Professional Documents
Culture Documents
القسم الثالث كان اغلبه كلينيكال متوسط الصعوبة وفيه عدد ال بأس به من التجميعات
ال تنسونا من دعواتكم ونتمنى لكم التوفيق
Digoxin
Warfarin
Amiodarone
Celecoxib
PPI Metoclopramide
Lisinopril
Glibenclamide
Pioglitazone
Metformin
Case about pt taking multiple drugs and he has dizziness when he stands, the responsible
drug is?
Hydralazine
Isosorbide dinitrate
Case about pt taking Methotrexate and has anemia what is the best drug for his case?
Folic acid
Enzyme inhibitors
Case about pt with hypothyroidism taking levothyroxine try to conceive and asked the
pharmacist about this drug?
Continue levothyroxine
Stop levothyroxine
Gabapentin
Statin
ACEIs
Simvastatin
Atorvastatin
Simvastatin
Atorvastatin
Mirtazapine
Bupropion
Chlorpromazine MoA?
Lamotrigine
Phenytoin
Four weeks
Six weeks
Contraindicated in pregnancy
Finasteride
Albuterol
Fluticasone
Case about pt with renal transplantation taking tacrolimus and a new drug causes an
indication?
Unfractionated heparin
Enoxaparin
Warfarin
Warfarin lab result?
Gum bleeding
Meropenem
Moxifloxacin or levofloxacin
Azithromycin
Enoxaparin antidote?
Protamine
Acetaminophen antidote?
Acetylcysteine
Clopidogrel metabolism?
CYP 2C19
Topical hydrocortisone
Oral hydrocortisone
2.5
15
20
Xalatan drops used for?
Amebiasis: Ipecac
Ramelteon MoA
Melatonin agonist
Melatonin antagonist
Plasmid
Peptidoglycan
Question about a pregnant woman when she can take a flu jab?
Systematic review
Case control
Cohort study
A doctor noticed a new side effect for a drug, what study should he wrote?
Case control
Clinical trial
Hypersensitivity reaction type II
IgG
IgE
IgM
IgA
Crcl calculation
Bioavailability calculations
Cool room
Warm room
Structure questions:
Amphetracin B (hydrolysis)
Paracetamol (h-bond)
Sulphonylurea
Antidote :
- Iron
- Morphine
- antidote of opioid
- Antidote of dabegatran
- Diazepam inactive
- Antidote heparin
- Benzodiazepine
- antidote of midazolam
- Mydriasis antidote : flumazil IV - IM – Naloxone IV – IM )
- NALOAXONE dose in pedia
-
-
Structure :
- Antimalaria
- Selenium
- Erythromycin
- Ergotamin
- Acyclovir
- Ethambutol
- Barbiturates
- common pharmacophoreبيقولي
- lactone ring ithink
- Barbiturates ring
- conjugated amine
-
- analgesic for dysmenorrhea ? chose from structure
- which part of structure bind to nicotin receptor
- codeine → morphine ()او العكس
-
- Phenytoin SAR
- Photo oxidation
- عالج يستخدم للزهايمر بس ممنوع عشانه يحتوي ع امفيتامين
- Ranitidine SAR
- Structure of TCA the most effective one the choice are imipramine,cholormipramine
and the others are wrong structure
- Structure of ethosuximide
- Structures containing sulpha gr and choose which one safe with sulphuric allergy
- Bio isoster of indomethacin
- Major metabolite of diclofenac
- Structure of paracetamol c8h9no2
- advantage od pseudoephedrine over ephedrine?
- What we can to add on morphine structure to increase its activity? Add OH group at
position 14
- physostigmine vs pyridostigmine structure and ask about replace pyridostigmine
from the formulary
8-2022 اختبارات
TAHANI
Calculation :
- Crcl
- Ld
- Absolute bioavailability
- BMI
- calculate half life
- Bioavailability equation
- Cl equation
- مل قطره عين٣ المسأله تبع كم عدد النقط في
- Dose that give conc at 4hr (vd and Kel just are given)
- Phenytoin 300mg in 10ml with conc 75g/ml and diluted with D5%to 25mg/ml what
is the conc of both phenytoin and D5%
- Vancomycin correction
- Osmolarity : ++
- Clearance : ++
- Clearance → cl= elimination /dose
-
Anticoagulant :
- More
- Vitamin k and
- warfarin
- ايش اللي ينأخذ مع االكل
- Anticoagulant for pregnant
- +1
- Antiplatlet CI in TIA
- Chadsvasc score for 60year htn and dm
- atrial fibrillation patient with a CHA2DS2-VACS score of 2 ??? man or women
- INR range Mittral valve
- INR DVT
- Vegan diet and INR ( Increase – decrease – no change IN INR )
- Extrinsic pathway in clotting occure by : tissue trauma
-
-
Immunity :
- iGg
- iGm
- iGe
- NK cell function
- Ig found in colestrim
8-2022 اختبارات
TAHANI
Bioche:
vomiting
- ginger
- vitamin b6
vaccine
8-2022 اختبارات
TAHANI
Women
Definition:
- Privilege
- Budget
- Incident
- Morbidity
- Pharmacoepdemiology
- Planning
- Accounting
- Incidence
- Quarter tablet Definition
- Management
- MIC
- Accouting
- HAM
- Pharmaceutical psuchology
-
Study :
- 4q
- STUDY rear disease
-
- Phase post market
- +1
- group of smokers and non smokers , observe which will develope lymphoma and
which don't ... what's the kind of study
- which type of data the researchers collect from patients direct? (primary, 2ed , lab)
- clinical pharmacist during the round they ask her to choose one antibiotic for
C.diff,and after searching she found that vancomycin orally bid is the best to choose
,from where she conduct the information?
a) -expert opinion
b) -cohort study
c) -rct not su
-
8-2022 اختبارات
TAHANI
Communication
- assertive
infectious:
- Mrsa
- Mssa
- What it have oral good activity cephalosporin ?
