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‫األســــم‪:‬‬ ‫الى‪ :‬المختبر الريادي الجزئي‬

‫‪alitkan.info@alitkan.com‬‬ ‫البريد األلكتروني ‪:‬‬

‫العــــدد ‪S-26520/22 :‬‬

‫التاريخ ‪2022-01-21 :‬‬

‫الموضوع ‪ :‬تجهيز جهاز مختبري‬

‫تحيـــة طيبـــة ‪،‬‬

‫أشارة الى الموضوع اعاله ‪ ،‬يسرنا ان نقدم لكم عرضنا الخاص بنصب وصيانة الجهاز والتطبيقات اعاله علما‬
‫ان العرض شامل ما يلي ‪:‬‬

‫الشركة المصنعة ‪. BGI‬‬ ‫‪.1‬‬


‫طريقة الدفع ‪ %100 :‬عند توقيع العقد –( قابلة للتعديل الحقا ) ‪.‬‬ ‫‪.2‬‬
‫فترة التجهيز ‪ 3 :‬اشهر ‪.‬‬ ‫‪.3‬‬
‫يشمل العرض صيانة الجهاز مدة سنة ‪.‬‬ ‫‪.4‬‬

‫مع الشكر و التقدير‬

‫ع‪/‬الصيدالني سامي اسماعيل حمود‬


‫صاحب مكتب االتقان الطبي العلمي‬
‫لدعاية االدوية‬
# Category Decription QTY Unit Price Total Price

Equipment DNBSEQ 400 system 1


1 DNB Loader MGIDL-200RS (CE) 1 $480,000.00 $480,000.00
HALOS-AT2 , ( CE) . 1

Tech-transfer plan for hereditary cancer / Breakdown


1. Lab Design
2. Local installation and validation
3. Local training(lab operation training, quality system
construction, theoretical and practical courses)
2 WES tech transfer 1 $150,000.00 $150,000.00
4. Parallel test (experimental result data need to be
validated by parallel tests )
5. Kits needed for Parallel test
6. Remote technical support services (45 hours)
7.Foregin team visit per application

Exome Library Prep Kit (20 RNX)


Exome Hybridization Kit (12 rxn, 1rxn for 10 samples)
MGISEQ-2000RS High-throughput sequencing kit (PE100)
WES testing package(12RXN for 120 samples) 1 please see Note#3
MGIEasy Circularization Kit 1.0

Tech-transfer plan for hereditary cancer / Breakdown


1. Lab Design
2. Local installation and validation
3. Local training(lab operation training, quality system
construction, theoretical and practical courses)
3 Tech transfer / Hereditary cancer 1 $150,000.00 $150,000.00
4. Parallel test (experimental result data need to be
validated by parallel tests )
5. Kits needed for Parallel test
6. Remote technical support services (45 hours)
7.Foregin team visit per application

• Whole Blood Genomic DNA Extraction Kit

• BRCA1 and BRCA2 Gene Mutation Detection Kit V2


Panel Reagent Kit (64rxn, FCL, IVD) / Hereditary
(Combinatorial Probe-Anchor Synthesis Sequencing Method 1 please see Note#2
cancer
• Universal Sequencing Reaction Kit (G400 SM FCL PE100)

Tech-transfer plan for Lung cancer / Breakdown


1. Lab Design
2. Local installation and validation
3. Local training(lab operation training, quality system
construction, theoretical and practical courses)
4 NIFTY Tech transfer 1 $150,000.00 $150,000.00
4. Parallel test (experimental result data need to be
validated by parallel tests )
5. Kits needed for Parallel test
6. Remote technical support services (45 hours)
7.Foregin team visit per application

Nucleic Acid Extraction Kit (96 samples)


Detection Kit for Noninvasive Fetal Trisomy
(T21, T18, T13) Test
NIFTY Non invasive prenatal test reagent kits
(Combinatorial ProAnchor Synthesis 1 Please see Note#4
(DNBSEQ-G400)
Squencing Method) (96
samples)
Universal Sequencing Reaction Kit (G400 SM FCL SE35)

6 One year Warranty for the equipment One year


Note #1
* The same sequencer machine DNBSEQ 400 system can perform all the following
tech-transfer applications in future if needed against cost.

