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Contextualized Learning Resource (DCLR) in Science 10

The learners demonstrate the understanding of the formation stored


in DNA as being used to proteins, how changes in a DNA molecule
A. Content Standard
may cause changes in its product, and mutation occur in sex cells as
being heritable
The learners should be able to explain the importance of DNA as a
B. Performance Standard code of life by creating fictitious organism
Explain how mutation may cause changes in the structure and
function of a protein
(S10LT-IIIe-38)
C. Learning Competencies
 Using Magsanga festival and Municipal Founding Anniversary
celebration to explain or point out details of change/progress in
the local community and in the lives of the Meridanons (LHTM:
Festival and Dances)
I. OBJECTIVES At the end of the lesson the students should be able to:
a. Define mutation and its types;
b. Explore the various effect of mutation on human being; and
c. Valuing person with genetic syndrome or special needs
II. CONTENTS Heredity: Inheritance and Variation (MUTATION)
III. LEARNING RESOURCES
A. References

Teacher’s Guide Teacher’s Guide pp. 210-212


Learner’s Material Science 10 Learner’s Material pp. 282-293
Textbook Page
Additional Materials from Merida Cultural Mapping Outputs
Learning Resource (LR) Portal
B. Other Learning Resources https://www.youtube.com/watch?v=vl6Vlf2thvI
IV. PROCEDURES
A. Elicit TASK 1: 4 PICS ONE WORD
Show some pictures and let the students guess what the picture is all about
with the given hints.

__N__ M__T__N__

B. Engage Have the learners read the sentence below as an analogy representing the
strand of the DNA. (Literary Skill)

Sentence: THE FAT CAT ATE THE WEE RAT.


Question: Does the sentence make sense?

Ask the learners to consider the following changes in the sentence:

Sentence 1.1: THE FAT CAT ATE THE WET RAT.


1.2: THE CAT ATT HEW EER AT.
1.3: THE FAB TCA TAT ETH EWE ERA T.
Questions:
a. Identify the changes and describe how changes affect the
meaning/thought of the sentence.
b. What does each word in the sentence represents?
c. What does each letter represent?
TASK 2: GO GO CHANGING!
What can you observe from the two pictures below? In what manner do
these pictures imply about change in the community? Express your ideas.

C. Explore

TASK 3: LET’S TAKE A LOOK!


Let the students watch a short video clip about mutation.
Video Link: https://www.youtube.com/watch?v=vl6Vlf2thvI
Explain the topic using the following guide questions:
D. Explain
1. What is mutation?
2. Where do changes in mutation occur?
3. Differentiate two types of mutation.
4. Are all possible effects of mutation beneficial or harmful?
TASK 4: LET’S GET FOCUSED!
The teacher will further discuss the topic for better understanding.
1. What will happen to person who lacks a single chromosome? Or
he/she gets an extra chromosome?
E. Elaborate 2. Cite 2 examples of mutation in human or a genetic syndrome.
3. Why do you think mutation occur?
4. If you were a parent to a child with genetic syndrome or special
need, will you accept him/her? If yes, how will you treat your child?
If not, why?
F. Evaluate Multiple Choice: Read the questions carefully and write the letter of your
correct answer in a piece of paper.

1. Which of the following mutations results from one nucleotide being


substituted for another?
a. Deletion mutation
b. Insertion mutation
c. Frameshift mutation
d. Point mutation

2. Damage and errors in DNA cause


a. Mutation
b. DNA repair
c. Translation
d. Transcription

3. Which of the following describes frameshift mutation?


a. Insertion or deletion of nucleotides that results in a premature
stop codon.
b. Substitution of one nucleotide to another.
c. Insertion or deletion of a group of nucleotides that is multiple of
three.
d. Insertion or deletion of a group of nucleotides that is not a
multiple of three.
4. The technique known as karyotyping is used to detect abnormalities
in what?
a. Chromosomes
b. Ribosomes
c. Blood and urine
d. Amniotic fluid

5. Which of the following can a mutation cause?


a. Change in physical appearance
b. Change in an organism’s behavior
c. A change in the physiology of the animal
d. All of the above

TASK 5: AIM UP HIGH!


Make a multimedia presentation with the following questions below:

1. Having learned about mutation, as Meridanon, what sudden change


have you observed in our local community? Cite one example.
2. If you are the Mayor of the Municipality in Merida, in relation to
question no.1, what further change can you make to promote eco-
tourism?
OUTPUT RUBRIC
Good Need
Outstanding
Work Improvement
Criteria (5)
G. Extend (3) (1)
CONTENT
The content clearly depicts the
topic/ideas.
GRAMMAR & MECHANICS
Correctly uses subject and verb
agreement, capitalization, and
punctuation marks are
apparent.
CREATIVITY & NEATNESS
The output is free from
erasures and neatly done.

V. REMARKS/REFLECTION

PREPARED BY:

SHERRAMAE P. ARNAIZ
Teacher Applicant

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