- Colostine high dose monitor ?
- - سؤال الsensitivity test اللي اجابتهmethicillin
- - encapsulated yeast
- Make up fungi
- Candida treatment?
- Pseudomonads treatment?
- Pertussis management for unvaccinated 1year baby (profen - azithromycin -
amoxicillin - dexamethasone)
- Pt has low TpmT which the effect with azathioprine--bone marrow suppression
- Treatment clostridium
- Plague transmited
- TB -TTT : ( 4MED )
- PT. with catheter jutter take : cipro
- pt. with pelyonephrities and -ve bacteria ttt?
- Pregnant take high dose ampicillin and after birth has high bilirubin what your
intervention : Ceftriaxone – genta – no antibiotic
-
-
- tuberculosis patient in ICU treatment?
a) Isolation
b) Treatment in icu then after stable treatment outpatient
c) Treatment in home
d) Hospital treatment without isolation
-
Natural products
- Ipecac
- St John's wort
- Ginko biloba
- نبته تستخدم للنقرس
- Enhance physical activity
- Enhance diabetic medication
8-2022 اختبارات
TAHANI
- Decrease TG level
- Use in dry cough
- Valrina uses
-
Genom
Economic
- +1
Statistic
Pain
Resource :
- 10page file
- Orion _ +1
- Ashwaq
- All non pharma
Threabutics
- Ulcerative colitis
- Case in ER Toxic symptom was constructe eye pupil ? ( atropine – physostigmen )
- Drug decrease MAC
- -Breast-feeding have tonic-clonic seizures
- Drug cause dry cough
- Drug cause constipation
- anti-anginal drug that cause dilatation of vascular smooth muscle
- which of the following describe nicardepine (ccb)
- drug contraindicated in diabetic pt. with CHF
- which cause peripheral edema
- - drug that cause sedation for fetus
- Dose vit A
- عالجTIA
8-2022 اختبارات
TAHANI
PHARMACOLOGY
- Methotrexate moa
- Isoniazid S.E
- Long insulin
- Time take aspart before meal ?
- Vit ci in pregnancy
- اختار عالجnarcotic
- Anesthesia iv ?
- Renin
- Less sadetive antihistamine
- What is the following predisposing to atherosclerosis (من ضمن الخيارات
hypothyroidism واخرتها
- Drug cause constipation (atorvastatin.verapamil.nitrate)
- Pt has muscle pain and dark stool the atorvastatin from the choices
- Moa flurouracil
- Case pt use adol + ibrufen → black stool : drug drug interaction – toxicity – gi
bleeding
-
- Pt with ischemic stroke when discharge from hospital must refer for which unit
(cardio – psychiatric – occupational )
- Pao2 in extracellular fluid (500.275-295 mm.hg/l/kgor 275-285mmole/l تقريبا
- Drug cause SJS TEN
- Pioglitazone : contraindication
- Non stimulant ADHD → atomoxifen
- Amitriptyline can cause : ( neuropathy – sedation – drowsiness )|
8-2022 اختبارات
TAHANI
c) Adult
d) Elderly
-
-
Cardio :
Pscy
LAB
- Dragondof test
GEN
- Ph رسمه
- COPE Limits
- رسمه الليثل دوز بس كان خط واحد
- snRNA function
- Ligase function
- Amylase function
- Flashing tables?
- Csf from which area
- Gluteal muscle volume of im inj
- Filtered syring in ampules. Vial..all iv prpn
- Variation in genes noticed with (frusemide. Opioid ....
