LC 6000

HIGH PERFORMANCE LIQUID

CHROMATOGRAPH
SCION Instruments brings Performance, Functionality and
Reliability together into its impressive 6000 Series HPLC product
line up, making it the chromatographer’s choice in HPLC.
LeC6000
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Outstanding Performance for Confident Results
THE SCION 6000 SERIES HPLC AIMS FOR
CONFIDENCE IN RESULTS THROUGH
OUTSTANDING LIFE-TIME PERFORMANCE.
A robust design maximises uptime and
productivity levels whilst minimises cost
of operation.
The SCION 6000 Series offers an array of
automation options for workflow optimisation,
making our lab experience the best and
easiest possible.
Key Values
Superior gradient performance and
excellent flow rate precision
The SCION 6100 Quaternary pump has a new
low-pressure mode called High Frequent Mode
(HFM), which utilises a double switching function
of proportioning valves. HFM with the high-speed
real-time feedback control system greatly suppresses
liquid pulsation for superior reproducibility of gradient
and retention times.
Excellent injection volume precision and
ultra-low carry-over
The newly adopted high-precision syringe drive unit
provides excellent injection volume precision. Dead
volume in the SCION 6210 Autosampler flow path has
been minimised. Together with a pumping method
that washes the needle outer wall, this has resulted in
a superior precision autosampler with extremely low
carry-over. A thermostat option is available to maintain
sample temperature between ambient -21°C and
ambient +25°C, to prevent crystallisation of sample
components in the vial, thus ensuring sample integrity.
Best Chromatography
The SCION 6310/6320 Column Oven delivers accurate
Peltier-based heating cooling profiles, delivering sharp
peaks with excellent peak symmetry. The column oven
accommodates three 300 mm ID-tagged analytical
columns fitted with a guard-column.
Excellent Detector Performance
The 6000 Series HPLC line-up comes with a portfolio
of detectors including UV and DAD, all designed for
stability, precision and sensitivity.
SCION Instruments
Reliability & Efficiency in one solution
Instrument robustness
SCION 6000 Series HPLC is made for robustness and best
return on investment (ROI). Covers are made of heat-resistant,
chemical-tolerant, and UV irradiation-withstanding materials.
The internal walls of the modules are made with corrosion
resistant material to cope with humidity and vaporisation of
solvents. The column oven incorporates a solvent leak sensor
and a gas sensor to spot leaks. A door lock mechanism and
auto power-off/function-on lamp replacement further add
to robustness.
Compass CDS Control
The SCION 6000 Series HPLC offers complete support through
CompassCDS, adding full instrument control & automation, a
complete suite of integration, calibration and reporting tools,
and allowing for full 21CFR11 compliance.
Low volume Degassing options
To avoid any salt precipitation from the mobile phase, the
SCION 6000 Series HPLC includes an auto plunger washing
mechanism that prevents damage to the pump seal or the
plunger. The low-volume degassing unit reduces solvent
purging time and reduces the amount of solvent used.
Extra Large Solvent cabinet
The SCION 6510 Organiser is designed for multiple-liquid
operation and can hold different bottle sizes to accommodate
these typical applications.
∙ Six-channel degassing unit
(480 μL/ch) (optional)
∙ Auto-purge valve (Pumps
with or without Auto-purge
valve are available)
∙ Conventional mixer
(Accessory of the low-
pressure gradient unit option)
∙ Plunger washing pump
(optional)
 Scion Instruments

SCION 6000 Series HPLC

Configuration Modules

6510 ORGANISER (SOLVENT CABINET)

6100 QUATERNARY PUMP

6210 AUTOSAMPLER
6220 AUTOSAMPLER WITH COOLING UNIT

6310 COLUMN OVEN

6320 COLUMN OVEN (WITH PELTIER)

6430 DIODE ARRAY DETECTOR

6410 ULTRAVIOLET DETECTOR

scioninstruments.com SCION Instruments SCION Instruments NL BV

Tel: +44 (0)1506 300200 HQ, Livingston Business Centre, Amundsenweg 22-24,
Email: sales-eu@scioninstruments.com Kirkton South Road, West Lothian, 4462 GP Goes,
EH54 7FA, Livingston, United Kingdom Netherlands

For research use only. Not for use in diagnostic procedures. ©SCION Instruments 2020
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6100
Solvent Deliver System

Physical Specifications
Type Specification

Dimensions 440×340×140 （mm）

Weight 16kg

Power 24V DC , 4.0(max), 96W

Communication E-line (RS242)

