ENDOCRINE SYSTEM

Objectives:
At the end of the lesson, the students should be able to:

a. Compare control of body functions by the nervous system and endocrine

system.
b. Distinguish between exocrine and endocrine glands.
c. Compare the two chemical classes of hormones based on their solubility.
d. Know the maintenance of life
e. Learn how to maintain life.

As girls and boys enter puberty, they start to develop striking differences in
physical appearance and behavior. Perhaps no other period in life so
dramatically shows the impact of the endocrine system in directing
development and regulating body functions.

 In girls, estrogens promote accumulation of adipose tissue in the breasts

and hips, sculpting a feminine shape.
 At the same time or a little later, increasing levels of testosterone in boys
begin to help build muscle mass and enlarge the vocal cords, producing a
lower-pitched voice.

These changes are just a few examples of the powerful influence of endocrine
secretions. Less dramatically, perhaps, multitudes of hormones help maintain
homeostasis on a daily basis.
A. COMPARISON Of CONTROL BY THE NERVOUS AND ENDOCRINE
SYSTEM

Hormones regulate the activity of smooth muscle, cardiac muscle, and some
glands; alter metabolism; spur growth and development; influence
reproductive processes; and participate in circadian (daily) rhythms.

 The nervous system controls homeostasis through nerve impulses and

neurotransmitters, which act locally and quickly. The endocrine system uses
hormones, which act more slowly in distant parts of the body.
 The nervous system controls neurons, muscle cells, and glandular cells; the
endocrine system regulates virtually all body cells.

B. ENDOCRINE GLANDS

 Exocrine glands (sudoriferous, sebaceous, mucous, and digestive)

secrete their products through ducts into body cavities or onto body surfaces.
Endocrine glands secrete hormones into interstitial fluid. Then, the hormones
diffuse into the blood.
 The endocrine system consists of endocrine glands (pituitary, thyroid,
parathyroid, adrenal, and pineal glands) and other hormone-secreting tissues
(hypothalamus, thymus, pancreas, ovaries, testes, kidneys, stomach, liver,
small intestine, skin, heart, adipose tissue, and placenta).

Location of many endocrine glands. Also shown are other organs that
contain endocrine cells and associated structures. Endocrine glands secrete
hormones, which circulating blood delivers to target tissues.
C. HORMONE ACTIVITY

 Hormones affect only specific target cells that have receptors to recognize
(bind) a given hormone. The number of hormone receptors may decrease
(down-regulation) or increase (up-regulation).
 Circulating hormones enter the bloodstream; local hormones (paracrines
and autocrines) act locally on neighboring cells.
 Chemically, hormones are either lipid-soluble (steroids, thyroid hormones,
and nitric oxide) or watersoluble (amines; peptides, proteins, and
glycoproteins; and eicosanoids).
 Water-soluble hormone molecules circulate in the watery blood plasma in a
―free‖ form (not attached to plasma proteins); most lipid-soluble hormones
are bound to transport proteins synthesized by the liver.

D. CONTROL Of HORMONE SECRETION

 Hormone secretion is controlled by signals from the nervous system,

chemical changes in blood, and other hormones.

Negative feedback systems regulate the secretion of many hormones.

THYROID GLAND – produces a hormone that regulates the rate of

metabolism or the chemical
changes that take place in cells to produce energy

PITUITARY GLAND – the so-called ―master gland‖ that manufactures

several hormones of great
importance in physical growth and development.

GONADS – which are responsible for the bodily changes in boys and girls at
adolescence.

E. DEVELOPMENT OF ENDOCRINE SYSTEM

The development of the endocrine system is not as localized as in other

systems because endocrine organs develop in widely separated parts of the
embryo.

 The pituitary gland, adrenal medulla, and pineal gland develop from
ectoderm; the adrenal cortex develops from mesoderm; and the thyroid gland,
parathyroid glands, pancreas, and thymus develop from endoderm.
 MAINTENANCE OF THE BODY

MAINTENANCE OF LIFE

Life depends on the availability of the following:

A) WATER
B) FOOD
C) PRESSURE

HOMEOSTASIS - maintenance of a stable internal environment of the body.

All organisms must maintain a constant internal environment to function

properly:

• Temperature
• pH (acidic or basic)
• Salinity (salt level)
• Fluid levels

To Maintain Life, Human must perform the ff:

1) Digestion
2) Excretion
3) Growth
4) Maintenance of boundaries
5) Metabolism
6) Movement
7) Responsiveness
8) Reproduction
SUMMARY

Estrogens - promote accumulation of adipose tissue in the breasts and hips,

sculpting a feminine shape.

