Professional Documents
Culture Documents
6. Loop of Henle Reabsorption of Na+ and Cl- in ascending limb and water in
descending limb
- concetration of filtrate
7. Distal Tubule - secretion of K+, H+ and ammonia
- reabsorption of water- regulated by ADH, and reabsorp- tion
of HCO3--
- regulation of Ca2+ and PO42- by parathyroid hormone
- regulation of sodium and potassium by aldosterone
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14. Ascending Limb Chlorid ions are reabsorbed and sodium ions
17. Aldosterone - released from adrenal cortex's acts on the distal tubule to
im- portance cause reabsorption of Na+ and water
- in exchange, K+ is excreted
18. Myocyte cells release ANP- atrial natriuretic peptide, in response to atrial
in the Right distention which is a result of an increase plasma volume
atrium - ANP acts on kidneys to increase sodium excretion
- ANP inhibits renin, ADH and suppresses aldosterone
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21. Prostaglandins - many body tissues synthesize PGs from precursor, ara-
chiodinc acid
- in the kidney, PG synthesis occurs in the medulla
- have vasodilating actions, increasing renal blood flow,
promote Na+ excretion
- counteract vasoconstrictor effect of AGII and norepi
- may lower BP by decreasing vascular resistance
22. Ureters - tubes that carry urine from the renal pelvis to the bladder
- smooth muscle fibers contract to promote the peristaltic one
way flow of urine through the ureters
- distention, neurologic and endocrine influences and
drugs can affect these muscle contraction
- renal pelvis only holds 3-5mL, kidney damage can result
from a backflow of more than that amount of urine
- the Ureterovesical junctions rely on ureter's angle of blad- der
penetration and muscle fiber attachments to prevent backflow
of urine into the ascending infection
- when bladder pressure rises like with voiding or cough- ing,
muscle fibers that the ureter shares with the bladder base
contract first, promoting ureteral lumen closure, next contracts
and the base ensuring UVJ closure and preven- tion of urine
reflux through the junction
23. Bladder - stretchable organ positioned behind the pubis and ante- rior
to the vagina and rectum
- primary function= reservoir for urine and to eliminate
waste
- normal adult urine output is 1500mL/day
- the volume of urine produced at night is less than half to that
formed during the day because of hormones-- this diurnal
pattern is normal
- typically an individual will urinate 5-6x during the day and
occasionally at night
24. Bladder- Trigone - triangular area formed by the 2 ureteral openings and the
bladder neck
- affixed to the pelvis by ligaments
- the bladder muscle= detrusor is composed of layers of
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intertwined smooth muscle fibers capable of considerable
distention during bladder filling and contraction during
emptying- it is attached tot he abdominal wall by the liga-
ment- arches- as the bladder fills it therefore rises towards the
umbilicus
27. Urethra - small tube that incorporates the smooth muscle of the
bladder neck and extends to the started muscle of the
external meatus
- primary function is to serve as a conduit for urine from the
bladder to the outside of the body during voiding and to
control voiding
- female urethra is 1-2in long and lies behind the symph- ysis
pubis anterior to the vagina
- male- 8-10in long originates at the bladder neck and
extend the length of the penis
28. Urethrovesical - together the bladder, urethra, and pelvic floor muscles = this
Unit - voluntary control of this unit = continence
- stimulating and inhibiting impulses are sent from the brain
through the thoracolumbar and sacral areas of the spinal cord
to control voiding
- distention of the bladder stimulates stretch receptors
within the bladder wall
- impulses are transmitted to the sacral SC and brain
causing a desire to urinate
- if the time to void is not appropriate, inhibitor impulses in
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the brain are stimulated and transmitted back through the
thoracolumbar and sacral nerves innervating the ladder
- in a coordinated fashion, the detrusor muscle accom-
modates to the pressure (does not contract) while the
sphincter and pelvic floor muscles tighten (contract) to
resist bladder pressure
- if voiding is appropriate, carbine inhibition is voluntarily
suppressed, and impulses are transmitted via the SC for the
bladder neck, sphincter, and pelvic floor muscles to relax and
for the bladder to contract- sphincter closes and detrusor