Performance Specifications
Type Specification

Pulse Real time feedback system

60 Mpa (0.001~2.500 mL/min)

Pressure
30 Mpa (2.500~5.000 mL/min)

Pressure setting range 0.0~60.0 Mpa

Flow rate setting range 0.001~5.000 mL/min

Recommanded flow range 0.010~2.500 mL/min

Constant ambient temperature of 20° C, Distilled water, Solvent

delivery pressure 30 Mpa:
Flow rate accuracy
±2 μL (0.010 - 0.100 mL/min)
±1% (0.101 - 2.500 mL/min)

Flow rate precision RSD <0.05%

Pressre accuracy ±5%

Stainless steel 316, ruby, sapphire, zirconia, PTFE, Carbon PTFE,
Wetted Material
PEEK, Vespel®

LC 6000
Low Pressure Gradient Unit Dynamic Mixer
Type Specification Type Specification

Gradient profile Liner, stepwise Max. pressure 40Mpa

Gradient precision 0.15% Mixer volume 2000μL

Settable mixing ratio 0~100% 1% step Mixture method Stirring bar

Gradient accuracy Recommanded flow

<2.0mL/min
rate
0,5%

Recommended flow 0.4 – 1.8 mL/min (with conventional mixer)

（
）
range < 0.4 mL/min (with semi micro mixer)

Program number 9

Program time 600min (Max) Conventional Mixer

1. Time; 2. Flow Rate; 3.Mixing Ratio; 4.Event Type Specification
Time output; 5. Stopping of solvent delivery;
Max. pressure 60Mpa
Program items
6. Buzzer
Mixer volume 700μL

Recommanded flow
0.4~1.8mL/min
rate

Six-channel Degassing Unit

Type Specification

Channels 6 (Pump: 4 paths; Autosampler: 2 paths) Semi-micro Mixer

Max. flow rate 5mL/min Type Specification

Recommended flow Max. pressure 60Mpa

<3mL/min
rate
Mixer volume 200μL
Chamber volume 510μL
Recommanded flow
<0.4mL/min
Wetted materials Teflon® AF、PEEK、FEP、PPS rate

Plunger Wash Pump

Type Specification

Flow rate 1mL/min

Solvent Distalled water only

Max. pressure 65Kpa

TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6210/6220
Autosampler

Physical Specifications Performance Specifications

Type Specification Type Specification
Dimensions 520×340×320 (mm)
200 (1.5 mL)
Weight 23kg/26kg (Thermo unit) 28 (4mL) (option)
Standard samples
288 (96-hole microplate) (option)
Power 24V DC , 2.1A 1152 (384-hole microplate) (option)

Communication E-line (RS242) Injection method Direct injection

Max. pressure 60.0 Mpa

100 μL (standard)
Syringe volume
500 μL, 1 mL, 2.5 mL (option)

Injection volume precision < 0.3 % RSD (in 10 μL injection)

Injection volume accuracy ±0.8% (50μL, n=10)

Injection linearity R2 = 0.999

< 0.003 % RSD (with 10 μL of blank solution

Carryover injected after 10 μL of 60 mg/100 mL
methylparaben)

Injections per sample 99max

Maximum cycle time 999min

Thermo Unit (optional-6220)

Type Specification

Temp. setting range 1 to 35 ºC (settable in 1 ºC steps)

Cooling power 4 to (room temperature - 5)ºC

Cooling system Thermoelectronic system with Peltier element

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6310
Column Oven

Physical Specifications
Type Specification

Dimensions 360×490.5×174 （mm）

Weight 13kg

Power AC100 to 240V (50/60Hz)

Communication CAN

Performance Specifications
Type Specification

Column size and capacity 250mm × 3pcs column

Temp. control method Peltier heating / forced-air cirulation

Temp. setting range 1~85­°C

Temp. control precision ±0.5°C

Temp. stability ±0.1°C

Operation temp. range 4~35­°C

Safety measures Temperature fuse, solvent sensor adn temperature upper limit

Optional Switching valve

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6410
Ultraviolet Detector

Physical Specifications
Type Specification

Dimensions 490×360×174 (mm)

Weight 14kg

Power 24V DC , 2.5A (MAX) / 60W

Communication CAN

Performance Specifications
Type Specification

Light source Deuterium (D2) lamp

Wavelength 190~600nm

Bandwith / Slit width 8nm

Wavelength accuracy ±2nm

Noise < 1×10-5 AU

Drift < 2.5×10-5 AU/h

Offset 0~2 AU (0.001step)

