SEMI – DETAILED LESSON PLAN

GENERAL BIOLOGY 2
GAS 12
By: Shamarie Love R. Maribao

I. OBJECTIVES
Content Standard: The learners understand inheritance of Sex Linked characters.
Performance Standard: The learners shall be able to make a research paper/case
study/poster on transmission of a sex-linked genetic disease
Learning Competency: The learners shall be able to explain sex related inheritance and
recombination; illustrate the transmission of sex-linked characters; and distinguish sex-linked
traits from other sex-related traits (STEM_BIO11/12-IIIab-2).

Specific Learning Outcomes:

At the end of the lesson, the learners will be able to:
a. illustrate the transmission of an X-linked trait
b. participate willingly in answering and solving sex-linked word problems.
c. solve sex-linked word problems through a punnet square.

II. CONTENT: Sex-Linkage and Recombination

A. Learning Resources: Curriculum Guide (page 1), Teaching Guide (page 10-12)
B. Learning Materials: Visual Aids
C. Values Integration: Gratitude
Process Question:
1. Are you thankful with whatever you see whether it’d be good or bad?

III. PROCEDURE
A. Preliminary Activities
1) Prayer/Greetings
2) Checking of Attendance
3) Recalling of Classroom Rules
B. Developing Activities
1) Drill
a. Recall the difference between dominant and recessive traits.
b. Give students more examples of genotype test cross and let them identify the
resulting phenotype
2) Unlocking of Difficulties (Sex chromosomes, Sex-linked Trait, X-linked trait, Y-linked trait)
C. Activity
Group Activity - Picture Analysis

(Show the following pictures to the class)

Process Questions:
1) What figures do you see?
2) How do you feel about the activity?
3) What can you say about Dr. John Polidors’s percentage discovery about colorblindness?

D. Analysis
Tell the class that colorblindness is a sex-linked trait.

(Present the following illustrations of colorblindness inheritance.)

A B
Process Questions:
(A)
1) Who is the carrier of the trait?
2) Who are affected/carrier of colorblindness among the offspring?
3) How is the male offspring being the only one affected among the
siblings? (B)
4) Who has the trait in the family?
5) Who are affected/carrier among the siblings?
6) Why are there no offspring affected this time?

(Present the illustrations into a word problem and solve in a punnet square)
C – Normal; c - Colorblind

1) A woman who is a carrier for colorblindness (XCXc) marries a man with normal vision (XCY).
(A) What will be the phenotypes of the children? (B) Could there be anyone affected with
colorblindness? (C) If so, would the child be male or female?

Solution:
 2) A colorblind male (XcY) marries a female who is not colorblind (XCXC). (A) What are the
possible phenotypes of their children? (B) Chance of the male and female offspring to be
affected/carrier of the trait?
Solution:

Ask:
1) How are X chromosomes distributed among the offspring?
2) How about Y chromosome?
3) When will females be affected by an X-linked trait?

(Emphasize that Y-linked traits only affect males why X-linked traits can affect both sexes
but are only rare in females. Also, stress that X-linked can be dominant/recessive)

E. Abstraction
Ask:
1) What is sex-linked trait?
2) Are carriers of the trait also affected or not?
3) Why are X-linked traits more predominant in males and not in females?
4) When will females acquire an X-linked trait?
5) Why are females not affected by Y-linked traits?

F. Application

BOARD WORK (Word/practice Problems)

1) Hemophilia is a medical condition in which the ability of the blood to clot is severely
reduced, causing the sufferer to bleed severely from even a slight injury. This trait is said
to be X-linked recessive. If a woman who is heterozygous for hemophiliac (XHXh) marries
a normal male (XHY) What are the possible phenotypes of their children? Who will carry
and who will be affected by the trait?

2) Let us say hemophilia is an X-linked dominant trait. If a woman with homozygous

hemophilia (XHXH) marries a man who does not have hemophilia (XhY). What are the
possible phenotypes of their children?

IV. EVALUATION

I. Explain what is asked below:

1) What is sex-linked trait?
2) Why are males more predominantly affected with X-linked traits?
3) When will girls acquire an X-linked trait?

II. Solve the given problem

1) A colorblind male marries a female who is carrier for colorblind (heterozygous). What are the
 possible phenotypes of their children?

V. ASSIGNMENT
Solve the following Sex-linked problems at home.

1) A man whose mother is color blind marries a man with normal vision. (A) What is the
genotype of the husband? (B) What percent of their offspring can be expected to be
colorblind? (C) What percent of the male off-spring can be expected to be colorblind? (D)
What percent of the male off-spring can be expected to be carriers?

2) A particular sex-linked recessive disease of humans isn’t usually fatal. Suppose that a boy
with a disease lives past puberty and marries a woman heterozygous for the trait. (A) If they
have a daughter, what is the probability that she will have the disease? Hint: First,
determine the genotypes of the parents, then construct a punnett square cross, and analyze
the results.