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DOI: 10.1111/jdv.

16925 JEADV

REVIEW ARTICLE

‘Occupational dermatoses from Personal Protective


Equipment during the COVID-19 pandemic in the
tropics – A Review’
H.C. Lee,1,* , C.L. Goh2
1
Dermatology Department, KK Women’s and Children’s Hospital, Singapore
2
National Skin Centre, Singapore
*Correspondence: H.C. Lee. E-mail: dermhclee@gmail.com

Abstract
The COVID-19 pandemic has enveloped the world and there has been a high incidence of occupational dermatoses
related to Personal Protective Equipment (PPE) amongst healthcare workers (HCWs) during this period. Prevention and
management of these conditions will not only improve staff morale and quality of life, but will also minimize the risk of
breaching PPE protocol due to such symptoms. The tropical climate in Singapore predisposes HCWs to more skin dam-
age and pruritus due to intense heat, high humidity and sun exposure. The effects of friction, occlusion, hyperhidrosis
and overheating on the skin in the tropics should not be neglected. Preventive measures can be taken based on our rec-
ommendations, and the working environment can be made more conducive for frontline HCWs. We review the literature
and discuss various preventive and management strategies for these occupational skin diseases for our frontline HCWs,
especially those working in less controlled working environments beyond the hospital in Singapore. Shorter shifts and
frequent breaks from PPE are recommended. Duration of continuous PPE-usage should not exceed 6 h, with breaks in
non-contaminated areas every 2–3 h to hydrate and mitigate the risk of skin reactions. Other strategies, such as teleder-
matology, should be considered so that consultations can remain accessible, while ensuring the safety and well-being of
our clinical staff.
Received: 14 June 2020; Accepted: 21 August 2020

Conflict of Interest
None reported.

Funding Sources
None reported.

COVID-19 pandemic in Singapore Healthcare workers (HCWs) have been deployed across the
The first cluster of COVID-19 cases was reported in Wuhan, island to these facilities. Given the current evidence of how it is
China in Dec 2019. It was not long before the disease spread spread, these frontline HCWs require personal protection equip-
exponentially across the globe, and the World Health Organiza- ment (PPE) with respiratory droplet and contact precautions to
tion (WHO) eventually declared COVID-19 as a pandemic on mitigate the risk of viral transmission.
12 March 2020. Since then, this pandemic has resulted in more There is a high incidence of occupational skin disease from
than 19 million cases, with more than 12 million recoveries and PPE amongst HCWs.1,2 During the Severe Acute Respiratory
over 700 000 deaths globally. Syndrome (SARS) epidemic, PPE use was associated with high
Singapore confirmed its first imported case of COVID-19 rates of adverse skin reactions in HCWs in Singapore.3
from China on 23 Jan 2020. Local transmission became apparent To date, even higher incidences of PPE-related dermatoses
in February 2020, and by March, multiple COVID-19 clusters have been reported in the current COVID-19 pandemic.4–6 If
were identified in dormitories for foreign workers. To facilitate untreated, these occupational dermatoses and their symptoms
extensive ‘proactive’ screening and create more bed capacity for can affect PPE compliance and staff morale. They can also result
isolation and care of COVID-19 patients, Singapore has since in inadvertent PPE breaches or PPE failure due to symptoms or
ramped up operations in hospitals, worker dormitories, outdoor discomfort, putting HCWs at risk of COVID-19 transmission at
screening centres and community care and recovery facilities. work.7 Prevention, early recognition and prompt management