Cell capacity 12μL

Cell pressure 0.1Mpa

Acquisition rate 0.5, 1, 10, 20 Hz

Maximum 50 steps
Time program
Maximum 600 min in steps of 0.1 min

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6430
Diode Array Detector

Physical Specifications
Type Specification

Dimensions 440×340×140 (mm)

Weight 14kg

Power 24V DC , 3.5A (MAX) / 84W

Communication E-line (RS242)、USB 2.0

Performance Specifications
Type Specification

Diode elements 1024-bit photodiode array

Light source D2 lamp, W lamp, Hg lamp (for wavelength check)

190 to 900 nm (D2&W mode)

Wavelength range 190 to 400 nm (D2 mode)
401 to 900 nm (W mode)

Wavelength accuracy ＜ ±1nm

Slit width 1nm(fine), 4nm(coarse)

Response 0.01, 0.02, 0.05, 0.1, 0.5, 1.0, 2.0 secs. in steps of 7

＜ 0.5 × 10 AU
-5
Noise

＜ 0.4×10 AU/h
-3
Drift

Offset 0~2 AU, 0.001 step

Cell capacity 13μL

Cell pressure 14.7Mpa

Thermo cell temp. control 40 °C, fixed (operation temperature range: 4 to 30 °C)

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6440
Fluorescence Detector

Physical Specifications
Type Specification

Dimensions 440×340×280 (mm)

Weight 25kg

Power AC 100 to 240 V (50/60 Hz) / 330VA

Communication E-line(RS242), USB 2.0

Performance Specifications
Type Specification

Light source Xe lamp, Hg lamp (for wavelength check)

Ex wavelength range 200~850nm

Em wavelength range 190~900nm

Ex bandwidth 15nm

Em bandwidth 15nm, 30nm(selectable)

Wavelength accuracy ＜ ±3nm

Wavelength precision ±0.5nm

Response 0.01, 0.02, 0.05, 0.1, 0.5, 1.0, 2.0 seconds

Sensitivity Water Raman peak S/N 3000 (Specified conditions)

Cell 12μL, 1.0 Mpa

Cell temp. control (optional) 40 °C, Fixed (Operation temperature range :4 to 30 °C)

Time programs 9steps, up to 600mins

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

SCION 6460
Refractor Index Detector

Physical Specifications
Type Specification

Dimensions 440×340×140 （mm）

Weight 12kg

Power AC 100 ~ 240V±10%, 50/60Hz, 150VA

Communication USB 2.0

Performance Specifications
Type Specification

Flow cell type 2 chamber-type

Measuring method Deflection type

Refractive Index range 1.00 to 1.75

Measuring range 0.25 to 512μRIU

Drift 0.2μRIU/h (Pure water 1mL/min, PURGE OFF)

Linearity range ≥600μRIU

Noise ≤2.5nRIU (Pure water, response : 1.5sec)

Response 0.1 , 0.25 , 0.5 , 1 , 1.5 , 2 , 3 , 6 sec

Cell volume 8μL

Max. back pressure 50kPa

Usual: 0.2 to 3.0mL/min
Flow rate
Max.: 10mL/min (solvent: pure water)
Temp. control OFF, 30 to 50°C (1°C step), 77°C Temp. fuse

Local control CompassCDS

LC 6000
TECHCOMP Instrument LTD.

SCION LC6000 Specifcations

High-Performance Liquid Chromatograph

Column Switching Valve

2-Position, 6-Port

Specifications
Type Specification

Port Size Accepts 10-32 male threaded fittings

Flow Passage Diameters Stator- 0.3-mm (0.012”), Rotor Seal- 0.25-mm (0.010”).

Port to Port Volume 450nL

Maximum Pressure 41 MPa (414 bar, 6000 psi).

Motor 5 ohm, spark-free, 7.5 degree stepper motor

Actuation Time 100ms

Communication 1-Line Level Logic

Power Requirements 24 VDC ± 5% at 1 Amp max

Quiescent Current 20mA

RoHS Compliant Yes

LC 6000
LC6000

Specification sheet

SCION 6510 Organiser

(Solvent Cabinet)
Dimensions & Weights
Dimensions: 340W x 420D x 200H (mm)

Weight : 9 kg

Output Power
One pump

One autosampler

Two detectors (UV, UV-Vis, Diode Array or RI)