Table #1
Future Applications / Tech transfer
# Application
1 NIFTY
2 NIFTY pro
3 WES tech transfer
4 WGS
5 Pan-cancer Discovery- Tissue
6 Pan-cancer Discovery- ctDNA
7 Heriditary Cancer
8 Lung Cancer- Tissue
9 HPV tech transfer
10 PMSeq tech transfer

Note 2#
*Hereditary cancer Reagent Kit include 64 test / Unit Test price is 600$ / each test
can perform the following results:
# QTY UNIT PRICE
1 1 Test ( panel ) $ 600
Table #2

# Cancer
1 Breast
2 Ovarian cancer for female only
3 Prostate cancer for male only
4 Colorectal
5 Melanoma
6 Gatric
7 Endometrial cancer for femal only
8 Renal
9 Pancreatic
10 Bladder
11 Thyroid
12 Parathyroid
13 Multiple Endocrine Neoplasia
14 Neuofibromatosis
15 Pheochromocytoma
16 Familial paraganglioma
17 Rentinoblastoma
18 Chondrosarcoma
19 Gastrointerstinal stromal
20 Urothelial Carcinoma
21 Tuberous Sclerosis
22 Nephroblastoma
23 Neuroblastoma
24 Nevoid Basal Cell carcinoma
Note #3
*WES Reagent Kit include 120 test / please note the following:
The machine itself will generate the fasq raw date, BGI can help (F.O.C) to do an
interpretation for fasq data to the data which containing the variants of WES. Then
the customer needs further bioinformatics team to do the interpretation from this
variant to a readable mutations
# QTY UNIT PRICE
1 1 Test ( panel ) $ 650

The customer can directly send the wes data for BGI to do the analysis and
generate a readable report.
# QTY UNIT PRICE
1 1 Test ( panel ) $ 200

Note #4
*NIFTY Reagent Kit include 96 test / Unit Test price is 220$ / each test can
perform the following results:
# QTY UNIT PRICE
1 1 Test ( panel ) $ 220
Table #4

# NIFTY tests
NIFTY pro test : Detection Kit for
Noninvasive Fetal Trisomy (T21, T18,
T13) Test (Combinatorial ProAnchor
Synthesis) Squencing Method) (96)
Universal Sequencing Reaction Kit
(G400 SM FCL SE35(
1

Note #5
The following Items are not within the Scope of our offer and it must be supplied
by the customer:
Table #5

# Item Description
1 PCR Thermal Cycler
2 96-well PCR Freezer Box
4 Biosafety Cabinet
5 BMG Fluostar Omega
6 Centrifuge
7 Clean bench
8 Computer
9 Freezer
10 Fridge
11 Hygrothermograph
12 Internet Cable
13 Magnetic Rack
14 Microcentrifuge
15 Mobile UV light
16 PCR Freezer Box
17 Network Switch
18 PCR Thermal Cycler (qPCR)
19 Pipette (Single-channel)
20 Pipette (8-channel)
21 Refrigerator
22 Qubit4.0 Fluorometer
26 Timer
27 UPS battery
28 Uninterrupted power supply(UPS)
29 Water Bath
30 Vortex Mixer
31 Water Purifier

Note #6
Table #6
We can also offer oncology PCR products to detect mutations for Lung and
colorectal cancer
# Description Packe size Note Customer price IN USD
1 SENTIS ColoTect Kits (Detect corectal cancer) 50 tests/kit CE $ 175
Oncology
2 Detection Kit for 29 EGFR Mutations (PCR probing) 24 tests/kit CE $ 275
3 Detection Kit for 8 K-ras Mutations (PCR-Fluorescence Probing) 24 tests/kit CE $ 275

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