DRUG STUDY

Common medications in the OB Ward for Normal Spontaneous Delivery:

Nam Class Action Indication Contraindic Side Effects Advers Nursing

e of ificati ations e Responsi
Drug on effects bilities
Asco Antiox Absorption is • Vitamin C • Blood • Diarrhea • Heada • Usually
rbic idant through an Deficiency: Disorders: • Nausea ches, administe
Acid energy- • Scurvy thalassemia • Heartburn flushi red
dependent • Gingivitis G6PD • Fatigue ng, orally, th
process that has • Asthma deficiency • Flushing nause e drug
two • Glaucoma sickle cell • Headache a or may be
mechanisms: • Collagen disease • Difficulty vomiti administe
simple diffusion Disorders Hemochromat falling asleep ng, red
and active • Heatstroke osis or staying and intramusc
transport. Two • Arthritis • Avoid taking asleep dizzin ularly,
transporters are • Infections supplement • gas ess intraveno
involved: SVCTs (pneumoni s (IV usly (IV),
(sodium- a, sinusitis, immediately use). or
dependent rheumatic before or • Migrai subcutan
vitamin C fever) following ne eously
transporters) and • Chronic angioplasty. heada when mal
hexose illnesses • Diabetic ches absorptio
transporters. The • Hemovasc patients with a n is
site for ular should take daily suspecte
absorption is the Disorders vitamin C dose d.
distal small • Burns supplement of 6 For IV inj
intestine and is • delayed s with care g. ection, mi
regulated by wound as it raises • Signifi nimize
renal excretion. healing blood sugar cant adverse
Usual dietary • The elderly levels. amou reactions
doses of up to • Those with nts of by dilutin
100 mg/day are alcohol use vitami g the
almost disorder, nC drug with
completely anorexia, can normal
absorbed. The or cancer increa saline or
highest ascorbic • Practicing se the glucose.
acid food fads risk of • The
concentrations • Those with kidne average
are in the presumed y protective
pituitary gland, food stone adult
the adrenal allergies s and dose of
gland, the brain, • Receiving elevat vitamin C
leukocytes, and unsupplem e uric is 70 to
the eyes. ented acid 150 mg
Ascorbic acid parenteral and daily.
functions as a nutrition oxalat Increase
cofactor, enzyme • Those on e the dose
complement, co- restricted becau to 300
substrate, and a diets se it mg to 1 g
 powerful anti- secondary acidifi daily whe
oxidant in to es the n scurvy
various reactions inflammato urine. is
and metabolic ry bowel present.
processes. It disease, • Vitamin C
also stabilizes gastrointes (in
vitamin E and tinal reflux, grams)
folic acid and or Whipple can give
enhances iron disease false
absorption. It • Those who negative
neutralizes free smoke stool
radicals and tobacco guaiac
toxins as well as products results
attenuates • Taking and is
inflammatory medication rarely
response, s such as associate
including sepsis aspirin, d with
syndrome. indometha fatal
cin, oral cardiac
contracepti arrhythmi
ves, as in
tetracyclin patients
es, and with iron
corticoster overload.
oids.
• Those who
have renal
failure due
to filtration
of water-
soluble
vitamin C
during
dialysis
• Those with
a
complicatio
n of
interleukin-
2
treatment
of
metastatic
renal cell
carcinoma
• Receiving
liver
transplants
Ferro Iron Taking iron in Used for the • Hemochro • Metallic The Assessmen
us Produ supplement prevention matosis, taste toxicity t and
Fum cts form, such as and hemosider • Temporary of monitoring:
arate ferrous sulfate, treatment of osis, hemol staining of ferrous All iron
allows for more iron ytic teeth sulfate preparation
rapid increases deficiency anemia (un enamel in s
in iron levels anemia in less an • Nausea humans Assess
when dietary adults and iron- • Vomiting depend
supply and children. deficient • Abdominal s on the• Signs and
stores are not state is pain amount symptoms
sufficient. Iron is also • Flatulence of iron of iron
transported by present) • Constipation ingeste deficiency
the divalent • Hypersensi • Dark, tarry d. Up to anemia;
metal transporter tivity stool 20 e.g., pallor,
1 (DMT1) across • iron • Skin staining mg/kg tachycardia
the metabolism • Phlebitis of , dyspnea,
endolysosomal disorder • Anaphylactic element and fatigue
membrane to causing reactions al iron • Laboratory
enter the increased • Skin staining is not test
macrophage. It iron • Phlebitis toxic, results:
can then can be storage 20-60 CBC,
incorporated into • an overload mg/kg hemoglobin
ferritin and be of iron in has ,
stored in the the blood mild hematocrit,
macrophage or • a type of toxicity, iron level,
carried of the blood and ferritin,
macrophage by disorder more total iron-
ferroportin. This where the than 60 binding
exported iron is red blood mg/kg capacity
oxidized by the cells burst can
enzyme to called lead to Monitor
ceruloplasmin to hemolytic severe
Fe3+, followed anemia sympto• Evidence of
by sequestration • an ulcer ms and increased
by transferrin for from too morbidit oxygen-
transport in the much y carrying
serum to various stomach capacity of
sites, including acid RBCs
the bone marrow • a type of • Increased
for hemoglobin stomach hemoglobin
synthesis or into irritation and
the liver. Iron called hematocrit
combines with gastritis • Side effects
porphyrin and • ulcerative • Toxicity
globin chains to colitis, an • Anaphylaxi
form inflammato s
hemoglobin, ry condition
which is critical of the Client
for oxygen intestines education:
delivery from the • diverticular All iron
lungs to other disease preparation
tissues. • excess iron s
due to
repeated • Purpose of
blood medication:
transfusion helps
s relieve
• Hemochro symptoms
matosis of anemia
by
• Thalassemi providing
a iron to
• Hemolytic make
anemia hemoglobin
• Peptic for red
ulcer blood cells,
disease increase
• Gastritis the
• Inflammat oxygen-
ory bowel carrying
disease capacity of
• Regional blood
enteritis PO
• Client
education

