Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Blocks the Treatment and • known allergy to • CNS: Before:
final step of maintenance of either the drug or Headache,  Assess for history of
acid erosive the drug dizziness, vertigo, allergy to a proton
Prilosec production, esophagitis, components insomnia. pump inhibitor to
lowering the treatment of reduce the risk of
acid levels in heartburn • GI: Diarrhea,
Generic
hypersensitivity
the stomach associated with abdominal pain,
Name: and inhibits reaction
GERD. nausea, vomiting.
the hydrogen-  Monitor vital signs to
potassium Treatment of • Respiratory: establish baseline data
Omeprazole adenosine GERD, severe Upper respiratory  Inspect and palpate
triphosphate erosive infections, cough. the abdomen to
enzyme esophagitis, determine potential
Classification system on the • Skin: Rash
duodenal underlying medical
s: secretory ulcers, and conditions
surface of the
pathological
gastric
Proton Pump parietal cells.
hypersecretory During:
Inhibitors condition.  Administer drug
Treatment of
before meals to ensure
gastric ulcer.
that the patient
Dosage/ swallowed the capsule
Frequency/
whole to ensure the
Route:
therapeutic
effectiveness of the
40 mg/ OD drug.
before meal/  Monitor the patient’s
Oral nutritional status; use
of small frequent
meals may be helpful
Sources:
if GI upset is a
https:// problem.
nurseslabs.co
m/proton-
After:
pump-
inhibitors/  Monitor patient
response to the drug
 Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility
name of Action
Brand Name: Potassium is (1) Treat • Severe renal • CNS: Dizziness, Before:
readily and hypokalemia function mental confusion.  Note any impaired
rapidly due to digitalis impairment with • CV: renal function. Assess
K-Lyte absorbed intoxication, azotemia or Arrhythmias; for adequate urinary
from the GI diabetic oliguria, weak, irregular flow before
tract. Though acidosis,
Generic
pulse; administering
a number of diarrhea and • hyperkalemia
Name: salts can be hypotension, heart potassium. Impaired
vomiting, from any cause
used to block, ECG function can lead to
familial • anuria, heat abnormalities, hyperkalemia.
supply the
periodic cardiac arrest.
Potassium potassium cramps, acute  Monitor vital signs
Chloride cation, paralysis,
dehydration, and I&O to establish
potassium certain cases of • GI: Abdominal
baseline data
chloride is uremia, • severe hemolytic distention,
Classification the agent of hyperadrenalis reactions anorexia, N&V.
s: During:
choice since m, starvation
• clients receiving • Neuromuscular:  Provide glass of water
hypochloremi and debilitation,
potassium-sparing Weakness, upon administration
a frequently and
Electrolyte accompanies diuretics or paresthesia of  Withhold and report if
corticosteroid
potassium or diuretic aldosterone- extremities, abdominal pain,
deficiency. therapy. inhibiting drugs. flaccid paralysis, distention, or GI
Dosage/ areflexia, muscle bleeding occurs.
Frequency/ (2) Prophylaxis • Solid dosage or respiratory
Route:  Observe for S&S of
of potassium forms in clients in paralysis,
adrenal insufficiency
depletion when whom there is a weakness, and or extensive tissue
dietary intake is reason for delay or heaviness of legs.
600 mg/tab / breakdown.
not adequate arrest in passage
2 tabs TID /
Oral of tablets through • Miscellaneous:
Malaise. After:
the GI tract.
 Monitor patient
Sources:
response to the drug
 Monitor serum
2007 Edition potassium level
PDR Nurse’s
Drug
 Report S&S of
Handbook by hyperkalemia
Spratto, G. &
Woods, A.

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: The decreased Trimetazidine is • Severe renal • Nausea, Before:
 intracellular a piperazine function vomiting
pH and derivative impairment  Check for doctor’s
Trimetazidine
increased indicated for the • Abdominal pain,
concentration
order
symptomatic • known allergy to indigestion
of protons  Monitor vital signs to
Generic treatment of either the drug or
activates • Diarrhea establish baseline data
Name: sodium- stable angina the drug
hydrogen and pectoris in components • Dizziness
During:
sodium- patients
Trimetazidine calcium inadequately
• Parkinson’s • Headache  Administer
antiport disease, tremors, medication after meals
systems,
controlled or
restless leg • Feeling weak
intolerant to  Provide glass of water
Classification raising syndrome or other • Rashes
first line upon administration
intracellular
s: related movement  Observe for
calcium therapies
concentrations disorders prescribing signs of
fatty acid
, finally heart failure such as
leading to swelling of hands and
oxidation
decreased
inhibitors
contractility.
feet or SOB.