muscles relax when bladder is empty
29. Gerontologic - 20-30% decrease in size and weight in the kidney be-
Considerations tween 30-90 years old
Paragraph - by 70s, glomerular have lost 30-50% of their function
- despite these changes, older people maintain fluid home-
ostasis unless diseased or stress
- decreased renal blood flow, in part due to atherosclero- sis,
resulting decreased GFR
- alterations in hormones- ADH, aldosterone, ANP result in
decreased urinary concetration, and alterations in the
excretion of water, sodium and avoid, and potassium
- under normal conditions aging kidney an maintain home-
ostasis but may not
- female urethra, bladder, vagina, pelvic floor have loss of
elasticity and muscle support- older women prone to
bladder infections and incontince
- prostate enlarges as men age may affect urinary pat- terns-
causing hesitancy, retention, slow stream and- blaider
infection
- constipation= common compliant in older adults, can
affect urination
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less concentrated urine
Ureter, Bladder, Urethra
- decreased elasticity, weakening of urinary sphincter, de-
creased bladder capacity, estrogen deficiency leading to
thin dry vagina, increased bladder contractions, prostatic
enlargement
- palpable bladder after urination because of retention
- stress incontince especially during valsalva maneuver-
dribbling of urine after urination
- frequency, urgency, nocturia,
stress or overactive bladder
31. Assessment - past health history
- medications
- surgery
33. Objective Palpa- - Costovertebral Angle- formed by the rib cage and verte-
tion bral column
- the normal left size kidney is rarely palpable because the
spleen lies directly on top of it
- occasionally, the lower pole of the right kidney is palpa-
ble- smooth rounded mass that descends on inspiration
- if not palpable note its size, contour and tenderness
- kidney enlargement suggests neoplasm or serious renal
disease
- urinary bladder is NOT palpable unless it is distended
with urine- smooth round firm organ sensitive to palpation
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35. Auscultation - the bell may be used to osculate over CVAs and upper
abdomen quadrants
- abdominal aorta for bruit--> impaired blood flow to kid-
neys
36. Review 20-30 % loss in size & weight of kidney between 30-90 yrs
Gerontol- ogy Loss most in cortex
Considera- By 7th decade 30-50% of glomeruli have lost function It
tions- her slide, shrinks, looses its ability
extra important Usually do okay, until they encounter diseases or other
physiologic stressors
Women
38. Women vs. - estrone levels decrease with age, tissues become less elastic,
men changes thin, less vasculature- older women prone to ure- thral
irritation and bladder infections and incontinence, Men
- prostates enlarge- hesitancy, retention, slow stream,
bladder infections
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44. Incontinence inability to voluntarily control discharge of urine- bladder
infection or injury to external sphincter
45. Nocturia frequency of urination at night
46. Oliguria Diminished amount of urine in a given time
24hr urine output of 100-400 mL
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- at end as patient to urinate and add that
- must be refrigerate or preservatives added
52. Urine Culture - confirms suspected UTI and identifies organisms
- normally, bladder is sterile but urethra contains few WBC
>10^5 = indicates infection
<10,000 no infection
>100,000 indicates infection
Nursing
- use sterile container for collection of urine
- touch only outside of container
- for women separate labia with one hand and clean mea-
tus with other hand using at least 3 sponges in a front to
back motion
- for men retract foreskin and cleans glands with at least 3
sponges
- after cleaning instruct patient to start urinating and then
continue voiding into sterile container- the initial urine
flushes to most contaminants in the urethra
- catheterization may be needed
- ideally from first void of the day and not after recent
void/bowel movement
- mid stream sample recommend in males and females
- most presses is straight cauterization
54. Residual Urine determines amount of urine left in bladder after urinating
<50mL urine
nursing
- immediately after urinates use bladder ultrasound
57. BUN/Ct ratio - increased ratio due to decrease in blood flow to kidneys,
GI bleed
12:1 or 20:1
61. Calcium total - main mineral in bone and aids in muscle contraction,
neurotransmission and clotting
- in kidney disease, decreased reabsorption --> renal os-
teodystrophy
8.6-10.2
post puncture bleeding
