Professional Documents
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2. Motivation
Complete Me Game: The students will be asked to General instruction: All your output will be sent via
complete the sentences below. SHAP email. Take a picture of your book with your
answer and send it in PDF. 1 point each question.
Deadline of all activities will be on September 1 not
later than 2PM
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
TEST YOURSELF
Upon seeing the A. Presentation (These presentations will be sent
picture. What pops- to students as their reference)
up on your mind. You ⮚ MEIOSIS II
have 1minutes to
scrutinize the picture.
And later we will have
a little bit sharing. The goal of meiosis II is to divide sister chromatids,
resulting in sex cells with only half the chromosome
number.
3. Statement of Aims
The students will be asked to read the objectives of
the lesson.
B. Presentation
This time is the discussion of the life cycle, below are
to be discussed and shown on the PowerPoint:
⮚ Sperm Sorting: The solution to Choosing
Your Baby’s Gender ⮚ Prophase II
What is the possibility of choosing the gender of your
child prior to conception? Can the use of Prophase II begins immediately after cytokinesis – the
reproductive technology allow you to have that splitting of the diploid gamete into two haploid
power? There are many reasons that drive couples to daughter cells. In order to prepare for the next
the gender selection process. Gender selection is an division, prophase II condenses chromatin first into
option today for couples who do not want to pass on chromatids, and then more tightly into chromosomes.
sex-linked genetic disorders. Other couples’ resort to Simultaneously, the nuclear membrane dissolves,
gender selection to balance gender in the family. leaving an open area of cytoplasm in which a network
Whatever the reason, there has been an intense debate of proteins (microtubules) has enough space to create
on the ethical use of reproductive technologies to pathways reaching from one side of the cell to the
select the gender of the child. Critics of the other – the spindle apparatus. After the condensing of
reproductive technique argue that selecting the chromatin into chromosomes, and after the
gender of the children will allow parents to treat them disintegration of the nuclear envelope containing these
simply as commodities, to open a door for genetic chromosomes, the centrosomes migrate to either pole.
manipulation, and to drive gender imbalance among Even in the absence of centrosomes, the
populations. reconstruction of the spindle apparatus used during
meiosis I can be initiated. These four steps
characterize prophase II.
⮚ THE HUMAN LIFE CYCLE AND
SEXUAL REPRODUCTION
Long term survival on earth requires some form of
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Telophase II
During telophase II, the fourth step of meiosis II, the
chromosomes reach opposite poles, cytokinesis
occurs, the two cells produced by meiosis I divide to
form four haploid daughter cells, and nuclear
envelopes (white in the diagram at right) form. When
In the human life cycle, the process of meiosis is telophase II is over, the two cells are entirely
important to reduce the number of chromosomes
separated, and their nuclear membranes are fully
from diploid (2n=46) to haploid (n=23). This
reduction in the number of chromosomes is essential formed. Meiosis is then complete.
in order to restore the chromosome number once a
sperm unites with an egg during fertilization. The 46
chromosomes found in the diploid cells of humans Table 1: Differences Between Mitosis and Meiosis
are therefore maintained from one generation to the
Mitosis Meiosis
next through the cycle of meiosis, and then followed
by fertilization and mitosis. Without meiosis, the One cell division Two cell divisions
chromosome number of the body cells will double in
each generation, which may lead to abnormalities in Homologous Homologous
each population. More importantly, maintaining the chromosomes never pair chromosomes pair up
correct number of chromosomes ensures the survival along the equator
of the organism. A change in the chromosome
number may be harmful to an individual. Anaphase: sister Anaphase 1: sister
Nevertheless, change in the number of chromosomes chromatids separate chromatids remain
in some locations can be beneficial for the evolution together
of or giving rise to new species. Results in two diploid cells Results in four haploid
cells
C. Comparison and Abstraction
The teacher will ask the following questions to the
students. EXPLORE: 5pts each
How can you relate this Human Life cycle into your
life as your obstacle as a student and how did you General Direction: General Instruction: Please follow
enjoy life after all of those? the below format in making your activity: send it here:
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
vidal.joshua@shap.edu.ph
D. Generalization File: MS Word
The students will be asked to complete the sentence. Font type: Times New Roman
I realized that______________________________. Font size: 12
And the human life cycle is a___________________. Paper size: 8.5 x 11 (Letter size)
Truly life could be so complex Deadline: September 11 not later than 3PM
but_________________________________.
Haploid Diploid
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
RUBRICS
Description 0pt. 1pt. 2pts.