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
590 Lee and Goh

of these dermatoses are therefore critical to protect HCWs in


this pandemic.
Unfortunately, it is difficult for HCWs to get dermatology
consults given the current circumstances in COVID-19. Many
have anecdotally chosen to self-medicate or ignore their symp-
toms until they worsen.
Singapore lies near the equator and is well known for its
perennial high temperatures and humidity as is in most coun-
tries in the tropics. HCWs have been deployed, beyond hospitals,
to facilities with less controlled environments. The heat, humid-
ity and prolonged duration wearing PPE in these environments
can make HCWs vulnerable to various skin disorders and heat
stress. We review the literature and discuss strategies to prevent
and manage adverse skin reactions due to PPE in HCWs in trop-
ical climates like Singapore.
Figure 1 a & b. A HCW developing acne over bilateral cheeks
Skin reactions related to N95 Masks and Goggles after wearing N95 masks daily for 1 month.
During SARS in Singapore, 35.5% of staff using N95 masks reg-
ularly for an average duration of 8 h/day (mean period:
8.4 months) self-reported adverse skin reactions, including acne used before and after wearing masks. Topical antibiotics, BP
(59.6%), facial itch (51.4%) and rashes (35.8%).3 2.5% cream or gel or combination creams, can be used for acnei-
During the current COVID-19 pandemic, 97% of frontline form papules. Topical retinoids (e.g. adapalene cream or gel)
HCWs in China reported PPE-related skin reactions.4 Those can be used at night to treat comedones. These topicals should
who wore medical devices (N95 mask and goggles) longer than be used judiciously to avoid any risk of skin irritation. Lower
6 h had higher risks of skin damage in corresponding sites than concentration of retinoids may be preferable to minimize skin
those who did for a shorter duration. Wearing a face shield for a irritation. In addition, non-comedogenic, oil-free moisturizers
longer duration (>6 h) was not a significant risk factor in caus- are recommended when indicated. Dermatology consultation is
ing forehead skin damage. warranted in severe or recalcitrant cases where systemic antibi-
Prolonged usage of these facial protection devices is therefore otics may be needed.
a major predisposing factor for skin damage. On an administra-
tive level, it would be advisable to introduce more breaks where 2) Skin indentations and Pressure injuries (PIs)
feasible and shorten shifts to reduce the duration of continuous Healthcare workers wearing goggles and N95 masks have
PPE-usage to no more than 6 h, especially in the warm and reported skin indentations and mild erythema, even after 1–2 h.
humid climate in the tropics. Many HCWs have anecdotally neglected these early warning
signs of PIs. It is important to highlight that, with constant pres-
1) Acne sure to the same sites daily, indentations and erythema will pro-
For those with pre-existing acne vulgaris, repetitive pressure and gress to eventual PIs with blisters, erosions and ulcers. The nasal
friction from N95 masks and goggles can cause pilosebaceous bridge and cheeks are common sites of pressure.4 (Fig. 2a,b) The
ductal occlusion and aggravate pre-existing inflammatory tropical climate may exacerbate the hyperhydration effects of
papules.4 HCWs with no prior history of acne can develop acne excess moisture accumulated under N95 masks causing skin
mechanica, as mechanical trauma from the mask and goggles maceration. This increases the risk of skin damage and PIs in
can cause rupture of micro-comedones, resulting in inflamma- corresponding sites and can lead to secondary infections due to
tion. (Fig. 1) The mask and goggles also create a hot and humid micro-abrasions.
‘micro-climate’, resulting in excess sweat and sebum accumula- To prevent PIs, the first goal is to prepare the skin prior to
tion on the face.8 This promotes bacterial growth (Propionibac- donning PPE.10 We recommend gentle pH-balanced face cleans-
terium acnes) and creates an ideal environment for acne. The ers, and avoiding the use of alkaline soaps or cleansers that dam-
tropical climate in Singapore has high humidity, high tempera- age the skin barrier. After patting the face dry, a liquid skin
ture and sun exposure, all of which have been reported to exac- sealant (e.g. silicone gels, 3MTMCavilonTM No Sting Barrier
erbate acne.9 Film) can be applied over potential sites of pressure. Avoid
We recommend that HCWs take regular breaks to minimize applying these skin protectants near the eyes and mucous mem-
the friction and pressure from these devices. Facial cleansers branes. Rub them gently into the skin and ensure the skin is fully
containing salicylic acid (SA) and benzoyl peroxide (BP) can be dry before donning PPE.

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
Occupational Dermatoses from PPE during COVID-19 (Review) 591

If significant PIs develop from goggles, face shields or visors


can be considered.

3) Contact and Delayed Pressure Urticaria


Well-fitted N95 masks and goggles create a tight seal on facial
skin. These devices, along with their accompanying straps, can
cause contact or delayed pressure urticaria.6,15 We encourage
HCWs to take regular breaks every 2 to 3 h to minimize the
pressure and friction from these PPE. We recommend prophy-
lactic non-sedating oral antihistamines 1–2 h prior to the shift
duty.

