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1.

The skin consists of the following layers:


A. Basal, spinosum, granular, lucidum, corneum
B. Basal, spinosum, granular, corneum
C. Epidermis, dermis, hypodermis
D. Epidermis, dermis
E. Papillary, reticular

2. The skin appendages include:


A. Sweat and sebaceous glands
B. Nails, hair
C. Blood and lymphatic vessels, nerve endings
D. Nails, hair, sweat and sebaceous glands
E. Hair follicles

3. Terminal hair from root to outer end is formed from:


A. 1 layer
B. 1-2 layers
C. 5 layers
D. 3 layers
E. 4 layers

4. Sebaceous glands produce a secret:


A. Sebum
B. Slime
C. Sweat
D. Milk
E. Tears

5. By the nature of the secretion of sweat glands are: A. Holocrine


glands
B. Holocrine and apocrine glands
C. Eccrine and apocrine glands
D. Apocrine glands
E. Eccrine glands

6. The circulatory system of the skin forms:


A. Superficial and deep plexus
B. Superficial plexus
B. Deep plexus

7. Encapsulated skin receptors include:


A. Meissner corpuscle
B. Golgi corpuscle
W. Krause end bulb
G. Ruffini corpuscles and Vater-Pacini corpuscles
D. All answers are correct

8. How many phototypes of skin are distinguished according to the


Fitzpatrick classification?
A. 6
B. 3
C. 10
D. 5
E. 7

9. Collagen is produced by the following cells:


A. Corneocytes
B. Keratinocytes
C. Fibroblasts
D. Adipocytes

10. Skin functions:


A. Protective
B. Thermoregulation
C. Excretory
D. Sensory
E. All answers are correct
Standards of answers: 1 -C . 2 D. 3 D. 4 C. 6 E. 8
C. 10 E.
1. The symptom characteristic of scabies is:
A. Gorchakov-Ardi
B. Nikolsky
C. Jadasson
D. Kerion-Celsus
E. All answers are correct

2. Balzer's test has valuable diagnostic value at:


A. pityriasis versicolor
B. psoriasis
C. epidermophytia
D. rubromycosis
E. lichen ruber planus

3. The main elements of the skin's immune system are:


A. Langerhans cells
B. T-Lymphocytes
C. Keratinocytes
D. Merkel cells
E. Vater-Pacini corpuscle

4. The nerve endings include:


A. Merkel cells.
B. Greenstein cells.
C. Meissner corpuscle.
D. Langerhans cells.
E. Kupffer cells

5. Kebner's phenomenon:
A. elements of dermatosis are placed linearly at the sites of
excoriation
B. erosion of the oral mucosa
C. all the answers are correct

6. What is the main diagnosis of tuberculosis of the skin?


A. clinical features , course
B. the presence of tuberculosis of the internal organs
C. Mantoux test
D. data of pathohistological research
E. detection of Mycobacterium tuberculosis by PCR
F. all listed.

7. To diagnose demodicosis use:


A. microscopic analysis
B. immunofluorescent diagnosis
C. DNA diagnostics
D. microscopy in the dark field of view.

8. Which of the following is not a morphological element?


A. erythema
B. papule
C. roseola
D. urticaria
E. wetting

9. The symptom of "thimble" is characteristic of:


A. red flat herpes
B. syphilis
C. psoriasis
D. all the answers are correct

10. What is the name of the diagnostic method that allows to


determine the nature of peeling and the density of adhesion of the
scales to the skin surface?
A. dermographism
B. diascopy
C. grattage
D. isomorphic reaction
E. iodine test

Standards of answers: 1- - - - C. 5- -F. 7- -E. 9-C. 10-


C
1. The primary cavity elements of the rash include:
A. Pustula
B. Papula
C. Macula
D. Nodule
E. Erosion

2. Limited skin discoloration is called:


A. Papules
B. Pustula
C. Vesicle
D. Macula
E. Erosion

3. The primary cavity-free elements of the rash include:


A. Papules
B. Macula
C. Nodule
D. Tuberculum
E. All answers are correct

4. Clinical evaluation of the elements of skin rash involves all of the


above, except:
A. Determination of the nature of the rash (inflammatory or non-
inflammatory)
B. Prevalence of the process
C. Localization
D. Definition of morphological elements
E. Determination of skin vascular reactions

5. Lichenification is characterized by:


A. Sealing and thickening of the skin
B. Pigmentation
C. Enhanced skin pattern
D. All of the above
E. All of the above, except for pigmentation

6. The primary morphological element characteristic of shingles is:


A. Spot
B. Papule and tuberculum
C. Vesicle and bullae
D. Bullae
E. All of the above is true

7. Ointments are prescribed:


A. To insulate the skin from the effects of chemical, mechanical
injuries, friction
B. As emollients
C. As conductors of medicinal substances
D. As those that cleanse the skin of secondary layers
E. All of the above is true

8. A comprehensive clinical examination of the skin includes all of the


above, except
A. Grattage (scraping)
B. Palpation
C. Diascopy
D. Measurement of electrical resistance of the skin
E. Measurement of skin temperature

9. Specify the difference between a tuberculum and a papule:


A. Smooth surface
B. Dense consistency
C. The presence of a purulent cavity
D. Scar formation after reverse development
E. Elevation above the level of the skin

10. Inflammatory spot of large size is called:


A. Erythema
B. Hemorrhage
C. Roseola
D. Purpura
E. Leukoderma

Standards of answers1- -D, 3-E, 4-E, 5-D, 6-C. 7-E, 8-D, 9-D, 10-
1. Cavity primary elements are:
A. Urticarial element
B. Vesicle
C. Papule
D. Nodule
E. Tuberculum

2. True polymorphism is:


A. The presence of one variety of primary elements
B. The presence of various primary elements
C. The tendency of elements to merge
D. The presence of various secondary elements
E. The tendency of elements to peripheral growth

3. Ulcer is:
A. Skin defect within the epidermis
B. Skin changes in the case of massive infiltration of its papillary layer
C. The consequence of the growth of the papillary layer of the dermis
with the simultaneous thickening of the spiny layer of the epidermis
D. Defect of the skin or subcutaneous tissue

4. Hyperkeratosis is:
A. Thickening of the stratum corneum
B. Disruption of the connection between the cells of the spiny layer
C. Acute swelling of the papillae of the dermis
D. Increasing the number of cells in the granular layer
E. Thickening of the spiny layer

5. Vacuol dystrophy is:


A. Disruption of the connection between desmosomes
B. Infiltrate in the superficial parts of the dermis
C. Skin defect within the dermis
D. Accumulation of fluid in the cells of the basal and prickly layers
E. Thickening of the spiny layer

6. In place of the vesicle, the tire of which collapsed, is formed:


A. Scar
B. Ulcer
C. Excoriation
D. Erosion
E. Excoriation

7. Name the morphological basis of the tubercle:


A. Acanthosis
B. Perivascular infiltration
C. Vacuol dystrophy
D. Infectious granuloma
E. Papillomatosis

8. The patient was consulted by a patient with complaints of bright


pink, swollen elements, intense itching. 2-3 hours after the
appearance of the elements regress without a trace. Name them:
A. Tubercle
B. Nodule
C. Urticarial element
D. Bullae
E. Vesicle

9. Name the clinical differences between tubercle and papule:


A. Flat shape
B. Dimensions with lentils
C. Ulceration with scarring
D. Soft texture
E. Bluish color

10. Specify the mechanism of formation of intra-epidermal blister:


A. Acantholysis
B. Ballooning dystrophy
C. Vacuol dystrophy
D. Spongiosis
E. Exocytosis

Standards of answers: 1-B, 2-B, 3-D, 4- -D, 6-D, 7-D, 8-C, 9-C, 10-
1. Which of these nosologies are dermatozoonoses?
A. Sycosis
B. Scabies
C. Genital warts
D. Molluscum contagiosum
E. Favus.

2. There are the following clinical forms of scabies:


A. Typical
B. Nervous
C. Professional
D. Seborrheic
E. Allergic

3. What elements are considered objective signs of scabies?


A. Tuberculum
B. Nodule
C. Scabetic burrow
D. Papule
E. Crust

4. What causes scabies?


A. Pityrosporum orbiculare
B. Pediculi pubis
C. Microsporum canis
D. Sarcoptes hominis
E. Corynobacteria minutissimum

5. What is the life expectancy of a female scabies mite?


A. 1 day
B. 1 week
C. 8 weeks
D. Six months
E. 1 year

6. What topical treatment are used to treat scabies?


A. Antibacterial ointments
B. Antifungal ointments
C. Antiparasitic ointments
D. Corticosteroid ointments
E. Keratoplastic ointments

7. Which of the following pathogens is the main etiological factor in


furunculosis?
A. Pediculus pubis
B. Sarcoptes hominis
C. Staphylococcus
D. Streptococcus
E. Corynobacteria minutissimum

8. Which of the following pathogens is the main etiological factor in


hydradenitis?
A. Pediculus pubis
B. Sarcoptes hominis
C. Staphylococcus
D. Streptococcus
E. Corynobacteria minutissimum

9. For streptococcal impetigo is characterized by all of the above,


except:
A. Appearances of phlycten on the skin
B. Yellow crusts
C. Rapid spread
D. Inflammatory nodes
E. Inflammatory rim around the phlycten

10. Purulent inflammation of the apocrine glands is observed in:


A. Furunculosis;
B. Sycosis vulgaris
C. Ecthyma vulgaris
D. Hydradenitis
E. Finger's pseudofurunculosis

Standards of answers: 1 - B. 2 D. 4 D. 5 C. 6 C. 7 C. 8
C. 9 D. 10 D.
1. The most typical terms of the incubation period of scabies:
A. 2-5 days
B. 7-10 days
C. 40-50 days
D. More than two months
E. Half a year

2. The rate of scabies generalization depends on all these factors,


except:
A. The number of mites that got on the skin at the time of infection
B. Sexual and age characteristics of the skin
C. Level of itchiness
D. Hygienic skills
E. The state of immunity

3. Scabies is characterized by:


A. Lenticular papules
B. Hemorrhage
C. Dotted itchy vesicles and papules
D. Urticaria
E. Polygonal papules

4. Indicate the location of typical localization of scabies in adults?


A. The scalp
B. Face and neck
C. Spina
D. Palms and soles
E. Interdigital folds of the hands

5. What is the most common complication of scabies?


A. Secondary pyoderma
B. Sepsis
C. Cicatricial atrophy of the skin
D. Phlegmon
E. All of the above

6. In what forms of pyoderma phlycten is the main element of the


rash?
A. Vulgar sycosis
B. Hydradenitis
C. Furunculosis
D. Vulgar impetigo
E. Osteofolliculitis

7. Which of the following applies to superficial streptoderma?


A. Vulgar sycosis
B. Furuncle
C. Hydradenitis
D. Carbuncle
E. None of the above

8. The patient complains of general malaise, headache, painful


swelling on the back of the neck, which is a dense, painful cone-
shaped node, in the center - a necrotic rod. The skin around him is
swollen, infiltrated, red, hot to the touch. Your diagnosis.
A. Furuncle
B. Gummous syphilis
C. Colliquative tuberculosis
D. Hydradenitis
E. Carbuncle

9. In case of furunculosis obligatory examination includes:


A. Blood sugar level
B. Blood for bilirubin
C. Urine for creatinine
D. Feces for helminths
E. All of the above

10. The patient, 25 years old, complains of rashes in the interdigital


folds, in the area of the wrists, genitals, abdomen, which are
accompanied by severe itching, especially at night. Objectively: on the
background of unaffected skin, multiple rashes are represented by
papular and papulovesicular rashes in pairs, and excoriations. The
back is free from rashes. Your diagnosis:
A. Scabies
B. Herpes
C. Eczema
D. Neurodermatitis
E. Epidermophytia

Standards of answers: 1-B. 2-B. 3-C. 4-E. 5- -D. 7-E. 8- 9- -


1. The main parameters for the differential diagnosis of psoriasis are:
A. The primary morphological element of the rash
B. Form of rash
. The color of the rash
D. The nature and location of peeling
E. Subjective feelings
F. All answers are correct

2. Name the main pathohistological changes in psoriasis:


A. Granulosis;
B. Hyperkeratosis, parakeratosis, acanthosis
C. Parakeratosis, acanthosis
D. Acanthosis
E. Polymorphic-cellular infiltration.

3. Clinical forms of psoriasis include:


A. Limited psoriasis
B. Psoriatic arthropathy
C. Sclero-atrophic psoriasis
D. Common psoriasis

4. Seasonal forms of psoriasis are:


A. Winter
B. Mixed
C. Early
D. Congenital
E. Autumn

5. List the clinical variants of lichen ruber planus:


A. Annular form
B. Erosive-ulcerative
C. Hypertrophic form
D. Bullous form
E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:


A. The presence of new papular rashes
B. The presence of a tendency to peripheral growth
C. Auspitz's positive psoriatic triad
D. Positive symptom of Koebner
E. Erythroderma

7. With what diseases it is necessary to carry out differential


diagnosis at suspicion of existence at the patient of a lichen ruber
planus?
A. Psoriasis
B. Dermatomycosis
C. Diffuse neurodermatitis
D. Toxicoderma
E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?


A. The form of papules is miliary
B. Inflammatory papules
C. Non-inflammatory papules
D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:


A. No itching
B. Itchy skin only at night
C. The appearance of rashes only on the extensor surfaces of the
extremities
D. Wickham's symptom
E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:
A. UVI (ultraviolet irradiation)
B. Balneotherapy
C. PUVA - therapy
D. UHF therapy (ultra-high frequency)
E. All answers are correct
Standards of answers: 1 - F. 2 B. 3 B. 4 F. 6 C. 7
B. 9 D. 10 E.
1. Choose the diagnostic phenomena characteristic of psoriasis:
A. The Kebner phenomenon
B. Symptom of stearin stain
C. Symptom of the terminal film
D. Symptom of Auschpitz
E. All answers are correct

2. Choose a symptom pathognomonic for LRP:


A. Nikolsky's symptom
B. Benier-Meshchersky's symptom
C. Wickham's symptom
D. Symptom Gorchakov-Ardi
E. Yadasson's symptom

3. For the local treatment of psoriasis use:


A. Lorinden ointment - A
B. 2% salicylic ointment
C. 3% naphthalene ointment
D. Dermovate
E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:


A. The elements are completely covered with silvery-white scales
B. On the periphery of the papules - hyperemic border (Pilnov )
C. The appearance of new rashes
D. Peripheral growth of elements
E. Pale pink color of rash elements

5. For the regressive stage of psoriasis is characterized by:


A. Around the elements - "pseudoatrophic" Voronov
B. Disappearance of rashes
C. Pale color of the rash elements
D. Disappearance of scales from the surface of psoriatic rashes
E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?
A. flexion surface of the extremities
B. extensor surface of the extremities
C. interdigital spaces
D. skin around physiological openings
E. genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?


A. psoriatic triad
B. the Kebner phenomenon
C. Symptom of Auspices
D. the phenomenon of "blood dew"
E. the phenomenon of "apple jelly"

8. What clinical sign is not characteristic of the progressive stage of


psoriasis?
A. tendency to merge
B. the presence of a psoriatic triad
C. silvery-white peeling in the center of the papule
D. the Kebner phenomenon
E. silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?


A. yellow-red color
B. umbilical indentation in the center of the papule
C. oval shape
D. the surface is covered with white scales
E. shiny surface

10. Clinical varieties of psoriasis do not include:


A. seborrheic
B. leaf-like
C. exudative
D. vulgar
E. rupee

Standards of answers: 1-E. 2-C. 3-E. 4- 5-E. 6-B. 7-E. 8-E. 9-D. 10-B
1. The main parameters for the differential diagnosis of psoriasis are:
A. The primary morphological element of the rash
B. Form of rash
. The color of the rash
D. The nature and location of peeling
E. Subjective feelings
F. All answers are correct

2. Name the main pathohistological changes in psoriasis:


A. Granulosis;
B. Hyperkeratosis, parakeratosis, acanthosis
C. Parakeratosis, acanthosis
D. Acanthosis
E. Polymorphic-cellular infiltration.

3. Clinical forms of psoriasis include:


A. Limited psoriasis
B. Psoriatic arthropathy
C. Sclero-atrophic psoriasis
D. Common psoriasis

4. Seasonal forms of psoriasis are:


A. Winter
B. Mixed
C. Early
D. Congenital
E. Autumn

5. List the clinical variants of lichen ruber planus:


A. Annular form
B. Erosive-ulcerative
C. Hypertrophic form
D. Bullous form
E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:


A. The presence of new papular rashes
B. The presence of a tendency to peripheral growth
C. Auspitz's positive psoriatic triad
D. Positive symptom of Koebner
E. Erythroderma

7. With what diseases it is necessary to carry out differential


diagnosis at suspicion of existence at the patient of a lichen ruber
planus?
A. Psoriasis
B. Dermatomycosis
C. Diffuse neurodermatitis
D. Toxicoderma
E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?


A. The form of papules is miliary
B. Inflammatory papules
C. Non-inflammatory papules
D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:


A. No itching
B. Itchy skin only at night
C. The appearance of rashes only on the extensor surfaces of the
extremities
D. Wickham's symptom
E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:
A. UVI (ultraviolet irradiation)
B. Balneotherapy
C. PUVA - therapy
D. UHF therapy (ultra-high frequency)
E. All answers are correct
Standards of answers: 1 - F. 2 B. 3 B. 4 F. 6 C. 7
B. 9 D. 10 E.
1. Choose the diagnostic phenomena characteristic of psoriasis:
A. The Kebner phenomenon
B. Symptom of stearin stain
C. Symptom of the terminal film
D. Symptom of Auschpitz
E. All answers are correct

2. Choose a symptom pathognomonic for LRP:


A. Nikolsky's symptom
B. Benier-Meshchersky's symptom
C. Wickham's symptom
D. Symptom Gorchakov-Ardi
E. Yadasson's symptom

3. For the local treatment of psoriasis use:


A. Lorinden ointment - A
B. 2% salicylic ointment
C. 3% naphthalene ointment
D. Dermovate
E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:


A. The elements are completely covered with silvery-white scales
B. On the periphery of the papules - hyperemic border (Pilnov )
C. The appearance of new rashes
D. Peripheral growth of elements
E. Pale pink color of rash elements

5. For the regressive stage of psoriasis is characterized by:


A. Around the elements - "pseudoatrophic" Voronov
B. Disappearance of rashes
C. Pale color of the rash elements
D. Disappearance of scales from the surface of psoriatic rashes
E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?
A. flexion surface of the extremities
B. extensor surface of the extremities
C. interdigital spaces
D. skin around physiological openings
E. genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?


A. psoriatic triad
B. the Kebner phenomenon
C. Symptom of Auspices
D. the phenomenon of "blood dew"
E. the phenomenon of "apple jelly"

8. What clinical sign is not characteristic of the progressive stage of


psoriasis?
A. tendency to merge
B. the presence of a psoriatic triad
C. silvery-white peeling in the center of the papule
D. the Kebner phenomenon
E. silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?


A. yellow-red color
B. umbilical indentation in the center of the papule
C. oval shape
D. the surface is covered with white scales
E. shiny surface

10. Clinical varieties of psoriasis do not include:


A. seborrheic
B. leaf-like
C. exudative
D. vulgar
E. rupee

Standards of answers: 1-E. 2-C. 3-E. 4- -E. 6-B. 7-E. 8-E. 9-D. 10-B
1. For which disease is the pathognomonic iodine test of Balzer?
A. Microsporia
B. Inguinal epidermophytia
C. Pytiriasis versicolor
D. Candidiasis
E. Rubrophytia

2. What methods are used to diagnose Pytiriasis versicolor?


A. Microscopic examination
B. Luminescent method using a Wood lamp
C. Balzer test with iodine tincture
D. Benier's symptom method (chip phenomenon)
E. All answers are correct

3. What elements of the rash are characteristic of Pytiriasis


versicolor?
A. Papule
B. Macule
C. Nodule
D. Vesicle
E. Pustule

4. What pathogen Pytiriasis versicolor?


A. Trich. mentagrophytes
B. Microsporum canis
C. Pityrosporum orbiculare
D. Pityrosporum ovale
E. Candida albicans
F. Trich. rubrum

5. Concomitant diseases that are most common in children with


candidiasis are:
A. Chronic recurrent acute respiratory viral infections, bronchitis,
pneumonia
B. Purulent otitis and chronic tonsillitis
C. Atopic dermatitis
D. Asthmoid bronchitis
E. Everything is listed

6. What pathogen causes infiltrative-suppurative trichophytia


(kerion)?
A. Trich. violaceum
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

7. What pathogen causes anthropophilic microsporia?


A. Trich. mentagrophytes
B. Microsporum ferrugineum
C. Pityrosporum orbiculare
D. Candida albicans
E. Trich. rubrum

8. Indicate the most important clinical sign of microsporia of the


scalp.
A. Scales
B. Hyperemia
C. Focal nature of the lesion
D. Broken hairs
E. Crusts

9. In the treatment of microsporia of the scalp griseofulvin prescribed


in a dose of:
A. 22 mg per day
B. 22 mg three times a day
C. 22 mg per kg of body weight three times a day
D. 22 mg per kg of body weight per day
E. 2 mg per reception

10. What pathogen causes epidermophytia of the feet?


A. Trich. mentagrophytes var. interdigital
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

Standards of answers: 1 - C. 2 E. 3 B. 4 C. 5 E. 6 D. 7 B. 8
D. 9 D. 10
1. With what diseases most often have to differentiate the microspores
of the scalp?
A. Pityriasis versicolor
B. Lichen ruber planus
C. Pityriasis rosea
D. Alopecia areata

2. What are the clinical symptoms characteristic of infiltrative-


suppurative trichophytia of the scalp?
A. Intoxication
B. Lymphadenitis
C. Rising body temperature
D. Hair loss in the lesion
E. All answers are correct

3. What methods of laboratory diagnosis should be carried out in


trichomycoses:
A. Histological
B. Microscopic
C. Bacteriological

4. What is used for laboratory diagnosis of trichomycoses:


A. Blood
B. Nails, hair, scales
C. Cerebrospinal fluid
D. The content of the sebaceous glands

5. What clinical varieties belong to the mycosis of the feet caused by


Trich. mentagrophytes var. interdigetale
A. Intertriginous
B. Onychomycosis
C. Dyshydrotic
D. Squamous-hyperkeratotic
E. All answers are correct

6. For which disease is the pathognomonic symptom "Honeycombs"?


A. Microsporia
B. Infiltrative-suppurative trichophytia
C. Pityriasis versicolor
D. Candidiasis
E. Rubrophytia
7. What drugs are used to treat dermatophytes?
A. Griseofulvin
B. Oxolinic ointment
C. Tetracycline
D. Nystatin
E. Prednisolone

8. Specify a diagnostic test that confirms the diagnosis of microsporia


of the scalp:
A. Scraping is a symptom of "blood dew"
B. In smears - acantholytic cells.
C. Detection of mycelium in scales.
D. The appearance of blisters in the application test with 50%
potassium iodide ointment.
E. Brock's rehearsal.

9. What diagnostic test can be performed to diagnose " Pityriasis


versicolor ":
A. Diascopy.
B. The Auspices trial.
B. Balzer's test.
G. Yadason's test.
D. Thompson's test.

