Martin, Nicole Rachelyn E.

CI: Edna Alvarez, RN, MAN

Group 2-D
DRUG STUDY

Name of Drug Mechanism of Indication Dosage Contraindication Adverse Action Nursing Responsibility
(Classification) Action

Generic Name: - Erythromycin - To prevent neonatal Ophthalmic Eyes: Allergic reactions: - Cleanse the infant’s eyes as
ERYTHROMYCIN ophthalmic conjunctivitis and ointment: blurred vision skin rash, itching, hives, needed before application.
Brand names: preparations are ophthalmia -2% ointment Body as a whole: swelling of the face, lips, - Hold the tube in a horizontal
used to treat neonatorum (Apply 0.5– Fever, tongue, or throat. rather than a vertical position.
- Pediazole eosinophilia,
infections of the 1cm ribbon in - Do not touch the tip of the tube to
Classification: urticaria, skin
eye. They also may lower any part of the eye.
- Macrolides eruptions, fixed drug
be used to prevent conjunctival - Administer from the inner
eruption,
certain eye sacs shortly canthus to the outer canthus.
anaphylaxis,
infections of after birth) - Apply 0.5–1 cm ribbon in lower
Superinfections by
newborn babies, conjunctival sacs shortly after
nonsusceptible
such as neonatal birth.
bacteria, yeasts or
conjunctivitis and - Observe for irritation.
fungi.
ophthalmia
neonatorum. They Skin:
may be used with (topical use)
other medicines for Erythema,
some eye desquamation,
infections. burning, tenderness,
dryness, or oiliness,
pruritus.

Generic Name: - Phytonadione is - Vitamin K is needed -Intramuscular -Hypersensitivity Adverse Reaction: - Document the giving of the medication
- VITAMIN K used in prophylaxis for blood clotting. injection is - Pain and edema may occur to newborn to prevent an accidental
and treatment of - Newborn babies are given in the at injection site. Allergic doubling of the dose.
Brand Name: hemorrhagic given vitamin K vastus reaction such as rash and - Observe for bleeding (usually occurs on
- Phytonadione disease of the injections to prevent lateralis thigh urticaria, may also occur. second or third day). Bleeding may be
newborn. It a serious disease muscle. A seen as generalized ecchymoses or
promotes liver called hemorrhagic one-time only bleeding from umbilical cord,
Classification:
formation of the disease of the prophylactic circumcision site, nose or
- Fat-Soluble
clotting factors II, newborn (HDN). dose of 0.5 to gastrointestinal tract.
VII, IX and X. At 1 mg is given - Observe for jaundice and kernicterus,
birth, the newborn intramuscular especially in preterm infants.
 does not have ly in the - Observe for signs of local
bacteria in the birthing area inflammation.
colon that within 1 hour - Apply pressure to the injection site to
necessary for of birth. prevent further bleeding
synthesizing fat- - Protect drug from light.
soluble vitamin K. - Give vitamin K before circumcision
Therefore, the procedure
newborn may have
deceased levels of
prothrombin during
the first 5 to 8 days
of life reflected by
a prolongation of
prothrombin time.

Generic Name: - As an - Used to protect - 0.05 mL via - BCG vaccine is - Erythema nodosum - Monitor for S&S of systemic BCG
- BACILLUS immunostimulant tuberculin skin test slow injection contraindicated in lymphadenopathy infection: fever chills, severe malaise
CALMETTE- that is used to negative infants and into the deltoid patients with a erythema, fever, urticaria or cough.
GUERIN (BCG) stimulate the children and groups muscle. hypersensitivity to any CNS: malaise fever. - Culture blood and urine, if systemic
VACCINE immune system to with an excessive rate component of the GI: nausea, vomiting, infection is suspected.
Brand names: produce immunity of new TB infections, vaccine including anorexia, diarrhea. - Assess for regional lymph node
against carcinoma in site of monosodium GU: dysuria, urinary enlargement and report fistula
- BCG Vaccine tuberculosis. The glutamate
the bladder. frequency, hematuria, formation.
Classification: Calmette-Guerin hypersensitivity and cystitis, urinary urgency
- BCG Virus Vaccine strain of M. bovis polysorbate 80 Hepatic: liver dysfunction
present in BCG hypersensitivity the
vaccine is vaccine is also
immunologically contraindicated in
similar to M. patients with an
tuberculosis. anaphylactic or other
Vaccination with allergic reaction to a
BCG simulates previous dose of BCG
natural infection vaccine
with M.
tuberculosis and
results in a cell-
mediated immune
reaction and
immunity against
tuberculosis.
 Vaccination with
BCG usually
causes tuberculin
sensitivity, but the
degree of
sensitivity is
variable

Generic Name: - Hepatitis B - Indicated for - Intramuscular - Anaphylactic - Diarrhea, loss of appetite; - Determine vaccine to be administered;
- HEPA B vaccine immunization suspension reaction to previous - Feeling weak or tired; cautions or contraindications to
VACCINE recombinant is against infection (pediatric/adole hepatitis B vaccine - Mild fussiness or crying; receiving the vaccine.
Brand names: used to prevent caused by all known scent dose. - Low fever; or - Select the correct needle length and
infection by the subtypes of hepatitis formulation) - Moderate or severe runny nose. injection site.
- Engerix B, Nabi
hepatitis B virus. B virus; acute illness. - Use age-appropriate interventions to
HB, Heplisav B The vaccine -Immunoprophylaxis - 5 mcg/0.5 ml reduce pain.
Classification: works by causing against Hepatitis B. (Recombivax - Monitor: observe for at least 15
- Vaccine your body to HB) minutes for severe reaction
produce its own - 10 mcg/0.5
protection mg (Engerix
(antibodies) B)
against the
disease.