One interface control board

Power Supply/ Consumption: AC 100 V to 240 V (50/60 Hz), 520 VA

Bottle Capacity
Extra-large solvent cabinet

6 x 1 L bottles and 3 x 500 mL bottle

SCION Instruments HQ SCION Instruments NL BV

Suite 34, Livingston Business Centre Amundsenweg 22-24,
Kirkton Road South, Livingston, 4462 GP Goes,
EH54 7FA, Scotland, UK. The Netherlands
Tel: +44 1506 300 200 Tel: +31 (0) 113-287 600
sales-eu@scioninstruments.com sales-eu@scioninstruments.com
www.scioninstruments.com www.scioninstruments.com
Chromatography Data System
Single Platform - Simply Powerful
CompassCDS is SCION Instruments’ universal Chromatography Data System designed for instrument control, data
acquisition, processing and reporting. With its unique capacity for customization, CompassCDS provides users with
a powerful data analysis tool with comprehensive calibration and calculation options. Originating from the legacy
Galaxie CDS, CompassCDS has evolved into the next generation CDS which easily integrates with LIMS, PCS/SCADA,
ERP and other commonly used data management systems.

The CompassCDS operator-friendly and intuitive graphical user interface (GUI) has been designed to improve the
operator experience by streamlining workflows thereby increasing sample throughput and overall productivity.
The Dual View function, when used in conjunction with the InstantView option, enables users to run samples, view
live data acquisition and review and report results from a single screen without the need to retrieve any data files.
CompassCDS also comes standard with the feature set required to support laboratories that are required to comply
with 21CFR11 and ISO/IEC 17025, and others.
Plug-in Flexibility
CompassCDS provides users with one of the most ChromSync
powerful chromatography data management solutions ChromSync is a post-run plug-in, initially developed for
available today. However, there are often application- the flavor and fragrance industry, that automates the
specific instances that require additional flexibility and manual task of comparing complex chromatograms
for these, CompassCDS has a comprehensive and well against reference standard runs. The ChromSync peak
documented API that enables the development of custom matching algorithm accommodates significant peak
pre- and post-run plug-ins. Examples of the many plug-ins distortion and retention time shifts. Area % comparison
currently available include: of matched peaks are compared against predefined
tolerance limits to provide an overall degree of similarity
1-Button interface and color coded pass/fail reports are generated.
The 1-Button interface, was developed for plant
operators to be able to run samples and when necessary
recalibrate as single icon clicks without having to access
the CompassCDS application. This pre-run plug- in can
also be set to continuously sample product streams
24/7 when not being used to run operator samples.

Hydrocarbon Reporting Tool

The Hydrocarbon Reporting Tool is a user customizable
post-run plug-in that per- forms GPA/ISO and ASTM
calculations on gas samples from single to multi-channel
analyzers and ….produces custom reports in PDF, CSV and
XML format for data exchange with LIMS and ERP.
Scalable Solution

CompassCDS can be installed as a simple, single

PC workstation application controlling a couple of
instruments through to a multi-lab, multi-vendor and
multi-instrument networked enterprise client/server
solution and anything in between. When deployed as a
client/server system, CompassCDS can be installed in a
number of configurations that conform with the current
networking and operating system architectures including
classic “fat” client, metaframe “thin client” and virtualized
environments, and in certain instances, combinations of
these. The CompassCDS unique acquisition and control
architecture can be centralized on the main server or
distributed among several acquisition servers/PCs and
should a computer controlling the instruments fail, the
ownership and subsequent control of those instruments
can be quickly transferred to another PC with a few
mouse clicks.

Secure, Centralized Administration

Using the separate and secure Configuration Manager,
system administrators can build their own customized
CompassCDS structure, in terms of groups, projects, data
storage paths, users, user access profiles, instruments,
regulatory compliance and overall system security
policies, from any CompassCDS computer on the network.
Configuration Manager settings are invisible to
CompassCDS users while all of their actions including
logon/logoff, run starts and stops etc. are monitored
and recorded in archivable audit logs in compliance with
21CRF11.
Complete Control
CompassCDS has an ever-expanding suite of instrument Redundant Data Storage
control drivers that enable users to operate any number
of chromato- graphic systems from any computer. CompassCDS makes use of an All-In-One flat file as the
Currently the CompassCDS control driver selection default data storage format. These .DATA files store all raw
includes: data points, a “live” copy of the method used to acquire
and process the data, all results including any custom
calculations and associated equations, all additional
• SCION 436 and 456 GCs and Analyzers metadata (dates, users, calibrations etc.) as well as all
audit trails, in a single encrypted file.
• Agilent 7890 A/B, 6890/6850 and 5890 GCs
• Bruker 436, 456, 430 and 450 GCs
• Varian 430, 450, 3800 and 3900 GCs
• CTC CombiPal and xt
• Agilent 1100, 1200 and 1260 LC
• Varian Star 800/850 MIB Interface (analog input,
relays, RS-232, GPIB)
• National Instruments 9181/4, 9219, 9401, 9481, 9265
(analog input, relays, TTL I/O, 4-20mA out)

Also, all Galaxie instrument control drivers are supported

as well securing the transition from Galaxie CDS to
CompassCDS.

