter pylori
5
than those who have tested positive (Sung jj.2009). From the research conducted between
2005-2010 in USA, Most people think that mode of transmission of helicobacter pylori was
through water. From their sample size, 23% of the people answered helicobacter pylori can
In Nigeria, More recent studies begin to show similar prevalence rates for duodenal and
gastric ulcers in both southern and northern Nigeria was 25%; 11% had duodenal ulcers while
14% had gastric ulcers. Peptic ulcers disease was higher among staff males and 36-40 years
From the same study conducted in Nigeria, when their respondents were asked about where
they usually sought help when they have suspected Peptic Ulcer Disease, 50% claimed used
traditional healers, these depicted some form of informal setup the area was at.
In Kenya, the prevalence of peptic ulcer disease among Kenyans was ranging high with
regards to the symptoms, on endoscopy test, similar test showed from normal findings that
85% (2,081) patients. Gastritis was reported in 26% (1,560) patients, 10% (594) patients
having Duodenal ulcers and 5% (312) Patients have gastric ulcer. This number Makanga and
Nyaoncha (2014) continued by their research had not known how they acquired the infection.
And thus attestation of lack of knowledge can be attributed to the major cause of the peptic
ulcer was helicobacter pylori which was not known by most of the patients. (Makanga and
Nyaoncha, 2014)
2.2 Attitude
This involves provocative intention and feeling an individual has on or about Peptic Ulcer
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In Bangladesh, studies were done and asked questions regarding attitude related to
helicobacter pylori and peptic ulcer disease. All of the studies assessed perception of self-risk
of either contracting helicobacter pylori or developing peptic ulcer disease. Rafi A (2014)
found out that among patients attending Dhaka Medical College Hospital, most people of
cohort 15-45 years viewed their own risk as same or ‘lower’ when compared with people of
the same age and gender. This study further investigated own risk verses developing peptic
ulcer and from His finding, most people viewed their own risk for developing peptic ulcer as
average or low. Rafi A (2014) identified that 86% of people did not think they are affected
with helicobacter pylori despite that within this population prevalence was 40%.
In Nigeria, a study done on peptic ulcer perforation showed that the diseases perforation has
increased in prevalence. Okonkwo O et al (2018) found that the perforation of the gastric and
duodenum was as a result of peptic ulcer complication.it has been noted that most of the
population in area with peptic ulcers is related to non-steroidal anti-inflammatory drugs and
helicobacter pylori infection.it was found that most of the patient with the disease could
expect the disease to heal expecting that the disease would heal without such a complication
of perforation.
2.3 Practices
These are bound by deeds that forms day to day working of an individual. Internal organs
contributing factors of contraction of Peptic Ulcer Disease. He noted that Smoking claimed to
be a stronger risk factor for chronic ulcers than for new ulcers and it was reported that the risk
of Peptic Ulcer Disease increased as the amount smoked increased. From his sample, he
identified that among the male Peptic Ulcer patients male, 75% of them had smoked/are
7
smoking. These is substantial evidence that tobacco has causative agents for consideration.
Also, the study showed that NSAIDs are said to contribute to peptic ulcer formation by
undermining a vital part of the mucosal defensive forces. This corrodes and thereafter
exposing the epithelium for damage. Evidence that tobacco use is a risk factor for duodenal
ulcer is not conclusive. Support for a pathogenic role for smoking comes the finding that
disease showed relationship between prevalence of Peptic Ulcer Disease and Social
Economic Status, it was identified that a lower social economic status is associated with a
In such environment, hygienic observation and absorption is low owing the lack of
concentration due to pressure by the population. Such a condition impacts the kind of food
for uptake, how these food are handled and even to a greater extend the handlers of such food
Aziz Et al (2015) asked her respondents of their level of education as a demographic feature.
The results showed most respondents were of informal education with majority being up to
prevalence and the educational level of the population. Such environmental factors such as
general of hygiene, source of water supply and sanitation have been linked by the researcher
sampling it showed that infection was high on female having age more than 21 years,
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working as manual labourers. This spells the work they are subjected to that are strenuous
and demanding to the extent one may not get time or energy of preparing food to eat. And if
they find, the kind of food consumed may not be up to the standard that is required by the
body.