• Take
medication
between
meals with
orange
juice or
vitamin C
supplement
o Increases
iron
absorption;
decreases
metallic
taste
o May take
medication
with food
to decrease
gastrointes
tinal side
effects
o Avoid
taking
medication
with
dietary
fiber, eggs,
milk,
coffee, or
tea
• Remain
upright for
at least 30
minutes
after
administrati
on
o Decreases
irritation to
esophagus
• Liquid
preparation
s
o Avoid teeth
staining
▪ Dilute iron
with water
or juice
▪ Use a
straw
▪ Rinse or
brush
immediatel
y
afterwards
• Include
iron-rich
foods in
diet; e.g.,
lean red
meats,
green leafy
vegetables,
fortified
cereals
• Stools may
turn dark
green or
black
o Discoloratio
n is
harmless
• Constipatio
n
o Increase
fluids,
dietary
fiber,
physical
activity as
tolerated
• Early
symptoms
of iron
toxicity;
e.g.,
nausea,
vomiting,
diarrhea,
abdominal
pain
o Seek
medical
attention
immediatel
y
• Keep iron
supplement
s out of the
reach of
children
o Common
cause of
fatal
poisoning
IV / IM
Assessmen
t,
interventio
ns, and
monitoring
IV

• Confirm a
patent IV
• Emergency
equipment
and
injectable
epinephrin
e readily
available
• Administer
prescribed
test dose
o Observe for
signs of
anaphylaxis
for at least
15
minutes;
e.g.,
flushing,
difficulty
breathing,
a weak,
rapid pulse,
hypotensio
n
o New IV site
if burning
or pain
occurs
o Monitor for
tissue
 staining;
phlebitis