10. Choose a drug that is used to treat tinea pedis:


A. Flucinar.
B. Sulfur ointment 20%.
B. Mycoseptin.
G. Sinaflan.
D. Elocom.
Standards of answers: 1-D. 2-E. 3-B. 4-B. 5-E. 6-B. 7- -C. 9-C. 10-C
1. Characteristic feature of simple contact dermatitis is:
A. Fuzzy boundaries of the lesion
B. Clear boundaries of the lesion
C. Occurrence only in sensitized patients
D. Occurrence in 12-74 hour after exposure to a certain factor
E. Possible generalization of the process

2. It is not observed in allergic contact dermatitis:


A. Rash on the place of influence of a certain factor
B. Clear boundaries of the lesion
C. Occurrence in sensitized patients
D. Subacute onset and course
E. Possible recurrence after re-exposure to the allergen

3. Which of the following is not used for the treatment of allergic


contact
dermatitis:
A. Glucocorticoids containing creams and ointments
B. Antihistamines
C. Hyposensitizing drugs
D. Vitamins
E. Photosensitizers

4. Toxicodermatosis is not characterized by:


A. Acute onset
B. Symmetry of rash
C. Polymorphic rash
D. Development of lichenification
E. Possible lesion of mucous membranes

5. Fixed erythema is not characterized by:


A. Occurrence as a result of taking sulfonamides, antibiotics etc.
B. Occurrence due to exposure to obligate irritants
C. Rash of several red spots 2-5 cm in diameter
D. Localization on the skin, genital and oral mucosa
E. After recourse pigmentation remains for a long time

6. Which of the following is not applied for the treatment of


toxicodermatosis:
A. Enterosorbents
B. Photosensitizers
C. Antihistamine drug
D. Detoxification drugs
E. Glucocorticoid creams

7. Lyell's syndrome is characterized by:


A. Isomorphic Koebner response
B. Auspitz triad
C. Nikolsky's symptom
D. Meshcherskiy-Besnier's symptom
E. Jadassohn's symptom

8. Which of the following form is not characteristic for eczema:


A. Idiopathic
B. Microbial
C. Herpetiformal
D. Occupational
E. Seborrheal

9. Which of the following does not belong to the main diagnostic


criteria for
assessment of the severity of atopic dermatitis:
A. Skin itch
B. Ichthyosis, mostly of palms
C. Typical morphology and localization of skin rashes: in infants
are eczematous rash on the face and extensor surfaces of the
extremities, in older children and adults - lichenification on
flexor surfaces of thextremities
D. Chronic relapsing course
E. Atopy in personal and family history

10. Primary morphological element with urticaria is considered:


A. Vesicle
B. Bulla
C. Macule
D. Blister
E. Knot

Standards of answers: 1 B, 2 B, 3 -D, 5 B, 6 C, 8 C, 9 B, 10


D.
1. What is the recommended topical treatment in seborrheic
dermatitis like psoriasis of the face and ear canals?
A. Photochemotherapy
B. Reflexotherapy
C. Acyclovir
D. Mineral oil
E. Clobetasol propionate

2. Everything mentioned below is specific to allergic contact


dermatitis, except:
A. Sensibilization
B. Margination of lesions spreads in the periphery beyond the
actual site of exposure
C. ACD is due to reexposure to a substance to which the
individual is sensitized
D. Margins of lesions are sharp
E. Polymorphism of skin eruption

3. Histopathology in acute irritant contact dermatitis:


A. Epidermal cell necrosis, neutrophils, vesiculation, and
necrosis
B. Acanthosis, hyperkeratosis, lymphocytic infiltrate
C. Spongiosis, lymphocytes and eosinophils in the epidermis,
and monocyte and histiocyte infiltration in the dermis
D. Spongiosis plus acantosis, elongation of rete ridges, and
elongation and broadening of papillae; hyperkeratosis; and a
lymphocytic infiltrate

4. The most common form of occupational skin diseases is:


A. Irritant contact dermatitis
B. Allergic contact dermatitis
C. Atopic dermatitis
D. Nummular eczema
E. Toxidermia

5. Which are the clinical symptoms of mycotic eczema?


A. The presence of pustules
B. Vesiculation
C. Increasing of lymph nodes
D. No correct answer
6. The plumber came to the doctor complaining of redness,
burning sensation, pain in the right forearm. Some rash appeared in
10-15 minutes after contact with hot pipes. Objectively: on the skin of
the right forearm extensor surface there is a severe focus with clear
boundaries of 3x6 cm; there is skin hyperemia in the focus, some
individual bullous elements with clear content. Make a diagnosis:
A. Dermatitis herpetiformis Duhring
B. Allergic contact dermatitis
C. Eczema
D. Simple contact dermatitis
E. Pemphigus vulgaris

7. 32-years old female patient consulted the dermatologist


complaining of some rash on the skin of neck and chest, accompanied
by itching. Rash appeared after taking aspirin and kept on the skin for
about two hours and then without any action gradually disappeared
appearing at new areas. Objectively, there are multiple palm-sized
urticaria elements. The patient has red dermographism; eosinophilia
is revealed in the blood. What kind of skin disease can be thought of in
this case:
A. Urticaria
B. Allergic dermatitis
C. Eczema
D. Simple contact dermatitis
E. Atopic dermatitis

8. A boy of 7 years complains of feeling unwell, pain on swallowing,


painful rashes on the lips and in the mouth, itchy rash on the face and
body, which appeared three days after receiving Analgin because of
acute otitis. Objectively: the general state of the child is severe; body
temperature is 38.6 °C. On the skin of the lips and oral mucosa, there
are common erosions with massive hemorrhagic crusts. On the face
and body multiple erythematous spots and edematous papules with
deep bluish center, on the surface of which there are vesicles and
blisters; the elements tend to be drained. Nickolsky's sign is negative.
What kind of emergency prehospital care should be provided to the
child:
A. To prescribe corticosteroids orally, canceling all other drugs
B. To prescribe corticosteroids parenterally, canceling all other
drugs
C. To prescribe corticosteroid ointments, canceling all other
drugs
D. To prescribe antihistamine drugs, canceling all other drugs
E. To prescribe purgatives, canceling all other drugs

9. Female patient, 37 years old, employed as a manipulative nurse,


complains of feeling unwell, weakness, headache, muscle and joint
pain and skin rash, accompanied by severe pain and burning
sensation. Some rash appeared two days after receiving ampicillin
because of sore throat. Objectively: general condition of the patient is
severe; body temperature is 39.2 °C. The entire skin is bloodshot. On
the trunk and extremities, there are multiple bullous elements,
erosion, fragments of epidermis observed. The skin is painful on
palpation. Nikolsky's sign is positive. What kind of emergency pre-
hospital care should not be provided to the child:
A. Stop taking ampicillin
B. To prescribe corticosteroids parenterally
C. To prescribe enterosorbents
D. To refer the patient to the intensive care unit for further
treatment
E. To refer the patient for consultation and supervision of the
allergist

10. 34 years old woman consulted the dermatologist about


the skin lesions of hands and lower third of the forearm as a
significant swelling, redness, vesiculation. Got ill one week ago.
The disease appeared after use of 'Lotus' washing powder. In the
past, the patient has no skin diseases. What is the most likely
diagnosis in this patient:
A. Contact allergic dermatitis
B. Simple contact dermatitis
C. Dyshidrotic eczema
D. Toxicodermatosis
E. Microbial eczema

Standards of answers: 1 E, 2 D, 3 B, 4 B, 5 B, 6 D, 7 A, 8
B, 9 A, 10 A
1. What are the main pathohistological changes in pemphigus
vulgaris?
A. Spongiosis
B. Acanthosis
C. Acantholysis
D. Hyperkeratosis
E. Parakeratosis

2. The most important laboratory tests to confirm the diagnosis of


pemphigus vulgaris are:
A. Sowing the contents of the blister on the flora
B. Clinical blood test
C. Blood tests for electrolytes
D. Investigation of smears-imprints on acantholytic cells
E. Investigation of blister contents for eosinophils

3. Indicate the most important diagnostic symptom to confirm the


diagnosis of pemphigus:
A. The Kebner phenomenon
B. Nikolsky's symptom
C. Balzer's test
D. Mantoux reaction
E. Isomorphic reaction

4. The most characteristic morphological elements for Duhring's


herpetiform dermatosis are:
A. Erythematous macules
B. Papules
C. Bullae
D. Vesicles
E. All of the above is true

5. In which layer of the skin are the blisters in the case of pemphigus
vulgaris?
A. Papillary
B. Basal
C. Spinosum
D. Granular
E. Corneum

6. Acantholytic cells by the method of Tzank detected by the study:


A. Histological
B. Bacteriological
C. Cytological
D. Fluorescent
E. Serological

7. Acantholysis is:
A. Melting of intercellular connections in the spinous layer
B. Degenerative changes in the spinous layer
C. Thickening of the stratum corneum
D. Growth of the granular layer
E. Violation of the process of keratinization and preservation of
nuclei in the cells of the stratum corneum

8. Specify the primary morphological element typical of pemphigus


vulgaris:
A. Bullae
B. Microvesicle
C. Papule
D. Urtica
E. Pustula.

9. Bullae in the case of true vesicles are placed:


A. Subcorneally
B. Intraepidermal
C. Subepidermal
D. Subdermally
E. Subhypodermal

10. In the study of Tzank material is stained by the method:


A. Gram
B. Tiel-Nielsen
C. Romanovsky-Gimse
D. Burry
E. Morozov

Standards of answers:: 1 - C. 2 D. 3 B. 4 E. 5 C. 6 C. 7
B. 10 C
1. Acantholytic cells by the method of Tzank found in:
A. Native culture
B. Histological preparation
C. Smear-imprint
D. Blood tests
E. Serological examination.

2. In the case of localization of rashes with pemphigus vulgaris on the


oral mucosa, histopathological changes (acantholysis) occur in:
A. The granular layer
B. Spiny layer
C. Basal layer
D. Actually the mucous plate
E. Submucosal layer

3. The most typical localization of rashes in pemphigus vulgaris:


A. The scalp
B. Face
C. The mucous membrane of the oral cavity
D. Elbows and knees
E. Palms and soles

4. To confirm the diagnosis of Duhring's herpetiform dermatitis it is


necessary to conduct a skin test to determine hypersensitivity to:
A. Sulfanilamides
B. Antibiotics
C. Novocaine
D. Iodides
E. Bromide
5. What are the characteristics of Duhring's herpetiform dermatitis?
A. Recurrent course
B. Monomorphism of rashes
C. No itching
D. Positive symptom of Nikolsky
E. Frequent lesions of the mucous membranes

6. Bullae in the case of Duhring's dermatitis are placed:


A. Subcorneally
B. Intraepidermal
C. Subepidermal
D. Subdermally
E. Subhypodermal

7. At what bullous dermatosis at patients hypersensitivity to gluten is


quite often observed?
A. Pemphigus vulgaris
B. Exfoliative pemphigus
C. Duhring's dermatitis
D. Stevens-Johnson syndrome
E. Seborrheic pemphigus

8. With Duhring's dermatosis, patients complain of:


A. Pain
B. Itching
C. Feeling of cold extremities
D. The feeling of crawling "ants" on the body
E. Paresthesia

9. Specify the most effective drug for the treatment of pemphigus:


A. Penicillin
B. Sulfadimethoxine
C. Ftivazid
D. Prednisolone
E. Delagil

10. For the treatment of Duhring's herpetiform dermatitis most often


used:
A. Antibiotics
B. Vitamins
C. Antihistamines
D. Preparations of the sulfone series (DDS)
E. Antimalarial drugs

Standards of answers: 1-C. 2-B. 3-C. 4-D. 5- -C. 7-C. 8-B. 9-D. 10-D
1. For which disease is the pathognomonic iodine test of Balzer?
A. Microsporia
B. Inguinal epidermophytia
C. Pytiriasis versicolor
D. Candidiasis
E. Rubrophytia

2. What methods are used to diagnose Pytiriasis versicolor?


A. Microscopic examination
B. Luminescent method using a Wood lamp
C. Balzer test with iodine tincture
D. Benier's symptom method (chip phenomenon)
E. All answers are correct

3. What elements of the rash are characteristic of Pytiriasis


versicolor?
A. Papule
B. Macule
C. Nodule
D. Vesicle
E. Pustule

4. What pathogen Pytiriasis versicolor?


A. Trich. mentagrophytes
B. Microsporum canis
C. Pityrosporum orbiculare
D. Pityrosporum ovale
E. Candida albicans
F. Trich. rubrum

5. Concomitant diseases that are most common in children with


candidiasis are:
A. Chronic recurrent acute respiratory viral infections, bronchitis,
pneumonia
B. Purulent otitis and chronic tonsillitis
C. Atopic dermatitis
D. Asthmoid bronchitis
E. Everything is listed

6. What pathogen causes infiltrative-suppurative trichophytia


(kerion)?
A. Trich. violaceum
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

7. What pathogen causes anthropophilic microsporia?


A. Trich. mentagrophytes
B. Microsporum ferrugineum
C. Pityrosporum orbiculare
D. Candida albicans
E. Trich. rubrum

8. Indicate the most important clinical sign of microsporia of the


scalp.
A. Scales
B. Hyperemia
C. Focal nature of the lesion
D. Broken hairs
E. Crusts

9. In the treatment of microsporia of the scalp griseofulvin prescribed


in a dose of:
A. 22 mg per day
B. 22 mg three times a day
C. 22 mg per kg of body weight three times a day
D. 22 mg per kg of body weight per day
E. 2 mg per reception

10. What pathogen causes epidermophytia of the feet?


A. Trich. mentagrophytes var. interdigital
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

Standards of answers: 1 - C. 2 E. 3 B. 4 C. 5 E. 6 D. 7 B. 8
D. 9 D. 10
1. With what diseases most often have to differentiate the microspores
of the scalp?
A. Pityriasis versicolor
B. Lichen ruber planus
C. Pityriasis rosea
D. Alopecia areata

2. What are the clinical symptoms characteristic of infiltrative-


suppurative trichophytia of the scalp?
A. Intoxication
B. Lymphadenitis
C. Rising body temperature
D. Hair loss in the lesion
E. All answers are correct

3. What methods of laboratory diagnosis should be carried out in


trichomycoses:
A. Histological
B. Microscopic
C. Bacteriological

4. What is used for laboratory diagnosis of trichomycoses:


A. Blood
B. Nails, hair, scales
C. Cerebrospinal fluid
D. The content of the sebaceous glands

5. What clinical varieties belong to the mycosis of the feet caused by


Trich. mentagrophytes var. interdigetale
A. Intertriginous
B. Onychomycosis
C. Dyshydrotic
D. Squamous-hyperkeratotic
E. All answers are correct

6. For which disease is the pathognomonic symptom "Honeycombs"?


A. Microsporia
B. Infiltrative-suppurative trichophytia
C. Pityriasis versicolor
D. Candidiasis
E. Rubrophytia
7. What drugs are used to treat dermatophytes?
A. Griseofulvin
B. Oxolinic ointment
C. Tetracycline
D. Nystatin
E. Prednisolone

8. Specify a diagnostic test that confirms the diagnosis of microsporia


of the scalp:
A. Scraping is a symptom of "blood dew"
B. In smears - acantholytic cells.
C. Detection of mycelium in scales.
D. The appearance of blisters in the application test with 50%
potassium iodide ointment.
E. Brock's rehearsal.

9. What diagnostic test can be performed to diagnose " Pityriasis


versicolor ":
A. Diascopy.
B. The Auspices trial.
B. Balzer's test.
G. Yadason's test.
D. Thompson's test.

10. Choose a drug that is used to treat tinea pedis:


A. Flucinar.
B. Sulfur ointment 20%.
B. Mycoseptin.
G. Sinaflan.
D. Elocom.

Standards of answers: 1-D. 2-E. 3-B. 4-B. 5-E. 6-B. 7- -C. 9-C. 10-C
1. Characteristic feature of simple contact dermatitis is:
A. Fuzzy boundaries of the lesion
B. Clear boundaries of the lesion
C. Occurrence only in sensitized patients
D. Occurrence in 12-74 hour after exposure to a certain factor
E. Possible generalization of the process

2. It is not observed in allergic contact dermatitis:


A. Rash on the place of influence of a certain factor
B. Clear boundaries of the lesion
C. Occurrence in sensitized patients
D. Subacute onset and course
E. Possible recurrence after re-exposure to the allergen

3. Which of the following is not used for the treatment of allergic


contact
dermatitis:
A. Glucocorticoids containing creams and ointments
B. Antihistamines
C. Hyposensitizing drugs
D. Vitamins
E. Photosensitizers

4. Toxicodermatosis is not characterized by:


A. Acute onset
B. Symmetry of rash
C. Polymorphic rash
D. Development of lichenification
E. Possible lesion of mucous membranes

5. Fixed erythema is not characterized by:


A. Occurrence as a result of taking sulfonamides, antibiotics etc.
B. Occurrence due to exposure to obligate irritants
C. Rash of several red spots 2-5 cm in diameter
D. Localization on the skin, genital and oral mucosa
E. After recourse pigmentation remains for a long time

6. Which of the following is not applied for the treatment of


toxicodermatosis:
A. Enterosorbents
B. Photosensitizers
C. Antihistamine drug
D. Detoxification drugs
E. Glucocorticoid creams

7. Lyell's syndrome is characterized by:


A. Isomorphic Koebner response
B. Auspitz triad
C. Nikolsky's symptom
D. Meshcherskiy-Besnier's symptom
E. Jadassohn's symptom

8. Which of the following form is not characteristic for eczema:


A. Idiopathic
B. Microbial
C. Herpetiformal
D. Occupational
E. Seborrheal

9. Which of the following does not belong to the main diagnostic


criteria for
assessment of the severity of atopic dermatitis:
A. Skin itch
B. Ichthyosis, mostly of palms
C. Typical morphology and localization of skin rashes: in infants
are eczematous rash on the face and extensor surfaces of the
extremities, in older children and adults - lichenification on
flexor surfaces of thextremities
D. Chronic relapsing course
E. Atopy in personal and family history

10. Primary morphological element with urticaria is considered:


A. Vesicle
B. Bulla
C. Macule
D. Blister
E. Knot

Standards of answers: 1 B, 2 B, 3 -D, 5 B, 6 C, 8 C, 9 B, 10


D.
1. What is the recommended topical treatment in seborrheic
dermatitis like psoriasis of the face and ear canals?
A. Photochemotherapy
B. Reflexotherapy
C. Acyclovir
D. Mineral oil
E. Clobetasol propionate

2. Everything mentioned below is specific to allergic contact


dermatitis, except:
A. Sensibilization
B. Margination of lesions spreads in the periphery beyond the
actual site of exposure
C. ACD is due to reexposure to a substance to which the
individual is sensitized
D. Margins of lesions are sharp
E. Polymorphism of skin eruption

3. Histopathology in acute irritant contact dermatitis:


A. Epidermal cell necrosis, neutrophils, vesiculation, and
necrosis
B. Acanthosis, hyperkeratosis, lymphocytic infiltrate
C. Spongiosis, lymphocytes and eosinophils in the epidermis,
and monocyte and histiocyte infiltration in the dermis
D. Spongiosis plus acantosis, elongation of rete ridges, and
elongation and broadening of papillae; hyperkeratosis; and a
lymphocytic infiltrate

4. The most common form of occupational skin diseases is:


A. Irritant contact dermatitis
B. Allergic contact dermatitis
C. Atopic dermatitis
D. Nummular eczema
E. Toxidermia

5. Which are the clinical symptoms of mycotic eczema?


A. The presence of pustules
B. Vesiculation
C. Increasing of lymph nodes
D. No correct answer
6. The plumber came to the doctor complaining of redness,
burning sensation, pain in the right forearm. Some rash appeared in
10-15 minutes after contact with hot pipes. Objectively: on the skin of
the right forearm extensor surface there is a severe focus with clear
boundaries of 3x6 cm; there is skin hyperemia in the focus, some
individual bullous elements with clear content. Make a diagnosis:
A. Dermatitis herpetiformis Duhring
B. Allergic contact dermatitis
C. Eczema
D. Simple contact dermatitis
E. Pemphigus vulgaris

7. 32-years old female patient consulted the dermatologist


complaining of some rash on the skin of neck and chest, accompanied
by itching. Rash appeared after taking aspirin and kept on the skin for
about two hours and then without any action gradually disappeared
appearing at new areas. Objectively, there are multiple palm-sized
urticaria elements. The patient has red dermographism; eosinophilia
is revealed in the blood. What kind of skin disease can be thought of in
this case:
A. Urticaria
B. Allergic dermatitis
C. Eczema
D. Simple contact dermatitis
E. Atopic dermatitis

8. A boy of 7 years complains of feeling unwell, pain on swallowing,


painful rashes on the lips and in the mouth, itchy rash on the face and
body, which appeared three days after receiving Analgin because of
acute otitis. Objectively: the general state of the child is severe; body
temperature is 38.6 °C. On the skin of the lips and oral mucosa, there
are common erosions with massive hemorrhagic crusts. On the face
and body multiple erythematous spots and edematous papules with
deep bluish center, on the surface of which there are vesicles and
blisters; the elements tend to be drained. Nickolsky's sign is negative.
What kind of emergency prehospital care should be provided to the
child:
A. To prescribe corticosteroids orally, canceling all other drugs
B. To prescribe corticosteroids parenterally, canceling all other
drugs
C. To prescribe corticosteroid ointments, canceling all other
drugs
D. To prescribe antihistamine drugs, canceling all other drugs
E. To prescribe purgatives, canceling all other drugs

9. Female patient, 37 years old, employed as a manipulative nurse,


complains of feeling unwell, weakness, headache, muscle and joint
pain and skin rash, accompanied by severe pain and burning
sensation. Some rash appeared two days after receiving ampicillin
because of sore throat. Objectively: general condition of the patient is
severe; body temperature is 39.2 °C. The entire skin is bloodshot. On
the trunk and extremities, there are multiple bullous elements,
erosion, fragments of epidermis observed. The skin is painful on
palpation. Nikolsky's sign is positive. What kind of emergency pre-
hospital care should not be provided to the child:
A. Stop taking ampicillin
B. To prescribe corticosteroids parenterally
C. To prescribe enterosorbents
D. To refer the patient to the intensive care unit for further
treatment
E. To refer the patient for consultation and supervision of the
allergist

10. 34 years old woman consulted the dermatologist about


the skin lesions of hands and lower third of the forearm as a
significant swelling, redness, vesiculation. Got ill one week ago.
The disease appeared after use of 'Lotus' washing powder. In the
past, the patient has no skin diseases. What is the most likely
diagnosis in this patient:
A. Contact allergic dermatitis
B. Simple contact dermatitis
C. Dyshidrotic eczema
D. Toxicodermatosis
E. Microbial eczema

Standards of answers: 1 E, 2 D, 3 B, 4 B, 5 B, 6 D, 7 A, 8
B, 9 A, 10 A.
1. The main parameters for the differential diagnosis of psoriasis are:
A. The primary morphological element of the rash
B. Form of rash
. The color of the rash
D. The nature and location of peeling
E. Subjective feelings
F. All answers are correct

2. Name the main pathohistological changes in psoriasis:


A. Granulosis;
B. Hyperkeratosis, parakeratosis, acanthosis
C. Parakeratosis, acanthosis
D. Acanthosis
E. Polymorphic-cellular infiltration.

3. Clinical forms of psoriasis include:


A. Limited psoriasis
B. Psoriatic arthropathy
C. Sclero-atrophic psoriasis
D. Common psoriasis

4. Seasonal forms of psoriasis are:


A. Winter
B. Mixed
C. Early
D. Congenital
E. Autumn

5. List the clinical variants of lichen ruber planus:


A. Annular form
B. Erosive-ulcerative
C. Hypertrophic form
D. Bullous form
E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:


A. The presence of new papular rashes
B. The presence of a tendency to peripheral growth
C. Auspitz's positive psoriatic triad
D. Positive symptom of Koebner
E. Erythroderma

7. With what diseases it is necessary to carry out differential


diagnosis at suspicion of existence at the patient of a lichen ruber
planus?
A. Psoriasis
B. Dermatomycosis
C. Diffuse neurodermatitis
D. Toxicoderma
E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?