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63. Bicarbonate most patients in renal failure have metabolic acidosis and low
serum HCO3- levels
Normal 22-26
explain and watch for bleeding
64. Kidneys, ureters, - show size
bladder xray - can be done portable or radiology
KUB - radiopaque stones
- perform bowel prep if ordered
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evaulates upper urinary tract when patient has allergy to
contrast media
- explain procedure prepare for IVP
68. Renal ultrasound - used to detect masses cysts, some probe is placed in skin
- conductive gel is applied
- noninvasive procedure
- computer interprets tissue density
- explain
- because radiation exposure is avoided, a number of
images can be obtained
- bowel prep is NOT required
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depending on patient
- lithotomy osier is used***
Nursing
Before force fluids or give IV fluids if GENERAL anesthesia
to be used, ensure concept form is signed ****** explain
After- explain that burning on urination, pink-tinged urine and
urinary frequency are expected effects*****
- observe for bright red bleeding which is NOT normal
- do NOT let patient walk alone immediately after proce-
dure because orthostatic hypotension may occur
- offer warm sitz baths, heat, mild analgesics to avoid
discomfort
73. Urinalysis- Color Normal- amber yellow
abnormal- dark, smoky color, yellow brown, to love green,
orange red, coldness, colorless
74. Urinalysis- Odor Normal= aromatic
Abnormal- ammonia like odor, unpleasant order
81. Urinalysis- pH
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Normal- 4-8 average is 6
Abnormal >8
82. Urinalysis- RBC normal 0-4/hpf
abnormal <4.0 or >4/hpf
83. Urinalysis WBC Normal 0-5/hpf
Abnormal >5 hpf
84. Urinalysis Casts Normal- none
Abnormal- present
- casts are a product of RBC and WBC breakdown in the renal
tubules which result in cast snap objects indicative of WBC
and or RBC
87. Urodynamics - set of tests designed to measure urinary tract function- how
well by can eliminate the urine
1. less invasive- urinary flow study
2. more invascive
- cystometrogram
- sphincter electromyography
- voiding pressure flow study
- videorodynamics
- whitaker study
88. Urine Flow study - type of urodynamics
- meausre urine volume in a single voiding expelled in a
period of time
- used to assess degree of outflow obstruction, assess
bladder or sphincter dysfunction, evaluates treatment
normal max flow for men 20-25mL/sec, women
25-30mL/sec
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- age can affect it
nursing
- explain procedure
- ask to start with comfortably full bladder
- try to empty completely
- measure residual urine volume
89. Cystometrogram types of urodynamic study
- evaluates bladder's capacity to contract and exel urine
- involves insertion of catheter and installation of water or
salon solution into bladder
- measurements of pressure exerted against bladder wall ar
recorded
- if abnormal pressure i.e. measured, a second tube is
inserted into the rectum or vagina
- especially detrusor muscle if there is a spinal cord injury
could affect this
nursing
- explain procedure
- during the infusion ask patient about sensation of bladder
filling and first desire urge to urinate
- observe for infections after
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cialized toilet to urinate while the various tubes and EMG
apparatus are in place
97. Renal Biopsy - obtains renal tissue for examination to determine kidney
disease or flow up
- technique is usually done as a skin percutaneous biopsy
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through needed insertion into lower lobe of kidney
- can be performed with CT or ultrasound guidance
- absolute contraindications: bleeding disorders, single
kidney, uncontrolled hypertension
Nursing
- type and crossmatch patient blood, ensure concept is
signed
Before
- ascertain coagulation status throughout patient history,
medication history, CBC, hemoatcrit, PT time and bleeding and
clothing time. Patient should NOT BE TAKING Aspirin or
Warfarin- usually stop 5 days before
After
- apply pressure dressing and keep patient on affected side
for 30-60 minutes
- bed rest for 24 hours**
- vital signs every 5-10 mins for the first hour
- assess for flank pain, hypotension, decreasing hemat- ocrit,
fever, chills,
- urine dipstick can be used to test for bleeding in the urine
- instruct patient to avoid lifting heavy objects for 5-7 days
and to not take anticoagulant drugs until allowed by HCP
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