Professional Documents
Culture Documents
Conditions
(OA, RA, AS)
Angela BM Tulaar
Definitions
Osteoarthritis Rheumatoid Arthritis Ankylosing Spondylitis
• A type of arthritis caused The most common form of • Ankylosing spondylitis (AS) is
by inflammation, inflammatory arthropaties a complex and debilitating
breakdown, and eventual and diagnosis is often disease with a worldwide
loss of cartilage in the difficult in the early stage. prevalence ranging up to
joints. Also known as 0.9%. 1 Its aetiology and
• Systemic Rheumatic
degenerative arthritis. pathogenesis are not yet fully
Disease as the result of understood, and its diagnosis
• degeneration of joint acute inflammatory
cartilage and the is difficult.
response
underlying bone, most • Involvement of the axial
common from middle age • Unknown aetiology skeleton, enthesopathy and
onward. It causes pain although the mechanism of extraarticular manifestations (
and stiffness, especially tissue damage is related to skin rashes,psoriasis, uveitis,
in the hip, knee, and immune system and aortitis)
thumb joints. mediators of inflammation
Osteoarthritis Rheumatoid Arthritis Ankylosing Spondylitis
OA Varians Types : • Ankylosing spondylitis (AS) is
• OA inflamatorik erosif • A self-limited Polyarthritis;
a complex and debilitating
• Ankylosing hyperostosis meets ACR criteria for RA on
disease with a worldwide
atau difuse presentation; no patients meet
criteria 2-5 yrs later
prevalence ranging up to
• idiopthatic skeletal 0.9%.1 Its aetiology and
hyperostosis (DISH) • Persistent disease;
management by conservative pathogenesis are not yet fully
• OA sekunder
treatment; few significant long understood, and its diagnosis
. is difficult.
term consequences
• Progressive disease with • Involvement of the axial
radiologic damage; functional skeleton, enthesopathy and
decline; premature morbidity extraarticular manifestations (
• Younger age of onset skin rashes,psoriasis, uveitis,
aortitis)
• Predominantly male
Sites of involvement
Delisa et al. Physical Medicine and Rehabilitation 4th edition Vol1. Lippincott Williams & Wilkins. 2005
Delisa et al. Physical Medicine and Rehabilitation 4th edition Vol1. Lippincott Williams & Wilkins. 2005
CLASSIFICATION CRITERIA FOR
OSTEOARTHRITIS OF THE HIP
• Hip pain
and
• At least two of the following three features:
- ESR = 20 mm/hour
- Radiographic femoral or acetabular
osteophytes
- Radiographic joint space narrowing
(superior, axial, and/or medial)
KRITERIA KLINIS OA LUTUT
(Altman. 1986)
NYERI LUTUT, ditambah salah satu dari :
1. Usia 50 tahun 6. Tidak teraba panas
2. Kekakuan 30 menit 7. Laju Endap Darah
40 mm/jam
3. Krepitus
8. Faktor Reumatoid
4. Nyeri tulang
1 : 40
5. Pembesaran tulang
9. Cairan sendi : OA
CRITERIA FOR CLASSIFICATION OF
OSTEOARTHRITIS (OA) OF THE KNEE
• Clinical and laboratory :
Knee pain plus at least five of nine:
- Age >50 years
- Stiffness <30 minutes
- Crepitus
- Bony tenderness
- Bony enlargement
- No palpable warmth SF OA
92% sensitive
- ESR <40 mm/hour 75% specific
- RF <1 : 40
CRITERIA FOR CLASSIFICATION OF
OSTEOARTHRITIS (OA) OF THE KNEE
• Clinical and radiographic :
Knee pain plus at least one of three:
- Age >50 years
- Stiffness <30 minutes
- Crepitus
+ 91% sensitive
- Osteophytes 86% specific
CRITERIA FOR CLASSIFICATION OF
OSTEOARTHRITIS (OA) OF THE KNEE
• Clinical* :
Knee pain plus at least three of six:
- Age >50 years
- Stiffness <30 minutes
- Crepitus
- Bony tenderness
95% sensitive
- Bony enlargement
69% specific
- No palpable warmth
Criteria diagnosis RA
(American College of Rheumatology, 1988) Dari 7 kriteria, diperlukan 4 untuk
menentukan diagnosis. Kriteria 1-4 harus didapatkan sekurangnya 6 minggu
http://en.wikipedia.org/wiki/File:Ankylosing_process.jpg
Classification of spondyloarthropathies using ESSG criteria
(European Spondylarthropathy Study Group )
Sensitivity 87%; specificity 87%.
Inflammatory spinal (back) pain
OR
Synovitis (asymmetric, predominantly in lower extremities)
PLUS at least one of the following:
Alternating buttock pain
Sacroiliitis
Heel pain (enthesitis)
Positive family history
Psoriasis
IBD (Inflammatory Bowel Disease ; Crohn’s disease, ulcerative colitis)
Urethritis/acute diarrhoea in preceding 4 weeks
Physical Examination
Osteoarthritis Rheumatoid Arthritis Ankylosing Spondylitis
• Observable signs of • Observable signs of • Observation on Posture
Inflammation and Inflammation and • Palpation of tenderness :
Deformities Deformities enthesis (tendons/ligaments)
• Palpable signs of • Palpable signs of • Limitation of movement (lumbar
inflammation, inflammation, spine)
Tenderness / Pain on Tenderness / Pain on
palpation and on palpation and on
movement movement • Bone mineral loss fracture
• Joint Range of Motion • Joint Range of Motion • Tiredness / Depression
• Muscle Strength • Muscle Strength • Breathing problems
• Special examinations on • Special examinations on
pertinent joints pertinent joints
Pemeriksaan Fisik: look
pembengkakan / swelling ; perubahan kulit
(kemerahan, psoriasis, fenomena Raynaud, tukak, ruam)
OA
SLE RA
Physical examination: look contractures /
muscle wasting around loints Deformities
swan-neck
deformity
hyperextension
PIP, flexion DIP
warm
Active ; Passive ;
tenderness Against resistance
Pemeriksaan fisik AS: harus mencakup ukuran
panjang tungkai dan penilaian kesimetrisan pelvis.