A. The form of papules is miliary
B. Inflammatory papules
C. Non-inflammatory papules
D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:


A. No itching
B. Itchy skin only at night
C. The appearance of rashes only on the extensor surfaces of the
extremities
D. Wickham's symptom
E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:
A. UVI (ultraviolet irradiation)
B. Balneotherapy
C. PUVA - therapy
D. UHF therapy (ultra-high frequency)
E. All answers are correct
Standards of answers: 1 - F. 2 B. 3 B. 4 F. 6 C. 7
B. 9 D. 10 E.
1. Choose the diagnostic phenomena characteristic of psoriasis:
A. The Kebner phenomenon
B. Symptom of stearin stain
C. Symptom of the terminal film
D. Symptom of Auschpitz
E. All answers are correct

2. Choose a symptom pathognomonic for LRP:


A. Nikolsky's symptom
B. Benier-Meshchersky's symptom
C. Wickham's symptom
D. Symptom Gorchakov-Ardi
E. Yadasson's symptom

3. For the local treatment of psoriasis use:


A. Lorinden ointment - A
B. 2% salicylic ointment
C. 3% naphthalene ointment
D. Dermovate
E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:


A. The elements are completely covered with silvery-white scales
B. On the periphery of the papules - hyperemic border (Pilnov )
C. The appearance of new rashes
D. Peripheral growth of elements
E. Pale pink color of rash elements

5. For the regressive stage of psoriasis is characterized by:


A. Around the elements - "pseudoatrophic" Voronov
B. Disappearance of rashes
C. Pale color of the rash elements
D. Disappearance of scales from the surface of psoriatic rashes
E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?
A. flexion surface of the extremities
B. extensor surface of the extremities
C. interdigital spaces
D. skin around physiological openings
E. genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?


A. psoriatic triad
B. the Kebner phenomenon
C. Symptom of Auspices
D. the phenomenon of "blood dew"
E. the phenomenon of "apple jelly"

8. What clinical sign is not characteristic of the progressive stage of


psoriasis?
A. tendency to merge
B. the presence of a psoriatic triad
C. silvery-white peeling in the center of the papule
D. the Kebner phenomenon
E. silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?


A. yellow-red color
B. umbilical indentation in the center of the papule
C. oval shape
D. the surface is covered with white scales
E. shiny surface

10. Clinical varieties of psoriasis do not include:


A. seborrheic
B. leaf-like
C. exudative
D. vulgar
E. rupee

Standards of answers: 1-E. 2-C. 3-E. 4- -E. 6-B. 7-E. 8-E. 9-D. 10-B
1. What are the main pathohistological changes in pemphigus
vulgaris?
A. Spongiosis
B. Acanthosis
C. Acantholysis
D. Hyperkeratosis
E. Parakeratosis

2. The most important laboratory tests to confirm the diagnosis of


pemphigus vulgaris are:
A. Sowing the contents of the blister on the flora
B. Clinical blood test
C. Blood tests for electrolytes
D. Investigation of smears-imprints on acantholytic cells
E. Investigation of blister contents for eosinophils

3. Indicate the most important diagnostic symptom to confirm the


diagnosis of pemphigus:
A. The Kebner phenomenon
B. Nikolsky's symptom
C. Balzer's test
D. Mantoux reaction
E. Isomorphic reaction

4. The most characteristic morphological elements for Duhring's


herpetiform dermatosis are:
A. Erythematous macules
B. Papules
C. Bullae
D. Vesicles
E. All of the above is true

5. In which layer of the skin are the blisters in the case of pemphigus
vulgaris?
A. Papillary
B. Basal
C. Spinosum
D. Granular
E. Corneum

6. Acantholytic cells by the method of Tzank detected by the study:


A. Histological
B. Bacteriological
C. Cytological
D. Fluorescent
E. Serological

7. Acantholysis is:
A. Melting of intercellular connections in the spinous layer
B. Degenerative changes in the spinous layer
C. Thickening of the stratum corneum
D. Growth of the granular layer
E. Violation of the process of keratinization and preservation of
nuclei in the cells of the stratum corneum

8. Specify the primary morphological element typical of pemphigus


vulgaris:
A. Bullae
B. Microvesicle
C. Papule
D. Urtica
E. Pustula.

9. Bullae in the case of true vesicles are placed:


A. Subcorneally
B. Intraepidermal
C. Subepidermal
D. Subdermally
E. Subhypodermal

10. In the study of Tzank material is stained by the method:


A. Gram
B. Tiel-Nielsen
C. Romanovsky-Gimse
D. Burry
E. Morozov

Standards of answers:: 1 - C. 2 D. 3 B. 4 E. 5 C. 6 C. 7
B. 10 C.
1. Acantholytic cells by the method of Tzank found in:
A. Native culture
B. Histological preparation
C. Smear-imprint
D. Blood tests
E. Serological examination.

2. In the case of localization of rashes with pemphigus vulgaris on the


oral mucosa, histopathological changes (acantholysis) occur in:
A. The granular layer
B. Spiny layer
C. Basal layer
D. Actually the mucous plate
E. Submucosal layer

3. The most typical localization of rashes in pemphigus vulgaris:


A. The scalp
B. Face
C. The mucous membrane of the oral cavity
D. Elbows and knees
E. Palms and soles

4. To confirm the diagnosis of Duhring's herpetiform dermatitis it is


necessary to conduct a skin test to determine hypersensitivity to:
A. Sulfanilamides
B. Antibiotics
C. Novocaine
D. Iodides
E. Bromide
5. What are the characteristics of Duhring's herpetiform dermatitis?
A. Recurrent course
B. Monomorphism of rashes
C. No itching
D. Positive symptom of Nikolsky
E. Frequent lesions of the mucous membranes

6. Bullae in the case of Duhring's dermatitis are placed:


A. Subcorneally
B. Intraepidermal
C. Subepidermal
D. Subdermally
E. Subhypodermal

7. At what bullous dermatosis at patients hypersensitivity to gluten is


quite often observed?
A. Pemphigus vulgaris
B. Exfoliative pemphigus
C. Duhring's dermatitis
D. Stevens-Johnson syndrome
E. Seborrheic pemphigus

8. With Duhring's dermatosis, patients complain of:


A. Pain
B. Itching
C. Feeling of cold extremities
D. The feeling of crawling "ants" on the body
E. Paresthesia

9. Specify the most effective drug for the treatment of pemphigus:


A. Penicillin
B. Sulfadimethoxine
C. Ftivazid
D. Prednisolone
E. Delagil

10. For the treatment of Duhring's herpetiform dermatitis most often


used:
A. Antibiotics
B. Vitamins
C. Antihistamines
D. Preparations of the sulfone series (DDS)
E. Antimalarial drugs

Standards of answers: 1-C. 2-B. 3-C. 4-D. 5- -C. 7-C. 8-B. 9-D. 10-D
1. Average duration of treatment of multibacillary leprosy?
A. 1 year
B. 2 year
C. 3 year
D. Life long

2. The most effective drug against M.leprae is ?


A. Dapsone
B. Rifampicin
C. Clofazimine
D. Prothionamide

3. Multidrug therapy is given for?


A. Syphilis
B. Leprosy
C. Herpetiformis
D. Icthyosis vulgaris

4. All lesions are seen in leprosy except?


A. Erythematous macule
B. Hypopigmented patch
C. Vesicles
D. Flat and raised patches

5. Which pathogen causes leprosy?


A. Mycobacterium tuberculosis
B. Mycobacterium leprae
C. Mycobacterium bovis
D. Mycobacterium africanum

6. Which is other name of leprosy?


A. Lella's disease
B. Giems's disease
C. Hensen's isease

7. Lepromin test help in?


A. In the diagnosis of leprosy
B. In prognosis and classification of leprosy
C. In prognosis

8. The first sensation to be lost in leprosy is?


A. Temperature
B. Pain
C. Both at the same time
D. None

9. In leprosy nerves commonly involved are?


A. High ulnar, low median
B. High median, low ulnar
C. Triple nerve palsy
D. High radial, low median
10. Skin biopsy in leprosy is characterised by?
A. Periappendegial bacilli
B. Periappendegeal lymphocytosis
C. Perivascular lymphocytosis
D. All of the above

Standards of answers: 1 A, 2 B, 3 B, 4- , 5 B, 6 , 7 B, 8 A, 10
D.

1. An 8-year old boy from Bihar presents with a 6 month history of


an ill defined hypopigmented slightly atrophic macule on the face.
What is the most likely diagnosis?
A. Ptyriasis alba
B. Indeterminate leprosy
C. Morphacea
D. Calcium deficiency

2. The following drug is not used for the treatment of type II lepra
reaction (ENL)?
A. Chloroquine
B. Thalidomide
C. Cyclosporine
D. Corticosteroids

3. The main cytokine involved in ENL (Erythema Nodosum


Leprosum) reaction is?
A. Il-2
B. Ifn-Gamma
C. Tnf-Alpha
D. Mcsf
4. The following test is not used for diagnosis of leprosy?
A. Lepromin test
B. Slit skin smear
C. Fnac
D. Skin biopsy

5. A 27 year old patient was diagnosed to have borderline leprosy


and started on Multibacillary multi-drug therapy. Six weeks later, he
developed pain in the nerves and redness and swelling of the skin
lesions. The management of his illness should include all of the
following except?
A. Stop anti-leprosy drugs
B. Systemic corticosteroids
C. Rest to the limbs affected
D. Analgesics

6. Antileprotic drug also used in lepra reaction is ?


A. Rifampicin
B. Dapsone
C. Ciprofloxacin
D. Clofazimine

7. Best method of treatment of ulnar nerve abscess in case of


leprosy is?
A. High doses of steroid
B. Incision and drainage
C. Thalidomide
D. High dose of clofazimine

8. Inverted saucer shaped lesion is found in ?


A. Lepromatous leprosy
B. Tuberculoid leprosy
C. Borderline leprosy
D. Indeterminate leprosy

9. Lepromin test is positive in which leprosy?


A. Lepromatous
B. Indeterminate
C. Histoid
D. Tuberculoid
10. A 16 year old student reported for the evaluation of multiple
hypopigmented macules on the trunk and limbs. All of the following
tests are useful in making a diagnosis of leprosy except?
A. Sensation testing
B. Lepromin test
C. Slit smears
D. Skin biopsy

Standards of answers: 1- B, 2 C, 3 C, 4 A, 5 A, 6 D, 7 B, 8 C,
9 D,
10 B

1. What agent causes syphilis?


A. Pediculus corporis
B. Sarcoptes scabiei varietas hominis
C. Demodexfolliculorum
D. Treponema pallidum
E. Staph ilococcus albus

2. Which one of these diseases refers to classic veneral diseases?


A. Genital warts
B. Chancroid
C. Scabies
D. Pediculosis
E. All the above mentioned

3. The complications of hard chancre include:


A. Mortifying
B. Chancre-amygdalitis
C. Large chancre
D. Chancre-felon
E. Indurative edema

4. Name the atypical forms of primary syphiloma:


A. Balanitis, balanoposthitis
B. Phimosis
C. Indurative edema
D. Chancre-amygdalitis
E. All the above mentioned is true
5. Venereal syphilis in the human host is caused by:
A. Treponema pallidum ssp. endemicum.
B. Treponema pallidum ssp. pallidum (T. pallidum)
C. Treponema pallidum ssp. Pertenue
D. Treponema carateum

6. The most contagious stage of the syphilis is:


A. Primary syphilis
B. Secondary syphilis
C. Tertiary syphilis
D. Early latent syphilis
E. Late latent syphilis

7. Incubation period of primary syphilis is usually about:


A. 1-2 hours
B. 1-2 days
C. 1 week
D. 3 weeks
E. 5-6 months

8. Skin lesion in primary syphilis is:


A. Macule
B. Nodule
C. Vesicle
D. Ulcer
E. Wheal

9. Chancre-amygdalitis (specific amygdalitis) is not characterized:


A. The increase and induration of the amygdala without the
formation of
erosion and ulcer
B. Absence of pain when swallowing
C. Unilateral affection, the absence of violations of the general
state of the body
D. Unilateral affection of submandibular and cervical lymph
nodes
E. Morbidity and bilateral affection

10. Primary period of syphilis lasts for:


A. 7-8 weeks
B. 14 weeks
C. 3-4 weeks
D. 3-4 months
E. 6 months

Standards of answers: 1 D, 2 E, 3 -D, 5 B, 6 A, 7 D, 8 D, 9


C.

1. A 32-year-old man presents with a 4-day history of painless


penile lesions. His sex partners are men and he has had 2 partners in
the last 6 months. Physical examination reveals 3 non-tender ulcers on
the lateral aspect of the penile shaft and firm lymphadenopathy in the
right inguinal region that is nontender. Oral examination and skin
inspection are normal. He has no neurologic symptoms. A clinical
diagnosis of syphilis is strongly suspected; nontreponemal and
treponemal serologic tests for syphilis are ordered. Based on the
information at this point, how would you clinically stage syphilis in
this man?
A. Primary syphilis
B. Secondary syphilis
C. Early latent syphilis
D. Late latent syphilis

2. The duration of latency in Latent syphilis is defined by:


A. An information received from a patient
B. A previous negative STS
C. 1 year
D. A previous negative STS 6 months
E. A previous negative STS 1 year

3. Everything A 25-years old female patient complains of swelling


of the right large pudental lip and discomfort. The general condition of
the
swelling of the right large pudental lip. It is thick, non-sensitive on
palpation, with a dark-red and clear borders. The right-hand
lymphadenitis is present too. Wassermann reaction is negative. What
is a possible diagnosis?
A. Limited elephantiasis
B. Unilateral bartholinitis
C. Indurative edema

E. Cold abscess
4. Patient of the dermato-venereological department with a diagnosis
of "primary seropositive syphilis" was treated with penicillin. 9
hours after the first injection a patient's body temperature rose to
38.2 °C, malaise, headache, and the maculopapular rash on skin
appeared. How can these symptoms be explained?
A. As allergic reaction
B. As toxic reaction
C. As idiosyncratic reaction
D. As infectious disease
E. As viral disease

5. A 32 years old woman complaining of neck pathology turned to


the otolaryngologist. During examination: unilateral increase of the
left amygdala, which caused no pain when touching to it with a spatula.
The patient can not connect this kind of pathology with anything.
Which is the most probable disease:
A. Bartholinitis
B. Seropositive primary syphilis, chancre-amygdalitis
C. Seronegative primary syphilis, typical hard chancre
D. Seropositive primary syphilis, indurative edema
E. Catarrhal angina

6. A 45-year-old man is screened for syphilis and has a positive


Treponema pallidum-specific enzyme-linked immunoassay (EIA). The
laboratory performs a reflexive Rapid Plasmin Reagin (RPR) test that
is nonreactive. Tests for HIV, Neisseria gonorrhoeae, and Chlamydia
trachomatis are negative. He has no medical problems, takes no
medications, and does not use illicit drugs. He has been sexually active
with the same female partner for the past 3 years. He has no prior
history of any sexually transmitted infections, and has never been
tested or treated for syphilis. He is asymptomatic and the physical
examination is normal.
A. What is most appropriate next step in the management of this
man?
B. Repeat both the EIA and the RPR
C. Send an alternative nontreponemal test
D. Send an alternative treponemal test
E. further work-up at this time

A. A 29-year-old woman is seen in an STD clinic with vaginal


discharge and is diagnosed and treated for chlamydia. Laboratory
studies sent at that time show a positive treponemal enzyme
immunoassay (EIA) and a positive Venereal Disease Research
Laboratory (VDRL) test at a titer of 1:16. She has had four male sex
partners in past 3 years. She had a negative syphilis VDRL test 5 years
ago when she was pregnant, but has not had any additional syphilis
testing until now. She has never been treated for syphilis and has no
past or current signs or symptoms consistent with syphilis. Her
physical examination is normal and a pregnancy test is negative. She
does not have any antibiotic allergies. What is the best therapy for this
woman?
A. No treatment is necessary
B. Benzathine penicillin G 2.4 million units intramuscularly in a
single dose
C. Benzathine penicillin G 7.2 million units total, administered as
3 doses of 2.4 million units IM each at 1-week intervals
D. Ceftriaxone 1 g daily either IM for 10 days

B. A 42-year-old man is diagnosed with primary syphilis based on


a non-painful genital ulcer and positive syphilis serologic tests. He
reports one new male and one female sex partner in the past 90 days.
Both partners are contacted and instructed to come to the clinic for
evaluation. The female partner reports sexual contact with the 42-
year-old man about 3 weeks ago. She has no symptoms and says she
had negative testing for bacterial sexually transmitted infections
(STIs) and HIV about 6 months ago. She does not have any antibiotic
allergies. What would you recommend for this woman specifically
related to management of her as a syphilis contact?
A. She does not need further evaluation or treatment at this
time since she is asymptomatic
B. Order serologic tests for syphilis and treat only if the syphilis
test is positive
C. Order serologic tests for syphilis and treat with
intramuscular benzathine penicillin G 2.4 million units in a
single dose before results return
D. Because the exposure occurred 3 weeks ago, defer serologic
testing for syphilis for 3 more weeks and treat only if the
syphilis test is positive

C. A boy A 31-year-old man with HIV who is on antiretroviral


therapy with a CD4 count of 370 cells/mm3 and an HIV RNA level less
than 40 copies/mL presents with a painless ulcer in his perirectal area.
He was last tested for sexually transmitted diseases, including
Neisseria gonorrhea, Chlamydia trachomatis, and syphilis 12 weeks
ago and all test results were negative. His repeat laboratory results on
the most recent visit have returned with a positive rectal gonorrhea
nucleic amplification test, a positive treponemal enzyme
immunoassay (EIA), and a positive Rapid Plasmin Reagin (RPR) test
with a titer of 1:128. He has never been previously diagnosed with or
treated for syphilis. He has no neurologic or ocular symptoms.
Treatment for rectal gonorrhea is ordered. What is the recommended
treatment of syphilis in this man with HIV?
A. Amoxicillin 500 mg orally three times a day for 7 days
B. Azithromycin 2 grams orally once
C. Benzathine penicillin G 2.4 million units intramuscular in a
single dose
D. Benzathine penicillin G 7.2 million units total, administered
as 3 doses of 2.4 million units intramuscular each at 1-week
intervals

D. A 25-year-old man presents for evaluation of new nontender


penile lesion. He has no other symptoms. He has no medical problems,
denies medications or illicit drugs and has no antibiotic allergies. He
reports insertive-only anal intercourse with multiple male partners
and rare condom use. Physical examination reveals a 1 cm, nontender
ulcer on the dorsal surface of his penis and no other significant
findings. Further testing reveals a positive syphilis enzyme
immunoassay (EIA) and a positive Rapid Plasma Reagin (RPR) at a
titer of 1:32. He has never been diagnosed with or treated for syphilis
in the past. An HIV test returns negative.
A. What is the appropriate therapy for this man?
B. Amoxicillin 500 mg orally three times a day for 7 days
C. Azithromycin 2 grams orally once
D. Benzathine penicillin G 2.4 million units intramuscular in a
single dose
E. Benzathine penicillin G 7.2 million units total, administered
as 3 doses of 2.4 million units intramuscular each at 1-week
intervals

Standards of answers: 1 A, 2 B, 3 C, 4 B, 5 B, 6 D, 7 C, 8 C,
9 C, 10 D.
1. A specific lesion of secondary syphilis is:
A. Chancres
B. Syphilids
C. Gumma
D. Syphilitic granuloma
E. Ulcers

2. A 22-year-old female patient, single, complains of skin rash on the


trunk and extremities without subjective sensations. Objective data:
the general condition of the patient is satisfactory, the body

cm in diameter without a tendency to consolidation on the skin of the


trunk, upper and lower extremities. Genital organ examination: a
round ulcer with firm borders, painless, in the stage of epithelization
is found on the skin of the right vulvar lip; moderate polyadenitis.
There is an enlarged (to 1,5 cm) painless and movable on palpation
lymph node in the right inguinal region. What is the provisional
diagnosis for this patient?

A. Epidermoid cancer
B. Primary syphilis
C. Soft chancre
D. Chancriform pyoderma
E. Secondary syphilis

3. A 25-year-old female patient, single, complains of hoarseness, which


appeared without any causes. The patient does not smoke. She saw a

without any treatment. Objective data: the general condition of the


patient is satisfactory, the body tempera
(up to 1 cm in diameter) pale pink spots, which disappear when one
presses with a slide on the lateral surfaces of the trunk. On the left
vulvar lip there is a fresh scar (of round shape, 0.7 cm in diameter). An
examination of the pharynx showed that the tonsil mucosa is red with
a copper tint. The focus has clear borders without purulent
incrustation. There is a moderate polyadenitis. What is the provisional
diagnosis of this patient?
A. Epidermoid cancer
B. Secondary syphilis
C. Soft chancre
D. Chancriform pyoderma
E. Erythema nodosum

4. A patient is a 21-year-old pregnant woman. Her syphilis tests are


strong positive. Objective data: condylomata lata in the perineum
region, single grouped maculopapular spots of the upper trunk,
syphilitic leukoderma of the neck. The viscera and neurologic system
are not affected. What stage of syphilis is observed in this patient?
A. Secondary recurrent syphilis
B. Latent syphilis
C. Primary seropositive syphilis
D. Tertiary syphilis
E. Early secondary syphilis

5. From 2000-2020, what has been the trend in the overall annual
number of cases of syphilis?
A. Increased
B. Decreased
C. Stayed about the same
D. Increased for first 5 years, then steadily decreased

6. A 19-year-old woman presents for a new maculopapular rash on her


trunk, which includes the palms of her hands and soles of her feet. She
has no other medical problems, takes no medications, and denies illicit
drug use. She has never been tested for sexually transmitted infections
(STIs) before. She has had three male partners in the past 6 months
with intermittent condom use. One of her male partners also has sex
with men. A clinical diagnosis of secondary syphilis is make and
laboratory testing is ordered to confirm the diagnosis of syphilis.
Which one of the following is TRUE regarding the laboratory diagnosis
of syphilis in this woman?
A. Approximately 50% of persons with secondary syphilis have a
negative B. Treponema pallidum enzyme immunoassay (EIA)
C. The degree of elevation in the enzyme immunoassay (EIA) titer
can accurately distinguish primary from secondary syphilis
D. A reactive treponemal test does not require any further
confirmatory testing
E. A reactive nontreponemal test should be confirmed by a
treponemal test

7. In the case of syphilitic lesion of placenta the significant alterations


are observed:
A. In maternal placenta
B. In fetal placenta
C. The significant alterations are not observed
D. All mentioned above is correct
E. All mentioned above is false

8. Which of the following does not refer to the probable signs of the
late congenital syphilis:
A. The shortcut little finger
B. Parenchymatous keratitis
C. The absence of xiphoid process
D. Dental dystrophies
E. "Olympian" forehead.

9. A 69-year-old male patient complains of an ulcer of the penis.


Objective data: a round ulcer with clear margins and a smooth bottom
is on the skin of the glans penis. It has a freshly color with gray-
yellowish bloom in the center. The skin around the ulcer is without any
changes. One can palpate swollen lymph nodes in the right inguinal
region, they are painless and movable. There are a lot of small pink
spots on the upper trunk, which do not bother the patient. What is a
possible diagnosis?
A. Secondary syphilis
B. Primary syphilis
C. Epithelioma spinocellulare
D. Chancriform pyoderma
E. Scabies

10. A 30-year-old male patient complains of head and eyebrow hair


loss that begun 2 weeks ago without any cause. The patient has no
somatic pathologies. Objective data: multiple small foci of hair loss and
round foci of sparse hair on the back of the head and temporal areas.
The skin n these foci is without any changes. There are some lenticular
thickened copper-colored papules on the skin of the upper trunk
without any inflammatory changes around them. What is your
preliminary diagnosis?
A. Alopecia areata
B. Seborrheic alopecia
C. Secondary syphilis
D. Trichophytosis capitis
E. Lichen ruber planus
Standards of answers: 1 B, 2 E, 3 B, 4-A, 5 A, 6 D, 7 B, 8 B, 9 A, 10
C.