4) Cheilitis
Lip licker’s dermatitis or cheilitis has been reported in frontline
HCWs.16 This has been attributed to frequent licking of lips due
to dehydration and reduced fluid intake, which can be exacer-
Figure 2 (a) A painful pressure erosion over the nasal bridge due
bated in hot and humid climates. We recommend regular appli-
to N95 masks after 2 weeks. (b) Skin indentations on the cheeks
due to N95 masks, and an attempt to apply prophylactic hydrocol- cation of lipid-bearing fragrance-free lip balms and regular
loid dressings on the nasal bridge to prevent pressure injuries. hydration every 2–3 h during breaks in non-contaminated areas.
Mask refitting was advised.
5) Other skin reactions
Petrolatum-based products or oils are not recommended in Facial pigmentation has been reported by HCWs. It is likely to
view of the possibility of promoting mask slippage and compro- be due to post-inflammatory hyperpigmentation or rarely, from
mising the integrity and fit of the mask.10,11 Thick dressings are pigmented contact dermatitis (CD).3 Other facial PPE-related
also discouraged as these will increase the intensity of pressure dermatoses include seborrhoeic dermatitis, frictional dermatitis
on the skin and compromise the mask fit.10 and irritant contact dermatitis (ICD). Frictional dermatitis and
To minimize the pressure intensity, thin prophylactic dress- ICD can be caused by the mask or goggle linings and their
ings have been suggested.6,12,13 This is controversial as there is accompanying straps. Hyperhydration effects from the environ-
currently no evidence to ensure that dressings will not compro- mental heat and humidity can exacerbate these facial protection
mise the wearer’s safety from COVID-19.10 If thin dressings device-related dermatoses.
instead of the above recommendations have to be used, we The straps of facial protection devices, including N95 masks,
strongly recommend doing seal checks and mask refitting as pre- can also cause abrasions or ICD on the external ear, especially
cautionary measures. While this may be limited by time and the root of the auricular helix.13 To prevent the latter, Lee et al
supply constraints, the safety of frontline HCWs is paramount. proposed a new design of respiratory masks with a dually split
Two HCWs were infected with Ebola virus due to incorrect PPE head strap and a neck strap that avoids contact over the external
use or PPE failure.14 It will be useful to obtain more definitive ear.17 While ear-independent masks is an option, another rec-
data regarding successful mask refitting of N95 masks with thin ommendation is to cover these areas with the surgical cap before
prophylactic hydrocolloid dressing. wearing the ear-dependent PPE,16 to minimize pressure from
The second goal is to relieve pressure by minimizing the dura- the straps.
tion of pressure.10 HCWs should take frequent breaks of about Rarely, allergic contact dermatitis (ACD) due to mask com-
10–15 min (in non-contaminated areas) to remove the devices ponents such as metal clips, rubber straps or adhesives in
from the face every 2 to 3 h. It is also important to wash hands these PPE devices can occur. Cases of ACD to thiuram in the
before and after touching the mask. elastic straps of masks and rubber compounding materials
Lipid or ceramide-based moisturizers should be applied at such as carba mix and acrylates in mask adhesives have been
least 1 h before donning PPE. When no longer on duty, it is reported.18–20 Dibromodicyanobutane, found in the adhesives
important to moisturize the face regularly to maintain skin bar- of surgical face masks, has also been reported to cause ACD
rier integrity. in a HCW.19 In terms of textile ACD, two HCWs developed
If significant PIs are present, HCWs should seek medical ACD to free formaldehyde and formaldehyde-releasing agents
advice. Wound dressings can be prescribed depending on the found in the N95 masks during the SARS period.21 If occupa-
nature of the wound. Ideally, skin injuries should be allowed to tional-related ACD is suspected, patch and skin prick tests
heal before resuming the PPE mask. Topical antibiotics can be may be required and if confirmed, appropriate substitution
applied to micro-abrasions with secondary infections. becomes necessary.