Coherency No attempt Has point but Has point,
not exact exact, precise
and anchored
to the
discussed topic
Organization No attempt Attempted to At least 2
of thought write but errors in
(grammar, misleading Subject
punctuations) thoughts agreement, and Rubrics
at least 3 in
punctuations. Description 0pt. 1pt. 2pts.
Uniqueness of No attempt Has work, no Not applicable Coherency No attempt Has point but Has point,
answer similarities of not exact exact, precise
answer to and anchored
other to the
classmates. discussed topic
Organization No attempt Attempted to At least 2
of thought write but errors in
(grammar, misleading Subject
END OF CLASS punctuations) thoughts agreement, and
at least 3 in
punctuations.
Uniqueness of No attempt Has work, no Not applicable
answer similarities of
answer to
other
classmates.
Activity 2.
⮚ Importance of Meiosis
Meiosis is important because it ensures that all
organisms produced via sexual reproduction contain
the correct number of chromosomes. Meiosis also
produces genetic variation by way of the process of
recombination. Later, this variation is increased even
further when two gametes unite during fertilization,
thereby creating offspring with unique combinations
of DNA. This constant mixing of parental DNA in
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Significance
1.Meiosis is responsible for the formation of sex cells
or gametes that are responsible for sexual
reproduction.
2.It activates the genetic information for the
development of sex cells and deactivates the
saprophytic information.
3.It maintains the constant number of chromosomes
by halving the same. This is important because the
chromosome number doubles after fertilization.
4.In this process independent assortment of maternal
and paternal chromosomes takes place. Thus, the
chromosomes and the traits controlled by them are
reshuffled.
5.The genetic mutation occurs due to irregularities in
cell division by meiosis. The mutations that are
beneficial are carried on by natural selection.
6.Crossing over produces a new combination of traits
and variations.
⮚ Crossing-Over
As mentioned above, crossing-over occurs during
prophase I, and it is the exchange of genetic material
between non-sister chromatids of homologous
chromosomes. Recall during prophase I, homologous
chromosomes line up in pairs, gene-for-gene down
their entire length, forming a configuration with four
chromatids, known as a tetrad. The process of pairing
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
LOOP ACTIVITY
SEXUAL ASEXUAL
REPRODUCTION REPRODUCTION
SIMILARITIES
5pts
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
DIFFERENCES
ADVANTAGES
DISADVANTAGES
Meiosis Mitosis
Wrap-Up
Using the generated item analysis, the teacher will
review the result in order to decide whether
reinforcement is needed. The learner who failed to
submit the assessment will be given a short narrative
feedback through email.
END OF CLASS
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
Date: Date:
I. Learning Outcomes
1.Differentiate the differences of the cells in the
body;
2. Define the function of blood cells, bone cells,
gland cells, muscles cells, nerve cells, reproductive
cells; and
3.Awareness and appreciation of the mainly function
of cells in the human body.
A. Preparation
1. Apperception
⮚ Prayer
⮚ Attendance
The teacher will pick a name to give an insight about
the previous topic
2. Motivation
TELL ME!
Before we proceed, can you use this acronym to
relate in Human Reproductive.
Possible Answer:
L-
I- L- Living organisms undergo phases to become whole;
F- and every
E- I- individual deserves to live and to enjoy life; and we all
know that
B. Presentation (PowerPoint)
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Meiosis
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ MEIOSIS I
Before meiosis starts, the DNA has been replicated or
copied in the germ cell. Meiosis I focused on the
division of homologous chromosomes to produce two
haploid cells with duplicated chromosomes. Figure
below summarizes the activities on the stages of
meiosis I involve only few chromosomes to simplify
the illustration.
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
It the phase of a
replicated chromosome
condensation
The chromosomes
condense and become
compact and visible hence
making it possible to
distinguish between sister
chromatids.
The chromosomes
appear like strings with beads
and the beads are known as
⮚ Zygotene
also known as zygonema.
● This is the phase where homologous
chromosomes associate closely to forms pairs
of chromosomes, a mechanism known as
synapsis. The pairs of chromosomes have
four chromatids (tetrads).
● The synaptic association forms up and down
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
Pachytene
This is the phase where the crossover of genetic
materials takes place between non-sister chromatids
i.e. pairs of homologous chromosomes. This forms
chiasmata.
● Crossing over is achieved by synapsis by the
attachment created by the chromatid in a
homologous chromosome.
● The synapses complete the crossing over of
genetic information, creating a variation in
the genetic materials due to the exchange
between the mother and father genetic
elements.
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Diplotene
This is the stage of synaptonemal complex
disappearance while the homologous pairs remain
attached at the chiasmata.
