Swift River Medication Administration

Mechanism of Indications for What to monitor Major AEs/Blackbox Nursing

Name/Dose/Route/Frequency Action administration (VS/Labs/etc) warning considerations
 Inhibitor of  Assess for S/Sx of
HMG-CoA  S/sx Myopathy,  Increase HbA1c, myopathy, liver
 Atorvastatin(Lipitor)/30mg tab/ reductase  Hypercholesterolem Liver function test, Elevated blood function test, lipid
PO/QD inhibitor ia Lipid panel glucose panel
 CNS depression,
Respiratory
 Inhibition of S/sx of multiorgan depression ,
alpha 2 on sensitivity, Hypersensitivity  Drowsiness,
voltage gated Drowsiness, reactions, Suicidal Suicidality, ALOC,
 Gabapentin(Neurontin)/300mg calcium channels  Postherpetic Suicidality, ALOC, ideations or and respiratory
tab/PO/TID on the brain neuralgia, Seizures Resp depression tendencies depression
 Stimulates Monitor for signs
release of of hypoglycemia, If
pancreatic beta immediate give 30
cells which mins before meal,
increase insulin  Syncope, Dizziness, If extended give
 Glipizide(glucotrol)/10mg sensitivity at  Monitor for signs of Diarrhea, Tremors, with first meal of
tab/PO/QD peripheral sites  DM Type 2 hypoglycemia Increased BUN the day
 Blocks Na
reabsorption in  Check labs for
distal tubules electrolyte
which causes  Electrolyte abnormalities,
excretion of Na disturbances, Gout, assess BP before
and H2O, K+ and Monitor BP, Fluids Ocular glaucoma, admin and after,
 Hydrochlorothiazide(HCTZ)/ H+ will also  Edema, (I&O), Weight, Dermatologic Assess weight,
12.5mg cap/QD follow Hypertension Electrolytes Toxicity Fluid I&O
 ACE inhibitor
prevents the
conversion of  BUN, Cr., CBC w  AKI, Angioedema,
angiotensin I to HFrEF, Hypertension, diff, Liver function, Cough, BP, HR, Signs of
 Lisiniopril(Zestril)/10mg tab/BID angiotensin II ST elevation MI BP, HR Hyperkalemia angioedema
 Metformin(Glucophage)/  Decreases  DM Type 2  HbA1c, UA for  BBW: Lactic  Monitor for lab
 hepatic
production of
glucose, and
decrease
reabsorption of abnormalities,
glucose and acidosis hypoglycemia,
increases insulin ketones and GI effects, Vit B12 report signs of
1000mg tab/ BID sensitivity glucose, GFR, B12, deficiency acidosis
 Inhibits Instruct patient
histamine at H2 about signs and
receptors on the symptoms of a
gastric parietal gastric bleed, teach
cells inhibiting  B12 deficiency, about timing of
 Famotidine(pepcid)/ 20mg tab/ gastric acid CBC, Occult blood, Gastric malignancy, when to give the
BID secretion  GERD, Heartburn gastric pH renal impairment. medication
 Competes with  Vomiting,
histamine at H1 Headache,
receptors on GI Assess for signs of Drowsiness, Check renal labs
 Fexofenadine(Allegra)/ 180mg tract and Upper respiratory relief and assess dizziness, Diarrhea, and assess for signs
tab/ QD respiratory tract allergies renal function Nausea , dyspepsia of relief
 Inhibits HMC-
CoA reductase,
decreasing levels
of hsCRP reducing Hypercholesterolemi  Hepatic effects
inflammation a, Prevention of increased serum  Assess patient for
plaque, platelet atherosclerotic  Assess liver enzyme transaminases and abnormalities,
 Simvastatin(Zocor)/ 40mg ER and anticoagulant cardiovascular tests, Assess CPK, hepatotoxicity, assess for signs of
Tab/ QD effects disease Lipid panels Myopathy myopathy.
 Relaxes smooth
muscle by
activating of
guanylate cyclase
which increases  Headache,
cGMP causing dizziness, abnormal
smooth muscle heart sounds, A-fib,
relaxation. bradycardia,
 Isosorbide(imdur)/ 60mg ER Vasodilatation arrhythmias, Hypotension and GI
Tab/ QD effects.  Angina pectoris BP and HR cardiac failure upset
 Clopidogrel (Plavix)/ 75mg Tab/  It blocks STEMI, NSTEMI, MI, Monitor for signs of  Diminished Assess for lab
 irreversibly P2Y
component of
ADP receptors on abnormalities, s/s
platelet surface antiplatelet effects, of bleeding ,
preventing bleeding, educate patient
activation of Hypersensitivty about not
GPIIb receptors Ischemic stroke, reactions, and discontinuing
causing reduced Peripheral bleeding, monitor Thrombotic medication without
platelet atherosclerotic Hemoglobin and thrombocytopenic a physicians
QD aggregation disease hematocrit purpura oversight.
 Binds to target
tissues regulating
metabolism of Hypoglycemia,
carbs, fats, and teach patient about
proteins. HbA1C, electrolytes, assessing glucose
Stimulates renal function test, levels, needle use,
hepatic glycogen and liver function and drawing up
 Novolog/ PRN SubQ/ PRN synthesis. MD 1 and 2 tests  Hypoglycemia from the vials.
 Irreversibly
inhibits
cyclooxygenase 1
&2. Resulting in  Analgesic, Anti-  Baseline CBC, iron,
the inhibition of inflammatory, liver function test,  GI effects, Ulcers, Monitor for lab
platelet Antipyretic, Ischemic and renal function hemorrhage, abnormalities, s/s
 Aspirin(Aspirin)/ 81mg Tab/ QD aggregation stroke, TIA test dyspepsia of bleeding
 Acts on target
receptors to help
regulate the  Monitor for lab
metabolism of abnormalities,
carbs, fats and  HbA1c, serum hypoglycemia,
proteins. glucose, teach pt about
Stimulates liver electrolytes, K+ and appropriate use
 Insulin glargine(Lantus)/ 2units hepatic glycogen renal and liver and assess blood
SubQ/ TID synthesis DM 1 & 2 function tests.   glucose.