Also, along the study, the researchers connected large family size as associated with peptic
ulcer disease in adults. Such families are mind bungling which the body secretes hydrochloric
acid and thus impacting the mucosal membrane of the stomach lining thus popping up of
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CHAPTER THREE: METHODOLOGY
The study was conducted in Marigat Sub-County Referral hospital, found in Marigat Town of
Marigat is a fast-growing town located in the lowlands of Baringo County. It lies at 0.470 N,
35.980 E. Marigat Sub-County covers an area of 1,677.5 square kilometers and has a
The people are mainly pastoralists and subsistence peasant farmers. Also, the plains of the
sub-County favours bee keeping and wildlife keeping mainly the indigenous species.
In the County, the total number of health facilities is 227 comprising of 167 primary health
facilities. In Marigat Sub-County, Level 4 are 1, level 3 are 3, Level 2 are 18 and Level 1
facilities are 5 in Number. These in total are 27 Health Facilities in the Sub-County. (Baringo
A descriptive cross sectional study and probability sampling was used in finding answers to
the research questions. This design was adopted since it will ensure the target group are being
reached for study. Also, the design appropriately addresses the study objectives.
practices
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3.4 Sampling technique
Probability sampling method was used to ensure each unit of the sample is chosen so that all
units of study population should have an equal or known chance of being included in the
sample and Simple Random Sample was used to select the respondents.
Determination of the sample size was done using the Andrew Fisher method of 1994 for
Z 2 PQ
nf =
d2
N= Estimated population
Due to the sample being bigger Mugenda and Mugenda (2003) formula was adopted to
Nf=N
1+n/N
Where;
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Nf- 384
1+384/137
Nf=384
1+2.8
But due to limited time and financial constraints I was able to reach out to 30 respondents.
Inclusion criteria
All adults aged 20-60 who are willing to participate in the study and are attending Marigat
Sub-County Hospital
Exclusion Criteria
1. Adults aged 20-60 years who will not attend Marigat Sub-county Hospital
Dependent Variable
Independent Variable
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3.8 Data Collection Method
Researcher administered questionnaires to the respondents who were not able to read and
write and Self-administered questionnaires to the one who were able to read and write
The questionnaires were distributed in the Sub-County Hospital where the respondents were
able to fill by themselves but those who were not able they were assisted by the researcher.
The collected data was analysed using percentages by use of computer Package Excel. Data
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CHAPTER FOUR
4.1 Introduction
This chapter presents analysis and findings of the study as set in the research methodology.
The study aimed at investigating the factors determining prevalence of peptic ulcer disease
among adults aged between 20-60 years attending Marigat sub-county hospital. The
involved in the questionnaire and this was 100% response rates. Data analysis was done
The findings in Table 1 above indicated that prevalence of peptic ulcers is higher in adult
aged 31-40 and 41-50 and lower among adults aged 20-30 and 51-60
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4.2.2 Gender
The findings in Table 2 above indicated that prevalence of peptic ulcers is higher in female
than male
4.2.3 Religion
Majority of the adults in the village are Christians taking about 67% of the total respondents.
0% of the respondents were pagans. 33% declared that they are Muslims.
Table 4 above showed that the majority of the population are unaware of peptic ulcer disease
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Table 5 source of information on peptic ulcer disease
The table above indicated that majority of those who are informed about peptic ulcer disease
accessed information from health worker and the least from the internet.
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Section C:.Social Economic data
level of education
Axis Title
Column1
From the finding in bar graph above shows40% of the respondents reached primary
school,27% secondary level,23% collage level and 10% university level. This showed that
those who reached primary level of education as the most group with high prevalence of
peptic ulcer disease probably due to lack of knowledge about the disease.
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4.3.2.Distance to the nearest facility of the respondents
From the above finding it has showed that majority of the respondents 80% are able to access
health facility and only 17% a few move for a longer distance to get to a health facility.
percentage
yes no
The chart above shows that there is no cultural restriction on seeking for health services
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Food restriction by the culture
yes no
The above pie chart showed that 67% do not have food restriction to the culture and 33%
have food restriction in that majority of them take local brews(busaa,muratina and changaa).