7. A 30-year-old man presents for follow-up of a positive syphilis


serologic test result. Recent laboratory studies from a routine visit 10
days ago show a positive treponemal enzyme immunoassay (EIA) and
a positive Rapid Plasma Reagin (RPR) with a titer of 1:256. He had a
negative HIV-1/2 antigen-antibody test and is taking tenofovir DF-
emtricitabine for HIV preexposure prophylaxis (PrEP). He has routine
STD testing every 3 months. His serologic tests for syphilis have
always been negative. He denies any genital ulcers or skin
manifestation. Upon further inquiry, he reports he has had blurry
vision in the right eye over the past 4 days. Which one of the following
is a correct statement about the manifestations of ocular syphilis?
A. All persons with ocular syphilis have neurosyphilis
B. Uveitis is the most common manifestation of ocular syphilis
C. Corneal lesions are the most common manifestation of ocular
syphilis
D. Retinal necrosis is the most common manifestation of ocular
syphilis

8. A patient is a 40-year-old man. Blood investigation: Wasserman


reaction and TPI test are positive. There are no changes of the skin,
viscera or neurologic system. What is a probable diagnosis of this
patient?
A. Latent recurrent syphilis
B. Primary seropositive syphilis
C. Secondary recurrent syphilis
D. Tertiary syphilis
E. Early latent syphilis

9. A 42-year-old male patient complains of skin rash without any


subjective sensations. Objective data: multiple pink spots up to 0.3-0.7
cm in size on the skin of the upper trunk and extremities; the surface
of the spots is not desquamated. Besides, they are separated.
Polyadenitis is observed. There is an erosion at the stage of
epithelization on the prepuce. What is a possible diagnosis?
A. Epidemic typhus
B. Secondary latent syphilis
C. Typhoid fever
D. Medicamentous toxicoderma (drug eruption)
E. Secondary recurrent syphilis

10. A mass health examination in an orphanage discovered a boy


with deviations in the physical and mental development. Objective
da
enlarged; the boy has a brachicephalic skull, a saddle-shaped nose, a

diagnosis?
A. Late latent syphilis
B. Early congenital syphilis
C. Latent congenital syphilis
D. Tertiary syphilis
E. Late congenital syphilis

11. A 31-year-old male presents to his primary care medical


provider for evaluation of a rash. He denies taking any new
medications, but reports three new male sexual partners in the last 8
weeks. The rash began several days prior as an erythematous,
maculopapular rash on the chest and back and now it also involves the
palms and soles. He does not have any ocular or neurologic symptoms.
Serologic testing for syphilis is ordered. What is the most appropriate
treatment of this patient with presumed secondary syphilis?
A. Azithromycin 2 grams orally once
B. Doxycycline 100 mg orally twice daily x 28 days
C. Benzathine penicillin G 2.4 million units intramuscular in a
single dose
D. Benzathine penicillin G 7.2 million units total, administered as 3
doses of 2.4 million units given at 1-week intervals

12. A 47-year-old man is clinically diagnosed with secondary


syphilis and treated with benzathine penicillin G 2.4 million units
intramuscular (IM) in a single dose. Their lab test results return with
a positive syphilis enzyme immunoassay (EIA) and a positive Rapid
Plasma Reagin (RPR) at a titer of 1:128. Their HIV test is negative.
Follow-up RPR testing at 6 months shows an RPR titer of 1:4.
A. What would you recommend as the next course of action
regarding management of syphilis for this individual?
B. Treat with a single dose of intramuscular benzathine penicillin
G 2.4 million units
C. Treat with benzathine penicillin G 7.2 million units total,
administered as 3 intramuscular doses of 2.4 million units
given at 1-week intervals
D. Perform a lumbar puncture and cerebrospinal fluid analysis
and treat based on these findings
E. No further treatment is necessary at this time and lumbar
puncture is not indicated

13. A 24-year-old man presents with a 3-day history of a diffuse


rash. He reports having 7 sex partners, within the last 3 months.
Physical examination shows an erythematous macular rash on his
chest, back, arms, and palms. He has no visual or neurologic
complaints and a neurologic examination is normal. A clinical
diagnosis of secondary syphilis is made. Laboratory studies are
ordered and he is treated with a single intramuscular dose of 2.4
million units of benzathine penicillin G. Subsequently, the baseline
laboratory studies show a positive treponemal enzyme immunoassay
(EIA), a Rapid Plasma Reagin (RPR) titer of 1:512, and a negative HIV-
1/2 antigen-antibody test.
A. When should repeat syphilis serologic evaluation be
performed?
B. No follow-up is needed since he received recommended
therapy
C. 6 and 12 weeks
D. 6 and 12 months
E. 12 and 24 months

14. A 25-year-old man is diagnosed with secondary syphilis based


on a diffuse maculopapular rash and a Rapid Plasma Reagin (RPR) titer
of 1:256. He is given an intramuscular dose of 2.4 million units of
benzathine penicillin G in the clinic, but approximately 4 hours after
receiving the dose of penicillin, he returned with complaints of fever,
headache, myalgia, dizziness, and intensification of his rash. Physical
examination shows a temperature of 38.5°C, blood pressure 96/74
mmHg, accentuation of the rash, but no evidence of hives,
oropharyngeal swelling, or wheezing.

symptoms?
B. Mild type IV anaphylactic reaction to penicillin
C. Allergic reaction to benzathine
D. Prozone reaction
E. Jarisch-Herxheimer reaction

15. A 43-year-old man with a positive Rapid Plasma Reagin (RPR)


test (titer of 1:64) is referred for further evaluation and treatment of
syphilis. He reports having a total body rash and low-grade fever that
resolved about 3 months prior. He reports severe headaches in the
past week with nausea, vomiting, and mild photophobia. The headache
has not resolved with over-the-counter medications and he has no
history of headaches. He has not had prior testing or treatment for
syphilis. A recent HIV antigen-antibody test is negative. A lumbar
puncture is performed, with cerebrospinal fluid analysis, to evaluate
for neurosyphilis. Which one of the following statements is TRUE
regarding cerebrospinal fluid (CSF) laboratory studies in diagnosing
neurosyphilis?
A. The CSF Venereal Diseases Research Laboratory (VDRL) test
is highly specific; it is the preferred test for confirming a
suspected diagnosis of neurosyphilis
B. The CSF Rapid Plasma Reagin (RPR) test is the most sensitive
and specific test for diagnosing neurosyphilis; it is the
preferred test both for confirming and excluding
neurosyphilis
C. The CSF fluorescent treponemal antibody absorbed (FTA-
ABS) test has poor sensitivity and no role in diagnosing
neurosyphilis
D. There is no role for CSF treponemal or nontreponemal tests
in diagnosing neurosyphilis

16. A 22-year-old woman is diagnosed with neurosyphilis after


presenting with stroke-like symptoms and a positive treponemal
enzyme immunoassay (EIA) and a positive Rapid Plasma Reagin (RPR)
test (titer of 1:128). A lumbar puncture is performed with
cerebrospinal fluid analysis that shows protein of 64 mg/dL, white
blood cell count of 18 (80% lymphocytes), a red blood cell count of 0,
and a positive Venereal Disease Research Laboratory (VDRL) titer of
1:64. Tests for other causes of stroke, as well as an HIV test are
negative. She has a 2-year history of engaging in transactional sex, but
has never previously been tested or treated for syphilis. She denies
any history of allergic reactions to antibiotics. What is the most
appropriate antimicrobial therapy for treatment of neurosyphilis in
this woman?
A. Ceftriaxone 1 g intramuscular once daily for 5 days, followed
by doxycycline 100 mg orally twice daily for 14 days
B. Ceftriaxone 1 g intramuscular once daily for 10 to 14 days
C. Benzathine penicillin G 7.2 million units total, administered
as 3 doses of 2.4 million units intramuscular each at 1-week
intervals
D. Aqueous crystalline penicillin G 18 to 24 million units per
day, administered as 3 to 4 million units intravenous every 4
hours (or continuous infusion), for 10 to 14 days

Standards of answers: 1 A, 2 C, 3 E, 4 E, 5 C, 6 E, 7 D, 8 E,
9 A, 10 D.
Home / My courses / Dermatology,_venerology
/ 5. Keratomycosis and tinea pedis: clinical features, laboratory examination, prevention and treatment. Trichomycosis: microsporia,
trihophytosis, favus. Clinical features, laboratory examination, prevention and treatment
/ Topic 5. Keratomycosis. Trichomycosis.

Started on Friday, 29 October 2021, 10:00 AM


State Finished
Completed on Friday, 29 October 2021, 10:04 AM
Time taken 4 mins 6 secs
Marks 1.35/1.35
Grade 5.00 out of 5.00 (100%)

Question 1 What pathogen causes epidermophytia of the feet?


Complete

Mark 0.15 out Select one:


of 0.15
a. Pityrosporum orbiculare

b. Trich. mentagrophytes var. interdigital

c. Trich.verrucosum

d. Microsporum canis

e. Trich. rubrum

Question 2 Indicate the most important clinical sign of microsporia of the scalp.
Complete

Mark 0.15 out Select one:


of 0.15
a. Scales

b. Hyperemia

c. Crusts

d. Focal nature of the lesion

e. Broken hairs

Question 3 What pathogen causes infiltrative-suppurative trichophytia (kerion)?


Complete

Mark 0.15 out Select one:


of 0.15
a. Trich. violaceum

b. Trich.verrucosum

c. Microsporum canis

d. Trich. rubrum

e. Pityrosporum orbiculare
Question 4 What pathogen causes anthropophilic microsporia?
Complete

Mark 0.15 out Select one:


of 0.15
a. Pityrosporum orbiculare

b. Trich. mentagrophytes

c. Microsporum ferrugineum

d. Candida albicans

e. Trich. rubrum

Question 5 Concomitant diseases that are most common in children with candidiasis are:
Complete

Mark 0.15 out Select one:


of 0.15
a. Purulent otitis and chronic tonsillitis

b. Asthmoid bronchitis

c. Everything is listed

d. Chronic recurrent acute respiratory viral infections, bronchitis, pneumonia

e. Atopic dermatitis

Question 6 What pathogen Pytiriasis versicolor?


Complete

Mark 0.15 out Select one:


of 0.15
a. Trich. rubrum

b. Candida albicans

c. Pityrosporum orbiculare

d. Pityrosporum ovale

e. Microsporum canis

f. Trich. mentagrophytes

Question 7 What methods are used to diagnose Pytiriasis versicolor?


Complete

Mark 0.15 out Select one:


of 0.15
a. All answers are correct

b. Microscopic examination

c. Benier's symptom method (chip phenomenon)

d. Luminescent method using a Wood lamp

e. Balzer test with iodine tincture


Question 8 For which disease is the pathognomonic iodine test of Balzer?
Complete

Not graded Select one:


a. Inguinal epidermophytia

b. Candidiasis

c. Pytiriasis versicolor

d. Rubrophytia

e. Microsporia

Question 9 What elements of the rash are characteristic of Pytiriasis versicolor?


Complete

Mark 0.15 out Select one:


of 0.15
a. Pustule

b. Papule

c. Nodule

d. Macule

e. Vesicle

Question 10 In the treatment of microsporia of the scalp griseofulvin prescribed in a dose of:
Complete

Mark 0.15 out Select one:


of 0.15
a. 22 mg per kg of body weight three times a day

b. 2 mg per reception

c. 22 mg per day

d. 22 mg three times a day

e. 22 mg per kg of body weight per day

Methodological recommendations
◀︎ Psoriasis Jump to...
▶︎
Home / My courses / Dermatology,_venerology
/ 6. Dermatitis, toxicoderma, eczema, neurodermatitis. Clinical course of allergodermatosis, diagnosis, differential diagnosis,
confirmation of diagnosis and treatment
/ Test-TOPIC 6.

Started on Friday, 29 October 2021, 10:20 AM


State Finished
Completed on Friday, 29 October 2021, 10:38 AM
Time taken 18 mins 5 secs
Marks 17.00/20.00
Grade 4.25 out of 5.00 (85%)

Question 1 4 years old woman consulted the dermatologist about the skin lesions of hands and lower third of the forearm
Complete as a significant swelling, redness, vesiculation. Got ill one week ago. The disease appeared after use of
Mark 1.00 out 'Lotus' washing powder. In the past, the patient has no skin diseases. What is the most likely diagnosis in this
of 1.00 patient:

Select one:
Dyshidrotic eczema
Simple contact dermatitis
Contact allergic dermatitis

Toxicodermatosis

Question 2 Primary morphological element with urticaria is considered:


Complete

Mark 1.00 out Select one:


of 1.00
Macule
Blister
Vesicle
Bulla

Question 3 Contact dermatitis occurs as a result of the impact:


Complete

Mark 1.00 out Select one:


of 1.00
Exogenous factors irritating to the skin
Oral antibiotics

Injectable antibiotics
Inhalation of aerosols
Question 4 Histopathology in acute irritant contact dermatitis:
Complete

Mark 1.00 out Select one:


of 1.00
Epidermal cell necrosis, neutrophils, vesiculation, and necrosis
Spongiosis, lymphocytes and eosinophils in the epidermis, and monocyte and histiocyte infiltration in the
dermis
Acanthosis, hyperkeratosis, lymphocytic infiltrate

Question 5 A boy of 7 years complains of feeling unwell, pain on swallowing, painful rashes on the lips and in the mouth,
Complete itchy rash on the face and body, which appeared three days after receiving Analgin because of acute otitis.
Mark 1.00 out Objectively: the general state of the child is severe; body temperature is 38.6 °C. On the skin of the lips and
of 1.00 oral mucosa, there are common erosions with massive hemorrhagic crusts. On the face and body – multiple
erythematous spots and edematous papules with deep bluish center, on the surface of which there are
vesicles and blisters; the elements tend to be drained. Nickolsky's sign is negative. What kind of emergency
prehospital care should be provided to the child:

Select one:
To prescribe antihistamine drugs, canceling all other drugs
To prescribe corticosteroid ointments, canceling all other drugs

To prescribe corticosteroids orally, canceling all other drugs


To prescribe corticosteroids parenterally, canceling all other drugs

Question 6 How does toxicoderma caused sulfanilamide drugs:


Complete

Mark 1.00 out Select one:


of 1.00
Fixed eruption
Annular erythema
Erythema nodosum
Erythema multiforme exudative

Question 7 What are the primary morphological elements that are not found in allergic contact dermatitis:
Complete

Mark 0.00 out Select one:


of 1.00
Papules, vesicles

Papules, vesicles, wheals


Papules, wheals, erythema
Papules, nodules, wheals, pustulas

Question 8 Specify the method of penetration of the allergen in allergic contact dermatitis in the patient's body:
Complete

Mark 1.00 out Select one:


of 1.00
Inhalation
Transfusion
Transcutaneous

Orally
Question 9 Select the stages of simple contact dermatitis:
Complete

Mark 1.00 out Select one:


of 1.00
Erythematous, vesiculobullous, necrotization
Swelling, multiple sclerosis, atrophy
Erythematous, hyperkeratotic-infiltrative, atrophic

Progressive, regressing, stationary

Question 10 Fixed erythema is not characterized by:


Complete

Mark 1.00 out Select one:


of 1.00
Localization on the skin, genital and oral mucosa
Occurrence as a result of taking sulfonamides, antibiotics etc.
Rash of several red spots 2-5 cm in diameter
Occurrence due to exposure to obligate irritants

Question 11 Lyell's syndrome is characterized by:


Complete

Mark 1.00 out Select one:


of 1.00
Meshcherskiy-Besnier's symptom
Nikolsky's symptom

Auspitz triad
Isomorphic Koebner response

Question 12 Select a positive symptom of the syndrome of Lyell:


Complete

Mark 1.00 out Select one:


of 1.00
"Stearin spot"
Gorchakov-Hardy
"Terminal film"
Nikolsky

Question 13 Which of the following form is not characteristic for eczema:


Complete

Mark 1.00 out Select one:


of 1.00
Microbial

Herpetiformal
Occupational
Idiopathic
Question 14 Characteristic feature of simple contact dermatitis is:
Complete

Mark 0.00 out Select one:


of 1.00
Occurrence only in sensitized patients
Fuzzy boundaries of the lesion
Clear boundaries of the lesion

Occurrence in 12-74 hour after exposure to a certain factor

Question 15 What is characteristic simple contact dermatitis:


Complete

Mark 0.00 out Select one:


of 1.00
Develops under the influence of the stimulus, he entered through the
Developed after dermal contact with an irritant
respiratory tract
Acute inflammation of the mucous membranes
Acute inflammation of the skin

Question 16 2-years old female patient consulted the dermatologist complaining of some rash on the skin of neck and
Complete chest, accompanied by itching. Rash appeared after taking aspirin and kept on the skin for about two hours
Mark 1.00 out and then without any action gradually disappeared appearing at new areas. Objectively, there are multiple
of 1.00 palm-sized urticaria elements. The patient has red dermographism; eosinophilia is revealed in the blood.
What kind of skin disease can be thought of in this case:

Select one:
Eczema

Urticaria
Simple contact dermatitis
Allergic dermatitis

Question 17 The most common form of occupational skin diseases is:


Complete

Mark 1.00 out Select one:


of 1.00
Allergic contact dermatitis
Irritant contact dermatitis
Atopic dermatitis

Nummular eczema

Question 18 Everything mentioned below is specific to allergic contact dermatitis, except:


Complete

Mark 1.00 out Select one:


of 1.00
Margins of lesions are sharp
ACD is due to reexposure to a substance to which the individual is sensitized
Sensibilization
Margination of lesions spreads in the periphery beyond the actual site of exposure
Question 19 Female patient, 37 years old, employed as a manipulative nurse, complains of feeling unwell, weakness,
Complete headache, muscle and joint pain and skin rash, accompanied by severe pain and burning sensation. Some
Mark 1.00 out rash appeared two days after receiving ampicillin because of sore throat. Objectively: general condition of the
of 1.00 patient is severe; body temperature is 39.2 °C. The entire skin is bloodshot. On the trunk and extremities,
there are multiple bullous elements, erosion, fragments of epidermis observed. The skin is painful on
palpation. Nikolsky's sign is positive. What kind of emergency pre-hospital care should not be provided to the
child:

Select one:
To prescribe enterosorbents
Stop taking ampicillin
To prescribe corticosteroids parenterally

To refer the patient to the intensive care unit for further treatment

Question 20 For the treatment of toxicoderma use drugs:


Complete

Mark 1.00 out Select one:


of 1.00
Antihistamines
Antibacterial
Antimycotic
Antiparasitic

◀︎ Methodological recommendations Jump to... Methodological recommendations ▶︎


Home / My courses / Dermatology,_venerology
/ 7. Bullous dermatoses. Clinical course, diagnosis, differential diagnosis, confirmation of diagnosis and treatment. Skin tuberculosis.
Clinical course, diagnosis, differential diagnosis, confirmation of diagnosis and treatment. Determination of quality o
/ Test 1

Started on Friday, 12 November 2021, 9:30 AM


State Finished
Completed on Friday, 12 November 2021, 9:45 AM
Time taken 15 mins 28 secs
Marks 2.85/3.00
Grade 4.75 out of 5.00 (95%)

Question 1 What are the main pathohistological changes in pemphigus vulgaris?


Complete

Mark 0.15 out Select one:


of 0.15
a. Hyperkeratosis

b. Parakeratosis

c. Acantholysis

d. Acanthosis

e. Spongiosis

Question 2 Acantholysis is:


Complete

Mark 0.15 out Select one:


of 0.15
a. Growth of the granular layer

b. Violation of the process of keratinization and preservation of nuclei in the cells of the stratum
corneum

c. Melting of intercellular connections in the spinous layer

d. Thickening of the stratum corneum

e. Degenerative changes in the spinous layer

Question 3 Which is other name of leprosy?


Complete

Mark 0.15 out Select one:


of 0.15
a. Hensen's disease

b. Lella's disease

c. Giems's disease
Question 4 Which pathogen causes leprosy?
Complete

Mark 0.15 out Select one:


of 0.15
a. Mycobacterium leprae

b. Mycobacterium tuberculosis

c. Mycobacterium bovis

d. Mycobacterium africanum

Question 5 Multidrug therapy is given for?


Complete

Mark 0.15 out Select one:


of 0.15
a. Leprosy

b. Herpetiformis

c. Icthyosis vulgaris

d. Syphilis

Question 6 The most important laboratory tests to confirm the diagnosis of pemphigus vulgaris are
Complete

Mark 0.15 out Select one:


of 0.15
a. Blood tests for electrolytes

b. Clinical blood test

c. Investigation of smears-imprints on acantholytic cells

d. Investigation of blister contents for eosinophils

e. Sowing the contents of the blister on the flora

Question 7 In which layer of the skin are the blisters in the case of pemphigus vulgaris?
Complete

Mark 0.15 out Select one:


of 0.15
a. Granular

b. Papillary

c. Basal

d. Corneum

e. Spinosum

Question 8 Lepromin test help in?


Complete

Mark 0.15 out Select one:


of 0.15
a. In prognosis and classification of leprosy

b. In the diagnosis of leprosy

c. In prognosis
Question 9 In leprosy nerves commonly involved are?
Complete

Mark 0.00 out Select one:


of 0.15
a. High radial, low median

b. High median, low ulnar

c. High ulnar, low median

d. Triple nerve palsy

Question 10 In the study of Tzank material is stained by the method:


Complete

Mark 0.15 out Select one:


of 0.15
a. Tiel-Nielsen

b. Romanovsky-Gimse

c. Burry

d. Morozov

e. Gram

Question 11 All lesions are seen in leprosy except?


Complete

Mark 0.15 out Select one:


of 0.15
a. Hypopigmented patch

b. Erythematous macule

c. Vesicles

d. Flat and raised patches

Question 12 Specify the primary morphological element typical of pemphigus vulgaris:


Complete

Mark 0.15 out Select one:


of 0.15
a. Microvesicle

b. Papule

c. Bullae

d. Urtica

e. Pustula
Question 13 Indicate the most important diagnostic symptom to confirm the diagnosis of pemphigus:
Complete

Mark 0.15 out Select one:


of 0.15
a. Nikolsky's symptom

b. Isomorphic reaction

c. Mantoux reaction

d. The Kebner phenomenon

e. Balzer's test

Question 14 The first sensation to be lost in leprosy is?


Complete

Mark 0.15 out Select one:


of 0.15
a. None

b. Temperature

c. Pain

d. Both at the same time

Question 15 Skin biopsy in leprosy is characterised by?


Complete

Mark 0.15 out Select one:


of 0.15
a. Periappendegeal lymphocytosis

b. Periappendegial bacilli

c. All of the above

d. Perivascular lymphocytosis

Question 16 Average duration of treatment of multibacillary leprosy?


Complete

Mark 0.15 out Select one:


of 0.15
a. 3 year

b. 2 year

c. 1 year

d. Life long

Question 17 The most effective drug against M.leprae is ?


