Republic of the Philippines
Department of Education
SOCCSKSARGEN REGION
School Tacurong NHS Grade Level 10
Learning
Teacher Garren Jude V. Aquino Science
Area
DETAILED LESSON PLAN
Teaching
Date and Q3/Week 4 (9:00-10:00AM) Quarter Third
Time
I. OBJECTIVES
The learners demonstrate an understanding of:
1. The information stored in DNA as being used to make proteins;
A. Content Standards
2. How changes in a DNA molecule may cause changes in its product; and
3. Mutations that occur in sex cells as being heritable.
B. Performance Standards
C. Essential Learning Explain how protein is made information from DNA.
Competency S10LT-l1ld-37
OBJECTIVES:
K: Define DNA replication and transcription;
D. Objectives
U: Analyze the processes during DNA replication and transcription; and
D: Show how to replicate and transcribe a given DNA sequence..
II. CONTENT
A. Topic DNA REPLICATION AND TRANSCRIPTION
Chromosomes contain DNA inside the nucleus Replication is essential for cell division
to occur, Cell division is important for growth & development and repair of damage
tissues. DNA replication ensures that each-new-cell receives its own original copy of
B. Key Concepts DNA... A DNA is a double helix molecule composed of complementary strands of
deoxyribonucleotides units The complementary base pairs of the DNA are held
together by hydrogen bonds. In DNA (adenine (A) pairs with thymine (T) while guanine
(G) pairs with cytosine (C).
Analyzing, Understanding
C. Pre-requisite Skills
III. LEARNING RESOURCES
A. References
1. Teacher’s Guide
Pages
2. Learner’s Materials Science Learner’s Material, pp.263-268
Pages
3. Textbook Pages
4. Additional Materials
from Learning
Resource (LR) Portal
B. Other Learning Quarter 3 Week 4; LAS 9
Resources
DNA Replication:
1. Websites https://www.genome.gov/genetics-glossary/DNA-Replication#:~:text=DNA
%20replication%20is%20the%20process,with%20its%20own%20complete%20genome.
2. Books/Journals
C. Materials Laptop, Cellular Phone
Preliminaries: Prayer, checking of attendance, setting of standards, and review of the
IV. PROCEDURES
past lesson.
ELICIT Prerequisites: Students should be familiar with
DNA - Deoxyribonucleic acid (DNA) is an organic chemical that contains
genetic information and instructions for protein synthesis. It is found in most
cells of every organism.
Chromosomes - Chromosomes are thread-like structures located inside the
nucleus of animal and plant cells. Each chromosome is made of protein and a
single molecule of deoxyribonucleic acid (DNA).
Nucleus - A nucleus, as related to genomics, is the membrane-enclosed
organelle within a cell that contains the chromosomes.
Replication - the action or process of reproducing or duplicating replication
of DNA
Cell division - Cell division is the process by which a parent cell divides, when
a mother cell divides into two or more daughter cells.
Republic of the Philippines
Department of Education
SOCCSKSARGEN REGION
Thymine - one of the four nucleobases in the nucleic acid of DNA. Pairs with
Adenine.
Guanine - one of the four nucleobases in the nucleic acid of DNA. Pairs with
cytosine.
Adenine - one of the four nucleobases in the nucleic acid of DNA. Pairs with
Thymine during DNA replication and uracil during transcription.
Cytosine - one of the four nucleobases in the nucleic acid of DNA. Pairs with
guanine.
Uracil - one of the four nucleobases in the nucleic acid RNA. Pairs with
Adenine.
Pair It!
Direction: The sequence of bases in one DNA strand is given below. Identify the
complementary sequence of bases in the other strand of DNA.
ENGAGE
Chromosomes contain DNA inside the nucleus. Replication is essential for cell division
to occur. Cell division is important for growth & development and repair of damage
tissues. DNA replication ensures that each-new-cell receives its own original copy of
DNA.
A DNA is a double helix molecule composed of complementary strands of
deoxyribonucleotides units. The complementary base pairs of the DNA are held
EXPLORE together by hydrogen bonds. In DNA, adenine (A) pairs with thymine (T) while guanine
(G) pairs with cytosine (C).
EXPLAIN DNA replication is a process of producing two identical replicas of DNA from one
original DNA molecule. It happens during interphase, specifically in S phase.
Transcription is the process by which the information in a strand of DNA is copied into
a new molecule of messenger RNA (mRNA). There are three major types of RNA that
help build proteins: mRNA, rRNA and tRNA.
Republic of the Philippines
Department of Education
SOCCSKSARGEN REGION
Messenger RNA (mRNA) brings information from the DNA in the nucleus to the protein
manufacturing area, the cytoplasm. In the cytoplasm, the mRNA becomes the template
of information to makes proteins. Ribosomes, made of ribosomal RNA (rRNA), and
ribosomal proteins hold tightly into the mRNA using its information to assemble the
amino acids in correct order. Transfer RNA (tRNA) supplies amino acids to the
ribosome to assembled as protein.
The following events can help you understand the process of transcription:
Step 1. Ribonucleic Acid polymerase enzyme binds and opens the DNA molecule that
will be transcribed.
Step 2. As the DNA molecule opens, the RNA polymerase slides along the DNA strands
and links free RNA nucleotides that pair with nitrogenous bases of the complementary
DNA strand. Hence, if the sequence of the bases on the DNA strand were CCG TTA
CAT, the sequence of bases on the RNA strand would be GGC AAU GUA (In RNA,
Adenine(A) is paired with Uraci(U) while the remaining bases remain in their pairs: T-
A, C-G and G-C).
Step 3. When the process of base - pairing is completed, the RNA molecule breaks
away as the DNA leaves the nucleus and goes to the cytoplasm.
DNA Replication and Transcription
a. Replicate the given sequence below
Adenine
Cytosine
Thymine
Guanine
ELABORATE
Thymine
Adenine
Adenine
Cytosine
Guanine
b. Transcribe the replicated DNA above.
The students will answer the following questions:
1. What is DNA replication and transcription?
2. What happens during DNA replication and transcription?
EVALUATE
3. Replicate and transcribe the sequence:
GCATCGATTAAC
Assignment:
EXTEND
Search and draw the Genetic Code Table in a short bond paper.
V. REMARKS
VI. REFLECTION
Republic of the Philippines
Department of Education
SOCCSKSARGEN REGION
A. Number of learners
who earned 80% in the
evaluation.
B. Number of learners
who require additional
activities for remediation
who scored below 80%.
C. Did the remedial
lessons work? Number of
learners who have caught
up with the lesson.
D. Number of learners
who continue to require
remediation
E. Which of my
teaching strategies
worked well? Why did
these work?
F.What difficulties did I
encounter which my
principal or supervisor can
help me solve?
G. What innovation or
localized materials did I
use/discover which I wish
to share with other
teachers?
Prepared by:
GARREN JUDE V. AQUINO
Pre-Service Teacher
Checked & Observed:
ARMELA S. ALAMON
Cooperating Teacher