- Labeling of controlled drug (C. N. O )
8-2022 اختبارات
TAHANI
CUTICS
Kin
Admn :
NON-PHARMA
communication :
8-2022 اختبارات
TAHANI
- Case about fresh pharmacist work in community pharmacy and customer ask why
cosmetics products is expensive then the pharmacist say because Our products are
good brand, not counterfeit what is type of communication
a) Assertive
b) Passive
c) Professional
d) Aggressiv
-
GEN2
الصيدالنية لما شافتhypothyroidsm and osteoprosis and DM مرأة كبيرة راحت للصيدلية معاها -
metformin and other drug for DM الملف لقت ان بس فيه
الخيارات
need more drug for other conditions -
non adherance -
there is schedule program for وحده جات الصيدليه تسأل من التطعيم لطفلتها واالجابه مفروض -
vaccination
من ضمن الخياراتcbahi في السعوديه وماكانتhealth accreditation مين المسؤول من ال -
-
8-2022 اختبارات
1-10 August 2022
Antidotes
**Copy/Pasted
Question Answer
Iron
Morphine
antidote of opioid
Antidote of dabegatran
Diazepam inactive
Heparin
Benzodiazepine
midazolam
Naloxone dose in paediatrics a) 2-4mg
b) 0.4-2mg
c) 0.5-2mg
Case in ER Toxic symptom was constructe eye Atropine
pupil Physostigmen
Morphine overdose doc: Naloxone
Antidote for vasopressor extravasation a) Atropine
b) Phentolamine
c) Vitamin K
Patient with mydriasis which antidote a) Flumazenil IV
b) Flumazenil IM
c) Naloxone 400mg IM
d) Naloxone 400ng IV
Paracetamol Acetylcysteine
Structures
**Copy/Pasted
Question Answer
Antimalaria
Selenium
Erythromycin
Vitamin D
Ergotamin
Acyclovir
Ethambutol
Barbiturates
Common pharmacophore
Lactone ring
Penicillin
Barbiturates ring
Conjugated amine
Analgesic for dysmenorrhea?Choose from
structure
Which part of structure bind to nicotine
receptor
Codeine → morphine
Phenytoin SAR
@beethepharmacist
1-10 August 2022
Photo oxidation
عالج يستخدم للزهايمر بس ممنوع عشانه يحتوي ع
امفيتامين
Ranitidine SAR
Structure of TCA the most effective one The choice are imipramine,cholormipramine
and the others are wrong structure
Structure of ethosuximide
Structures containing sulpha gr and choose
which one safe with sulphuric allergy
Bio isoster of indomethacin
Major metabolite of diclofenac
Structure of paracetamol c8h9no2
Advantage of pseudoephedrine over
ephedrine?
What we can to add on morphine structure to Add OH group at position 14
increase its activity?
physostigmine vs pyridostigmine structure and a) Continue physostigmine b/c
ask about replace pyridostigmine from the pyridostigmine can produce
formulary amphetamine
b) Replace to pyridostigmine b/c it can
produce amphetamine
c) Replace b/c pyridostigmine has lower SE
Calculations
**Copy/Pasted
Question Answer
Crcl
Ld
Absolute bioavailability
BMI
Calculate half life
Bioavailability equation
مل قطره عين٣ المسألة تبع كم عدد النقط في
Phenytoin 300mg in 10ml with conc 75g/ml and
diluted with D5%to 25mg/ml what is the conc of
both phenytoin and D5%
Vancomycin correction
10 ml ampoule of 3% drug how many mls 5ml
required to give 150mg dose?
50% alcohol is to be diluted with purified water, 30parts water + 20 parts 50% alcohol
how many parts of purified water (0% alcohol) to
prepare 20% preparation?
A dose for pt. is 75mg, how ml needed from a) 5 ml
125mg/5ml solution: b) 3 ml
c) 15 ml
If dose of drug is 0.2 mg, how many doses are in 75 doses
15ml:
How many gram of 5% ointment will be prepared 40mg
from 2mg:
@beethepharmacist
1-10 August 2022
TIAعالج
الرجال الي سافر ويبي مسيل دم
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1-10 August 2022
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1-10 August 2022
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1-10 August 2022
Biochemistry
**Copy/Pasted
Question Answer
How to activate trypsinogen to trypsin not pepsin?
Which correct a) Ergocalciferol is D3
b) Cholecalciferol is D2
c) Vit D 2 and D3 active biological
d) Vit D 2 and D3 inactive biological
↑ LP (alkaline phosphatase), ALT (alanine
transaminase), AST (aspartate aminotransferase), and
gamma-glutamyl tansferase (GGT)…what mean liver
dysfunction
Role of tetrahydrofolate Carbon transfer
Substrate renin a) Ang I
b) Ang II
c) Angiotensogmease
What is the role of coenzyme Q? a) Reduction of NAD to NADH
b) Oxidation of NAD to NADH
c) Oxidation of FADH2 to FAD
Reaction (NAD _ NADH+) give + 30 energy a) Exogenic
b) Endogenic
c) Endothermic
d) Exothermic
Women
**Copy/Pasted
Question Answer
Pregnant E.coli with G6PD
للحاملdomperidone اقصى مده تعطيه
Calcium elemental in pregnancy
Pregnancy category
HTN + PREGNANCY : SAFE AND HARM
Drug that cause sedation for fetus
Vit CI in pregnancy
@beethepharmacist
1-10 August 2022
more بفعل تكسر كريات الدم الحمراء وهذا باإلضافة يكونhemolytic anemia يسببG6PDالمختصر ان نقص ال
: القلق واألدوية مثل، مع بعض أنواع االكلtriggered
1. Hydroxychloroquine (RA treatment & Anti-malaria)
2. Sulfasalazine (RA treatment)
3. SMX/TMP (Antibiotic)
4. Primaquine (Anti-malaria)
5. Nitrofurantoin (used in UTI **mentioned before in urine discoloration)
!!!hemolysis risk ألن نخاف من الG6PD مع مرضى الCI عموما ً االدوية المذكورة ما نستخدمها
Pregnant women with UTI go عاديG6PD deficiency يعني ما عندها...إذا المرأة سليمة
ليش تكلمنا عن الحامل بالذات؟ الن الحامل معرضة with Nitrofurantoin
. خالل الحملpH اكثر بسبب اختالف الUTIلل الزم نبدل ال: مو عادي...G6PD deficiency إذا المرأة عندها
. ألنه آمن اكثرCefuroxime بNitrofurantoin
؟Nitrofurantoin عادي نعطيها...G6PD deficiency لو كانت المرأة مو حامل لكنها عندها
!contraindicated الاااا! احنا مو قلنا
Vitamins
**Copy/Pasted
Question Answer
Dose vit A
Biotin side effects
@beethepharmacist
1-10 August 2022
25-hydroxy-cholecalciferol
oxidized in the kidney to the active
form of vitamin D (1,25-Di-hydroxy-
cholecalciferol
@beethepharmacist
1-10 August 2022
Definitions
**Copy/Pasted
Question Answer
Privilege
Budget
Incident
Morbidity
Pharmacoepdemiology
Planning
Accounting
Incidence
Quarter tablet
Management
MIC
Accounting
HAM
Pharmaceutical psychology
Part describe job need
This called job description, job
advertisement
MTC mean: minimum safe conc OR Min. toxic conc.
