PRESS RELEASE

AMOEBA extends its commercial cover with the signature of a new

letter of intent with OXIDINE to distribute BIOMEBA in Spain

Lyon, Bergondo, 15th December 2016 - AMOEBA (FR0011051598 - AMEBA), the producer of a
biological biocide capable of eliminating the risk of waterborne bacteria, announced today that it has
signed a Letter of Intent (LOI) with OXIDINE prior to entering into a definitive agreement regarding the
distribution of its BIOMEBA product in Spain. This agreement is subject to marketing authorization
(MA) that may happen during the first semester of 2017.

This new agreement is strengthening the existing sales network of AMOEBA in Europe and allows the
company to enter the Spanish market. Located in the north west of Spain, OXIDINE is present on the
autonomous regions of Galicia, Asturias, Basque country, Navarre, Castilla and León as well as the
region of Madrid. AMOEBA now counts a total of 11 distributors spread over the European and
American continents.

Last September, the Spanish authorities granted AMOEBA the Marketing Authorisation for R&D
purposes for 10 Industrial sites. AMOEBA can now speed up the planning of tests during the course of
2017.

« The signature of this agreement confirms our determination to associate ourselves to an innovative
company in the industrial water treatment sector. BIOMEBA product represents a true alternative to
chemicals biocides. » stated José Manuel VILELA, General director of OXIDINE.

« The agreement signed with our partner, OXIDINE, allows us to extend our commercial cover to a new
territory in Europe. Spain represents an important market for AMOEBA bearing in mind the high level
of exigence from the Spanish regulatory authorities against the risk of legionella. » added Fabrice
PLASSON, President of the Board of AMOEBA.

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About OXIDINE: Created in 1997, OXIDINE is based at A Coruña in the northwest of Spain. Main actor
of water treatment in the industrial sector, OXIDINE commercialize a wide range of innovative products
and services in several areas, Galicia, Asturias, Basque Country, Navarre, Castilla and León and the
Madrid region. Our experimented teams developpe tailor-made solutions according to our customers’
needs established after a detailed study of each case. For more information: www.oxidine.net

About AMOEBA: AMOEBA develops a biological biocide capable of eliminating waterborne bacterial
risk (legionella, pseudomonas, listeria, etc.). This entirely natural solution is presented as an alternative
to the chemical treatments traditionally used in the industrial sector and complies with the new
regulations in terms of chemical emissions into the environment. In a worldwide market for chemical
biocides estimated to be worth EUR 21 bn(1), AMOEBA is today concentrating on the segment of
industrial air-cooled towers (ACT), estimated to be worth EUR 1.7bn (2). AMOEBA is pursuing the
regulatory procedures to obtain the provisional MA for all European countries in “Cooling Towers”
application. Based in Chassieu – France. AMOEBA is quoted on compartment C of the Euronext Paris
stock exchange and joined the CAC® Small index. For more information: www.amoeba-biocide.com.

(1) : Sources combined by Amoeba from water treatment agencies, Freedonia, Eurostat and MarketsandMarkets
(2) : Amoeba data combined from the following sources: DRIRE 2013, Eurostat, ARHIA 2013

Contacts :

Amoeba Actifin
Nathalie COMBROUSSE Ghislaine GASPARETTO
Marketing Communication Manager Financial Communication
+33 (0)4 81 09 18 15 +33(0)1 56 88 11 11
nathalie.combrousse@amoeba-biocide.com ggasparetto@actifin.fr