Complete

Mark 0.15 out Select one:


of 0.15
a. Dapsone

b. Clofazimine

c. Rifampicin

d. Prothionamide
Question 18 Acantholytic cells by the method of Tzank detected by the study:
Complete

Mark 0.15 out Select one:


of 0.15
a. Fluorescent

b. Histological

c. Bacteriological

d. Cytological

e. Serological

Question 19 The most characteristic morphological elements for Duhring's herpetiform dermatosis are:
Complete

Mark 0.15 out Select one:


of 0.15
a. Bullae

b. Papules

c. Erythematous macules

d. All of the above is true

e. Vesicles

Question 20 Bullae in the case of true vesicles are placed:


Complete

Mark 0.15 out Select one:


of 0.15
a. Subhypodermal

b. Subcorneally

c. Subdermally

d. Intraepidermal

e. Subepidermal

◀︎ Methodological recommendations Jump to... Bullous dermatoses ▶︎


Home / My courses / Dermatology,_venerology
/ 8. Leprosy. Clinical course, diagnosis, differential diagnosis, confirmation of diagnosis and treatment. Viral diseases of the skin and
mucous membranes. Clinical course, diagnosis, differential diagnosis, treatment. Principles of cosmetic skin care
/ Test to control the FINAL LEVEL OF KNOWLEDGE

Started on Friday, 12 November 2021, 9:55 AM


State Finished
Completed on Friday, 12 November 2021, 10:11 AM
Time taken 16 mins 6 secs

Question 1 All are true regarding lepromatous leprosy except


Complete

Marked out of Select one:


0.25
a. presence of granulomas sub dermally

b. presence of globi

c. decreased cell mediated immunity

d. subepidermal free zone

Question 2 In the case of localization of rashes with pemphigus vulgaris on the oral mucosa, histopathological changes
Complete (acantholysis) occur in:
Marked out of
0.25 Select one:
a. Spiny layer

b. The granular layer

c. Actually the mucous plate

d. Basal layer

e. Submucosal layer

Question 3 Acantholytic cells by the method of Tzank found in:


Complete

Marked out of Select one:


0.25
a. Smear-imprint

b. Histological preparation

c. Blood tests

d. Native culture

e. Serological examination
Question 4 A 27 year old patient was diagnosed to have borderline leprosy and started on Multibacillary multi-drug
Complete therapy. Six weeks later, he developed pain in the nerves and redness and swelling of the skin lesions. The
Marked out of management of his illness should include all of the following except?
0.25

Select one:
a. Rest to the limbs affected

b. Stop anti-leprosy drugs

c. Systemic corticosteroids

d. Analgesics

Question 5 Bullae in the case of Duhring's dermatitis are placed:


Complete

Marked out of Select one:


0.25
a. Subcorneally

b. Subepidermal

c. Intraepidermal

d. Subhypodermal

e. Subdermally

Question 6 The main cytokine involved in ENL (Erythema Nodosum Leprosum) reaction is?
Complete

Marked out of Select one:


0.25
a. Ifn-Gamma

b. Mcsf

c. Il-2

d. Tnf-Alpha

Question 7 Best method of treatment of ulnar nerve abscess in case of leprosy is?
Complete

Marked out of Select one:


0.25
a. High doses of steroid

b. Incision and drainage

c. Thalidomide

d. High dose of clofazimine

Question 8 Following test is not used for diagnosis of leprosy


Complete

Marked out of Select one:


0.25
a. fine needle aspiration cytology

b. slit skin smear

c. lepromin test

d. skin biopsy
Question 9 To confirm the diagnosis of Duhring's herpetiform dermatitis it is necessary to conduct a skin test to
Complete determine hypersensitivity to:
Marked out of
0.25 Select one:
a. Sulfanilamides

b. Bromide

c. Antibiotics

d. Novocaine

e. Iodides

Question 10 All of the following are true of tuberculoid leprosy except


Complete

Marked out of Select one:


0.25
a. Treatment for 5 years

b. Positive lepromin test

c. Body immunity is high

d. It’s infective

Question 11 Antileprotic drug also used in lepra reaction is?


Complete

Marked out of Select one:


0.25
a. Clofazimine

b. Ciprofloxacin

c. Dapsone

d. Rifampicin

Question 12 The following test is not used for diagnosis of leprosy?


Complete

Marked out of Select one:


0.25
a. Slit skin smear

b. Fnac

c. Lepromin test

d. Skin biopsy

Question 13 The following drug is not used for the treatment of type II lepra reaction (ENL)?
Complete

Marked out of Select one:


0.25
a. Cyclosporine

b. Corticosteroids

c. Chloroquine

d. Thalidomide
Question 14 Inverted saucer shaped lesion is found in?
Complete

Marked out of Select one:


0.25
a. Lepromatous leprosy

b. Borderline leprosy

c. Tuberculoid leprosy

d. Indeterminate leprosy

Question 15 An 8-year old boy from Bihar presents with a 6 month history of an ill defined hypopigmented slightly
Complete atrophic macule on the face. What is the most likely diagnosis?
Marked out of
0.25 Select one:
a. Calcium deficiency

b. Ptyriasis alba

c. Indeterminate leprosy

d. Morphacea

Question 16 A 16 year old student reported for the evaluation of multiple hypopigmented macules on the trunk and limbs.
Complete All of the following tests are useful in making a diagnosis of leprosy except?
Marked out of
0.25 Select one:
a. Skin biopsy

b. Sensation testing

c. Slit smears

d. Lepromin test

Question 17 Lepromin test is positive in which leprosy?


Complete

Marked out of Select one:


0.25
a. Indeterminate

b. Lepromatous

c. Tuberculoid

d. Histoid

Question 18 The most typical localization of rashes in pemphigus vulgaris:


Complete

Marked out of Select one:


0.25
a. Face

b. Elbows and knees

c. The scalp

d. Palms and soles

e. The mucous membrane of the oral cavity


Question 19 At what bullous dermatosis at patients hypersensitivity to gluten is quite often observed?
Complete

Marked out of Select one:


0.25
a. Stevens-Johnson syndrome

b. Duhring's dermatitis

c. Seborrheic pemphigus

d. Pemphigus vulgaris

e. Exfoliative pemphigus

Question 20 What are the characteristics of Duhring's herpetiform dermatitis?


Complete

Marked out of Select one:


0.25
a. Frequent lesions of the mucous membranes

b. No itching

c. Monomorphism of rashes

d. Recurrent course

e. Positive symptom of Nikolsky

Methodological recommendations
◀︎ Methodological recommendations Jump to...
▶︎
1. The skin consists of the following layers: A.
Basal, spinosum, granular, lucidum, corneum
B. Basal, spinosum, granular, corneum
C. Epidermis, dermis, hypodermis
D. Epidermis, dermis
E. Papillary, reticular

2. The skin appendages include:


A. Sweat and sebaceous glands
B. Nails, hair
C. Blood and lymphatic vessels, nerve endings
D. Nails, hair, sweat and sebaceous glands
E. Hair follicles

3. Terminal hair from root to outer end is formed from:


A. 1 layer
B. 1-2 layers
C. 5 layers D. 3 layers
E. 4 layers

4. Sebaceous glands produce a secret:


A. Sebum
B. Slime
C. Sweat
D. Milk
E. Tears

5. By the nature of the secretion of sweat glands are: A. Holocrine


glands
B. Holocrine and apocrine glands
C. Eccrine and apocrine glands
D. Apocrine glands
E. Eccrine glands

6. The circulatory system of the skin forms:


A. Superficial and deep plexus
B. Superficial plexus
B. Deep plexus
10. Skin functions:
A. Protective
B. Thermoregulation
C. Excretory
D. Sensory
E. All answers are correct
Standards of answers: 1 -C . 2 D. 3 D. 4 C. 6 E. 8
C. 10 E.
1. The symptom characteristic of scabies is:
A. Gorchakov-Ardi
B. Nikolsky
C. Jadasson
D. Kerion-Celsus
E. All answers are correct

2. Balzer's test has valuable diagnostic value at:


A. pityriasis versicolor
B. psoriasis
C. epidermophytia
D. rubromycosis
E. lichen ruber planus

3. The main elements of the skin's immune system are:


A. Langerhans cells
B. T-Lymphocytes
C. Keratinocytes
D. Merkel cells
E. Vater-Pacini corpuscle

4. The nerve endings include: A. Merkel


cells.
B. Greenstein cells.
C. Meissner corpuscle.
D. Langerhans cells.
E. Kupffer cells

5. Kebner's phenomenon:

6. What is the main diagnosis of tuberculosis of the skin?


A. clinical features , course
B. the presence of tuberculosis of the internal organs
C. Mantoux test
D. data of pathohistological research
A. elements of dermatosis are placed linearly at the sites of
excoriation
B. erosion of the oral mucosa
C. all the answers are correct
E. detection of Mycobacterium tuberculosis by PCR
F. all listed.

7. To diagnose demodicosis use:


A. microscopic analysis
B. immunofluorescent diagnosis
C. DNA diagnostics
D. microscopy in the dark field of view.

8. Which of the following is not a morphological element?


A. erythema
B. papule
C. roseola
D. urticaria
E. wetting

9. The symptom of "thimble" is characteristic of:


A. red flat herpes
B. syphilis
C. psoriasis
D. all the answers are correct

10. What is the name of the diagnostic method that allows to


determine the nature of peeling and the density of adhesion of the
scales to the skin surface?
A. dermographism
B. diascopy
C. grattage
D. isomorphic reaction
E. iodine test

Standards of answers: 1- - - - - -F. 7- -E. 9-C. 10-


C
1. The primary cavity elements of the rash include:
A. Pustula
B. Papula
C. Macula
D. Nodule
E. Erosion

2. Limited skin discoloration is called:


A. Papules
B. Pustula
C. Vesicle
D. Macula
E. Erosion

3. The primary cavity-free elements of the rash include:


A. Papules
B. Macula
C. Nodule
D. Tuberculum
E. All answers are correct

4. Clinical evaluation of the elements of skin rash involves all of the


above, except:
A. Determination of the nature of the rash (inflammatory or
noninflammatory)
B. Prevalence of the process
C. Localization
D. Definition of morphological elements
E. Determination of skin vascular reactions

5. Lichenification is characterized by:


A. Sealing and thickening of the skin
B. Pigmentation
C. Enhanced skin pattern
D. All of the above
E. All of the above, except for pigmentation

6. The primary morphological element characteristic of shingles is:


A. Spot
B. Papule and tuberculum
C. Vesicle and bullae
D. Bullae
E. All of the above is true

7. Ointments are prescribed:


A. To insulate the skin from the effects of chemical, mechanical
injuries, friction
B. As emollients
C. As conductors of medicinal substances
D. As those that cleanse the skin of secondary layers
E. All of the above is true

8. A comprehensive clinical examination of the skin includes all of the


above, except A. Grattage (scraping)
B. Palpation
C. Diascopy
D. Measurement of electrical resistance of the skin
E. Measurement of skin temperature

9. Specify the difference between a tuberculum and a papule:


A. Smooth surface
B. Dense consistency
C. The presence of a purulent cavity
D. Scar formation after reverse development
E. Elevation above the level of the skin
10. Inflammatory spot of large size is called:
A. Erythema
B. Hemorrhage
C. Roseola
D. Purpura
E. Leukoderma

Standards of answers1- -D, 3-E, 4-E, 5-D, 6-C. 7-E, 8-D, 9-D, 10-

1. Cavity primary elements are:


A. Urticarial element
B. Vesicle
C. Papule
D. Nodule
E. Tuberculum

2. True polymorphism is:


A. The presence of one variety of primary elements
B. The presence of various primary elements
C. The tendency of elements to merge
D. The presence of various secondary elements
E. The tendency of elements to peripheral growth

3. Ulcer is:
A. Skin defect within the epidermis
B. Skin changes in the case of massive infiltration of its papillary layer
C. The consequence of the growth of the papillary layer of the
dermis with the simultaneous thickening of the spiny layer of the
epidermis
D. Defect of the skin or subcutaneous tissue
4. Hyperkeratosis is:
A. Thickening of the stratum corneum
B. Disruption of the connection between the cells of the spiny layer
C. Acute swelling of the papillae of the dermis
D. Increasing the number of cells in the granular layer
E. Thickening of the spiny layer

5. Vacuol dystrophy is:


A. Disruption of the connection between desmosomes
B. Infiltrate in the superficial parts of the dermis
C. Skin defect within the dermis
D. Accumulation of fluid in the cells of the basal and prickly layers
E. Thickening of the spiny layer

6. In place of the vesicle, the tire of which collapsed, is formed:


A. Scar
B. Ulcer
C. Excoriation D. Erosion
E. Excoriation

7. Name the morphological basis of the tubercle:


A. Acanthosis
B. Perivascular infiltration
C. Vacuol dystrophy
D. Infectious granuloma
E. Papillomatosis

8. The patient was consulted by a patient with complaints of bright


pink, swollen elements, intense itching. 2-3 hours after the
appearance of the elements regress without a trace. Name them:
A. Tubercle
B. Nodule
C. Urticarial element
D. Bullae
E. Vesicle

9. Name the clinical differences between tubercle and papule:


A. Flat shape
B. Dimensions with lentils
C. Ulceration with scarring
D. Soft texture
E. Bluish color

10. Specify the mechanism of formation of intra-epidermal blister:


A. Acantholysis
B. Ballooning dystrophy
C. Vacuol dystrophy
D. Spongiosis
E. Exocytosis

Standards of answers: 1-B, 2-B, 3-D, 4- -D, 6-D, 7-D, 8-C, 9-C, 10-

1. Which of these nosologies are dermatozoonoses?


A. Sycosis
B. Scabies
C. Genital warts D. Molluscum contagiosum
E. Favus.

2. There are the following clinical forms of scabies:


A. Typical
B. Nervous
C. Professional
D. Seborrheic
E. Allergic

3. What elements are considered objective signs of scabies?


A. Tuberculum
B. Nodule
C. Scabetic burrow
D. Papule
E. Crust

4. What causes scabies?


A. Pityrosporum orbiculare
B. Pediculi pubis
C. Microsporum canis
D. Sarcoptes hominis
E. Corynobacteria minutissimum

5. What is the life expectancy of a female scabies mite?


A. 1 day
B. 1 week
C. 8 weeks
D. Six months
E. 1 year

6. What topical treatment are used to treat scabies?


A. Antibacterial ointments
B. Antifungal ointments
C. Antiparasitic ointments
D. Corticosteroid ointments
E. Keratoplastic ointments

7. Which of the following pathogens is the main etiological factor in


furunculosis? A. Pediculus pubis
B. Sarcoptes hominis
C. Staphylococcus
D. Streptococcus
E. Corynobacteria minutissimum

8. Which of the following pathogens is the main etiological factor in


hydradenitis? A. Pediculus pubis
B. Sarcoptes hominis
C. Staphylococcus
D. Streptococcus
E. Corynobacteria minutissimum
9. For streptococcal impetigo is characterized by all of the above,
except:
A. Appearances of phlycten on the skin
B. Yellow crusts
C. Rapid spread
D. Inflammatory nodes
E. Inflammatory rim around the phlycten

10. Purulent inflammation of the apocrine glands is observed in:


A. Furunculosis;
B. Sycosis vulgaris
C. Ecthyma vulgaris
D. Hydradenitis
E. Finger's pseudofurunculosis

Standards of answers: 1 - B. 2 D. 4 D. 5 C. 6 C. 7 C. 8
C. 9 D. 10 D.

1. The most typical terms of the incubation period of scabies:


A. 2-5 days
B. 7-10 days
C. 40-50 days
D. More than two months
E. Half a year

2. The rate of scabies generalization depends on all these factors,


except:
A. The number of mites that got on the skin at the time of infection
B. Sexual and age characteristics of the skin
C. Level of itchiness
D. Hygienic skills
E. The state of immunity

3. Scabies is characterized by:


A. Lenticular papules
B. Hemorrhage
C. Dotted itchy vesicles and papules
D. Urticaria
E. Polygonal papules

4. Indicate the location of typical localization of scabies in adults?


A. The scalp
B. Face and neck
C. Spina
D. Palms and soles
E. Interdigital folds of the hands

5. What is the most common complication of scabies?


A. Secondary pyoderma
B. Sepsis
C. Cicatricial atrophy of the skin
D. Phlegmon
E. All of the above

6. In what forms of pyoderma phlycten is the main element of the rash?


A. Vulgar sycosis
B. Hydradenitis
C. Furunculosis
D. Vulgar impetigo
E. Osteofolliculitis

7. Which of the following applies to superficial streptoderma?


A. Vulgar sycosis
B. Furuncle
C. Hydradenitis
D. Carbuncle
E. None of the above

8. The patient complains of general malaise, headache, painful


swelling on the back of the neck, which is a dense, painful coneshaped
node, in the center - a necrotic rod. The skin around him is swollen,
infiltrated, red, hot to the touch. Your diagnosis.
A. Furuncle
B. Gummous syphilis
C. Colliquative tuberculosis
D. Hydradenitis
E. Carbuncle

9. In case of furunculosis obligatory examination includes:


A. Blood sugar level
B. Blood for bilirubin
C. Urine for creatinine
D. Feces for helminths
E. All of the above

10. The patient, 25 years old, complains of rashes in the interdigital


folds, in the area of the wrists, genitals, abdomen, which are
accompanied by severe itching, especially at night. Objectively: on the
background of unaffected skin, multiple rashes are represented by
papular and papulovesicular rashes in pairs, and excoriations. The
back is free from rashes. Your diagnosis:
A. Scabies
B. Herpes
C. Eczema
D. Neurodermatitis
E. Epidermophytia

Standards of answers: 1-B. 2-B. 3-C. 4-E. 5- -D. 7-E. 8- - -

1. The main parameters for the differential diagnosis of psoriasis are:


A. The primary morphological element of the rash
B. Form of rash

D. The nature and location of peeling


E. Subjective feelings
F. All answers are correct

2. Name the main pathohistological changes in psoriasis:


A. Granulosis;
B. Hyperkeratosis, parakeratosis, acanthosis
C. Parakeratosis, acanthosis
D. Acanthosis
E. Polymorphic-cellular infiltration.
3. Clinical forms of psoriasis include:
A. Limited psoriasis
B. Psoriatic arthropathy
C. Sclero-atrophic psoriasis
D. Common psoriasis

4. Seasonal forms of psoriasis are:


A. Winter
B. Mixed
C. Early
D. Congenital
E. Autumn

5. List the clinical variants of lichen ruber planus:


A. Annular form
B. Erosive-ulcerative
C. Hypertrophic form
D. Bullous form
E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:


A. The presence of new papular rashes
B. The presence of a tendency to peripheral growth
C. Auspitz's positive psoriatic triad
D. Positive symptom of Koebner
E. Erythroderma

7. With what diseases it is necessary to carry out differential


diagnosis at suspicion of existence at the patient of a lichen ruber
planus?
A. Psoriasis
B. Dermatomycosis
C. Diffuse neurodermatitis
D. Toxicoderma
E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?


A. The form of papules is miliary
B. Inflammatory papules
C. Non-inflammatory papules
D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:


A. No itching
B. Itchy skin only at night
C. The appearance of rashes only on the extensor surfaces of the
extremities
D. Wickham's symptom
E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:

A. UVI (ultraviolet irradiation)


B. Balneotherapy
C. PUVA - therapy
D. UHF therapy (ultra-high frequency)
E. All answers are correct
Standards of answers: 1 - F. 2 B. 3 B. 4 F. 6 C. 7
B. 9 D. 10 E.

1. Choose the diagnostic phenomena characteristic of psoriasis:


A. The Kebner phenomenon
B. Symptom of stearin stain
C. Symptom of the terminal film
D. Symptom of Auschpitz
E. All answers are correct

2. Choose a symptom pathognomonic for LRP:


A. Nikolsky's symptom
B. Benier-Meshchersky's symptom
C. Wickham's symptom
D. Symptom Gorchakov-Ardi
E. Yadasson's symptom

3. For the local treatment of psoriasis use:


A. Lorinden ointment - A
B. 2% salicylic ointment
C. 3% naphthalene ointment
D. Dermovate
E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:


A. The elements are completely covered with silvery-white scales
B. On the periphery of the papules -
C. The appearance of new rashes
D. Peripheral growth of elements
E. Pale pink color of rash elements

5. For the regressive stage of psoriasis is characterized by:


A. Around the elements -
B. Disappearance of rashes
C. Pale color of the rash elements
D. Disappearance of scales from the surface of psoriatic rashes
E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?
A. flexion surface of the extremities
B. extensor surface of the extremities
C. interdigital spaces
D. skin around physiological openings
E. genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?


A. psoriatic triad
B. the Kebner phenomenon
C. Symptom of Auspices
D. the phenomenon of "blood dew"
E. the phenomenon of "apple jelly"
8. What clinical sign is not characteristic of the progressive stage of
psoriasis?
A. tendency to merge
B. the presence of a psoriatic triad
C. silvery-white peeling in the center of the papule
D. the Kebner phenomenon
E. silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?


A. yellow-red color
B. umbilical indentation in the center of the papule
C. oval shape
D. the surface is covered with white scales
E. shiny surface

10. Clinical varieties of psoriasis do not include:


A. seborrheic
B. leaf-like
C. exudative
D. vulgar
E. rupee

Standards of answers: 1-E. 2-C. 3-E. 4- -E. 6-B. 7-E. 8-E. 9-D. 10-B

1. The main parameters for the differential diagnosis of psoriasis are:


A. The primary morphological element of the rash
B. Form of rash

D. The nature and location of peeling


E. Subjective feelings
F. All answers are correct

2. Name the main pathohistological changes in psoriasis:


A. Granulosis;
B. Hyperkeratosis, parakeratosis, acanthosis
C. Parakeratosis, acanthosis
D. Acanthosis
E. Polymorphic-cellular infiltration.

3. Clinical forms of psoriasis include:


A. Limited psoriasis
B. Psoriatic arthropathy
C. Sclero-atrophic psoriasis
D. Common psoriasis

4. Seasonal forms of psoriasis are:


A. Winter
B. Mixed
C. Early
D. Congenital
E. Autumn

5. List the clinical variants of lichen ruber planus:


A. Annular form
B. Erosive-ulcerative
C. Hypertrophic form
D. Bullous form
E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:


A. The presence of new papular rashes
B. The presence of a tendency to peripheral growth
C. Auspitz's positive psoriatic triad
D. Positive symptom of Koebner
E. Erythroderma

7. With what diseases it is necessary to carry out differential


diagnosis at suspicion of existence at the patient of a lichen ruber
planus?
A. Psoriasis
B. Dermatomycosis
C. Diffuse neurodermatitis
D. Toxicoderma
E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?


A. The form of papules is miliary
B. Inflammatory papules
C. Non-inflammatory papules
D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:


A. No itching
B. Itchy skin only at night
C. The appearance of rashes only on the extensor surfaces of the
extremities
D. Wickham's symptom
E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:

A. UVI (ultraviolet irradiation)


B. Balneotherapy
C. PUVA - therapy
D. UHF therapy (ultra-high frequency)
E. All answers are correct
Standards of answers: 1 - F. 2 B. 3 B. 4 F. 6 C. 7
B. 9 D. 10 E.
1. Choose the diagnostic phenomena characteristic of psoriasis:
A. The Kebner phenomenon
B. Symptom of stearin stain
C. Symptom of the terminal film
D. Symptom of Auschpitz
E. All answers are correct

2. Choose a symptom pathognomonic for LRP:


A. Nikolsky's symptom
B. Benier-Meshchersky's symptom
C. Wickham's symptom
D. Symptom Gorchakov-Ardi
E. Yadasson's symptom
3. For the local treatment of psoriasis use:
A. Lorinden ointment - A
B. 2% salicylic ointment
C. 3% naphthalene ointment
D. Dermovate
E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:


A. The elements are completely covered with silvery-white scales
B. On the periphery of the papules -
C. The appearance of new rashes
D. Peripheral growth of elements
E. Pale pink color of rash elements

5. For the regressive stage of psoriasis is characterized by:


A. Around the elements -
B. Disappearance of rashes
C. Pale color of the rash elements
D. Disappearance of scales from the surface of psoriatic rashes
E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?
A. flexion surface of the extremities
B. extensor surface of the extremities
C. interdigital spaces
D. skin around physiological openings
E. genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?