MEC mean: minimum effective concentration
CMAX.: a. maximum conc. of the drug
to reach max effect
TMAX.: time required to reach max.
plasma conc
@beethepharmacist
1-10 August 2022
Study
**Copy/Pasted
Question Answer
4q
STUDY rear disease
Phase post market
Group of smokers and non-smokers , observe which
will develope lymphoma and which don't ... what's the
kind of study
Which type of data the researchers collect from a) Primary
patients direct? b) Secondary
c) Lab
Clinical pharmacist during the round they ask her to a) Expert opinion
choose one antibiotic for C.diff, and after searching she b) Cohort study
found that vancomycin orally bid is the best to choose, c) RCT
from where she conduct the information?
Primary information resources? a) Guidelines from CDC
b) RCT from PubMed
c) Handbook information
d) Review article
Communication/ Regulation
**Copy/Pasted
Question Answer
Assertive
Fresh pharmacist work in community pharmacy and a) Assertive
customer ask why cosmetics products is expensive b) Passive
then the pharmacist say because Our products are c) Professional
good brand, not counterfeit what is type of d) Aggressive
communication
يقول صيدالني توه متحرج وتوظف بصيدلية خاصة وش يسقط عنه
بالخيارات انه يصير يقدر يتعالج ببعض مستشفيات
جاني حقت الصيدلية اللي دخلت تهاوش اسعاركم غالية
وجاني اللي ما يتكلم غير هندي وش هنا ؟ ننادي زوجته تتفاهم معاه
مدير صيدليات في مكة وعدد من المدن وطلب صيدلي لفرع مكة ومن
ضمن أسئلة المقابلة كيف تساعد في زياده المبيعات او حاجه قريبه لكده
تقريبا
في السعودية وما كانتhealth accreditation مين المسؤول من ال
من ضمن الخياراتcbahi
diazepam مده صرف عالج
وش تحتاج معلومة عشان تعرف مدة صرف العالج
Responsible determine essential drug : moh – sfda
you are chief pharmacist ,when will you distribute a) After consulting with ethical
sample drugs to a hospital? committee
b) As per physicians order after
consulting with
c) Therapeutic committee
d) After consulting with pharmacy
supervisor
Service for geriatric patient with High risk Awlawia
@beethepharmacist
1-10 August 2022
Infection
**Copy/Pasted
Question Answer
MRSA
MSSA
What it have oral good activity cephalosporin?
Colostine high dose monitor?
methicillinالل اجابته
يsensitivity test سؤال ال
Encapsulated yeast
Make up fungi
Candida treatment
Pseudomonads treatment
Pertussis management for unvaccinated 1year baby a) Ibuprofen
b) Azithromycin
c) Amoxicillin
d) Dexamethasone
Pt has low TpmT which the effect with azathioprine--
bone marrow suppression
Treatment clostridium a) IV vancomycin
b) Oral metronidazole
Plague transmitted by a) House flies
b) Fleas
c) Mosquitoes
TB -TTT INH + rifambin + pyrazinamide +
ethambutol
PT. with catheter jutter take : Ciprofloxacin
PT. with pelyonephrities and -ve bacteria ttt?
Pregnant take high dose ampicillin and after birth has a) Ceftriaxone
high bilirubin what your intervention b) Gentamicin
c) No antibiotic
Tuberculosis patient in ICU treatment? a) Isolation
b) Treatment in ICU then after stable
treatment outpatient
c) Treatment in home
d) Hospital treatment without
isolation
Antifungal absorbed in low ph best recommendations take it in empty
Suitable Tetracycline for Renal impairment:
doxycycline
NOT fungus: E. coli
Bacteria move by Flagella
Which antiviral cause mitochondrial toxicity Stavudine 1 st OR zidovudine 2nd
Used for HIV&HIB Lamivudine
In HIV the CD4 less than 200
@beethepharmacist
1-10 August 2022
Natural products
**Copy/Pasted
Question Answer
Ipecac
St John's wort
Ginko biloba
نبته تستخدم للنقرس
Enhance physical activity
Enhance diabetic medication
Decrease TG level
Use in dry cough
Valerian uses
Dyslipidemia
**Copy/Pasted
Question Answer
What is the following predisposing to atherosclerosis واخترتهhypothyroidism من ضمن الخيارات
Hypothyroidism
Hyperthyroidism
Cushing syndrome
Peptic ulcer
Pt has muscle pain and dark stool the atorvastatin from
the choices
Niacin Has the Highest effect on HDL (the case with choices fenofibrate and niacin and
mild dyslipidemia and low HDL) others, I choose niacin
Simvastatin causes serious interaction with: Amiodaron
Which need to calculate CHA2DS2-VACS to calculate a) Patient with stroke
statin dose b) Patient with MI
c) Patient with DM
Which class from the following can cause diabetes Statin
ACEI
Statin taken at bed time
Least statin has drug drug interaction Simvastatin
Atorvastatin
@beethepharmacist
1-10 August 2022
Cancer
**Copy/Pasted
Question Answer
Methotrexate moa
Moa flurouracil
Genomics
**Copy/Pasted
Question Answer
CYP 2C19 Clopidogrel
Patient taking codeine and he is cyp2d6 poor Codeine overdose side effects
metabolizer Insuffincident relief of pain
https://www.ncbi.nlm.nih.gov/books/NBK100662/#!po=0.694444
The CYP450 enzymes are polymorphic, which means there are different forms of the same
enzyme; these polymorphisms may be responsible for much of the variability in medication
response
Clopidogre CYP2C19 Clopidogrel is a prodrug. It must be converted to Consider
its active metabolite by CYP2C19. alternative
The CYP2C19*1 allele is fully functional, whereas treatment
the *2 & *3 alleles indicate reduced metabolism
(less active metabolite formed).
