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Attempt all questions.
The number of marks is given in brackets [ ] at the end or part of each question.
This document consists of 18 printed pages excluding the front page.
Total Marks
Marks Obtained
___________________
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(20 marks)
1. Which diagram shows the human double circulatory system?
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3. The diagram shows the heart as seen from the front.
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4. What is the characteristic feature of a double circulation?
A In each circuit, blood passes from the gut to the liver before going back to the
heart.
B In each circuit, blood passes from the heart to the lungs and then back to the
heart before going to other parts of the body.
C In each circuit, blood passes through atria and ventricles before going to other
parts of the body.
D In each circuit, blood passes through the arteries and the capillaries before
returning to the heart in veins.
6. The diagram shows cross-sections of three types of blood vessel (not drawn to the
same scale).
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7. The photograph shows some blood as seen under the microscope.
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9. The table shows the percentage composition of three gases in atmospheric air.
In which order does blood pass through the chambers during a complete circuit of the
body after it returns from the lungs?
AQ→R→S→P
BQ→R→P→S
CP→S→Q→R
DP→S→R→Q
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11 An athlete takes part in a race. The graph shows her breathing rate before, during
and after the race.
At which point does her body contain the greatest amount of lactic acid?
13. The diagram shows human blood as seen through a light microscope. A person’s
blood is unable to clot. Which component of the blood is not functioning properly?
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14. What are the functions of the diaphragm and the cilia in the human gas exchange
system?
16. When blood is flowing through a vena cava, which main blood vessel will it flow
through next?
A hepatic portal vein
B hepatic vein
C pulmonary artery
D pulmonary vein
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18. Four word equations are shown.
P carbon dioxide + water → glucose + oxygen
Q glucose + oxygen → carbon dioxide + water
R glucose → lactic acid
S glucose → alcohol + carbon dioxide
What are the equations for anaerobic respiration in humans and anaerobic respiration in
yeast?
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(35 marks)
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(ii) Using information from Fig. 1.1, suggest how the mosquito is adapted for feeding on
human blood.
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(b) (i) The human body has a number of defences against disease.
State the name of the mechanical barrier which is broken by the mosquito.
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(ii) Some components of blood defend the body against disease.
Table 1.1 contains the names of three of the components of blood.
It also states three defence mechanisms.
Complete Table 1.1 by placing a tick () in the box that matches each defence
mechanism to the correct component of blood.
Table 1.1
1 .........................................................................................................................................
2 .....................................................................................................................................[2]
[Total: 9]
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2. Blood is distributed through the body of a mammal in blood vessels. The blood supply
to muscles changes considerably at the start and at the end of exercise.
Fig. 2.1 shows a cross section of a blood vessel as seen with an electron microscope.
Fig. 2.1
(a) Name:
(i) cell X;
....................................................................................................................... (1)
(ii) liquid Y;
........................................................................................................................ (1)
......................................................................................................................... (1)
(b) State three substances that move across the wall of the blood vessel at Z.
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.......................................................................................................................................(3)
[Total: 6]
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3. One role of nutrients is to provide materials for the repair of damaged tissues.
Fig. 3.1 shows the events that happen after a cut to the skin.
Fig. 3.1
Use the information in Fig. 3.1 to describe what happens to seal the wound in the skin
and repair the skin tissue.
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[Total: 5]
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4. Fig. 4.1 shows a vertical section of a human heart.
J..........................................................................................................................................
K.........................................................................................................................................
L..........................................................................................................................................
M....................................................................................................................................(4)
(b) Sensors that detect changes in blood pressure were placed into the blood vessels
surrounding the heart. Recordings were taken at the times when the ventricles contracted
and when they relaxed.
The blood pressures recorded are shown in Table 4.1.
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(i) Explain why the pressure in blood vessel J is greater than the pressure in blood vessel
M.
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(ii) Explain why the pressure in blood vessels K and L is much less than the pressure
in blood vessels J and M.
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(c) Explain how the valves at N and O maintain one-way flow of blood through the heart.
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[Total: 11]
5. Choose words from the list to complete the sentences about respiration.
Each word may be used once, more than once or not at all.
During exercise muscle cells can respire anaerobically and convert ...................................
to ............................................... .
When yeast cells respire anaerobically they produce ............................................... and
................................................ . [4]
[Total: 4]
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(15 marks)
1 A group of students investigated how their pulse rate changed during exercise.
They measured their resting pulse rate before they started exercising.
(a) (i) Describe how to measure pulse rate.
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……………......................................................................................................................................[2]
(ii) Explain why it is important to measure the resting pulse rate.
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(b) The students exercised for 1 minute and then measured their pulse rate.
They immediately exercised for another minute and measured their pulse rate again.
They continued exercising and measured their pulse rate every minute up to a total of 5 minutes.
Fig. 1.1 shows the results for one of the students.
Fig. 1.1
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(i) A table is drawn below for the results shown in Fig. 1.1.
Write the results in this table.
0 / resting
5
[1]
(ii) Describe the results and suggest an explanation for them.
description ..........................................................................................................................................
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explanation ........................................................................................................................................
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(c) Fig. 1.2 shows a cross-section of a human coronary artery as seen with a microscope.
Fig. 1.2
The actual internal diameter of this coronary artery at AB is 4.3 mm.
(i) Measure the length of AB in Fig. 1.2.
length of AB in Fig. 1.2 ........................................ mm
Calculate the magnification of Fig. 1.2.
Show your working.
1. AIDS: …………………………………………………….
2. Malaria: …………………………………………………
4. Cholera: ……………………………………….…………[4]
[Total: 15]
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