After:
Dosage/  Monitor patient
Frequency/
response to the drug
Route:
 Advise patient of the
adverse effects of the
35 mg/ BID / drug
Oral

Sources:
https://
www.healthhub
.sg/a-z/
medications/
trimetazidine

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Decreases (1) Control of • Contraindicated • CNS: agitation, Before:
fever by a pain due to in patient with anxiety, headache,  Assess overall health
hypothalamic headache, hypersensitivity to fatigue, insomnia status and alcohol
Naprex effect leading earache, drug. usage before
to sweating dysmenorrhea, • CV:
administering
and arthralgia, • Use cautiously in hypertension,
Generic vasodilation.  Monitor vital signs to
myalgia, patients with long-
Name: Also inhibits musculoskeletal term alcohol use hypotension establish baseline data
the effect of pain, arthritis, because
pyrogens on immunizations, c• Hemat:
therapeutic doses During:
Paracetamol the teething, neutropenia,
cause  Assess fever; note the
hypothalamic tonsillectomy. pancytopenia
hepatotoxicity in presence of associated
heat-
Classification (2) To reduce these patients. • Resp: signs (diaphoresis,
regulating
s: centers. fever in atelectasis, tachycardia, and
• Individuals with
bacterial or dyspnea malaise).
liver or kidney
viral infections.  Withdraw the
disease • GI:
Non opioids appropriate dose from
analgesics hepatotoxicity,
• Used with the vial and place it in
and constipation,
antipyretics
caution in people a separate empty,
increased liver
with a history of sterile container for IV
enzymes, nausea,
allergies, asthma, infusions.
vomiting
Dosage/ or other breathing  Monitor the end of
Frequency/ problems • MS: muscle infusion in order to
Route: spasms, trismus prevent air embolism
• Skin: rash,
After:
300 mg / q4h urticaria, itching,
PRN / IVTT  Monitor patient
hives
response to the drug

Sources:

2007 Edition
PDR Nurse’s
Drug
Handbook by
Spratto, G. &
Woods, A.

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Possible (1) • Contraindicated • CNS: Headache, Before:
slight Hypertension in patient with fatigue, lethargy,  Assess for the
decrease in alone or in hypersensitivity to dizziness, mentioned
Norvasc myocardial combination lightheaded-ness,
drug. contraindications to
contractility. with other sleep disturbances.
this drug to prevent
CO is antihypertensive • Use with
Generic increased;
• GI: irritations, potential adverse
s. grapefruit juice.
Name: ulcer, constipation, effects.
moderate
• Use with caution liver injury  Monitor vital signs to
decrease in (2) Chronic
peripheral stable angina in clients with • CV: reflex
Amlodipine vascular alone or in CHF and in those tachycardia, chest establish baseline data
resistance. combination with impaired pain, heart failure,
with other hepatic function or cardiac arrhythmias During:
Classification antianginal
s:
reduced hepatic • Dermatologic:  Administer drug on
drugs. blood flow. rash, alopecia, empty stomach one
dermatitis, hour before or two
• Hyponatremia
Calcium photosensitivity hours after meal to
and hypovolemia
Channel
• GU: renal ensure optimum drug
Blocker absorption
insufficiency, renal
failure, proteinuria  Monitor renal and
hepatic function tests
Dosage/
Frequency/ for possible
Route: development of renal
and/or hepatic failure
as well as to signal
10 mg/ OD / need for reduced drug
Oral dose.

After:
Sources:
 Monitor patient
2007 Edition response to therapy
PDR Nurse’s
through blood
Drug
Handbook by pressure monitoring.
Spratto, G. &  Monitor patient
Woods, A. compliance to drug
therapy.

Drug Mechanism Indication Contraindications Side Effects Nursing Responsibility

name of Action
Brand Name: Has both (1) Essential • Contraindicated • CNS: dizziness, Before:
alpha- and hypertension in patient with paresthesias,  Assess for
beta- used either hypersensitivity to insomnia, contraindications or
Coreg adrenergic alone or in depression, fatigue,
drug. cautions to prevent
blocking combination vertigo
potential adverse
activity. with other • Clients with
Generic Decreases
• CV: arrhythmias, effects.
antihypertensive NYHA Class IV
Name: cardiac
hypotension, heart  Monitor vital signs to
drugs, decompensated failure, pulmonary
output, establish baseline data
especially cardiac failure, edema, CVA
reduces to monitor for any
thiazide bronchial asthma,
Carvedilol exercise- or • GI: nausea, potential adverse
diuretics. or related
isoproterenol vomiting, diarrhea, effects.
-induced
bronchospastic
Classification tachycardia, (2) Mild to conditions anorexia, flatulence
s: reduces reflex severe heart During:
• Client with • Respi:
orthostatic failure of  Provide glass of water
hepatic bronchospasms,
hypotension, ischemic or upon administration
Alpha-beta impairment cough, rhinitis,
causes cardiomyopathi
Adrenergic bronchial  Provide patient
vasodilation, c origin; used
Blocking and reduces • Use with caution obstruction education about drug
Agent with diuretics, in hypertensive effects and warning
peripheral • GU: decreased
ACE inhibitors, clients with CHF signs to report to
vascular libido, impotence,
and digitalis to controlled with enhance knowledge
resistance. dysuria, Peyronie
Dosage/ increase
digitalis, diuretics, disease about drug therapy
Frequency/ survival and
Route: or an ACE and promote
reduce risk of
inhibitor compliance
hospitalization.

6.25 mg/ half After:

tab/ BID /  Monitor patient
Oral
response to therapy
through blood
Sources:
pressure monitoring.
 Monitor patient
2007 Edition compliance to drug
PDR Nurse’s
Drug
therapy.
Handbook by
Spratto, G. &
Woods, A.