IM

• Use Z-track
method
o Prevents
medication
leakage
and
irritation
o Monitor
injection
site for
tissue
staining,
irritation,
and pain
Mefe NSAI Mefenamic acid • Mild pain Not Common Oral, Assessmen
nami D- binds the • Primary recommende• Bloody urine rat t & Drug
c nonst prostaglandin Dysmenorr d to use with• bloody, black, LD50: Effects
Acid eroida synthetase hoea Ketorolac. or tarry stools 740 ▪ Assess
l anti- receptors COX-1 • Gastrointes • decreased mg/kg. patients
inflam and COX-2, tinal Acute frequency or Sympto who
mator inhibiting the cramping bronchospas amount of ms of develop
y drug action of • Moderate m, asthma, urine overdos severe
prostaglandin Pain nasal polyps,• heartburn e may diarrhea
synthetase. As NSAID • increased include and
these receptors hypersensitivi bleeding time severe vomiting
have a role as a ty, salicylate • increased stomac for
major mediator hypersensitivi blood pressure h pain, dehydratio
of inflammation ty, urticaria • increased thirst coffee n and
and/or a role for Mefenamic • indigestion ground- electrolyte
prostanoid acid is • itching, skin like imbalance.
signaling in contraindicate rash vomit, ▪ Lab tests:
activity- d in patients • loss of appetite dark With long-
dependent with salicylate• lower back or stool, term
plasticity, the hypersensitivi side pain ringing therapy
symptoms of ty or NSAID • nausea in the (not
pain are hypersensitivi• pale skin ears, recommen
temporarily ty who have • severe change ded) obtain
reduced. experienced stomach pain, in periodic
asthma, cramping, or amount complete
urticaria, or burning of blood
other allergic• stomach urine, counts, Hct
reactions bloating unusual and Hgb,
after taking • swelling of the ly fast and kidney
aspirin or face, fingers, or slow function
other feet, or lower heartbe tests.
NSAIDs. legs at, Patient &
Severe, rarely • trouble muscle Family
fatal, breathing weakne Education
anaphylactoid ss, slow
reactions to • unusual or ▪ Discontinue
mefenamic bleeding or shallow drug
acid have bruising breathi promptly if
been • unusual ng, diarrhea,
reported in tiredness or confusi dark stools,
such patients. weakness on, hematemes
Mefenamic • vomiting severe is,
acid should • vomiting of headac ecchymose
not be used material that he or s, epistaxis,
in patients looks like loss of or rash
with aspirin- coffee conscio occur and
sensitive grounds, usness do not use
asthma or the severe and again.
aspirin triad continuing Contact
because of • weight gain physician.
the • weight loss ▪ Notify
approximate • physician if
5% cross- persistent
sensitivity GI
that occurs discomfort,
between sore throat,
aspirin and fever, or
NSAIDs. The malaise
triad typically occur.
occurs in ▪ Do not
patients with drive or
asthma who engage in
experience potentially
rhinitis with hazardous
or without activities
nasal polyps, until
or who response to
experience drug is
severe, known. It
potentially may cause
fatal, acute dizziness
bronchospas and
m after drowsiness.
taking aspirin ▪ Monitor
or other blood
NSAIDs. glucose for
loss of
glycemic
control if
diabetic.
▪ Do not
breast feed
while
taking this
drug
without
consulting
physician.
Celec NSAI Unlike most Celecoxib is • Hypersensiti • Cough headac • Assess
oxib D NSAIDs, which indicated for vity; • fever he, range of
inhibit both types symptomatic • Cross- • skin rash fever motion,
of treatment of sensitivity • sneezing (pyrexia degree of
cyclooxygenases adult may exist • sore throat ), upper swelling,
(COX-1 and osteoarthritis with other • swelling of abdomi and pain
COX-2), (OA) and NSAIDs, the face, nal in
celecoxib is a adult including fingers, feet, pain, affected
selective rheumatoid aspirin; or lower legs cough, joints
noncompetitive arthritis • History of nasoph before
inhibitor of (RA).31 Celec allergic-type aryngiti and
cyclooxygenase- oxib is not a reactions to s, periodical
2 (COX-2) substitute for sulfonamide abdomi ly
enzyme. COX-2 aspirin for s; nal througho
is expressed cardiovascula • History of pain, ut
heavily in r event asthma, nausea, therapy.
inflamed tissues prophylaxis.31 urticaria, or arthralg • Assess
where it is It may be allergic-type ia, patient
induced by also be used reactions to diarrhea for
inflammatory to treat acute aspirin or , and allergy to
mediators.31 The pain from other vomitin sulfonam
inhibition of this various NSAIDs, g. ides,
enzyme reduces sources, including the aspirin,
the synthesis of juvenile aspirin triad or
metabolites that rheumatoid (asthma, NSAIDs.
include arthritis in nasal polyps, Patients
prostaglandin E2 children over and severe with
(PGE2), 2, ankylosing hypersensiti these
prostacyclin spondylitis, vity allergies
(PGI2), and primary reactions to should
thromboxane dysmenorrhe aspirin); not
(TXA2), a.31 • Advanced receive
prostaglandin D2 Celecoxib, in renal celecoxib
(PGD2), and combination disease; .
prostaglandin F2 with tramadol • Severe • Assess
(PGF2). , is indicated hepatic patient
Resultant for the impairment; for skin
inhibition of management • Coronary rash
these mediators of acute pain artery frequentl
leads to the in adults bypass graft y during
alleviation of severe (CABG) therapy.
pain and enough to surgery; Discontin
inflammation.7,31 require an • OB: Avoid ue at
By inhibiting opioid use after 30 first sign
prostaglandin analgesic and wk of rash;
synthesis, non- in whom gestation. may be
steroidal anti- alternative life-
inflammatory treatments threateni
drugs (NSAIDs) are ng. SJS
cause mucosal inadequate.33 may
damage, develop.
ulceration and Treat
ulcer symptom
complication atically;
throughout the may
gastrointestinal recur
tract.31 Celecoxib once
poses less of an treatmen
ulceration risk t is
than other stopped.
NSAIDS, owing • Monitor
to its decreased for signs
effect on gastric and
mucosal symptom
prostaglandin s of
synthesis when DRESS
compared to (fever,
placebo.8 rash,
Celecoxib exerts lymphad
anticancer enopathy
effects by , facial
binding to the swelling)
cadherin-11 periodical
(CDH11)protein, ly during
which is thought therapy.
to be involved in Discontin
the progression ue
of tumors, and therapy if
inhibiting the 3- symptom
phosphoinositide s occur.
-dependent Lab Test
kinase-1 (PDK-1) Consider
signaling ations:
mechanism.22,17 I May cause
n addition, ↑ AST
celecoxib has and ALT
been found to levels.
inhibit carbonic • May
anhydrase cause
enzymes 2 and hypopho
3, further sphatemi
enhancing its a,
anticancer hyperkal
effects emia,
and ↑
BUN.
• Use
lowest
effective
dose for
shortest
period of
time.
• PO May
be
administ
ered
without
 regard to
meals.
Capsules
may be
opened
and
sprinkled
on
applesau
ce and
ingested
immediat
ely with
water.
Mixture
may be
stored in
the
refrigerat
or for up
to 6 hr.