A. psoriatic triad
B. the Kebner phenomenon
C. Symptom of Auspices
D. the phenomenon of "blood dew"
E. the phenomenon of "apple jelly"

8. What clinical sign is not characteristic of the progressive stage of


psoriasis?
A. tendency to merge
B. the presence of a psoriatic triad
C. silvery-white peeling in the center of the papule
D. the Kebner phenomenon
E. silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?


A. yellow-red color
B. umbilical indentation in the center of the papule
C. oval shape
D. the surface is covered with white scales
E. shiny surface

10. Clinical varieties of psoriasis do not include:


A. seborrheic
B. leaf-like
C. exudative
D. vulgar
E. rupee

Standards of answers: 1-E. 2-C. 3-E. 4- -E. 6-B. 7-E. 8-E. 9-D. 10-B

1. For which disease is the pathognomonic iodine test of Balzer?


A. Microsporia
B. Inguinal epidermophytia
C. Pytiriasis versicolor
D. Candidiasis
E. Rubrophytia

2. What methods are used to diagnose Pytiriasis versicolor?


A. Microscopic examination
B. Luminescent method using a Wood lamp
C. Balzer test with iodine tincture
D. Benier's symptom method (chip phenomenon)
E. All answers are correct
3. What elements of the rash are characteristic of Pytiriasis versicolor?
A. Papule
B. Macule
C. Nodule
D. Vesicle
E. Pustule

4. What pathogen Pytiriasis versicolor?


A. Trich. mentagrophytes
B. Microsporum canis
C. Pityrosporum orbiculare
D. Pityrosporum ovale
E. Candida albicans
F. Trich. rubrum

5. Concomitant diseases that are most common in children with


candidiasis are:
A. Chronic recurrent acute respiratory viral infections, bronchitis,
pneumonia
B. Purulent otitis and chronic tonsillitis
C. Atopic dermatitis
D. Asthmoid bronchitis
E. Everything is listed

6. What pathogen causes infiltrative-suppurative trichophytia


(kerion)?
A. Trich. violaceum
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

7. What pathogen causes anthropophilic microsporia?


A. Trich. mentagrophytes
B. Microsporum ferrugineum
C. Pityrosporum orbiculare
D. Candida albicans
E. Trich. rubrum
8. Indicate the most important clinical sign of microsporia of the scalp.
A. Scales
B. Hyperemia
C. Focal nature of the lesion
D. Broken hairs
E. Crusts

9. In the treatment of microsporia of the scalp griseofulvin prescribed


in a dose of:
A. 22 mg per day
B. 22 mg three times a day
C. 22 mg per kg of body weight three times a day
D. 22 mg per kg of body weight per day
E. 2 mg per reception

10. What pathogen causes epidermophytia of the feet?


A. Trich. mentagrophytes var. interdigital
B. Microsporum canis
C. Pityrosporum orbiculare
D. Trich.verrucosum
E. Trich. rubrum

Standards of answers: 1 - C. 2 E. 3 B. 4 C. 5 E. 6 D. 7 B. 8
D. 9 D. 10

1. With what diseases most often have to differentiate the


microspores of the scalp? A. Pityriasis versicolor
B. Lichen ruber planus
C. Pityriasis rosea
D. Alopecia areata

2. What are the clinical symptoms characteristic of


infiltrativesuppurative trichophytia of the scalp?
A. Intoxication
B. Lymphadenitis
C. Rising body temperature
D. Hair loss in the lesion
E. All answers are correct

3. What methods of laboratory diagnosis should be carried out in


trichomycoses: A. Histological
B. Microscopic
C. Bacteriological

4. What is used for laboratory diagnosis of trichomycoses:


A. Blood
B. Nails, hair, scales
C. Cerebrospinal fluid
D. The content of the sebaceous glands

5. What clinical varieties belong to the mycosis of the feet caused by


Trich. mentagrophytes var. interdigetale
A. Intertriginous
B. Onychomycosis
C. Dyshydrotic
D. Squamous-hyperkeratotic
E. All answers are correct

6. For which disease is the pathognomonic symptom "Honeycombs"?


A. Microsporia
B. Infiltrative-suppurative trichophytia
C. Pityriasis versicolor
D. Candidiasis
E. Rubrophytia

7. What drugs are used to treat dermatophytes?


A. Griseofulvin
B. Oxolinic ointment
C. Tetracycline
D. Nystatin
E. Prednisolone

8. Specify a diagnostic test that confirms the diagnosis of microsporia


of the scalp:
A. Scraping is a symptom of "blood dew"
B. In smears - acantholytic cells.
C. Detection of mycelium in scales.
D. The appearance of blisters in the application test with 50%
potassium iodide ointment. E. Brock's rehearsal.

9. What diagnostic test can be performed to diagnose " Pityriasis


versicolor ": A. Diascopy. B. The Auspices trial.
B. Balzer's test.
G. Yadason's test.
D. Thompson's test.

10. Choose a drug that is used to treat tinea pedis: A.


Flucinar.
B. Sulfur ointment 20%.
B. Mycoseptin.
G. Sinaflan.
D. Elocom.
Standards of answers: 1-D. 2-E. 3-B. 4-B. 5-E. 6-B. 7- -C. 9-C. 10-C

1. Characteristic feature of simple contact dermatitis is:


A. Fuzzy boundaries of the lesion
B. Clear boundaries of the lesion
C. Occurrence only in sensitized patients
D. Occurrence in 12-74 hour after exposure to a certain factor
E. Possible generalization of the process

2. It is not observed in allergic contact dermatitis: A. Rash on the place


of influence of a certain factor
B. Clear boundaries of the lesion
C. Occurrence in sensitized patients
D. Subacute onset and course
E. Possible recurrence after re-exposure to the allergen

3. Which of the following is not used for the treatment of allergic


contact dermatitis:
A. Glucocorticoids containing creams and ointments
B. Antihistamines
C. Hyposensitizing drugs
D. Vitamins
E. Photosensitizers

4. Toxicodermatosis is not characterized by:


A. Acute onset
B. Symmetry of rash
C. Polymorphic rash
D. Development of lichenification
E. Possible lesion of mucous membranes

5. Fixed erythema is not characterized by:


A. Occurrence as a result of taking sulfonamides, antibiotics etc.
B. Occurrence due to exposure to obligate irritants
C. Rash of several red spots 2-5 cm in diameter
D. Localization on the skin, genital and oral mucosa
E. After recourse pigmentation remains for a long time

6. Which of the following is not applied for the treatment of


toxicodermatosis:
A. Enterosorbents
B. Photosensitizers
C. Antihistamine drug
D. Detoxification drugs
E. Glucocorticoid creams

7. Lyell's syndrome is characterized by:


A. Isomorphic Koebner response
B. Auspitz triad
C. Nikolsky's symptom
D. Meshcherskiy-Besnier's symptom
E. Jadassohn's symptom
8. Which of the following form is not characteristic for eczema:
A. Idiopathic
B. Microbial
C. Herpetiformal
D. Occupational
E. Seborrheal

9. Which of the following does not belong to the main diagnostic


criteria for assessment of the severity of atopic dermatitis:
A. Skin itch
B. Ichthyosis, mostly of palms
C. Typical morphology and localization of skin rashes: in infants
are eczematous rash on the face and extensor surfaces of the
extremities, in older children and adults - lichenification on
flexor surfaces of thextremities
D. Chronic relapsing course
E. Atopy in personal and family history

10. Primary morphological element with urticaria is considered:


A. Vesicle B. Bulla
C. Macule
D. Blister
E. Knot

Standards of answers: 1 B, 2 B, 3 -D, 5 B, 6 C, 8 C, 9 B, 10


D.

1. What is the recommended topical treatment in seborrheic


dermatitis like psoriasis of the face and ear canals?
A. Photochemotherapy
B. Reflexotherapy
C. Acyclovir
D. Mineral oil
E. Clobetasol propionate
2. Everything mentioned below is specific to allergic contact
dermatitis, except:
A. Sensibilization
B. Margination of lesions spreads in the periphery beyond the
actual site of exposure
C. ACD is due to reexposure to a substance to which the
individual is sensitized D. Margins of lesions are
sharp
E. Polymorphism of skin eruption

3. Histopathology in acute irritant contact dermatitis:


A. Epidermal cell necrosis, neutrophils, vesiculation, and
necrosis
B. Acanthosis, hyperkeratosis, lymphocytic infiltrate
C. Spongiosis, lymphocytes and eosinophils in the epidermis,
and monocyte and histiocyte infiltration in the dermis
D. Spongiosis plus acantosis, elongation of rete ridges, and
elongation and broadening of papillae; hyperkeratosis; and a
lymphocytic infiltrate

4. The most common form of occupational skin diseases is:


A. Irritant contact dermatitis
B. Allergic contact dermatitis
C. Atopic dermatitis
D. Nummular eczema
E. Toxidermia

5. Which are the clinical symptoms of mycotic eczema?


A. The presence of pustules
B. Vesiculation
C. Increasing of lymph nodes
D. No correct answer

6. The plumber came to the doctor complaining of redness, burning


sensation, pain in the right forearm. Some rash appeared in 10-
15 minutes after contact with hot pipes. Objectively: on the skin
of the right forearm extensor surface there is a severe focus with
clear boundaries of 3x6 cm; there is skin hyperemia in the focus,
some individual bullous elements with clear content. Make a
diagnosis:
A. Dermatitis herpetiformis Duhring
B. Allergic contact dermatitis
C. Eczema
D. Simple contact dermatitis
E. Pemphigus vulgaris

7. 32-years old female patient consulted the dermatologist


complaining of some rash on the skin of neck and chest,
accompanied by itching. Rash appeared after taking aspirin and
kept on the skin for about two hours and then without any action
gradually disappeared appearing at new areas. Objectively,
there are multiple palm-sized urticaria elements. The patient has
red dermographism; eosinophilia is revealed in the blood. What
kind of skin disease can be thought of in this case:
A. Urticaria
B. Allergic dermatitis
C. Eczema
D. Simple contact dermatitis
E. Atopic dermatitis

8. A boy of 7 years complains of feeling unwell, pain on swallowing,


painful rashes on the lips and in the mouth, itchy rash on the face
and body, which appeared three days after receiving Analgin
because of acute otitis. Objectively: the general state of the child
is severe; body temperature is 38.6 °C. On the skin of the lips and
oral mucosa, there are common erosions with massive
hemorrhagic crusts. On the face and body multiple
erythematous spots and edematous papules with deep bluish
center, on the surface of which there are vesicles and blisters;
the elements tend to be drained. Nickolsky's sign is negative.
What kind of emergency prehospital care should be provided to
the child:
A. To prescribe corticosteroids orally, canceling all other drugs B.
To prescribe corticosteroids parenterally, canceling all other
drugs
C. To prescribe corticosteroid ointments, canceling all other
drugs
D. To prescribe antihistamine drugs, canceling all other drugs
E. To prescribe purgatives, canceling all other drugs
9. Female patient, 37 years old, employed as a manipulative nurse,
complains of feeling unwell, weakness, headache, muscle and
joint pain and skin rash, accompanied by severe pain and
burning sensation. Some rash appeared two days after receiving
ampicillin because of sore throat. Objectively: general condition
of the patient is severe; body temperature is 39.2 °C. The entire
skin is bloodshot. On the trunk and extremities, there are
multiple bullous elements, erosion, fragments of epidermis
observed. The skin is painful on palpation. Nikolsky's sign is
positive. What kind of emergency prehospital care should not be
provided to the child:
A. Stop taking ampicillin
B. To prescribe corticosteroids parenterally
C. To prescribe enterosorbents
D. To refer the patient to the intensive care unit for further
treatment
E. To refer the patient for consultation and supervision of the
allergist

10. 34 years old woman consulted the dermatologist about the skin
lesions of hands and lower third of the forearm as a significant
swelling, redness, vesiculation. Got ill one week ago. The disease
appeared after use of 'Lotus' washing powder. In the past, the
patient has no skin diseases. What is the most likely diagnosis in
this patient:
A. Contact allergic dermatitis
B. Simple contact dermatitis
C. Dyshidrotic eczema
D. Toxicodermatosis
E. Microbial eczema

Standards of answers: 1 E, 2 D, 3 B, 4 B, 5 B, 6 D, 7 A, 8
B, 9 A, 10 A
1. What are the main pathohistological changes in pemphigus vulgaris?
A. Spongiosis
B. Acanthosis

C. Acantholysis
D. Hyperkeratosis
E. Parakeratosis

2. The most important laboratory tests to confirm the diagnosis of


pemphigus vulgaris are:
A. Sowing the contents of the blister on the flora
B. Clinical blood test
C. Blood tests for electrolytes
D. Investigation of smears-imprints on acantholytic cells
E. Investigation of blister contents for eosinophil s

3. Indicate the most important diagnostic symptom to confirm the


diagnosis of pemphigus: A. The Kebner phenomenon
B. Nikolsky's symptom
C. Balzer's test
D. Mantoux reaction
E. Isomorphic reaction

4. The most characteristic morphological elements for Duhring's


herpetiform dermatosis are:
A. Erythematous macules
B. Papules
C. Bullae
D. Vesicles
E. All of the above is true

5. In which layer of the skin are the blisters in the case of pemphigus
vulgaris? A. Papillary
B. Basal
C. Spinosum
D. Granular
E. Corneum
6. Acantholytic cells by the method of Tzank detected by the study:
A. Histological
1. Acantholytic cells by the method of Tzank found in:
A. Native culture
B. Histological preparation
C. Smear-imprint
D. Blood tests
E. Serological examination.

2. In the case of localization of rashes with pemphigus vulgaris on the


oral mucosa, histopathological changes (acantholysis) occur in:
A. The granular layer
B. Spiny layer
C. Basal layer
D. Actually the mucous plate
E. Submucosal layer

3. The most typical localization of rashes in pemphigus vulgaris:


A. The scalp
B. Face
C. The mucous membrane of the oral cavity
D. Elbows and knees
E. Palms and soles

4. To confirm the diagnosis of Duhring's herpetiform dermatitis it is


necessary to conduct a skin test to determine hypersensitivity to:
A. Sulfanilamides
B. Antibiotics
C. Novocaine
D. Iodides
E. Bromide
5. What are the characteristics of Duhring's herpetiform dermatitis?
A. Recurrent course
B. Monomorphism of rashes
C. No itching
D. Positive symptom of Nikolsky
E. Frequent lesions of the mucous membranes

6. Bullae in the case of Duhring's dermatitis are placed:


A. Subcorneally
B. Intraepidermal
C. Subepidermal
D. Subdermally
E. Subhypodermal

7. At what bullous dermatosis at patients hypersensitivity to gluten is


quite often observed? A. Pemphigus vulgaris
B. Exfoliative pemphigus
C. Duhring's dermatitis
D. Stevens-Johnson syndrome
E. Seborrheic pemphigus

8. With Duhring's dermatosis, patients complain of:


A. Pain
B. Itching
C. Feeling of cold extremities
D. The feeling of crawling "ants" on the body
E. Paresthesia

9. Specify the most effective drug for the treatment of pemphigus:


A. Penicillin
B. Sulfadimethoxine
C. Ftivazid
D. Prednisolone
E. Delagil

10. For the treatment of Duhring's herpetiform dermatitis most often


used: A. Antibiotics B. Vitamins
C. Antihistamines
D. Preparations of the sulfone series (DDS)
E. Antimalarial drugs

Standards of answers: 1-C. 2-B. 3-C. 4-D. 5- -C. 7-C. 8-B. 9-D. 10-D

1. For which disease is the pathognomonic iodine test of Balzer?

A. Microsporia

B. Inguinal epidermophytia
C. Pytiriasis versicolor

D. Candidiasis

E. Rubrophytia

2. What methods are used to diagnose Pytiriasis versicolor?

A. Microscopic examination

B. Luminescent method using a Wood lamp

C. Balzer test with iodine tincture

D.

E. All answers are correct

3. What elements of the rash are characteristic of Pytiriasis


versicolor? A. Papule

B. Macule

C. Nodule

D. Vesicle

E. Pustule
4. What pathogen Pytiriasis versicolor?

A. Trich. Mentagrophytes

B. Microsporum canis

C. Pityrosporum orbiculare

D. Pityrosporum ovale

E. Candida albicans

F. Trich. Rubrum

5. Concomitant diseases that are most common in children with


candidiasis are:

A. Chronic recurrent acute respiratory viral infections,


bronchitis, pneumonia

B. Purulent otitis and chronic tonsillitis

C. Atopic dermatitis

D. Asthmoid bronchitis

E. Everything is listed

6. What pathogen causes infiltrative-suppurative trichophytia


(kerion)?

A. Trich. Violaceum
B. Microsporum canis

C. Pityrosporum orbiculare

D. Trich.verrucosum

E. Trich. Rubrum

7. What pathogen causes anthropophilic microsporia?

A. Trich. Mentagrophytes

B. Microsporum ferrugineum

C. Pityrosporum orbiculare

D. Candida albicans

E. Trich. Rubrum

8. Indicate the most important clinical sign of microsporia of the


scalp. A. Scales

C. Hyperemia

D. Focal nature of the lesion

E. Broken hairs

F. Crusts
9. In the treatment of microsporia of the scalp griseofulvin
prescribed in a dose of:

A. 22 mg per day

B. 22 mg three times a day

C. 22 mg per kg of body weight three times a day

D. 22 mg per kg of body weight per day

E. 2 mg per reception

10. What pathogen causes epidermophytia of the feet?

A. Trich. Mentagrophytes var. interdigital

B. Microsporum canis

C. Pityrosporum orbiculare

D. Trich.verrucosum

E. Trich. Rubrum

Standards of answers: 1 C. 2 E. 3 B. 4 C. 5 E. 6 D. 7 B. 8

E. 9 D. 10
1. With what diseases most often have to differentiate the
microspores of the scalp?

A. Pityriasis versicolor

B. Lichen ruber planus

C. Pityriasis rosea

D. Alopecia areata

2. What are the clinical symptoms characteristic of


infiltrativesuppurative trichophytia of the scalp?

A. Intoxication

B. Lymphadenitis

C. Rising body temperature

D. Hair loss in the lesion

E. All answers are correct


3. What methods of laboratory diagnosis should be carried out in
trichomycoses: A. Histological

C. Microscopic

D. Bacteriological

4. What is used for laboratory diagnosis of trichomycoses:

A. Blood

B. Nails, hair, scales

C. Cerebrospinal fluid

D. The content of the sebaceous glands

5. What clinical varieties belong to the mycosis of the feet caused


by

Trich. Mentagrophytes var. interdigetale

A. Intertriginous

B. Onychomycosis

C. Dyshydrotic

D. Squamous-hyperkeratotic
E. All answers are correct

6. For which disease is the pathognomonic symptom

A. Microsporia

B. Infiltrative-suppurative trichophytia

C. Pityriasis versicolor

D. Candidiasis

E. Rubrophytia

7. What drugs are used to treat dermatophytes?

A. Griseofulvin

B. Oxolinic ointment

C. Tetracycline

D. Nystatin

E. Prednisolone

8. Specify a diagnostic test that confirms the diagnosis of


microsporia of the scalp:

A.
B. In smears acantholytic cells.

C. Detection of mycelium in scales.

D. The appearance of blisters in the application test with 50%

9.

C. The Auspices trial.

C.

F.

D.

10. Choose a drug that is used to treat tinea pedis: A. Flucinar.

B. Sulfur ointment 20%.

B. Mycoseptin.

G. Sinaflan. D. Elocom.

Standards of answers: 1-D. 2-E. 3-B. 4-B. 5-E. 6-B. 7- -C. 9-C. 10-C
1. Characteristic feature of simple contact dermatitis is:

A. Fuzzy boundaries of the lesion

B. Clear boundaries of the lesion

C. Occurrence only in sensitized patients

D. Occurrence in 12-74 hour after exposure to a certain factor

E. Possible generalization of the process

2. It is not observed in allergic contact dermatitis: A. Rash on the place


of influence of a certain factor

B. Clear boundaries of the lesion


D. Occurrence in sensitized patients

E. Subacute onset and course

F. Possible recurrence after re-exposure to the allergen

3. Which of the following is not used for the treatment of allergic


contact dermatitis:

A. Glucocorticoids containing creams and ointments

B. Antihistamines

C. Hyposensitizing drugs

D. Vitamins

E. Photosensitizers

4. Toxicodermatosis is not characterized by:

A. Acute onset

B. Symmetry of rash

C. Polymorphic rash

D. Development of lichenification

E. Possible lesion of mucous membranes


5. Fixed erythema is not characterized by:

A. Occurrence as a result of taking sulfonamides, antibiotics etc.

B. Occurrence due to exposure to obligate irritants

C. Rash of several red spots 2-5 cm in diameter

D. Localization on the skin, genital and oral mucosa

E. After recourse pigmentation remains for a long time

6. Which of the following is not applied for the treatment of


toxicodermatosis:

A. Enterosorbents

B. Photosensitizers

C. Antihistamine drug

D. Detoxification drugs

E. Glucocorticoid creams

7.

A. Isomorphic Koebner response

B. Auspitz triad
C.

D. Meshcherskiy-

E.

8. Which of the following form is not characteristic for eczema:

A. Idiopathic

B. Microbial

C. Herpetiformal

D. Occupational

E. Seborrheal

9. Which of the following does not belong to the main diagnostic

Criteria for assessment of the severity of atopic dermatitis:

A. Skin itch

B. Ichthyosis, mostly of palms

C. Typical morphology and localization of skin rashes: in infants


are eczematous rash on the face and extensor surfaces of the
extremities, in older children and adults lichenification on
flexor surfaces of thextremities

D. Chronic relapsing course


E. Atopy in personal and family history

10. Primary morphological element with urticaria is considered:

A. Vesicle B. Bulla

B. Macule

C. Blister

D. Knot

Standards of answers: 1 B, 2 B, 3 -D, 5 B, 6 C, 8 C, 9 B, 10


D.

1. What is the recommended topical treatment in seborrheic


dermatitis like psoriasis of the face and ear canals?

