Name: ________________________________________ Rating: ______________

Instructor: _____________________________________ Yr. & Sec.: ___________

Experiment 6
PREPARATION OF AMMONIUM BROMIDE

I. Objective: To prepare ammonium bromide from potassium bromide and

ammonium sulfate.

II. Materials:

Potassium bromide Watch Glass

Boiling water Beaker
Ammonium Sulfate Tripod
Ethyl Alcohol Wire Gauze
35% Ethanol Stirring Rod
Sodium hydroxide Funnel
Silver Nitrate T.S. Filter Paper
Chloride T.S. Cotton
Evaporating dish Water Bath
Bunsen burner Graduated Cylinder
Test tube Test tube rack

III. Procedure:

1. Weigh 12 g of potassium bromide and 6.5 g ammonium sulphate

separately.
2. Dissolve the potassium bromide in 12.5 mL boiling water.
3. Dissolve the ammonium sulphate in 7.5 mL boiling water.
4. Mix the 2 boiling solutions and stir well.
5. Cool the mixture to about 70oC and add 20 mL of alcohol.
6. Cool the mixture to room temperature.
7. Filter the mixture through a pledget of cotton placed in a funnel and
wash the residual salt with 35% alcohol.
8. Evaporate the filtrate on a water bath and allow the salt to crystallize.

IV. Identification Test

A. Physical Test

Describe the color, odor, taste, physical state and appearance of product
obtained.
 B. Chemical Test:

1. Reaction with sodium hydroxide

To 5 ml of ammonium bromide solution add 5 ml of sodium hydroxide
solution when warm the mixture. Note the evolution of gas and its odor.

2. Reaction with silver nitrate T. S.

To 5 ml of ammonium bromide solution add 5 ml of silver nitrate solution.
Note the product formed.

3. Reaction with chloride T.S.

To 5 ml of ammonium bromide solution add chloride T.S. drop by drop.
Then add 5 ml of chloroform and shake the mixture. Observe the color in
the chloroform layer.

V. Results obtained in the identification tests.

A. Physical Test

1. Color_____________________________________________________

2. Odor _____________________________________________________

3. Taste _____________________________________________________

4. Physical State ______________________________________________

Appearance ________________________________________________

Reaction with sodium hydroxide

Reaction with silver nitrate
 Reaction with chloride

VI. Reaction Involved in the preparation of ammonium bromide.

1. Reaction with sodium hydroxide

____________________________________________________________

Chemical Equation Involved:

____________________________________________________________

2. Reaction with silver nitrate T.S.

____________________________________________________________

Chemical Equation Involved:

____________________________________________________________

3. Reaction with chloride T.S.

____________________________________________________________

Chemical Equation Involved:

____________________________________________________________

VII. Pharmaceutical Use of Ammonium Bromide.

________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________.
VIII. Answer the following Questions:

1. What is the pharmaceutical application of ammonium bromide?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

2. What are the different pharmaceutical preparations containing ammonium

bromide?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

3. What is the therapeutic use of bromides?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

4. What is the common therapeutic use of bromides?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

5. What are the other compounds of bromides which is useful as medical

agents?
___________________________________________________________
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___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________
 6. What is the computation in preparing 35% ethyl alcohol?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

7. What is the reason of dissolving separately potassium bromide and

ammonium sulphate in boiling water?

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
_____________________________________________________

IX. CONCLUSION:

___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
__________________________________________________.
Name: ________________________________________ Rating: ______________
Instructor: _____________________________________ Yr. & Sec.: ___________

Experiment 7
PREPARATION OF CALCIUM CARBONATE

I. Objective: To prepare calcium carbonate from sodium carbonate and calcium

chloride.
II. Materials:
Sodium carbonate Test tube
Calcium chloride Distilled water
Nitric acid Beaker
Silver nitrate Tripod
Acetic acid Wire Gauze
Ammonium Oxalate T. S. Stirring Rod
Mortar and Pestle Funnel
Evaporating dish Filter Paper
Bunsen burner Graduated cylinder
Test tube rack

III. Procedure:
1. Dissolve 6 g of sodium carbonate and 7 g of calcium chloride
separately in 50 mL of distilled water.
2. Filter the solutions.
3. Warm both solutions to about 60OC.
4. Pour the calcium chloride solution into the sodium carbonate solution
and stir the mixture constantly.
5. Filter the mixture and collect the precipitate.
6. Wash the precipitate repeatedly with warm water.
7. Dry the precipitate in an oven set at 600C and then powder finally using
mortar and pestle.

IV. Identification Test

A. Physical Test

Describe the color, odor, taste, physical state, and appearance of product
obtained.

B. Chemical Test

1. Reaction with acetic acid

To 2 ml of calcium carbonate solution add 2ml of acetic acid and take note
of the gas procedure.

2. Reaction with ammonium oxalate T.S.

To 2 ml off calcium carbonate solution add 2 ml of ammonium oxalate T.

S. Observe the formation of precipitate.

3. Flame Test
 Moisten calcium carbonate with hydrochloric acid. To this mixture, dip the
nichrome wire and place in on the Bunsen burner flame. Note the color
produced in the on-luminous flame.
V. Results obtained in the identification test of calcium carbonate

A. Physical Test
1. Color: __________________________________________________
2. Odor: __________________________________________________
3. Taste: __________________________________________________
4. Physical State: ___________________________________________
5. Appearance: ____________________________________________

Reaction with acetic acid Reaction with ammonium oxalate

FLAME TEST

VI. Reaction Involved in the preparation of calcium carbonate.

B. Chemical Test
1. Reaction with acetic acid __________________________________
Chemical Equation Involved:
_________________________________________________________

2. Reaction with ammonium oxalate ___________________________

Chemical Equation Involved:
__________________________________________________________

3. Flame Test._______________________________________________
 Chemical Equation Involved:

_________________________________________________________
VII. Pharmaceutical use of Calcium carbonate.

________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________

VIII. Answer the following questions:

1. Give the pharmaceutical application of calcium carbonate.

________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
__________________________________________________

2. Enumerate the different pharmaceutical preparations which contain

calcium carbonate.
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________

3. What are the different forms of calcium carbonate?

________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
________________________________________________________
______________________________________________.

IX. CONCLUSION:

________________________________________________________
________________________________________________________
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________________________________________________________
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______________________________________________.