Ampi Penicil Ampicillin is ampicillin UNASYN is • fever, Pain at General

cillin lins, similar to benzyl sodium/sulba contraindicate• sore throat, IM Dissolution
Sulb Amino penicillin in its ctam sodium d in patients • headache, injectio Procedures
acta bactericidal is a with a • rash, n site - UNASYN
m action against combination previous • diarrhea, 16% sterile
susceptible antibiotic indi history of • body aches, Pain at powder for
organisms during cated for the cholestatic • nausea, IV intravenous
the stage of treatment of jaundice/hep• vomiting, injectio and
active infections atic • stomach pain, n site - intramuscul
multiplication. It due to dysfunction • bloating, 3% ar use may
acts through the susceptible associated • gas, Thromb be
inhibition of cell strains of with UNASYN. • vaginal itching ophlebit reconstitut
wall microorganis or discharge, is - 3% ed with any
mucopeptide ms. • itching, Phlebiti of the
biosynthesis. • swollen/black/" s- compatible
Ampicillin has a Skin and Skin hairy" tongue, 1.2% diluents
broad spectrum Structure • thrush (white described
of bactericidal Infections patches inside The in this
activity against caused by your mouth or most insert.
many gram- beta- throat), or frequen Solutions
positive lactamase • pain, swelling, tly should be
and gram- producing or irritation reporte allowed to
negative aerobic strains where the d stand after
and anaerobic ba of Staphyloco needle is adverse dissolution
cteria. (Ampicillin ccus aureus, placed. reaction to allow
is, however, Escherichia s were any
degraded by coli,* diarrhea foaming to
beta-lactamases Klebsiella spp in 3% dissipate in
and therefore .* of the order to
the spectrum of (including K. patients permit
activity does not pneumoniae* and visual
normally include ), Proteus rash in inspection
organisms which mirabilis,* less for
produce these Bacteroides than complete
enzymes). fragilis,* 2% of solubilizatio
Enterobacter the n.
spp.,* patients Preparation
and Acinetob . For
acter Addition Intravenou
calcoaceticus. al s Use
* systemi 1.5 g and
Intra- c 3.0 g
Abdominal reaction Bottles:
Infections ca s UNASYN
used by beta- reporte sterile
lactamase d in less powder in
producing than piggyback
strains 1% of units may
of Escherichia the be
coli, patients reconstitut
Klebsiella spp were: ed directly
. itching, to the
(including K. nausea, desired
pneumoniae* vomitin concentrati
), Bacteroides g, ons using
spp. candidia any of the
(including B. sis, following
fragilis), fatigue, parenteral
and Enteroba malaise, diluents.
cter spp.* headac Reconstitut
Gynecological he, ion of
Infections ca chest UNASYN,
used by beta- pain, at the
lactamase flatulen specified
producing ce, concentrati
strains abdomi ons, with
of Escherichia nal these
coli,* distensi diluents
and Bacteroid on, provide
es spp.* glossitis stable
(including B. , urine solutions
fragilis*). retentio for the
n, time
dysuria, periods
edema, indicated in
facial the
swelling following
, table:
erythe (After the
ma, indicated
chills, time
tightnes periods,
s in any unused
throat, portions of
subster solutions
nal
 pain, should be
epistaxi discarded).
s and
mucosal
bleedin
g.