Patients with CYP2C19*2 or *3 alleles are poor
metabolizers and have ↑ cardiovascular events
Codeine CYP2D6 Codeine is a prodrug & it’s metabolized to morphine Don’t use
via CYP2D6. Ultra-rapid metabolizers are at ↑ risk of (toxicity risk)
opioid overdose due to extensive conversion to
morphine.
Statistics
**Copy/Pasted
Question Answer
Patient 65kg Standard deviation 5 what mean a) Mean not less5
b) Mean not less10
c) mean not less20
d) Mean not less…..
Psychiatric
**Copy/Pasted
Question Answer
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1-10 August 2022
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1-10 August 2022
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1-10 August 2022
Which drug is high alert and should always be properly Epinephrine inj –EpiPen
labelled and separated
Infant with psoriasis Topical hydrocortisone
Oral hydrocortisone
@beethepharmacist
1-10 August 2022
HTN: RRAs-I, Beta blockers, CCBs, Diuretics, Centrally acting, Vasodilators, Pregnancy &
selection
**Copy/Pasted
Question Answer
Renin
Least to interact with b- blocker a) Phenytoin
@beethepharmacist
1-10 August 2022
b) Phenobarbital
c) Rifampin
d) Fluoxetine
CI of loop diuretic except: renal impairment
All of the following is the SE of thiazide diuretics expect a) Hypokalemia
b) Hyponatremia
c) Hypocalcemia
d) Hyperuricemia
Which true about dry cough with ACE inhibitors a) In women more than in men
b) It is mediated by bradykinin and
other mediators
c) Appear within 6 months of using
drug dose related
b blockers are used in all the following except: a) Migraine
b) Bronchial asthma
c) Hyperthyroidism
Patient with HTN, put on antihypertensive drug, after verapamil
few months developed heart failure, reduction in heart
rate, velocity, contraction:
Timolol CI expect: HTN
New Hypertensive pt Lisinopril
@beethepharmacist
1-10 August 2022
Endocrine
**Copy/Pasted
Question Answer
Long insulin
Time take aspart before meal?
Patient with HTN, DM, & MI which drug is CI Pioglitazone
Not use in decrease weight : levothyroxine
hypothyroidism, مرأة كبيرة راحت للصيدلية معاها a) need more drug for other
الصيدالنية لما شافت الملف لقت ان بسosteoporosis & DM conditions
metformin & other DM medication فيه b) non adherence
81yr old diabetic patient on oral hypoglycemics and a) Losartan
suffering from hypertension, which of the following b) Enalapril
antihypertensive drugs is not recommended: c) Hydrochlorothiazide
@beethepharmacist
1-10 August 2022
Pharmaceutics/ preparations
**Copy/Pasted
Question Answer
From powder to granulation
Advantages of IV route over oral route: a) Safe and convenient, rapid onset,
dose can be titrated, can be used
in ER
b) Rapid onset, can be used in ER
c) Safe and convenient, can be used
in ER
d) Rapid onset, dose can be titrated,
can be used in ER
Particle size affect which of the following: a) Uniformity
b) Homogeneity
c) Dissolution
Particle size affect the following: a) Solubility
b) Dissolution
c) Content-content uniformity
d) Suspendability
e) Penetrability
Emulsion inversion: conversion of W/O emulsion to O/w
emulsion and vice versa
Which is true about dry gum emulsion: a) Ratio 4:2
b) Gum and water are added
together and triturated then add
water at once
c) Gum and oil and water added
slowly
d) None of the above
@beethepharmacist
1-10 August 2022
Foam in pharmacy found as spray is used as: a) Burn dressing and topical but not
for rectal administration
b) Topical and rectal but not for
burns
c) Topical, rectal and for burn
dressing
Conductivity test – Dilution test – Dye test used for Susp. Emulsion
which dosage form:
If an emulsion is able to conduct electricity then the a) Aqueous
dispersion phase is probably: b) Non-Aqueous
c) Low-lipophilic
d) Hydrophilic
GEN
**Copy/Pasted
Ph رسمه
- COPE Limits
- رسمه الليثل دوز بس كان خط واحد
- snRNA function
- Ligase function
- Amylase function
- Flashing tables?
