Name of Dosage, Mechanism of Indication Contraindication Adverse Effect Nursing Responsibility

Drug Route and Action

Frequency
Generic Dosage: After topical ocular Ophthalmic - Hypersensitivity to - The most Interventions:
Name: dosing, nepafenac nepafenac is used the active substance frequently reported
penetrates the cornea to treat eye pain, ocular adverse events
1 gtts and is converted by redness, and following cataract - Consider the history of
Nepafenac ocular tissue swelling in - Hypersensitivity to surgery were hypersensitivity to the drugs or one
0.1%, oph. hydrolases to patients who are other nonsteroidal capsular opacity, of its components
susp Frequency: amfenac, a recovering from anti-inflammatory decreased visual
nonsteroidal anti- cataract surgery drugs (NSAIDs). acuity, foreign body
inflammatory drug. (procedure to sensation, increased - Monitor cornea; discontinue if
Amfenac is thought treat clouding of intraocular pressure, corneal epithelial breakdown
Brand Name: TID
to inhibit the action the lens in the - Patients in whom and sticky sensation. occurs
of prostaglandin H eye). Nepafenac attacks of asthma, These events
synthase is in a class of urticaria, or acute occurred in
Nevanac Route: (cyclooxygenase), an medications rhinitis are approximately 5 to
- If more than one topical
enzyme required for called precipitated by 10% of patients.
ophthalmic medication is being
prostaglandin nonsteroidal anti- acetylsalicylic acid
Opthalmic Other ocular adverse used, the medicines must be
production. inflammatory
Route OU events occurring at administered at least 5 minutes
drugs (NSAIDs). or other NSAIDs.
Classification: an incidence of interval.
It works by
approximately 1 to
stopping the - Apply eyedrops and ointment
5% included
production of from less concentrated to more
Nonsteroidal conjunctival edema,
certain natural concentrated texture.
Anti- corneal edema, dry
substances that
inflammatory eye, lid margin
cause pain and
Drug crusting, ocular
swelling. Teaching Points:
discomfort, ocular
hyperemia, ocular
pain, ocular pruritus,
photophobia, tearing - Patients should be informed of the
and vitreous possibility that slow or delayed
healing may occur while using
detachment. nonsteroidal anti-inflammatory
drugs.

Other
contraindications: - Patients should be instructed to
avoid allowing the tip of the
- Bleeding
dispensing container to contact the
tendencies
eye or surrounding structures
- May delay wound because this could cause the tip to
healing become contaminated by common
bacteria known to cause ocular
- Rheumatoid infections.
arthritis
- Diabetes
- Serious damage to the eye and
- Contact lenses subsequent loss of vision may
(remove during result from using contaminated
therapy) solutions.
- Pregnancy (avoid
during 3rd trimester)
- Nursing mothers - Instruct patient nevanac should
not be administered while wearing
contact lens.

- Patients should be advised that if

they develop an intercurrent ocular
condition (e.g., trauma, or
infection) or have ocular surgery,
they should immediately seek their
physician’s advice concerning the
continued use of the multidose
container.
- Patients should be advised to
shake the bottle well.