• Tiga atau lebih temuan positif pada tes provokasi 85% sensitif dan 79% spesifik
untuk penyakit sendi sakroiliak. Berbagai tes provokasi adalah : (Isaac)
Gaenslen test. Dengan pasien berbaring
terlentang, di dekat pinggiran meja periksa
dengan bokong sisi yang diperiksa pada pinggiran
meja periksa dan tungkai dijatuhkan sehingga
panggul dan paha dalam hiperekstensi. Lutut di
kontralateral difleksikan maksimal. Adanya Nyeri
atau tidak nyaman menyarankan suatu penyakit
sendi sakroiliaka, walaupun positif semu dapat terlihat pada pasien dengan lesi
akar saraf L2-4, spondilolisthesis, fraktur tulang sakrum, fraktur kompresi lumbal,
atau stenosis spinal.
2. Patrick test. Dengan pasien terlentang pada
permukaan yang rata, paha difleksikan dan
pergelangan kaki diletakkan di atas patela
tungkai yang lain yang dalam ekstensi.
Tekanan ke bawah pada lutut yang fleksi
bersamaan dengan tekanan pada spina iliaka
anterior superior sisi yang lain sambil posisi
kaki dipertahankan di atas lutut.
Nyeri atau tidak nyaman di daerah gluteus merefleksikan gangguan sakroiliaka, nyeri
di daerah selangkangan / paha menandakan gangguan sendi panggul.
Tes Provokasi : Tekanan pada Sulkus Sacrum. Aplikasi tekanan pada regio
gluteal yang menyebabkan nyeri daerah otot gluteus dapat
dipertimbangkan sebagai disfungsi sendi sakroiliaka. Tanda ini sering
ditemukan tetapi tidak spesifik, sering terlihat pada nyeri aksial diskogenik,
nyeri radikuler, fraktur sakrum, sindroma facet dan sindroma piriformis.
Distraction test Pasien berbaring terlentang,
(Gapping test).
diberi tekanan ke bawah dan
lateral pada kedua spina iliaka
anterior superior. Manuver ini
meregangkan ligamen
sakroiliaka ventral (depan) dan
simpai (kapsul) sendi serta
memberi tekanan pada ligamen
sakroiliaka dorsal.
Patellar grinding
Appley
Laksitas medio-
lateral
Drawer’s
Pergelangan kaki / Kaki
Schober test
Ankylosing Spondylitis:
Chest expansion
Pemeriksaan penunjang : foto polos
• Beratnya OA Panggul dapat dikategorisasi
berdasarkan sela sendi minimal (minimal joint space =
MJS) yaitu jarak terdekat pada foto polos antara tepi
kaput femur (femoral head margin) dan tepi
asetabulum (acetabular edge).
• MJS ditentukan oleh 4 (empat) pengukuran sela
sendi, dari medial, lateral, superior dan aksial.
• Gradasi MJS menurut Croft adalah :
0 = MJS > 2,5 mm;
1 = MJS >1,5mm dan 2,5mm;
2 = MJS 1,5mm.
(Reijman M, Hazes JM, Pols HA, et al. Validity and reliability of three definitions
of hip osteoarthritis: cross sectional and longitudinal approach.
Ann Rheum Dis 2004;63:1427-1433.)
To determine the progression of RA, patients are categorized by
clinical and radiologic criteria into 4 stages, as follows:
• Stage I (early RA) – No destructive changes observed upon
radiographic examination; radiographic evidence of osteoporosis is
possible
• Stage II (moderate progression) – Radiographic evidence of
periarticular osteoporosis, with or without slight subchondral bone
destruction; slight cartilage destruction is possible; joint mobility is
possibly limited, but no joint deformities are observed; adjacent
muscle atrophy is present; extra-articular soft tissue lesions (eg,
nodules and tenosynovitis) are possible
• Stage III (severe progression) – Radiographic evidence of cartilage
and bone destruction in addition to periarticular osteoporosis; joint
deformity (eg, subluxation, ulnar deviation, or hyperextension)
without fibrous or bony ankylosis; muscle atrophy is extensive; extra-
articular soft tissue lesions (eg, nodules, tenosynovitis) are possible
• Stage IV (terminal progression) – Presence of fibrous or bony
ankylosis, along with criteria of stage III
Rheumatoid
Arthritis
Normal
1 erosions
1 sclerosis
1 squaring
2 obvious
2 syndesmophytes
3 total bony
3 bridges
Delisa et al. Physical Medicine and Rehabilitation 4th edition Vol1. Lippincott Williams & Wilkins. 2005
Delisa et al. Physical Medicine and Rehabilitation 4th edition Vol1. Lippincott Williams & Wilkins. 2005
modalities
Exercises : Muscles, joints,
mobility, flexibility, etc
Exercise in Ankylosing spondylitis
Maintenance or improvement of
flexibility and mobility
Maintenance or improvement of muscle
strength and endurance
Maintenance or improvement of
coordination and balance
Maintenance or improvement of
cardiovascular & pulmonary fitness
Swimming is
one of the most
effective exercises
for ankylosing spondylitis :
strengthen muscles &
keep body supple;
increases lung capacity;
involves all muscles &
joints in a low gravity environment
General Guidelines