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Section Social practices data
health facility; 50
tradional healer; 13
Column1
The above bar graph illustrates that 50% of the respondents seek health services on health
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CHAPTER FIVE: SUMMARY OF THE FINDINGS CONCLUSION AND
RECOMMENDATION
5.1 Introduction
This chapter presents the summary of the study findings, conclusion of the study and
recommendation drawn from the study. The purpose of the study was to investigate the
factors determining the prevalence of peptic ulcers among adults aged between 20-60 yearsin
Marigat sub-county hospital in Baringo county. This was to help determine the causes of
The study findings established that prevalence of peptic ulcers is higher in adult aged 31-40
and 41-50 and lower among adults aged 20-30 and 51-60 years with percentage of
respondents in percentage of 67%in female and 33% in male.Majority of the adults in the
village are Christians taking about 67% of the total respondents. 0% of the respondents were
The study observed that most of the respondents, 40% of the population are conversant of
peptic ulcer disease while 60% are not conversant. Majority of those who are informed about
peptic ulcer disease accessed information from health worker were 42% and the least from
the internet 8%. Therefore, there is need for health providers to give intensive health talks
The study findings established that 40% of the respondents reached primary school,27%
secondary level,23% collage level and 10% university level. This showed that those who
reached primary level of education as the most group with high prevalence of peptic ulcer
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disease probably due to lack of knowledge about the disease. Thus need for more health talk
According to the study findingsmajority of the respondents 83% are able to access health
facility and only 17% move for a longer distance to get to a health facility.There is no cultural
restriction on seeking for health services since 100% of the respondents attend to heath
facility when they are sick.The study established that that 67% do not have food restriction to
the culture and 33% have food restriction in that majority of them take local brews (busaa,
Also the study found that 50% of the respondents seek health services on health
5.3 CONCLUSION
The conclusion of this study is based on assumption that respondent’s response can be
generalized. The conclusion is that the prevalence of peptic ulcers is higher in adults aged
betwee20-40 years. However, females are more affected than male.it is evident that most of
the people don’t have knowledge about peptic ulcer in the area. also it was noted that cultural
practices and level of education contributed to the prevalence of the disease. Despite health
facilities are being accessible some people still opt for traditional healer and over the counter
5.4. Recommendation
There is need for health providers to give intensive health talks and sensitize clients about the
disease and this will help lower the prevalence of disease.
Health workers should follow up new clients to ensure complete eradication of the disease.
County government should enforce laws against illegal brews which are known to be risk
factor for the disease.
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REFERENCE
Aziz, R. K., Khalifa, M. M., and Sharaf, R. R. (2015) .“Contaminated water as a source of
Bello AK, Borodo MM, Yakasai AM, Tukur AD. Helicobacter pylori antibiotic sensitivity
pattern in dyspeptic patients in Kano, Nigeria. S Afr J Infect Dis. 2019;34(1), a125. https://
doi.org/10.4102/sajid. v34i1.125
James K.Y. Hooi Et al. 2017. “Global Prevalence of Helicobacter pylori Infection:
Javid G, Zargar SA et al, 2009. “Comparison of p.o. or i.v. proton pump inhibitors on 72-h
with Peptic Ulcers and the Associated Risk Factors in Mbagathi Level V Hospital, Nairobi
County, Kenya
with Peptic Ulcers and the Associated Risk Factors in Mbagathi Level V Hospital, Nairobi
County, Kenya
Counties, Kenya; a Two Year Comparative Endoscopy Study. July 2014. Volume II
Sung JJ, Kuipers EJ, EL-Serag HB 2009. Systematic review: the global incidence and
World J. Gastroenterol, 2019 Helicobacter pylori infection: Beyond Gastric Manifestation Jul
14; 25(26).
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APPENDICES
APPENDIX 1 : BUDGET
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Appendix II: Questionnaire
b) 31-40 years
c) 41-50 years
d) 51-60 years
d) Widowed ( ) e) Separated
d) University ( )
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9.What distance do you cover to your nearest health facility?
10.Does your culture restrict you from seeking health services from hospital?
a) Yes ( ) b) No ( )
If yes, explain
a) Yes ( ) b) No ( )
If yes, explain
a) Traditional healer ( )
b) Health facility ( )
d) Others (Specify)……………………………………………………….
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