- Csf from which area
- Gluteal muscle volume of im inj
- Filtered syring in ampules. Vial..all iv prpn
- Variation in genes noticed with (frusemide. Opioid ....
- Labeling of controlled drug (C. N. O )
High risk – low risk – intermediate ( ) ملف شيماء
- Pt. remain in TPN 6month will cause : (CKD – Acid-base imbalance – bone disease)
- Pt. visit doctor after that have appointment after 3 month -→ form SOAP → (PLAN -ASSMENT
– OBJECTIVE – SUBJECTIVE )
- No current disease : incidence – prevalence – morbidity – mortality )
- sterile water for injection is : pyrogen less than 1000/ml
- double check mean
a) 2 professional check dependently
b) 2 professional check independently
@beethepharmacist
1-10 August 2022
Natural products
Recurrent UTI Cranberry juice
BPH (benign prostatic hypertrophy) Saw palmetto
Se: dizziness, headache, n/v/c/d.
Painful menstruation & hot flashes Black cohosh
**Estrogen-like
Don’t use it with amiodarone Grapefruit
Herbal safe with warfare Fish oil
Dry cough Thyme
Cough relief Ivy plant
Oil form eucalyptus tree
Stress Chamomile, lavender, lemon
Herbal for mental disease Ginkgo biloba
Used in Alzheimer **Increase cerebral blood flow
Herbal for sedative Valerian
Increase physical activity Ginger
Flavour used in medications Fruits
Natural products of burning Running water, Aloe Vera, honey , coconut oil,
vinegar
Silver sulfadiazine FDA approved for wound
infection and burn
To treat vomiting Ginger
Citrus lemon, berberis vulgaris, malus domestica,
mentha piperita, valeriana officinalis, zingiber
officinalis
Natural products for hyperlipidemia Garlic, red yeast rice, Fish oil
Plant with adaptogenic effect Ginger, Chinese Schisandra
Plant source use for acute gout Colchicine
Derived of belladonna Atropine
Chondroitin/ glucosamine Osteoarithritis
Melatonin Sleep regulation for people work with different
shifts
St. John's wort Anxiety & depression
CYP inducer
Co-enzyme Q10 ↓myopathy when co-administer with STATINS
Anti-malaria from natural source Cinchona “quinine”
Plant sources of anticancer Vinca Alkaloid: Vinblastine, Vincristine,
Vindesine, Vinorelbine
**Vincristine Fatal if given intrathecal ONLY IV
infusion
Texans: Paclitaxel, Docetaxel
Plant origin (epipodophyllotoxin): Etoposide
Natural estrogen Estrone, Estriol, Estradiol
Sources of insulin Human insulin → E.coli by DNA technology
Cows
Pigs
Human
Natural emulsifying agent Acacia
Decoction: Is a method of extraction by boiling herbal or plant material to dissolve the
chemicals of the material.
@beethepharmacist
1-10 August 2022
يعني نفس لما نغلي شي وبعدين نشرب الماي ماله..**بالعربي ترجمتها االستخالص بالغليان
Incr. (↑) INR (bleeding risk) Dec. (↓) INR (clotting risk)
Natural Cranberry, Chinese Angelica, Ginger, Soya, St John’s Wort, Green tea,
products Grapefruit, Garlic, Ginseng, Ginkgo Vitamin E, Co-enzyme Q10
Vitamins
Fat soluble vitamins (ADEK)
Lipid vitamins are important for liver
Vit Name Uses/ notes Deficiency
A Retinol Antioxidant Night blindness
High doses (>15000 IU) is CI in
pregnant woman
D3 Cholecalciferol Needed to absorb Ca → bone Children→ Rickets
growth Adults→ Osteomalacia
CKD→ ↓PTH ↑ risk of CVD
↓Breast cancer risk
Used with patient using
corticosteroids for 6 months
E Tocopherol, Antioxidant
alpha-tocopherol Fertility→ used in infertility
cases
K Phylloquinone **Remember WARfarin is a vitamin Bleeding
K antagonist
Water soluble vitamins (B&C)
B1 Thiamine Beriberi
B2 Riboflavin Ariboflavinosis
@beethepharmacist
1-10 August 2022
@beethepharmacist
WEEK : 1 WEEK : 2 WEEK 1+2 : ++ TAHANI
- Iron
- Morphine
- opioid
- dabigatran : darucizumab ++
- Antidote heparin : protamine sulphate ++
- Enoxaparin : protamine sulphate
- Benzodiazepine ++
- Midazolam
- Diazepam inactive
-
- Mydriasis antidote : flumazil IV - IM – Naloxone IV – IM )
- NALOAXONE dose in pedia
- Digoxin
- Lithium
- Methaglubilinemia
- Organophosphates
- Acetaminophen antidote? Acetylcysteine
Structure :
- Antimalaria ++++
- Quinine and asked what is the action of it if converted to quinidine
-
- Selenium
- Erythromycin
- Ergotamin
- Acyclovir
- Ethambutol
- Barbiturates
- common pharmacophoreبيقولي
- lactone ring I think
- Barbiturates ring
- conjugated amine
- analgesic for dysmenorrhea? choose from structure
- which part of structure bind to nicotin receptor
- codeine → morphine ( )او العكس++
- Phenytoin SAR
- Photo oxidation ++
- عالج يستخدم للزهايمر بس ممنوع عشانه يحتوي ع امفيتامين
- Ranitidine SAR
- Structure of TCA the most effective one the choice are imipramine ,cholormipramine
and the others are wrong structure ++
- Structure of ethosuximide
- Ethosuximide : Enatrizomer ??