A. Photochemotherapy

B. Reflexotherapy

C. Acyclovir

D. Mineral oil
E. Clobetasol propionate

2. Everything mentioned below is specific to allergic contact


dermatitis, except:

A. Sensibilization

B. Margination of lesions spreads in the periphery beyond the


actual site of exposure

C. ACD is due to reexposure to a substance to which the

Individual is sensitized D. Margins of lesions are sharp

D. Polymorphism of skin eruption

3. Histopathology in acute irritant contact dermatitis:

A. Epidermal cell necrosis, neutrophils, vesiculation, and


necrosis

B. Acanthosis, hyperkeratosis, lymphocytic infiltrate

C. Spongiosis, lymphocytes and eosinophils in the epidermis,


and monocyte and histiocyte infiltration in the dermis

D. Spongiosis plus acantosis, elongation of rete ridges, and


elongation and broadening of papillae; hyperkeratosis; and a
lymphocytic infiltrate

4. The most common form of occupational skin diseases is:

A. Irritant contact dermatitis


B. Allergic contact dermatitis

C. Atopic dermatitis

D. Nummular eczema

E. Toxidermia

5. Which are the clinical symptoms of mycotic eczema?

A. The presence of pustules

B. Vesiculation

C. Increasing of lymph nodes

D. No correct answer

6. The plumber came to the doctor complaining of redness, burning


sensation, pain in the right forearm. Some rash appeared in 10-15
minutes after contact with hot pipes. Objectively: on the skin of the
right forearm extensor surface there is a severe focus with clear
boundaries of 3x6 cm; there is skin hyperemia in the focus, some
individual bullous elements with clear content. Make a diagnosis:

A. Dermatitis herpetiformis Duhring

B. Allergic contact dermatitis

C. Eczema

D. Simple contact dermatitis


E. Pemphigus vulgaris

7. 32-years old female patient consulted the dermatologist


complaining of some rash on the skin of neck and chest,
accompanied by itching. Rash appeared after taking aspirin and
kept on the skin for about two hours and then without any action
gradually disappeared appearing at new areas. Objectively, there
are multiple palm-sized urticaria elements. The patient has red
dermographism; eosinophilia is revealed in the blood. What kind of
skin disease can be thought of in this case:

A. Urticaria

B. Allergic dermatitis

C. Eczema

D. Simple contact dermatitis

E. Atopic dermatitis

8. A boy of 7 years complains of feeling unwell, pain on swallowing,


painful rashes on the lips and in the mouth, itchy rash on the face
and body, which appeared three days after receiving Analgin
because of acute otitis. Objectively: the general state of the child is
severe; body temperature is 38.6 °C. On the skin of the lips and oral
mucosa, there are common erosions with massive hemorrhagic
crusts. On the face and body multiple erythematous spots and
edematous papules with deep bluish center, on the surface of which
there are vesicles and blisters; the elements tend to be drained.

care should be provided to the child:


A. To prescribe corticosteroids orally, canceling all other drugs
B. To prescribe corticosteroids parenterally, canceling all
other drugs

B. To prescribe corticosteroid ointments, canceling all other


drugs

C. To prescribe antihistamine drugs, canceling all other drugs

D. To prescribe purgatives, canceling all other drugs

9. Female patient, 37 years old, employed as a manipulative nurse,


complains of feeling unwell, weakness, headache, muscle and joint
pain and skin rash, accompanied by severe pain and burning
sensation. Some rash appeared two days after receiving ampicillin
because of sore throat. Objectively: general condition of the patient
is severe; body temperature is 39.2 °C. The entire skin is bloodshot.
On the trunk and extremities, there are multiple bullous elements,
erosion, fragments of epidermis observed. The skin is painful on

prehospital care should not be provided to the child:

A. Stop taking ampicillin

B. To prescribe corticosteroids parenterally

C. To prescribe enterosorbents

D. To refer the patient to the intensive care unit for further


treatment

E. To refer the patient for consultation and supervision of the


allergist
10. 34 years old woman consulted the dermatologist about the skin
lesions of hands and lower third of the forearm as a significant
swelling, redness, vesiculation. Got ill one week ago. The disease

patient has no skin diseases. What is the most likely diagnosis in


this patient:

A. Contact allergic dermatitis

B. Simple contact dermatitis

C. Dyshidrotic eczema

D. Toxicodermatosis

E. Microbial eczema

Standards of answers: 1 E, 2 D, 3 B, 4 B, 5 B, 6 D, 7 A, 8 B,
9 A, 10 A.
1. The main parameters for the differential diagnosis of psoriasis are:

A. The primary morphological element of the rash

B. Form of rash

C. The nature and location of peeling

D. Subjective feelings

E. All answers are correct

2. Name the main pathohistological changes in psoriasis:

A. Granulosis;

B. Hyperkeratosis, parakeratosis, acanthosis

C. Parakeratosis, acanthosis

D. Acanthosis

E. Polymorphic-cellular infiltration.

3. Clinical forms of psoriasis include:

A. Limited psoriasis
B. Psoriatic arthropathy

C. Sclero-atrophic psoriasis

D. Common psoriasis

4. Seasonal forms of psoriasis are:

A. Winter

B. Mixed

C. Early

D. Congenital

E. Autumn

5. List the clinical variants of lichen ruber planus:

A. Annular form

B. Erosive-ulcerative

C. Hypertrophic form

D. Bullous form

E. Atrophic form
F. All answers are correct

6. Characteristic of the stationary stage of psoriasis are:

A. The presence of new papular rashes

B. The presence of a tendency to peripheral growth

C.

D. Positive symptom of Koebner

E. Erythroderma

7. With what diseases it is necessary to carry out differential diagnosis


at suspicion of existence at the patient of a lichen ruber planus?

A. Psoriasis

B. Dermatomycosis

C. Diffuse neurodermatitis

D. Toxicoderma

E. Papulonecrotic tuberculosis

8. What are the symptoms of psoriatic rash?

A. The form of papules is miliary


B. Inflammatory papules

C. Non-inflammatory papules

D. The outlines of papules are polygonal

9. Lichen ruber planus is characterized by:

A. No itching

B. Itchy skin only at night

C. The appearance of rashes only on the extensor surfaces of the


extremities

D.

E. Bright pink rash

10. What physiotherapy procedures are used in the treatment of


psoriasis:

A. UVI (ultraviolet irradiation)

B. Balneotherapy

C. PUVA therapy

D. UHF therapy (ultra-high frequency)

E. All answers are correct


Standards of answers: 1 F. 2 B. 3 B. 4 F. 6 C. 7

B. 9 D. 10 E.

1. Choose the diagnostic phenomena characteristic of psoriasis:

A. The Kebner phenomenon

B. Symptom of stearin stain

C. Symptom of the terminal film

D. Symptom of Auschpitz

E. All answers are correct

2. Choose a symptom pathognomonic for LRP:

A.

B. Benier-
C.

D. Symptom Gorchakov-Ardi

E.

3. For the local treatment of psoriasis use:

A. Lorinden ointment A

B. 2% salicylic ointment

C. 3% naphthalene ointment

D. Dermovate

E. All answers are correct

4. For the stationary stage of psoriasis is characterized by:

A. The elements are completely covered with silvery-white


scales

B. On the periphery of the papules


rim)

C. The appearance of new rashes

D. Peripheral growth of elements

E. Pale pink color of rash elements


5. For the regressive stage of psoriasis is characterized by:

A. Around the elements

B. Disappearance of rashes

C. Pale color of the rash elements

D. Disappearance of scales from the surface of psoriatic rashes

E. All answers are correct

6. What are the most typical localization of rashes in the psoriatic


process?

A. Flexion surface of the extremities

B. Extensor surface of the extremities

C. Interdigital spaces

D. Skin around physiological openings

E. Genital mucosa

7. What symptom is not used to confirm the diagnosis of psoriasis?

A. Psoriatic triad

B. The Kebner phenomenon


C. Symptom of Auspices

D.

E.

8. What clinical sign is not characteristic of the progressive stage


of psoriasis?

A. Tendency to merge

B. The presence of a psoriatic triad

C. Silvery-white peeling in the center of the papule

D. The Kebner phenomenon

E. Silvery-white peeling over the entire surface of the papule

9. What is characteristic of psoriatic papules?

A. Yellow-red color

B. Umbilical indentation in the center of the papule

C. Oval shape

D. The surface is covered with white scales

E. Shiny surface
10. Clinical varieties of psoriasis do not include:

A. Seborrheic

B. Leaf-like

C. Exudative

D. Vulgar

E. Rupee

Standards of answers: 1-E. 2-C. 3-E. 4- -E. 6-B. 7-E. 8-E. 9-D. 10-B
1. What are the main pathohistological changes in pemphigus vulgaris?
A. Spongiosis

B. Acanthosis

D. Acantholysis

E. Hyperkeratosis

F. Parakeratosis

2. The most important laboratory tests to confirm the diagnosis of


pemphigus vulgaris are:

A. Sowing the contents of the blister on the flora

B. Clinical blood test

C. Blood tests for electrolytes


D. Investigation of smears-imprints on acantholytic cells

E. Investigation of blister contents for eosinophils

3. Indicate the most important diagnostic symptom to confirm the


diagnosis of pemphigus: A. The Kebner phenomenon

B.

D.

E. Mantoux reaction

F. Isomorphic reaction

4.
herpetiform dermatosis are:

A. Erythematous macules

B. Papules

C. Bullae

D. Vesicles

E. All of the above is true

5. In which layer of the skin are the blisters in the case of pemphigus
vulgaris? A. Papillary
B. Basal

D. Spinosum

E. Granular

F. Corneum

6. Acantholytic cells by the method of Tzank detected by the study:


A. Histological

11. In the study of Tzank material is stained by the method:

A. Gram

B. Tiel-Nielsen

C. Romanovsky-Gimse

D. Burry

E. Morozov

Standards of answers:: 1 C. 2 D. 3 B. 4 E. 5 C. 6 C. 7
B. 10 C.
1. Acantholytic cells by the method of Tzank found in:

A. Native culture

B. Histological preparation

C. Smear-imprint

D. Blood tests

E. Serological examination.

2. In the case of localization of rashes with pemphigus vulgaris on the


oral mucosa, histopathological changes (acantholysis) occur in:

A. The granular layer

B. Spiny layer

C. Basal layer

D. Actually the mucous plate

E. Submucosal layer

3. The most typical localization of rashes in pemphigus vulgaris:

A. The scalp

B. Face
C. The mucous membrane of the oral cavity

D. Elbows and knees

E. Palms and soles

4. dermatitis it is
necessary to conduct a skin test to determine hypersensitivity to:

A. Sulfanilamides

B. Antibiotics

C. Novocaine

D. Iodides

E. Bromide

5.

A. Recurrent course

B. Monomorphism of rashes

C. No itching

D. Positive symptom of Nikolsky

E. Frequent lesions of the mucous membranes

6.
A. Subcorneally
B. Intraepidermal

C. Subepidermal

D. Subdermally

E. Subhypodermal

7. At what bullous dermatosis at patients hypersensitivity to gluten is


quite often observed? A. Pemphigus vulgaris

B. Exfoliative pemphigus

C.

D. Stevens-Johnson syndrome

E. Seborrheic pemphigus

7. dermatosis, patients complain of:

A. Pain

B. Itching

C. Feeling of cold extremities

D.

E. Paresthesia
8. Specify the most effective drug for the treatment of pemphigus:

A. Penicillin

B. Sulfadimethoxine

C. Ftivazid

D. Prednisolone

E. Delagil

9.
used: A. Antibiotics

B. Vitamins

D. Antihistamines

E. Preparations of the sulfone series (DDS)

F. Antimalarial drugs

Standards of answers: 1-C. 2-B. 3-C. 4-D. 5- -C. 7-C. 8-B. 9-D. 10-D
1. Average duration of treatment of multibacillary leprosy?

A. 1 year

B. 2 year

C. 3 year

D. Life long

2. The most effective drug against M.leprae is ?

A. Dapsone

B. Rifampicin

C. Clofazimine

D. Prothionamide

3. Multidrug therapy is given for?

A. Syphilis

B. Leprosy
C. Herpetiformis

D. Icthyosis vulgaris

4. All lesions are seen in leprosy except?

A. Erythematous macule

B. Hypopigmented patch

C. Vesicles

D. Flat and raised patches

5. Which pathogen causes leprosy? A. Mycobacterium tuberculosis

B. Mycobacterium leprae

C. Mycobacterium bovis E. Mycobacterium

africanum

6. Which is other name of leprosy?

A.

B. disease

C.
7. Lepromin test help in? A. In the diagnosis of leprosy

B. In prognosis and classification of leprosy

C. In prognosis

8. The first sensation to be lost in leprosy is?

A. Temperature

B. Pain

C. Both at the same time

D. None

9. In leprosy nerves commonly involved are?

A. High ulnar, low median

B. High median, low ulnar

C. Triple nerve palsy

D. High radial, low median

10. Skin biopsy in leprosy is characterised by?

A. Periappendegial bacilli
B. Periappendegeal lymphocytosis

C. Perivascular lymphocytosis

D. All of the above

Standards of answers: 1 A, 2 B, 3 B, 4- B, 6 B, 8 A, 10
D.

1. An 8-year old boy from Bihar presents with a 6 month history of an


ill defined hypopigmented slightly atrophic macule on the face.

What is the most likely diagnosis?


A. Ptyriasis alba

B. Indeterminate leprosy

C. Morphacea

D. Calcium deficiency

2. The following drug is not used for the treatment of type II lepra
reaction (ENL)?
A. Chloroquine

B. Thalidomide

C. Cyclosporine

D. Corticosteroids

3. The main cytokine involved in ENL (Erythema Nodosum


Leprosum) reaction is?

A. Il-2

B. Ifn-Gamma

C. Tnf-Alpha

D. Mcsf

4. The following test is not used for diagnosis of leprosy?

A. Lepromin test

B. Slit skin smear

C. Fnac

D. Skin biopsy
5. A 27 year old patient was diagnosed to have borderline leprosy and
started on Multibacillary multi-drug therapy. Six weeks later, he
developed pain in the nerves and redness and swelling of the skin
lesions. The management of his illness should include all of the
following except?

A. Stop anti-leprosy drugs

B. Systemic corticosteroids

C. Rest to the limbs affected

D. Analgesics

6. Antileprotic drug also used in lepra reaction is ?

A. Rifampicin
B. Dapsone

C. Ciprofloxacin

D. Clofazimine

7. Best method of treatment of ulnar nerve abscess in case of leprosy


is?

A. High doses of steroid

B. Incision and drainage

C. Thalidomide

D. High dose of clofazimine


8. Inverted saucer shaped lesion is found in ?

A. Lepromatous leprosy

B. Tuberculoid leprosy

C. Borderline leprosy

D. Indeterminate leprosy

9. Lepromin test is positive in which leprosy?

A. Lepromatous

B. Indeterminate

C. Histoid

D. Tuberculoid

10. A 16 year old student reported for the evaluation of multiple


hypopigmented macules on the trunk and limbs. All of the following
tests are useful in making a diagnosis of leprosy except?

A. Sensation testing

B. Lepromin test

C. Slit smears
D. Skin biopsy

Standards of answers: 1- B, 2 C, 3 C, 4 A, 5 A, 6 D, 7 B, 8 C,

9 D,

10 B

1. What agent causes syphilis?

A. Pediculus corporis

B. Sarcoptes scabiei varietas hominis

C. Demodexfolliculorum

D. Treponema pallidum

E. Staph ilococcus albus

2. Which one of these diseases refers to classic veneral diseases?

A. Genital warts

B. Chancroid
C. Scabies

D. Pediculosis

E. All the above mentioned

3. The complications of hard chancre include:


A. Mortifying

B. Chancre-amygdalitis

C. Large chancre

D. Chancre-felon

E. Indurative edema

4. Name the atypical forms of primary syphiloma:

A. Balanitis, balanoposthitis

B. Phimosis

C. Indurative edema

D. Chancre-amygdalitis

E. All the above mentioned is true

5. Venereal syphilis in the human host is caused by: A. Treponema


pallidum ssp. Endemicum.
B. Treponema pallidum ssp. Pallidum (T. pallidum)

C. Treponema pallidum ssp. Pertenue

E. Treponema carateum

6. The most contagious stage of the syphilis is:

A. Primary syphilis

B. Secondary syphilis

C. Tertiary syphilis

D. Early latent syphilis

E. Late latent syphilis

7. Incubation period of primary syphilis is usually about:

A. 1-2 hours

B. 1-2 days

C. 1 week

D. 3 weeks

E. 5-6 months

8. Skin lesion in primary syphilis is:


A. Macule

B. Nodule

C. Vesicle

D. Ulcer

E. Wheal

9. Chancre-amygdalitis (specific amygdalitis) is not characterized:

A. The increase and induration of the amygdala without the


formation of erosion and ulcer

B. Absence of pain when swallowing

C. Unilateral affection, the absence of violations of the general


state of the body

D. Unilateral affection of submandibular and cervical lymph


nodes

E. Morbidity and bilateral affection

10. Primary period of syphilis lasts for:

A. 7-8 weeks

B. 14 weeks

C. 3-4 weeks
D. 3-4 months
E. 6 months

Standards of answers: 1 D, 2 E, 3 -D, 5 B, 6 A, 7 D, 8 D, 9

C.

1. A 32-year-old man presents with a 4-day history of painless penile


lesions. His sex partners are men and he has had 2 partners in the
last 6 months. Physical examination reveals 3 non-tender ulcers on
the lateral aspect of the penile shaft and firm lymphadenopathy in
the right inguinal region that is nontender. Oral examination and
skin inspection are normal. He has no neurologic symptoms. A
clinical diagnosis of syphilis is strongly suspected; nontreponemal
and treponemal serologic tests for syphilis are ordered. Based on
the information at this point, how would you clinically stage syphilis
in this man?

A. Primary syphilis

B. Secondary syphilis

C. Early latent syphilis

D. Late latent syphilis

2. The duration of latency in Latent syphilis is defined by:

A. An information received from a patient

B. A previous negative STS


C. 1 year

D. A previous negative STS 6 months

E. A previous negative STS 1 year

3. Everything A 25-years old female patient complains of swelling of


the right large pudental lip and discomfort. The general condition

data: swelling of the right large pudental lip. It is thick, nonsensitive


on palpation, with a dark-red and clear borders. The righthand
lymphadenitis is present too. Wassermann reaction is negative.
What is a possible diagnosis?

A. Limited elephantiasis

B. Unilateral bartholinitis

C. Indurative edema

D.

E. Cold abscess

4. Patient of the dermato-venereological department with a diagnosis

38.2 °C, malaise, headache, and the maculopapular rash on skin


appeared. How can these symptoms be explained?

A. As allergic reaction
B. As toxic reaction

C. As idiosyncratic reaction

D. As infectious disease

E. As viral disease

5. A 32 years old woman complaining of neck pathology turned to the


otolaryngologist. During examination: unilateral increase of the left
amygdala, which caused no pain when touching to it with a spatula.
The patient can not connect this kind of pathology with anything.

Which is the most probable disease:

A. Bartholinitis

B. Seropositive primary syphilis, chancre-amygdalitis

C. Seronegative primary syphilis, typical hard chancre

D. Seropositive primary syphilis, indurative edema

E. Catarrhal angina

6. A 45-year-old man is screened for syphilis and has a positive


Treponema pallidum-specific enzyme-linked immunoassay (EIA).
The laboratory performs a reflexive Rapid Plasmin Reagin (RPR)
test that is nonreactive. Tests for HIV, Neisseria gonorrhoeae, and
Chlamydia trachomatis are negative. He has no medical problems,
takes no medications, and does not use illicit drugs. He has been
sexually active with the same female partner for the past 3 years.
He has no prior history of any sexually transmitted infections, and
has never been tested or treated for syphilis. He is asymptomatic
and the physical examination is normal.

A. What is most appropriate next step in the management of this


man?

B. Repeat both the EIA and the RPR

C. Send an alternative nontreponemal test

D. Send an alternative treponemal test

E. Further work-up at this time

7. A 29-year-old woman is seen in an STD clinic with vaginal discharge


and is diagnosed and treated for chlamydia. Laboratory studies sent
at that time show a positive treponemal enzyme immunoassay
(EIA) and a positive Venereal Disease Research Laboratory (VDRL)
test at a titer of 1:16. She has had four male sex partners in past 3
years. She had a negative syphilis VDRL test 5 years ago when she
was pregnant, but has not had any additional syphilis testing until
now. She has never been treated for syphilis and has no past or
current signs or symptoms consistent with syphilis. Her physical
examination is normal and a pregnancy test is negative. She does
not have any antibiotic allergies. What is the best therapy for this
woman?

A. No treatment is necessary

B. Benzathine penicillin G 2.4 million units intramuscularly in a single


dose

C. Benzathine penicillin G 7.2 million units total, administered as

2 doses of 2.4 million units IM each at 1-week intervals 3


D. Ceftriaxone 1 g daily either IM for 10 days
8.. A 42-year-old man is diagnosed with primary syphilis based on a
non-painful genital ulcer and positive syphilis serologic tests. He
reports one new male and one female sex partner in the past 90
days. Both partners are contacted and instructed to come to the
clinic for evaluation. The female partner reports sexual contact with
the 42year-old man about 3 weeks ago. She has no symptoms and
says she had negative testing for bacterial sexually transmitted
infections (STIs) and HIV about 6 months ago. She does not have
any antibiotic allergies. What would you recommend for this
woman specifically related to management of her as a syphilis
contact?

A. She does not need further evaluation or treatment at this time since
she is asymptomatic

B. Order serologic tests for syphilis and treat only if the syphilis test is
positive

C. Order serologic tests for syphilis and treat with intramuscular


benzathine penicillin G 2.4 million units in a single dose before
results return

D. Because the exposure occurred 3 weeks ago, defer serologic testing


for syphilis for 3 more weeks and treat only if the syphilis test is
positive

9) . A boy A 31-year-old man with HIV who is on antiretroviral therapy


with a CD4 count of 370 cells/mm3 and an HIV RNA level less than
40 copies/mL presents with a painless ulcer in his perirectal area.
He was last tested for sexually transmitted diseases, including
Neisseria gonorrhea, Chlamydia trachomatis, and syphilis 12 weeks
ago and all test results were negative. His repeat laboratory results
on the most recent visit have returned with a positive rectal
gonorrhea nucleic amplification test, a positive treponemal enzyme
immunoassay (EIA), and a positive Rapid Plasmin Reagin (RPR) test
with a titer of 1:128. He has never been previously diagnosed with
or treated for syphilis. He has no neurologic or ocular symptoms.
Treatment for rectal gonorrhea is ordered. What is the
recommended treatment of syphilis in this man with HIV?

A. Amoxicillin 500 mg orally three times a day for 7 days

B. Azithromycin 2 grams orally once

C. Benzathine penicillin G 2.4 million units intramuscular in a single


dose

D. Benzathine penicillin G 7.2 million units total, administered as 3


doses of 2.4 million units intramuscular each at 1-week intervals

10) 25-year-old man presents for evaluation of new nontender penile lesion. He
has no other symptoms. He has no medical problems, denies medications or
illicit drugs and has no antibiotic allergies. He reports insertive-only anal
intercourse with multiple male partners and rare condom use. Physical
examination reveals a 1 cm, nontender ulcer on the dorsal surface of his
penis and no other significant findings. Further testing reveals a positive
syphilis enzyme immunoassay (EIA) and a positive Rapid Plasma Reagin (RPR)
at a titer of 1:32. He has never been diagnosed with or treated for syphilis in
the past. An HIV test returns negative.

A. What is the appropriate therapy for this man?

B. Amoxicillin 500 mg orally three times a day for 7 days

C. Azithromycin 2 grams orally once

D. Benzathine penicillin G 2.4 million units intramuscular in a single


dose

E. Benzathine penicillin G 7.2 million units total, administered as 3


doses of 2.4 million units intramuscular each at 1-week intervals
Standards of answers: 1 A, 2 B, 3 C, 4 B, 5 B, 6 D, 7 C, 8 C,
9 C, 10 D.

1. A specific lesion of secondary syphilis is:

A. Chancres

B. Syphilids

C. Gumma

D. Syphilitic granuloma

E. Ulcers

2. A 22-year-old female patient, single, complains of skin rash on


the trunk and extremities without subjective sensations.
Objective data: the general condition of the patient is

pink symmetrical spots up to 1 cm in diameter without a


tendency to consolidation on the skin of the trunk, upper and
lower extremities. Genital organ examination: a round ulcer
with firm borders, painless, in the stage of epithelization is
found on the skin of the right vulvar lip; moderate
polyadenitis. There is an enlarged (to 1,5 cm) painless and
movable on palpation lymph node in the right inguinal region.
What is the provisional diagnosis for this patient?

A. Epidermoid cancer

B. Primary syphilis

C. Soft chancre

D. Chancriform pyoderma

E. Secondary syphilis

3. A 25-year-old female patient, single, complains of hoarseness,


which appeared without any causes. The patient does not

which healed in 5 weeks without any treatment. Objective


data: the general condition of the patient is satisfactory, the

diameter) pale pink spots, which disappear when one presses


with a slide on the lateral surfaces of the trunk. On the left
vulvar lip there is a fresh scar (of round shape, 0.7 cm in
diameter). An examination of the pharynx showed that the
tonsil mucosa is red with a copper tint. The focus has clear
borders without purulent incrustation. There is a moderate
polyadenitis. What is the provisional diagnosis of this
patient?