Para analg categorized used for the • caloric • an allergic • Nause - Check
ceta esic alongside treatment of undernutritio reaction, a, that the
mol and NSAIDs mild to n which can sudde patient is
antipy (nonsteroidal moderate • acute liver cause n not taking
retic anti- pain and failure a rash and weight any other
inflammatory reduction of • liver swelling loss, medication
drugs) due to its fever. problems • flushing, low loss of containing
ability to inhibit • a condition blood appetit paracetam
the Acetaminoph where the pressure and e ol.
cyclooxygenase en injection i body is a fast • Yellowi - For
(COX) s indicated unable to heartbeat – ng of children
pathways.14 It is for the maintain this can eyes who may
thought to exert management adequate sometimes and refuse
central actions of mild to blood flow happen when skin medicine
which ultimately moderate called shock paracetamol • Unexpl off a spoon
lead to the pain, the • acetaminoph is given in ained try using a
alleviation of management en overdose hospital into bruisin medicine
pain symptoms. of moderate • acute a vein in your g or syringe to
to severe inflammation arm bleedi squirt liquid
acetaminophen pain with of the liver • blood ng slowly into
increases the adjunctive due to disorders, • Difficul the side of
pain threshold by opioid hepatitis C such as ty in the child’s
inhibiting two analgesics, virus thrombocytop breathi mouth or
isoforms of and the enia (low ng use soluble
cyclooxygenase, reduction of number of • paracetam
COX-1 and COX- fever. platelet cells) ol mixed
2, which are and with a
involved in Because of leukopenia drink.
prostaglandin its low risk of (low number - Some
(PG) synthesis. causing of white children
Prostaglandins allergic blood cells) may be
are responsible reactions, • liver and happy to
for eliciting pain this drug can kidney take one
sensations. be damage, if paracetam
administered you take too ol product
in patients much but dislike
who are (overdose) – the taste of
intolerant to this can be another.
salicylates fatal in - There are
and those severe cases no known
with allergic harmful
tendencies, effects
including when used
bronchial during
asthmatics. S pregnancy.
pecific dosing - Small
guidelines amounts
 should be may pass
followed into breast
when milk.
administering However,
acetaminoph there are
en to children no known
harmful
effects
when used
by
breastfeedi
ng
mothers.
- Alcohol
increases
the risk of
liver
damage
that can
occur if an
overdose
of
paracetam
ol is taken.
The
hazards of
paracetam
ol overdose
are greater
in
persistent
heavy
drinkers
and in
people with
alcoholic
liver
disease.
- Evaluate
therapeutic
response
Meth ergot Methylergometri For the • blockage or • Abdominal • Blood can cause
ergin alkaloi ne acts directly prevention narrowing pain in the hypertensio
e ds on the smooth and control of mitral • headache urine n, cramps,
muscle of the of excessive heart valve • increased • chan nausea,
uterus and bleeding • high blood blood ge in vomiting,
increases the following pressure pressure skin dyspnea
tone, rate, and vaginal • a heart color • monitor
amplitude of childbirth attack • chest BP, heart
rhythmic • coronary pain rate,
contractions artery or uterine
through binding disease disco response
and the resultant • a stroke mfort • assess
antagonism of calcium
the dopamine D1 • a blockage • diffic levels –
receptor. Thus, it of the ult or effectivene
induces a rapid arteries labor ss ↓ with
and sustained called ed hypocalce
tetanic arterioscler breat mia
uterotonic effect osis hing • monitor
which shortens obliterans • diffic uterine
the third stage of • serious ulty bleeding
labor and numbness with and notify
reduces blood or prickling swall physician
loss. or tingling owin of any
of fingers g changes
and toes • dizzin Mothers
• liver ess should not
problems • fast, breast-feed
• decreased poun during
kidney ding, treatment
function or with
• seizures irreg Methergine
