Abstract

Antiglaucoma medications are often associated with ocular adverse reactions such as dry eye,
and burning or stinging sensations. These undesirable effects may lead to treatment
discontinuation and reduced quality of life in patients with glaucoma. Antiglaucoma medications
usually contain benzalkonium chloride (BAK) as a preservative. Animal studies, in vitro studies
and in vivo experiments have demonstrated various adverse effects of BAK. Clinical studies
have also shown an increased incidence of adverse events with BAK and have demonstrated
that the withdrawal of preservatives reduces these effects. Collectively, these data suggest that
preservative-free antiglaucoma treatments have clinically relevant benefits for patients.

bstract: Jute (Corchorus spp.) leaf has long been used as a remedy in many cultures. Jute leaf products,
which include the leaf juice, fried leaf, and some time whole green leaf, are used, among other reasons,
as laxatives, in creams for skin care, and as a treatment for a wide range of diseases, respectively.

Tossa and white jute varieties are thought to be native to Bangladesh and India, and are also the world's
producer. It is grown for both fiber and culinary purposes. It is used as an herb in Middle Eastern and
African countries, where the leaves are used as an ingredient in a mucilaginous potherb called
"molokhiya" (‫ ية لوخ م‬,of uncertain etymology).