- Structures containing sulpha gr and choose which one safe with sulphuric allergy
- Bio isoster of indomethacin
- Major metabolite of diclofenac ++
- Structure of paracetamol c8h9no2
- advantage od pseudoephedrine over ephedrine?
- What we can to add on morphine structure to increase its activity? Add OH group at
position 14
- physostigmine vs pyridostigmine structure and ask about replace pyridostigmine
from the formulary ++
a) continue physostigmine b/c pyridostigmine can produce amphetamine
b) Replace to pyridostigmine b/c it can produce amphetamine
c) Replace b/c pyridostigmine has lower SE
- NO of tabs 3 questions
- structures of cephalosporins asked which one is oral
- acetyl choline What function group binding with receptor
- levothyroxine
- NSAIDs
- Oseltamivir
- Aspirin
- Fondaparinux
- Azoles
- How Methicillin penicillin resistance
- Amphotericin B (hydrolysis)
- Paracetamol (h-bond)
- Sulphonylurea
Calculation :
- Crcl ++++++++
- Ld ++
- Absolute bioavailability ++++
- BMI ++++
- calculate half life
- Bioavailability equation ++++
- Cl equation
- مل قطره عين٣ المسأله تبع كم عدد النقط في
- Dose that give conc at 4hr (vd and Kel just are given)
- Phenytoin 300mg in 10ml with conc 75g/ml and diluted with D5%to 25mg/ml what
is the conc of both phenytoin and D5%
- Vancomycin correction
- Osmolarity : ++
- Clearance : ++
- Clearance → cl= elimination /dose
- Rate of administration 4 questions ++
- Tmax
- Relation between T1/2 and css
- Phenytoin corrections
- Elimination rate
Anticoagulant + antiplatelet :
- More
- Vitamin k and
- warfarin
- anticoagulants used after food : rivaroxaban ++
- Anticoagulant for pregnant
- +1
- Antiplatelet CI in TIA ++
- Chadsvasc score for 60year htn and dm
- atrial fibrillation patient with a CHA2DS2-VACS score of 2 ??? man or women
- INR range Mittral valve
- INR DVT
- Vegan diet and INR ( Increase – decrease – no change IN INR )
- Extrinsic pathway in clotting occure by : tissue trauma
- Monitoring enoxaparin : Xa factor ??
Immunity :
- iGg
- iGm
- iGe
- NK cell function
- Ig found in colestrim
- Hypersensitivity reaction type II ? IgG - IgE - IgM – IgA
- Dominate : IgG
Bioche:
vomiting
- Ginger ++
- vitamin b6
vaccine
- vaccine and dental work what is type of demand : positive, negative , may be latent
- Vaccin : orally or im ( polo – varella – mmr )
- Herps simple box : varicella vaccine
- Vaccine give between 6-12 month :
Women
Definition:
- Privilege
- Budget
- Incident
- Morbidity
- Pharmacoepdemiology
- Planning
- Accounting
- Incidence
- Quarter tablet Definition
- Management
- MIC
- Accouting
- HAM
- Pharmaceutical psuchology
- 4 principles of bio-ethics:
- justice5 +
- DM : incidence – prevalence
- What sterile vail, ampule …
- Pharmacovigilance
- Flash tab : fast release
- Bioavailability
Study :
- 4q
- STUDY rear disease
- Phase post market
- group of smokers and non smokers , observe which will develope lymphoma and
which don't ... what's the kind of study
- which type of data the researchers collect from patients direct? (primary, 2ed , lab)
- clinical pharmacist during the round they ask her to choose one antibiotic for
C.diff,and after searching she found that vancomycin orally bid is the best to choose
,from where she conduct the information?
a) -expert opinion
b) -cohort study
c) -rct not su
-
- primary information resources?
a) GUIDELINES FROM CDC
b) RCT FROM PubMed
c) handbook information
d) Review article
- The most reliable study to make a clinical decision? Systematic review - Case
control Cohort study
- doctor noticed a new side effect for a drug, what study should he wrote? Case
control - Clinical trial
- deemed trail : ethical approval
- small number Patient : phase II
- risk ratio equation : or for what :
Communication
- assertive ++
infectious:
- Mrsa
- Mssa
- What it have oral good activity cephalosporin ?
- Colostine high dose monitor ?
- سؤال الsensitivity test اللي اجابتهmethicillin
- encapsulated yeast
- Make up fungi
- Candida treatment?
- Pseudomonads treatment?
- Pertussis management for unvaccinated 1year baby (profen - azithromycin -
amoxicillin - dexamethasone)
- Pt has low TpmT which the effect with azathioprine--bone marrow suppression
- Treatment clostridium
- Plague transmitted
- TB -TTT : ( 4MED ) ++++
- PT. with catheter jutter take : cipro ++++
- infective endocarditis Culture show staph sensitive to linezolid but linezolid not
approved by FDA for infective endocarditis So what to do.
a. Give vancomycin
b. Don't give linezolid
c. Give linezolid as off label
- Vit c used to decrease
a. viral infection severity
b. Viral infection duration
- which vitamin used to decrease flu infection duration : ( vit C – D- Ca++ - folic acid )
- sore throat : Hemophilus influnza - Mycobacterium tuberculosis
- NOT effective for the treatment of P.aeruginosa UTI ? (TMP/SMX – Ciprofloxacin –
Methenamine – Norfloxacine )
- nose congestion + cough: Diphenhydramine
- Rifampicin counseling points?