• pregnancy ular and at
• sepsis heart least 12
beat hours after
or administrati
pulse on of the
• hives last dose.
• lighth Milk
eade secreted
dness during this
, period
dizzin should be
ess, discarded.
or
fainti
ng
• pain
or
disco
mfort
in the
arms,
jaw,
back,
or
neck
• pain,
tende
rness
, or
swelli
ng of
the
foot
or leg
 • puffin
ess
or
swelli
ng of
the
eyelid
s or
aroun
d the
eyes,
face,
lips,
or
tongu
e
• slow
or
fast
heart
beat
• skin
rash
• swea
ting
• vomit
ing
Oxyt oxyto Oxytocin increas Administratio• Significant • Slow heart rate • rash can cause
ocin cic es the sodium n of cephalopelvic• Fast heart rate • hives ICH in
hormo permeability of exogenous disproportion• Premature vent • itching fetus
nes uterine oxytocin is • Unfavorable ricular complex • difficul • can cause
myofibrils, indicated in fetal positions es and other ty asphyxia in
indirectly the or irregular breathi fetus
stimulating antepartum presentations heartbeats ng or • may
contraction of period to , (arrhythmias) swallo cause
the uterine initiate or e.g., transver• Permanent cen wing coma and
smooth muscle. improve se lies, which tral nervous • swellin seizures in
The uterus uterine are system (CNS) g of mother
responds to contractions undeliverable or brain the • may
oxytocin more for vaginal without damage, and face, cause
readily in the delivery in conversion death throat, painful
presence of high situations before secondary to tongue contraction
estrogen where there delivery suffocation , lips, s
concentrations is fetal or • Obstetric • Neonatal seizur eyes, • assess
and with the maternal emergencies e hands, fetus
increased concern. For that favor • Neonatal feet, • assess
duration of example, It surgery yellowing of ankles, contraction
pregnancy. may be used• Fetal skin or eyes or s
to induce distress wher (jaundice) lower • monitor
labor in cases e delivery is • Fetal death legs blood
of Rh not imminent• Low Apgar • fast pressure
sensitization,• Where score (5 heartb • assess
maternal adequate minutes) eat maternal
diabetes, uterine electrolytes
preeclampsia activity fails • Uteroplacental • unusu • may
at or near to achieve hypoperfusion al cause
term, and satisfactory and variable bleedi uterine
when progress deceleration of ng tetany
delivery is • Hyperactive fetal heart rate
indicated due or hypertonic• Inadequate
to uterus fetal oxygen
prematurely • Contraindicat levels
ruptured ed vaginal (hypoxia)
membranes.I delivery, e.g.,• Perinatal hepat
mportantly, invasive cervi ic necrosis
oxytocin is cal carcinoma• Fetal hypercap
not approved , nia
or indicated active herpes• Severe
for elective genitalis, decreases in
induction of total placenta maternal systol
labor. previa, vasa ic and diastolic
Oxytocin may previa, blood pressure,
be used to and cord pres increases in
reinforce entation or heart rate,
labor in prolapse of systemic
select cases cord venous return
of uterine • Hypersensitivi and cardiac
inertia and as ty output,
adjunctive • Fetal and arrhythmia
therapy in distress, poly
the hydramnios,
management partial
of incomplete placenta
or inevitable previa, prema
abortion. In turity,
the borderline
postpartum cephalopelvic
period, disproportion,
oxytocin may previous
be used to major surgery
induced of cervix or
contractions uterus
in the 3rd (including C-
stage of labor section),
and to over-
control distension of
postpartum the uterus,
bleeding or grand
hemorrhage. multiparity,
invasive
cervical
carcinoma,
history of
uterine sepsis
, or traumatic
delivery
• Hyperstimulat
ion of the
 uterus, with
strong
(hypertonic)
and/or
prolonged
(tetanic)
contractions,
or a resting
uterine tone
of 15-20
mm H2O bet
ween
contractions
may occur,
possibly
resulting
in uterine
rupture,
cervical and
vaginal
lacerations,
postpartum
hemorrhage,
abruptio plac
entae,
impaired
uterine blood
flow, amniotic
fluid embolis
m, &
fetal trauma i
ncluding
intracranial
hemorrhage
• Not indicated
for elective
labor
induction