A. Epidermoid cancer

B. Secondary syphilis

C. Soft chancre
D. Chancriform pyoderma

E. Erythema nodosum

4. A patient is a 21-year-old pregnant woman. Her syphilis tests


are strong positive. Objective data: condylomata lata in the
perineum region, single grouped maculopapular spots of the
upper trunk, syphilitic leukoderma of the neck. The viscera
and neurologic system are not affected. What stage of syphilis
is observed in this patient?

A. Secondary recurrent syphilis

B. Latent syphilis

C. Primary seropositive syphilis

D. Tertiary syphilis

E. Early secondary syphilis

5. From 2000-2020, what has been the trend in the overall


annual number of cases of syphilis?

A. Increased

B. Decreased

C. Stayed about the same

D. Increased for first 5 years, then steadily decreased


6. A 19-year-old woman presents for a new maculopapular rash
on her trunk, which includes the palms of her hands and soles
of her feet. She has no other medical problems, takes no
medications, and denies illicit drug use. She has never been
tested for sexually transmitted infections (STIs) before. She
has had three male partners in the past 6 months with
intermittent condom use. One of her male partners also has
sex with men. A clinical diagnosis of secondary syphilis is
make and laboratory testing is ordered to confirm the
diagnosis of syphilis. Which one of the following is TRUE
regarding the laboratory diagnosis of syphilis in this woman?

A. Approximately 50% of persons with secondary syphilis have a


negative B. Treponema pallidum enzyme immunoassay (EIA) C. The
degree of elevation in the enzyme immunoassay (EIA) titer can
accurately distinguish primary from secondary syphilis D. A
reactive treponemal test does not require any further confirmatory
testing

F. A reactive nontreponemal test should be confirmed by a treponemal


test

7. In the case of syphilitic lesion of placenta the significant alterations


are observed:

A. In maternal placenta

B. In fetal placenta

C. The significant alterations are not observed

D. All mentioned above is correct

E. All mentioned above is false


8. Which of the following does not refer to the probable signs of the
late congenital syphilis:

A. The shortcut little finger

B. Parenchymatous keratitis

C. The absence of xiphoid process


D.

9. A 69-year-old male patient complains of an ulcer of the penis.


Objective data: a round ulcer with clear margins and a smooth
bottom is on the skin of the glans penis. It has a freshly color with
grayyellowish bloom in the center. The skin around the ulcer is
without any changes. One can palpate swollen lymph nodes in the
right inguinal region, they are painless and movable. There are a lot
of small pink spots on the upper trunk, which do not bother the
patient. What is a possible diagnosis?

A. Secondary syphilis

B. Primary syphilis

C. Epithelioma spinocellulare

D. Chancriform pyoderma

E. Scabies

10. A 30-year-old male patient complains of head and eyebrow hair


loss that begun 2 weeks ago without any cause. The patient has no
somatic pathologies. Objective data: multiple small foci of hair loss
and round foci of sparse hair on the back of the head and temporal
areas. The skin n these foci is without any changes. There are some
lenticular thickened copper-colored papules on the skin of the
upper trunk without any inflammatory changes around them. What
is your preliminary diagnosis?

A. Alopecia areata

B. Seborrheic alopecia

C. Secondary syphilis

D. Trichophytosis capitis

E. Lichen ruber planus

Standards of answers: 1 B, 2 E, 3 B, 4-A, 5 A, 6 D, 7 B, 8 B, 9 A, 10

B.

1.) 30-year-old man presents for follow-up of a positive syphilis serologic


test result. Recent laboratory studies from a routine visit 10 days ago
show a positive treponemal enzyme immunoassay (EIA) and a positive
Rapid Plasma Reagin (RPR) with a titer of 1:256. He had a negative HIV-
1/2 antigen-antibody test and is taking tenofovir DFemtricitabine for
HIV preexposure prophylaxis (PrEP). He has routine STD testing every 3
months. His serologic tests for syphilis have always been negative. He
denies any genital ulcers or skin manifestation. Upon further inquiry, he
reports he has had blurry vision in the right eye over the past 4 days.
Which one of the following is a correct statement about the
manifestations of ocular syphilis?

A. All persons with ocular syphilis have neurosyphilis


B. Uveitis is the most common manifestation of ocular syphilis
C. Corneal lesions are the most common manifestation of
ocular syphilis

C. Retinal necrosis is the most common manifestation of ocular


syphilis

2.) patient is a 40-year-old man. Blood investigation: Wasserman reaction


and TPI test are positive. There are no changes of the skin, viscera or
neurologic system. What is a probable diagnosis of this patient?

3.) Latent recurrent syphilis

4.) Primary seropositive syphilis

5.) Secondary recurrent syphilis

6.) Tertiary syphilis

7.) Early latent syphilis

3) 42-year-old male patient complains of skin rash without any subjective sensations.
Objective data: multiple pink spots up to 0.30.7 cm in size on the skin of the upper
trunk and extremities; the surface of the spots is not desquamated. Besides, they are
separated. Polyadenitis is observed. There is an erosion at the stage of epithelization
on the prepuce. What is a possible diagnosis?

A. elization

B. Secondary latent syphilis

C. Typhoid fever

D. Medicamentous toxicoderma (drug eruption)


E. Secondary recurrent syphilis

4) mass health examination in an orphanage discovered a boy with deviations in the


physical and mental development. Objective
lesions, the lymph nodes are not enlarged; the boy has a brachicephalic skull, a
saddle-shaped
preliminary diagnosis?

a. Late latent syphilis

b. Early congenital syphilis

c. Latent congenital syphilis

d. Tertiary syphilis

e. Late congenital syphilis

5) A 31-year-old male presents to his primary care medical


provider for evaluation of a rash. He denies taking any new
medications, but reports three new male sexual partners in the
last 8 weeks. The rash began several days prior as an
erythematous, maculopapular rash on the chest and back and
now it also involves the palms and soles. He does not have any
ocular or neurologic symptoms. Serologic testing for syphilis is
ordered. What is the most appropriate treatment of this patient
with presumed secondary syphilis?

a. Azithromycin 2 grams orally once

b. Doxycycline 100 mg orally twice daily x 28 days


c. Benzathine penicillin G 2.4 million units intramuscular in
a single dose

d. Benzathine penicillin G 7.2 million units total,


administered as 3 doses of 2.4 million units given at 1-
week intervals

6) A 47-year-old man is clinically diagnosed with secondary


syphilis and treated with benzathine penicillin G 2.4 million
units intramuscular (IM) in a single dose. Their lab test results
return with a positive syphilis enzyme immunoassay (EIA) and
a positive Rapid Plasma Reagin (RPR) at a titer of 1:128. Their
HIV test is negative. Follow-up RPR testing at 6 months shows
an RPR titer of
1:4.

a. What would you recommend as the next course of action


regarding management of syphilis for this individual?

b. Treat with a single dose of intramuscular benzathine


penicillin G 2.4 million units

c. Treat with benzathine penicillin G 7.2 million units total,


administered as 3 intramuscular doses of 2.4 million units
given at 1-week intervals

d. Perform a lumbar puncture and cerebrospinal fluid


analysis and treat based on these findings

e. No further treatment is necessary at this time and lumbar


puncture is not indicated

7) A 24-year-old man presents with a 3-day history of a diffuse


rash. He reports having 7 sex partners, within the last 3 months.
Physical examination shows an erythematous macular rash on
his chest, back, arms, and palms. He has no visual or neurologic
complaints and a neurologic examination is normal. A clinical
diagnosis of secondary syphilis is made. Laboratory studies are
ordered and he is treated with a single intramuscular dose of 2.4
million units of benzathine penicillin G. Subsequently, the
baseline laboratory studies show a positive treponemal enzyme
immunoassay (EIA), a Rapid Plasma Reagin (RPR) titer of 1:512,
and a negative HIV1/2 antigen-antibody test.

a. When should repeat syphilis serologic evaluation be


performed?

b. No follow-up is needed since he received recommended


therapy

c. 6 and 12 weeks

d. 6 and 12 months

e. 12 and 24 months

8) A 25-year-old man is diagnosed with secondary syphilis based


on a diffuse maculopapular rash and a Rapid Plasma Reagin
(RPR) titer of 1:256. He is given an intramuscular dose of 2.4
million units of benzathine penicillin G in the clinic, but
approximately 4 hours after receiving the dose of penicillin, he
returned with complaints of fever, headache, myalgia, dizziness,
and intensification of his rash. Physical examination shows a
temperature of 38.5°C, blood pressure 96/74 mmHg,
accentuation of the rash, but no evidence of hives,
oropharyngeal swelling, or wheezing.

a.
symptoms?

b. Mild type IV anaphylactic reaction to penicillin


c. Allergic reaction to benzathine

d. Prozone reaction

e. Jarisch-Herxheimer reaction

9) A 43-year-old man with a positive Rapid Plasma Reagin (RPR)


test (titer of 1:64) is referred for further evaluation and
treatment of syphilis. He reports having a total body rash and
low-grade fever that resolved about 3 months prior. He reports
severe headaches in the past week with nausea, vomiting, and
mild photophobia. The headache has not resolved with over-the-
counter medications and he has no history of headaches. He has
not had prior testing or treatment for syphilis. A recent HIV
antigen-antibody test is negative. A lumbar puncture is
performed, with cerebrospinal fluid analysis, to evaluate for
neurosyphilis. Which one of the following statements is TRUE
regarding cerebrospinal fluid (CSF) laboratory studies in
diagnosing neurosyphilis?

a. The CSF Venereal Diseases Research Laboratory (VDRL)


test is highly specific; it is the preferred test for confirming
a suspected diagnosis of neurosyphilis

b. The CSF Rapid Plasma Reagin (RPR) test is the most


sensitive and specific test for diagnosing neurosyphilis; it
is the preferred test both for confirming and excluding
neurosyphilis

c. The CSF fluorescent treponemal antibody absorbed


(FTAABS) test has poor sensitivity and no role in
diagnosing neurosyphilis

d. There is no role for CSF treponemal or nontreponemal


tests in diagnosing neurosyphilis
10) A 22-year-old woman is diagnosed with neurosyphilis
after presenting with stroke-like symptoms and a positive
treponemal enzyme immunoassay (EIA) and a positive Rapid
Plasma Reagin (RPR) test (titer of 1:128). A lumbar puncture is
performed with cerebrospinal fluid analysis that shows protein
of 64 mg/dL, white blood cell count of 18 (80% lymphocytes), a
red blood cell count of 0, and a positive Venereal Disease
Research Laboratory (VDRL) titer of 1:64. Tests for other causes
of stroke, as well as an HIV test are negative. She has a 2-year
history of engaging in transactional sex, but has never previously
been tested or treated for syphilis. She denies any history of
allergic reactions to antibiotics. What is the most appropriate
antimicrobial therapy for treatment of neurosyphilis in this
woman?

a. Ceftriaxone 1 g intramuscular once daily for 5 days,


followed by doxycycline 100 mg orally twice daily for 14
days

b. Ceftriaxone 1 g intramuscular once daily for 10 to 14 days

c. Benzathine penicillin G 7.2 million units total,


administered as 3 doses of 2.4 million units intramuscular
each at 1-week intervals

d. Aqueous crystalline penicillin G 18 to 24 million units per


day, administered as 3 to 4 million units intravenous every
4 hours (or continuous infusion), for 10 to 14 days

Standards of answers: 1 A, 2 C, 3 E, 4 E, 5 C, 6 E, 7 D, 8 E,
9 A, 10 D.

1. The pathogen of gonorrhea is:


A. Trichomonas vaginalis

B. Treponema pallidum

C. Chlamydia

D. Candida albicans

E. Gonococcus

2. Genital candidosis is not predisposed by:

A. A history of allergy

B. Hormonal contraception

C. Pregnancy

D. Diabetes mellitus

E. HIV-infection

3. A 26-year-old female patient has appealed to a gynecologist


with complaints of primary sterility. The patient has chronic
adnexitis. A microscopic investigation of the cervical canal
scrape showed a microorganism Chlamydia. What
medicines would you prescribe for etiotropic treatment?

A. Penicillin

B. Trichopol
C. Azithromycin

D. Sulfadimethoxine

E. Nystatin

4. A 20-year-old male patient complains of profuse discharge


from the urethra, urination is painful in the beginning. He
connects this disease with a sexual contact, which took place
4 days before. Objective data: profuse purulent discharge
from the urethra, which is s
positive (nebulous urine in the first glass). There are
diplococcic in the smears. What is a possible diagnosis?

A. Total gonorrheal urethritis

B. Posterior gonorrheal urethritis

C. Anterior gonorrheal urethritis

D. Latent gonorrhea

E. Gonorrheal urethro-prostatitis

5. Which pathogen causes gonorrhea?

A. Staphylococcus aureus

B. Pelobacter acidigallici

C. Lachnospira multiparus

D. Neisseria gonorrhea
E. Trichomonas vaginalis

6. What is the average incubation period in case of gonorrhea


infection?

A. 24 hours

B. 3-10 days

C. 2-4 weeks

D. 2 months

E. 1 month

7.

A. Chlamydia trachomatis

B. Trichomonas

C. Gram-positive diplococcus

D. Gram-negative diplococcus

E. Gardnerella vaginal
8. What method of staining is used for microscopic diagnosis of
gonorrhea?

A.

B. May-Grunwald-Giemsa stain

C.

D. Romanovsky-Giemsa stain

E. Hematoxylin and eosin stain

9. Specify the possible variants of the course of gonococcal


urethritis in men:

A. Recent acute gonorrheal urethritis

B. Recent subacute gonorrheal urethritis

C. Chronic gonorrheal urethritis

D. Asymptomatic gonorrheal urethritis

E. All the above

10. Which sign is typical for the clinic of acute anterior


gonorrheal urethritis in men?

A. There is no discharge

B. Discharge is insignificant
C. Discharge is purulent in large amount

D. Appearance of drops of blood at the end of urination

E. Pain at the end of urination

Standards of answers: 1 - D, 6

1. A 24-year-old man presents to the clinic requesting testing for


sexually transmitted infections (STIs). He has a new female partner and
he is interested in making sure he does not have any STIs. Currently, he
has no genitourinary symptoms. Which one of the following diagnostic
tests is the most sensitive for the detection of urethral Neisseria
gonorrhoeae infection in an asymptomatic male?
A. Nucleic acid amplification test (NAAT)
B.
C. Culture
D. Methylene blue-gentian violet stain microscopy

2. A 33-year-old man with one sexual partner develops urethral


discharge and is diagnosed with gonorrhea; he is treated with
recommended therapy. His symptoms resolved after treatment, but he
returns 10 days later with recurrent purulent urethral discharge and a
he urethral discharge shows multiple
gram-negative diplococci.
symptoms?
A. Defer any additional therapy until a definitive etiology is
determined
B. Retreat with the same regimen because
reinfection is more likely than treatment
failure
C. Consider the patient a treatment failure
and empirically treat for cephalosporin-
resistant Neisseria gonorrhoeae
D. Consider the patient a treatment failure
due to coinfection with another pathogen
and empirically treat for urethral
trichomoniasis

3. Histopathology A 32-year-old woman presents to her primary


care medical provider's office with abnormal vaginal discharge. She is
diagnosed with cervical chlamydia and treated with appropriate
therapy. She notifies her sex partner about her diagnosis of chlamydial
infection so that he can come in for testing and treatment. She is not
pregnant and following treatment she is asymptomatic. Which one of
the following is the recommended regarding follow-up chlamydia
testing for a woman treated for uncomplicated cervical chlamydia who
does not have persistent or recurrent symptoms?
A. Perform a test-of-cure nucleic acid amplification test (NAAT)
10 days after treatment completion
B. Perform a test-of-cure nucleic acid amplification test (NAAT)
3 weeks after treatment completion
C. Send a cervical specimen for culture and sensitivity testing
within 2 weeks of the positive nucleic acid amplification test
(NAAT) result
D. Retest 3 months after completion of therapy

4. A 29-year-old woman returns to the health department for


treatment after receiving a positive test result for chlamydia. Her
sexual partner attends the visit with her, and both are treated for
chlamydial infection. Assuming both the patient and her sex partner
have received appropriate therapy for Chlamydia trachomatis and all
symptoms have resolved, what instruction should they receive
regarding resuming their sexual activities?
A. Abstain from sexual activity until 48 hours after completing
therapy
B. Abstain from sexual activity until 72 hours after completing
therapy
C. Abstain from sexual activity until 7 days
after completing therapy
D. Abstain from sexual activity until 14
days after completing therapy

5. To treat genitourinary trichomoniasis they use:


A. Metronidazolum, Ornidazole
B. Metacyclinum, Doxycyclinum
C. Medrol, Itraconazolum
D. Macropen, Erythromycinum
E. Benzylpenicillin,Amoksiklav
6. A 25-year-old female patient complains of profuse smelly
discharge from the vagina, burning and itching in the genitals. She has
been suffering for a week. The woman has a couple of sexual partners.
Objective data: hyperemic mucosa of the genitals, bleeding on palpation
and profuse foamy white discharge from the vagina. What is a possible
diagnosis?
A. Chlamidiosis
B. Gonorrhea
C. Trichomonas colpitis
D. Candidomycosis of the vagina
E. Bacterial vaginosis

7. A patient is 25 years old, single, have multiple sexual partners. In


the last three months noticed slight mucoserous discharge from urethra;
subjectively - intermittent itching or burning sensation in the ureter.
Two months ago there was a pain in the knee joint. At the same time the
patient neither got hurt, nor supercooled. A week ago, he felt discomfort
in he eyes - watery eyes, itching. Which probable pathogen has caused
the disease?
A. Trichomonas vaginalis
B. Chlamydia trachomatis
C. Candida
D. Gardnerella vaginalis
E Neisseria gonorrhoeae

8. A 24 years old patient appealed to family medicine clinic with


complaints of pain in the knee joints, fever up to 37, 7 C, pain during
urination and a feeling of sand in the eyes. The patient has been sick for
the past 6 weeks. Has no regular sexual partner. Objectively: the affected
joints are swollen; movements are painful and somewhat limited. Feet
hyperkeratosis. Blood test: WBC - 9.3 x 109 /1, ESR - 32 mm / hour.
Rheumatoid factor test is not available. What kind of infection is possible
in this case?
A. Trichomonas
B. Chlamydia
C Candida
D. Gonococcal
E Staphylococcal

9. Female A pregnant woman with a pregnancy of 20 weeks


consulted obstetriciangynecologist. At examination she was diagnosed
with gonorrhea. What should be the medical tactics in this case:
A. Treatment with antibiotics in the third
trimester of pregnancy
B. Treatment with antibiotics after
delivery
C. Urgent treatment with sulfanilamidums
D. Urgent treatment with benzylpenicillin
E. Urgent treatment with tetracycline

10. 34 The patient addressed to venereologist with complaints about


painful urination, abundant purulent discharge from the urogenital
organs. She considers herself to be ill during a week. She associates the
disease with the casual sexual contact about 3-4 weeks ago. The
preliminary diagnosis of acute gonorrhea of the lower genital tract is
confirmed. At the bacterioscopic research of discharge they will detect:
A. Proteus vulgaris
B. Mycoplasma
C. Trichomonads
D. Gram-negative diplococci
E. Gram-positive diplococci

Standards of answers: 1 A, 2 B, 3 D, 4 C,
5 A, 6 C, 7 B, 8- B, 9 A,
10 D.

1. HIV is a:
Arbovirus
Papillomavirus
Retrovirus
Herpes virus
Adenovirus

2. AIDS is a condition caused by:


A. Yeast
B. Candida albicans
C. Proteus vulgaris
D. Bacteria
E. HIV infection

2. AIDS does not declare itself as:


Infectious skin lesions
Allergic dermatitis
Seborrheic dermatitis
Hairy (cobblestone) tongue
Tumors
3. Which medicines are recommended for the treatment of AIDS patients?
Antiviral
Sedatives
Antimalarial
Antihistamines
Analgesics

5. Place of differentiation of T-lymphocytes:


A. Thymus
B. Bone marrow
B. Lymph node
D. Blood serum

6. Nucleic acid of HIV:


A. DNA
B. RNA and DNA
B. RNA

7. Is it possible to reproduce HIV in T-suppressors?


A. No
B. Yes, provided there is an intercurrent infection
B. Yes
D. Sometimes possible

8. Is HIV damage to T-killers?


A. Yes
B. No
C. Yes, but with hyperinfection by other viruses
D. Sometimes it is possible

9. Is it possible to damage CNS cells with human immunodeficiency


virus?
A. No
B. Probably, but on condition that the patient has any of the infections
B. Yes
G. Sometimes it is possible

10. HIV is classified:


A. HIV-1
B. HIV-1 and HIV-2
C. HIV-1 and HIV-2 and HIV-3
Standards of answers: 1 C, 2 E, 3 B, 4-A, 5 A, 6 B, 9 B, 10
B.

1. What are the clinical features of herpes simplex in AIDS patients?


A. Localization: the oral mucosa, genitals
B. Localization: the extremities
C. Sharp pain
D. Erosion formation
E. Frequent recidives

2.
by:
A. Localization: the lower extremities
B. Localization: the face, oral mucosa
C. Young age of patients
D. Damages of the internal organs
E. Lymphoadenopathy

3. A 28-year-old male patient was hospitalized with diarrhea (3-4


times a day), weight loss, rapid fatigability, breathing problems, cough.
A clinical examination of this patient showed pneumocystic
pneumonia. The patient has had multiple sexual contacts with stranger
women. What disease can be suspected in this case?
A. Nonspecific ulcerative colitis
B. Tuberculous mesenteric lymphadenitis
C. Dysenteric diarrhea
D. AIDS
E. Tertiary syphilis

4. A patient complains of moderately painful rash on the surface of


the tongue. He has been suffering for the last 2 months. The patient has
had multiple sexual contacts with stranger women. Objective data:
gray-white plaque on the lateral surface of the tongue. It is covered
with thin hair-like processes. What is a preliminary for this patient?
A. Pemphigus vulgaris
B. Candidiasis of the tongue
C. Herpes simplex
D. AIDS: cobblestone tongue
E. Secondary syphilis
5. Which are the skin symptoms of microbial AIDS?
A. Diffuse alopecia
B. Seborrhoeic eczema
C. Skin infections
D. All are correct
E. No correct answer

6. Which medicines are recommended for the treatment of AIDS


patients?
A. Abacavir
B. Acyclovir

D. Loratadine
E. Valacyclovir

7. 32-years old female patient with HIV consulted the


dermatologist complaining of some rash on the scalp and chest,
accompanied by itching. What kind of skin disease can be thought of in
this case:
A. Alopecia
B. VZV
C. Seborrhoeic eczema
D. Simple contact dermatitis
E. Atopic dermatitis

8. Which are the complications of AIDS patients?


A. Tuberculosis
B. Cytomegalovirus
C. Candidiasis
D. Cryptococcal meningitis
E. All are correct

9. Chronic HIV infection is characterized by:


A. Fever
B. Fatigue
C. Diarrhea
D. Weight loss
E. All are correct

10. A 29-year-old man is evaluated in an urgent care clinic with a 3-


day history of fever, fatigue, and lymphadenopathy. After an extensive
work-up, he is diagnosed with acute HIV infection; has an initial HIV
RNA level of 887,000 copies/mL. Additional baseline HIV laboratory
studies are ordered that include CD4 cell count and HIV genotypic drug
resistance testing. Which one of the following strategies is
recommended regarding the timing of initiating antiretroviral therapy
in this man who is diagnosed with acute HIV infection?
A. Promptly initiate antiretroviral therapy
B. Wait until the CD4 count decreases to less than 500 cells/mm3
C. Wait 12 weeks and reevaluate after determining whether
spontaneous clearance of HIV occurs
D. Wait 6 months for the viral set point to be established and this
will determine whether he needs antiretroviral therapy

Standards of answers: 1 E, 2 C, 3 D, 4 D, 5 D, 6 A, 7 C, 8 E, 9
E,
10 A.

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