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Question Bank For Pharmacology I (As Per MG University Kerala)
Question Bank For Pharmacology I (As Per MG University Kerala)
Kerala)
GENERAL PHARMACOLOGY
1) Diff: routes of drug administration with egs of drugs given by that route and its adv & dis
adv?***
2) Explain the factors governing route on administration with examples?
3) Write a note on various receptors?
4) Various signaling mech: involved in drug action?***
5) Explain the importance of PPB and distribution?***
6) Factors influencing biotransformation of drugs?
7) Compare competitive and noncompetitive antagonism with suitable egs?***
8) Write a note on toxicity studies/preclinical studies***?(acute, sub acute, chronic, &
specialized toxicity studies)
9) Write a note on physiological barriers? ( BBB**, blood placental & blood testis barriers)
10) Explain microsomal enzyme system?**
11) Explain the phase I and phase II biotransformation reactions with egs?**
12) A note on enterohepatic cycling and its significance?**
13) A note on clinical trials?***
14) A note on factors governing passive diffusion of drugs?
15) Explain bio availability and factors affecting it?**
16) Theories of drug action / D-R interaction?*
17) Explain first pass metabolism and its significance?**
18) Briefly write on channels of excretion of drugs?
19) Write on genetic factors influencing drug action?
20) Explain plasma protein binding and add a note on its significance?***
21) Write a note on dose response relation ship?** ( DRC, LDR, EC50, LD50, therapeutic
index*, therapeutic window* etc)
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
22) Dose calculations for child dose?
23) Factors modifying drug action?
24) Combined drug action?**
25) A note on modified drug actions?
26) Write a detail note on second messengers?
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
EXPALIN THE MECHANISM OF ACTION OF THE FOLLOWING 2.5-3 marks
HAEMOPOIETIC SYSTEM
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
a) Oral anti coagulants*, haemetinics, parenteral iron therapy, various iron
preparation, coagulants,*
RESPIRATORY SYSTEM
1. Classify drugs for asthma and explain the pharmacology of any one drug?*
2. Explain the mechanism of action of the following?
a) Theophylline, zileuton, monteleukast*, loratidine, bromhexine
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
a, Osmotic diuretics*
b, Loop diuretics*
c, Potassium sparing diuretics*
d, anti diuretics
a, Classify anti diuretics with examples and explain the pharmacology of any one
drug?*
b, Mention the therapeutic indications and adverse effects of diuretics giving suitable
examples?
ANTI DIABETICS
2] Write briefly on
1. Insulin preparations*
2. Insulin analogues*
3. Insulin receptors
3] Long question
1) Classify oral anti diabetic drugs with examples and explain the pharmacology of
sulfonyl urea?*
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
Adrenergic nonselective beta blockers like propranolol should cautiously taken along
with insulin
2] Brief notes
Oxytocin*
Uterine relaxants/ tocolytics
2] Write a note on
1. Classify Anti thyroid drugs with examples and explain their uses and adverse effect?*
CORTICOSTEROIDS
GONADAL HORMONES
ORAL CIONTRACEPTIVES
1, Explain the mechanism of action of oral contraceptives?
2, Write a note on oral contraceptives/ hormonal contraceptives?*
Write briefly the main factors regulating calcium homeostasis? Their therapeutic uses?
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha
AUTOCOIDS
Write brief notes on
THERAPEUTIC GASES
Prepared by
Mr. Arun K Thomas
Sr. lecturer
Nirmala college of Pharmacy
Muvattupuzha