Lec 5 /

21. (a) Peanut oil: Volume = 100 g / 0.92 g/mL = 108.7 mL

(b) Castor oil: Volume = 100 g / 0.96 g/mL = 104.2 mL

(c) Polysorbate 80: Volume = 100 g / 1.08 g/mL = 92.6 mL

(d) Phosphoric acid: Volume = 100 g / 1.59 g/mL = 62.9 mL (for 85% solution)

(e) Mercury: Volume = 100 g / 13.6 g/mL = 7.4 mL

22.

Convert 1 lb to grams: 1 lb = 453.592 g

Use the specific gravity to convert grams to milliliters: 453.592 g ÷ 1.120 g/ml ≈ 405 ml

23 .

density of sulfuric acid = specific gravity of sulfuric acid x density of water

density of sulfuric acid = 1.83 x 1 kg/L = 1.83 kg/L

volume = mass / density

volume = 1 kg / 1.83 kg/L = 0.54645 L

volume = 0.54645 L x 1000 mL/L = 546.45 mL

Lec 6 /

43.

(a) 2.7 mg hydrocortisone in 15 g of cream = 1.8% (w/w)

(2.7 mg / 15 g) x 100% = 0.018 x 100% = 1.8%

(b) 27 mg hydrocortisone in 15 g of cream = 18% (w/w)

(27 mg / 15 g) x 100% = 0.18 x 100% = 18%

(c) 0.54 g hydrocortisone in 30 g of cream = 1.8% (w/w)

(0.54 g / 30 g) x 100% = 0.018 x 100% = 1.8%

(d) 54 mg hydrocortisone in 30 g of cream = 36% (w/w)

(54 mg / 30 g) x 100% = 0.36 x 100% = 36%

44 .

Weight of benzoin tincture = Volume of tincture x Specific gravity x Density of water

= 18 mL x 0.88 x 1 g/mL

= 15.84 g

Total weight of mixture = Weight of benzoin tincture + Weight of Peru balsam + Weight of cold
cream

= 15.84 g + 10 g + 70 g

= 95.84 g

Percentage strength (w/w) = (Weight of benzoin tincture / Total weight of mixture) x 100%

= (15.84 g / 95.84 g) x 100%

= 16.5% w/w

45 .

For 15-g tube:

0.05/100 x 15 = 0.0075 grams of drug

For 45-g tube:

0.05/100 x 45 = 0.0225 grams of drug

Difference in quantity:

0.0225 - 0.0075 = 0.015 grams of drug

46.

Convert the percentage of azelaic acid from a percentage to a decimal by dividing by 100: 15% / 100
= 0.15

Multiply the total mass of the ointment (30 g) by the decimal percentage of azelaic acid (0.15): 30 g x
0.15 = 4.5 g