These files provide users with a single point of reference

for all information pertaining to a single injection and
importantly, provide easily transferrable data repositories
for technical support.

The optional CompassDB application which can be

installed on current versions of SQL server or Oracle
provides an inexpensive additional layer of redundancy.
CompassDB automatically stores copies of entire .DATA
and other CompassCDS file types as Binary Large Objects
(BLOBs) and metadata in relational database tables,
creating a searchable data archive, the contents of
which can be used to rebuild and recover entire .DATA
files should these have been lost or corrupted on the
CompassCDS server.
Multi-Language User Interface
CompassCDS features a multi-language GUI supporting any language and helping to comply to national regulations
and to shift user friendliness and overall acceptance of CompassCDS to highest level. Within or even across
laboratories of multinational companies every user can thus decide for the preferred language to work with.
Chromatography Data Handling & More
Built-in capabilities to convert data into information:
Summary Reports use results from any number of
chromatograms, taken in a single sequence or over the
past months or even years, and calculate averages and
standard deviations. Summary Reports can also plot and
evaluate trends in data, detecting and flagging changes in
chromatographic systems before these changes can
compromise operation.
System Suitability software determines the quality of a
chromatographic analysis, calculating parameters such
as peak asymmetry and column efficiency. The software
can compare the results generated from injected control
samples to their expected concentrations. Limits put on
these results can then be used to determine the best
action to take to correct potential problems and ensure
the integrity of data and results.
Column Tracker, an integrated database, keeps track of
the identity and usage for all system columns. Every time
an injection is made, Column Tracker records the injection
– no matter which instrument or which column is being
used. This information is stored in the database, as well as
with each data file, providing a completely documented
and traceable usage and performance history for every LC
or GC column.
Print Manager allows users to conveniently export
reports and chromatograms, in multiple formats to one
or more network printers. CompassCDS can automatically
convert chromatogram results to many different formats
such as ASCII, Excel, or AIA, simplifying the ability to
perform further calculations or modeling. Furthermore,
it’s easy to interface with other systems like LIMS, LES or
ERP.
PDA and FLD spectral processing software determines the
identity and purity of peaks, and displays the information
both graphically and numerically for easy interpretation.
Purity and identity information is integrated into standard
chromatographic reports for a complete analysis of each
sample.
CompassCDS - Your premier choice in CDS
AnIML Converter and Viewer converts .DATA raw and
metadata information into a specific human-readable XML
format for long-term storage. AnIML (Analytical Mark-up
Language) files can be saved together with the original
.DATA file in a LIMS, LES or ERP, and reviewed at any time
in detail with a specific viewer even after decades of years
and without having the need to run CompassCDS natively.
Additionally, AnIML helps to facilitate data exchange data
within or across workgroups or research and development
organizations, and to finally overcome the limitation of
pure PDF-based documentation for long-term archival.
SCION-Certified Consumables for Your SCION GC
SCION GC columns span a broad range of column lengths,
diameters, stationary phases, and materials including:
Fused Silica (FS) and Inert Steel (IS). Ideal for either routine
or research type analyses, Scion GC columns cover a wide
range of applications and include:

Standard WCOT (Wall Coated Open Tubular)

Solid Stationary Phase PLOT (Porous Layer Open Tubular)
Inert Steel Micro-Packed and Packed

Super Clean™ Gas Filters

SCION Gas Purification Systems have the range to satisfy

your needs from individual to combination filters, from
Ultra purity combined with Ultra capacity, to all in one
solution kits. Innovative features designed into the product
yield extensive benefits to the user.

• Ultra-high capacity for long life, less change and

improved productivity

• High-purity output ensures 99.9999% Pure Gas

• “Quick connect” fittings for easy, leak-tight filter

changes

• Glass internals prevent diffusion; plastic externally for

safety

• Easy-to-read indicators for planned maintenance and

improved up-time

SCION Instruments
Headquarters USA Office
1 Bain Square 3019 Alvin Devane Blvd.
Kirkton Campus Suite 120
Livingston, Scotland Austin, TX
EH54 7DQ 78741
United Kingdom United States
+44 1506 300 200 844-547-0022
sales-eu@scioninstruments.com sales-us@scioninstruments.com

SI501703 ©SCION Instruments 2017