ETIOLOGY:

PREDISPOSING FACTOR: UNKNOWN PRECIPITATING FACTOR:

 Pregnant women  Nutritional Deficiency (Low

 Extremes of age (<20 and >35) protein intake, beta carotene,
- 42 years old Folic Acid, and animal fat diet)
 Asian heritage  Gene mutation
 History of molar pregnancy  Artificial insemination
 Usage of Oral contraceptive pills

Sexual Intercourse

Abnormal process of fertilization

PARTIAL MOLE COMPLETE MOLE

COMPLETE MOLE

DUPLICATION

Implantation of Blastocyst


Abnormal proliferation of Trophoblast

(Partial) (Complete) Rapid Growth of Abdominal

uterus Pain
SOME ALL
Trophoblastic Trophoblastic
villi forms Villi swell and High HCG High TSH High Progesterone
normally become cystic (Tyrotrophin)

Nausea/ Hyperthyroidi Relaxation of

Edematous vomiting uterine muscle
sm
Syncytiotropoblas placenta
Trophoblast Separation of
tic layer of villi
Grape-like becomes mole vesicles from
becomes swollen
vesicles (fluid uterine wall
and misshapen

Vaginal
Embryonic Choriocarcinoma
Trophoblast death at only 1- Bleeding
becomes mole 2 mm in size
Blood loss
Pallor Anemia
Embryo grows for
9 weeks then Dizziness hypoxemia
macerates Fatigue

Embryonic death