- Virus cell contain? Plasmid – Peptidoglycan
- Antiviral +pneumonia : oseltamivir
- HIV + Pregnancy : zidovudine
- HIV : CD4
Natural products
- Ipecac
- St John's wort
- Ginko biloba
- نبته تستخدم للنقرس
- Enhance physical activity
- Enhance diabetic medication
- Decrease TG level
- Use in dry cough
- Valrina uses
- Source digoxin : foxglove
- Source warfarin : coumarin
- Amebiasis: Ipecac
Genom
Economic
- +1
- Cost drug same generic name
Statistic
Pain
SAFTY:
Resource :
- 10page file
- Orion _ +1
- Ashwaq
- All non pharma
Threabutics
- Ulcerative colitis
- Case in ER Toxic symptom was constructe eye pupil ? ( atropine – physostigmen )
- Drug decrease MAC
- -Breast-feeding have tonic-clonic seizures
- Drug cause dry cough
- Drug cause constipation
- anti-anginal drug that cause dilatation of vascular smooth muscle
- which of the following describe nicardepine (ccb)
- drug contraindicated in diabetic pt. with CHF
- which cause peripheral edema
- - drug that cause sedation for fetus
- Dose vit A
- عالجTIA
PHARMACOLOGY
- Methotrexate moa
- Isoniazid S.E
- Long insulin
- Time take aspart before meal ?
- Vit CI in pregnancy
- اختار عالجnarcotic
- Anesthesia iv ?
- Renin
- Less sadetive antihistamine
- What is the following predisposing to atherosclerosis (من ضمن الخيارات
hypothyroidism واخرتها
- Drug cause constipation (atorvastatin.verapamil.nitrate)
- Pt has muscle pain and dark stool the atorvastatin from the choices
- Moa flurouracil
- Case pt use adol + ibrufen → black stool : drug drug interaction – toxicity – gi
bleeding
-
- Pt with ischemic stroke when discharge from hospital must refer for which unit
(cardio – psychiatric – occupational )
- Pao2 in extracellular fluid (500.275-295 mm.hg/l/kgor 275-285mmole/l تقريبا
- Drug cause SJS TEN
- Pioglitazone : contraindication
- Non stimulant ADHD → atomoxifen
- Amitriptyline can cause : ( neuropathy – sedation – drowsiness )|
- Alzheimer : Donepezil
- Increase absorption iron : vit C
- Ca++ dose in elderly pt. : 1200mg ?
- Interaction theophylline + smoking : increase dose
- Posterior pituitary gland : antidiuretic hormone ( ADH )
- CI in osteoarthritis : cortisone
- Dry cough ttt :
- Tow agent cause hepatotoxic : aminoglycoside + furosemide ????
Cardio :
Pscy
LAB
- Dragondof test
- Statin : creatin kinase
- Estimate renal function : CrCL
- Warfarin: gum bleeding
GEN
- Ph رسمه
- COPE Limits
- رسمه الليثل دوز بس كان خط واحد
- snRNA function
- Ligase function
- Amylase function
- Flashing tables?
- Csf from which area
- Gluteal muscle volume of im inj
- Filtered syring in ampules. Vial..all iv prpn
- Variation in genes noticed with (frusemide. Opioid ....
- Labeling of controlled drug (C. N. O )
- TB patient in ER and Discharge ?????
a) give anti TB and Discharge
b) he is now not contaginous so keep pt in ER until stabilizing then go home
c) hospitilaize with no isolation
d) hospitilize without isolation
CUTICS
Kin
Admn :
NON-PHARMA
communication :
- Case about fresh pharmacist work in community pharmacy and customer ask why
cosmetics products is expensive then the pharmacist say because Our products are
good brand, not counterfeit what is type of communication
a) Assertive
b) Passive
c) Professional
d) Aggressiv
-
GEN2
مرأة كبيرة راحت للصيدلية معاها hypothyroidsm and osteoprosis and DMالصيدالنية لما شافت -
الملف لقت ان بس فيه metformin and other drug for DM
الخيارات
need more drug for other conditions -
non adherance -
يقول صيدالني توه متحرج وتوظف بصيدلية خاصة وش يسقط عنه -
بالخيارات انه يصير يقدر يتعالج ببعض مستشفيات
-
جاني حقت الصيدلية اللي دخلت تهاوش اسعاركم غالية -
وجاني اللي ما يتكلم غير هندي وش هنا ؟ ننادي زوجته تتفاهم معاه -
مدير صيدليات في مكه وعدد من المدن وطلب صيدلي لفرع مكه ومن ضمن اسئله المقابلة كيف تساعد في -
زياده المبيعات او حاجه قريبه لكده تقريبا
Part describe job need............ -
This called job description, job advertisement -
وحده جات الصيدليه تسأل من التطعيم لطفلتها واالجابه مفروض there is schedule program for -
vaccination
مين المسؤول من ال health accreditationفي السعوديه وماكانت cbahiمن ضمن الخيارات -
)Amphetamines (pyrdostgminانه اكتشفو منه دواء تاني ودايرين يقرروا بالمستشفى انه يستخدميه وال -
ال