● The disintegration of the synaptonemal
complex occurs between the two
chromosomal arms causing repulsion of the
arms.
● This causes the chromosomes to move apart
from each other while still being held by the
chiasmata.
● The chromosomes then start to uncoil slowly,
and the chiasmata can be visualized
microscopically, and they can be seen moving
close to the ends of the chromatids. This
process is known as terminalization.
⮚ Diakinesis
The fifth and final phase of prophase I. It sets up the
cell for metaphase.
● It takes place after the chromatids have
condensed and the sister chromatids are
bivalent of tetrad as visualized under a
microscope.
● The chiasmata finally arrive at the end of the
chromatid arms of the chromosomes
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
finalizing terminalization.
● the Chromosomes become more condensed
but remain connected by the chiasmata and
cannot move further toward the poles.
● At this stage the nucleolus and the nuclear
envelope dissolves allowing the centrioles
(the centrosome forming microtubules) that
form the mitotic spindle, to migrate freely
along with the remaining spindles formed
during mitosis.
⮚ Metaphase I
In meiosis I, the lining-up stage of metaphase I is
relatively rapid. Tetrads or bivalents (a pair of
chromosomes with four chromatids (2 originals, 2
copies) are pulled into line at what is known as the
metaphase (or equatorial) plate. This plate does not
actually exist but is an imaginary central line along
which the chromosomes are positioned. In metaphase
I, the two chromosomes of a homologous pair face
opposite poles. As recombination has taken place,
each of the four chromatids (and, of course, both
homologous pairs) have slightly different genetic
material. Further steps will pull one of the
homologous pair to one end of the cell, and the other
to the opposite end. This means that the resulting two
cells (produced during cytokinesis at the end of
meiosis I) will contain full sets of chromosomes, but
these will not consist of chromosome pairs.
Figure 7:
Metaphase in
an onion cell
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Anaphase I
Meiosis consists of two consecutive cell divisions,
with no DNA replicated in between. This means that
a diploid organism, containing two alleles for each
gene, will be reduced to a haploid organism, with
only one allele at each gene. These alleles are
separated during anaphase I. Before meiosis, the
DNA is duplicated, again producing sister chromatids
bound together as single chromosomes. These
chromosomes have homologous pairs, which contain
the other alleles for the genes on the chromosome.
These chromosomes are also duplicated into sister
chromatids. During meiosis I, the homologous
chromosomes are separated. The homologous
chromosomes become bound together during
prophase I of meiosis, by similar molecules of
cohesion that bind sister chromatids. As the meiotic
spindle sets up during metaphase I, the cell ensures
that each homologous pair becomes attached to
microtubules from each side of the cell. These
microtubules then pull against Theeach
microtubules
other tostay attached
move the
to the kinetochore after the
homologous pairs to the metaphase plate. During the
cohesions are broken apart. The
time the pairs are bonded, they can exchange genetic
kinetochore microtubules then
information in a process called recombination. When
shrink towards the centrosomes
the homologous pairs are separated during anaphase
(not pictured), which pulls the
I, the DNA variations become chromosomes forapart.
destined different
Non-
cells, ensuring variability in kinetochore
a population’s genetics.
microtubules grow
in the opposite direction,
expanding the cell and further
separating the chromatids.
Conventionally, sister
chromatids are called sister
chromosomes once they
separate, as they contain the
same information and will
function independently in their
new cells. After the
chromosomes have been fully
separated, a nuclear envelope
will form and
the cytoplasm will be divided in
the final steps of cell division.
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
⮚ Telophase I
At each pole, during this stage, there is a complete
haploid set of chromosomes (but each chromosome
still has two sister chromatids). A cleavage furrow
appears, and by the end of this stage the parent cell
has divided into two daughter cells. This separation
of the cytoplasm is called cytokinesis. In some
organisms nuclear envelopes appear briefly at this
point (this intermediate stage is called interkinesis).
But in others the daughter cells begin immediately to
prepare for the second meiotic division.
D. Generalization
The teacher will ask one student to give a conclusion
of the discussion
Sacred Heart Academy of Pasig
M. Suarez Ave. (formerly Market Ave.), Maybunga Pasig City
SY 2020-2021
Metaphase I Conclusion
Anaphase I Conclusion
Microtubules Conclusion
Telophase I Conclusion
IV. Assessment
General Instruction: Please follow the below format
in making your activity: send it here:
vidal.joshua@shap.edu.ph
File: MS Word
Font type: Times New Roman
Font size: 12
Paper size: 8.5 x 11 (Letter size)
Deadline: September 9 not later than 6PM
END OF CLASS