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Genetics Notes - Other Patterns of Inheritance & Pedigrees
Genetics Notes - Other Patterns of Inheritance & Pedigrees
B. Codominance
1. Pattern of inheritance where both alleles in the heterozygous
offspring are FULLY expressed
2. Example: Human Blood Type
a. Genotype = Letters; Phenotype = Blood Type
b. Type A: AA, AO (homozygous & heterozygous)
c. Type B: BB, BO (homozygous & heterozygous)
d. Type AB: AB (ONLY heterozygous)
e. Type O: OO (ONLY homozygous)
3. Punnett Square Example:
a. Knowing that blood type shows a pattern of
codominance, cross a person with TYPE O blood and one
with TYPE AB blood.
Name:____________________________________________ Date:____________________
O O
Phenotype:
Type A = 50% A AO AO
Type B = 50%
Type AB = 0%
Type O = 0% BO BO
B
C. Sex-linked
1. Phenotypic expression of an allele that is dependent on the
gender of the individual
2. Carried on either sex chromosome (X or Y)
a. Remember: Female = XX; Male = XY
b. Many more genes carried on the X chromosome, so many
more X-linked traits than Y-linked traits
i. Examples: Hemophilia, Color-blindness
ii. FEMALES: If have only healthy X, it dominates over
the infected X.
iii. MALES: If have only one infected X, Y can’t
dominate over it.
3. Punnett Square Example
a. Knowing that COLOR BLINDNESS is a sex-linked trait, cross a
CARRIER FEMALE with a NON-INFECTED MALE.
b. Determine the probability of this couple having a color-
B= normal vision blind child. B
X Y
b = color blind
B B B B
X X X X Y
b
X XB X b b
X Y
D. Polygenic Traits
1. One trait is controlled by TWO or MORE genes
2. Example:
a. Human skin color
E. Multiple Alleles
1. More than two alleles for the same gene
Name:____________________________________________ Date:____________________
2. Example:
a. Human blood type (phenotypes produced by 3 different
alleles)
F. Pleiotropy
1. Single gene affects MORE than one trait
2. Examples:
a. Sickle cell disease
b. Marfan’s syndrome
II. Pedigree
A. Chart that shows how a trait and the genes that control it are passed
through a family
1. Most knowledge of human genetics comes from studying
patterns of heredity in populations and families
2. Best way to trace these patterns is by creating a pedigree
B. Symbols:
Symbol Description
Unaffected male
Unaffected female
Affected male
Affected female
Connected Symbols:
Mrs. Mr.
Pedigree Example: Mrs. Smith
Mr. Smith
I
Renaldo Renaldo
II
III
I Clarisse
Although Jane and Joe Smith have dimples, daughter, Clarisse does not. Joe’s dad
has dimples, but his mother and his sister, Grace, do not. Jane’s dad, Mr. Renaldo, her
brother, George, and her sister, Emily, do not have dimples but her mother does.