Increasing levels of testosterone in boys

begin to help build muscle mass and enlarge the vocal cords, producing a
lower-pitched voice.

Hormones - regulate the activity of smooth muscle, cardiac muscle, and

some glands; alter metabolism; spur growth and development; influence
reproductive processes; and participate in circadian (daily) rhythms.

Nervous system - controls homeostasis through nerve impulses and

neurotransmitters, which act locally and quickly.

Endocrine system - uses hormones, which act more slowly in distant parts of
the body.

Exocrine glands - (sudoriferous, sebaceous, mucous, and digestive) secrete

their products through ducts into body cavities or onto body surfaces.
Endocrine glands secrete hormones into interstitial fluid. Then, the hormones
diffuse into the blood.

Location of many endocrine glands. Also shown are other organs that
contain endocrine cells and associated structures.

Endocrine glands - secrete hormones, which circulating blood delivers to

target tissues.

Hormones - affect only specific target cells that have receptors to recognize
(bind) a given hormone. The number of hormone receptors may decrease
(down-regulation) or increase (up-regulation).

Hormones - are either lipid-soluble (steroids, thyroid hormones, and nitric

oxide) or watersoluble (amines; peptides, proteins, and glycoproteins; and
eicosanoids).

Water-soluble hormone molecules - circulate in the watery blood plasma in

a ―free‖ form (not attached to plasma proteins); most lipid-soluble hormones
are bound to transport proteins synthesized by the liver.

Hormone secretion - is controlled by signals from the nervous system,

chemical changes in blood, and other hormones.

Negative feedback systems - regulate the secretion of many hormones.

THYROID GLAND - produces a hormone that regulates the rate of
metabolism or the chemical changes that take place in cells to produce
energy.

PITUITARY GLAND - the so-called ―master gland‖ that manufactures

several hormones of great importance in physical growth and development.

GONADS - which are responsible for the bodily changes in boys and girls at
adolescence.

HOMEOSTASIS - maintenance of a stable internal environment of the body.

ACTIVITY 1. IDENTIFICATION (2 POINTS EACH)
Instruction: Give what is asked.
Rule: Wrong spelling wrong.

1. The _____________________ uses hormones, which act more slowly in

distant parts of the body.
2. The _____________________ controls homeostasis through nerve
impulses and neurotransmitters, which act locally and quickly.
Increasing levels of _____________________ in boys
begin to help build muscle mass and enlarge the vocal cords, producing a
3. lower-pitched voice.
4. _____________________ Also shown are other organs that contain
endocrine cells and associated structures.
5. _____________________ secrete hormones, which circulating blood
delivers to target tissues.
6. (FOR 5 POINTS) GIVE THE FULL NAME OF THE INSTRUCTOR UNDER
THIS SUBJECT.

ANSWER KEY

1. endocrine system
2. nervous system
3. testosterone
4. Location of many endocrine glands
5. Endocrine glands

6. SYLVESTER GUSTO (5 POINTS)

HONESTY IS THE BEST POLICY!

 REFLECTION

The endocrine system controls the growth development during

childhood, Regulation of the bodily functions in adulthood, and the
reproductive process. We the students realize that studying in such in the field
that we don’t know is Hard. Hand in hand, we realize That this subject will
help us to know The importance to the relative connection of the physical
education and anatomy itself. We have come up to the idea that life is A
Broad existence to the world. each of the following topics that we discussed is
all about how the endocrine system work and we discuss its importance.The
endocrine system is important for the control and regulation all the major
functions and processes of the body such as energy control and reproduction.

Life could not work without the help of the endocrine system because
right from the start of our childhood, it helps us to grow and develop ourselves
until such time. Endocrine system plays a big role in The reproduction of
humans so another systems will be created. Life is a full cycle with the help of
the endocrine system because this is one of the reason why ourselves or our
body is working Throughout our lives. As a human being, we are able to
realize that it is important to protect and maintain the health of the endocrine
system. as we discussed the maintenance of life, we tackled all of the needs
of our endocrine system. we realize to maintain not just endocrine system but
all of the systems that is responsible for our survival each and single day.
REFERENCES

Gulada, 2020. JMP-Anatomy-Physiology-Module

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