Seno stimul Sennosides are • Simple • Presence of Stomach/abdo • altered • Reduce

kot ant laxatives that (self- undiagnose minal pain or bowel dose in
laxativ work by induced or d acute or cramping, naus habit, patients
es stimulating the environmen persistent ea, diarrhea, nausea who
normal muscle tal). abdominal or weakness. and experien
contractions of • Constipatio symptoms may cause your vomitin ce
the colon. This n of old such as urine to turn g, weig consider
helps to age. cramps, reddish-brown. ht loss, able
coordinate the • Constipatio colic, nause steator abdomin
colon to be able n of a and rhoea, al
to evacuate pregnancy. vomiting, p malabs cramping
faeces • Constipatio ain or other orption .
effectively, and n due to symptoms , • Be aware
treat slow of appendici cathart that drug
constipation. passage tis. ic may
Senokot has the through the colon alter
ability to be colon (of and urine
transported unknown electrol and
through the rest origin). yte feces
of the • Irritable disturb color;
gastrointestinal bowel ances. yellowish
tract to the colon syndrome. brown
unchanged, so it • Constipatio (acid),
has no effect on n secondary reddish
the movements to other brown
of the stomach causes. (alkaline)
and small .
intestine. • Continue
d use
may lead
to
depende
nce.
Consult
physician
if
constipat
ion
persists.
• See
bisacodyl
for
additiona
l nursing
implicati
ons.
• Do not
breast
feed
while
taking
this
drug.

--- France Llana C. Cadag

BSN 2F