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
592 Lee and Goh

Topical steroids can be applied to inflamed areas, and regular as the top 5 allergens in a review of health care hand sanitizers.41
emollients will help to protect the skin barrier from further dam- Patch tests can be done, and in the evaluation of isopropanol
age. Skin protectants such as silicone gel can be used to mini- allergy, this should be done with a dilution of 10% isopropanol, as
mize friction. All topicals should be applied at least 1 h before 100% isopropanol in an occlusive patch test can possibly cause
donning PPE. toxic skin reactions that may be misinterpreted as a true allergy.39
With regard to alcohol-free hand rubs, these may contain a
Skin reactions related to hand hygiene and gloves quaternary ammonium compound known as benzalkonium
chloride (BAC). While it has been approved for the formulation
1) Hand hygiene and irritant hand dermatitis of hand rubs for HCWs, there is still limited data on the efficacy
Hand hygiene is critical for the prevention of viral transmission. of BAC against certain bacteria and viruses compared to that of
However, the importance of rational hand hygiene needs to be AHBRs.26,42 Furthermore, BAC is a well-known irritant, and in
emphasized to all frontline HCWs.22 Overzealous hand hygiene some cases, a contact allergen.43,44 Found in many disinfectants
without regular hand protection and skin barrier repair will lead in the healthcare setting, it should also be considered in evalua-
to skin damage, creating a potential route of entry for COVID- tion of occupational contact dermatitis in HCWs, especially dur-
19. Hand hygiene exposes the skin to friction, rubbing, water, ing this pandemic.45
surfactants and defatting chemicals which will compromise the
skin barrier, alter the hands’ microbial flora and cause ICD.23,24 2) Glove-related skin reactions
84.6% of HCWs reported the hands as the most common site
affected in terms of PPE-related dermatoses.5 Majority washed Irritant contact dermatitis (ICD) Irritant contact dermatitis is
their hands more than 10 times/day, but only 22.1% applied the most common skin reaction to wearing medical gloves
emollients after washing. amongst HCWs. It is caused by the occlusive effects of gloves,
Alcohol-based hand rubs (ABHR) (>60% ethanol or 70% iso- glove powder, soaps and incomplete hand drying before don-
propanol) are recommended for HCWs and preferred to soap ning gloves. (Fig. 3).
and water unless there is visible soilage.25,26 ABHRs have been Double gloving has been reported to reduce the risk of viral
shown to inactivate the virus, are more convenient and improve contamination during PPE removal.46 12.4% of HCWs reported
compliance to hand hygiene amongst HCWs.25,26 They are also wearing three layers of gloves during shifts.6 We do not recom-
known to cause less skin damage than hand washing, and gel mend this for everyone, especially in the hot and humid climate
formulations have been shown to be better tolerated than liquid in the tropics. Prolonged occlusion and hyperhydration which
formulations.27 Hand hygiene practices must be followed by skin lead to skin maceration will compromise the skin barrier, mak-
barrier repair through the judicious application of skin moistur- ing the skin more vulnerable to irritation due to components of
izers.28 Application of emollients will not compromise the effi- the medical gloves. A single layer of latex gloves is adequate for
cacy of ABHRs and ceramide-containing moisturizers are skin protection.5 An additional layer of gloves can be considered
recommended.29 Accessories such as rings should not be worn at in special circumstances where there is a potential breach in
work as irritants and chemicals may accumulate underneath
them during zealous hand hygiene practices.30
Topical corticosteroids and antibiotics are indicated for those
with clinical ICD and secondary infections respectively. More
importantly, the damaged skin should be given time even after
clinical clearance of skin inflammation, to recover fully before
resuming duties.
True allergic reactions to alcohol-based formulations are
uncommon.28 A HCW developed suspected ACD to iodopropynyl
butylcarbamate, found in a common brand of ABHRs.31 Cases of
ACD to isopropanol have been reported.32–38 A case series of 44
patients with positive patch tests to isopropanol revealed an 84%
relevance rate, and the authors suggested that sensitization to iso-
propanol is not that uncommon.38 However, it has been postu-
lated that these positive patch tests reactions are more likely toxic
skin reactions to 100% isopropanol rather than true allergic reac-
tions.39 Most other allergic reactions, if ever, are caused by other Figure 3 Irritant contact dermatitis over the fingers in a HCW after
frequent hand washing and prolonged duration of wearing medical
excipients or preservatives in the ABHR.40 Tocopherol, fragrance, gloves after a few weeks.
propylene glycol, benzoates and cetyl stearyl alcohol were revealed

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
Occupational Dermatoses from PPE during COVID-19 (Review) 593

hand PPE in the presence of pre-existing skin damage, heavy soi- mean annual relative humidity of 83.9% predispose our front-
lage or torn gloves. line HCWs to skin reactions, maceration and skin barrier func-
tion damage.
ACD to rubber chemicals (Type IV hypersensitivity reaction) Elston highlighted how common skin reactions could impact
and True Latex Allergy (Type I hypersensitivity reaction) Latex an effective workforce in times of crises, citing the significant
products composed of chemical accelerators and natural rubber reduction in military power because of skin diseases in tropical
latex proteins (NRL) can cause glove-related occupational aller- Vietnam as a historical example.1
gic skin reactions. Heat injuries and thermal strain are occupational hazards that
Contact allergy to rubber additives in medical gloves is the should not be overlooked in HCWs working in the tropics.
most common cause of occupational allergic hand dermatitis in Overheating has been commonly reported with all forms of PPE
HCWs.47 These Type IV delayed hypersensitivity reactions are amongst HCWs.52
caused by chemical accelerators such as thiuram and carbamates Humidity, dust, increased temperatures and sun exposure are
and present as ACD. Patch testing is required for diagnosis. known to increase the risk of skin inflammation such as atopic
‘True Latex allergy’, or immediate type I hypersensitivity reac- dermatitis (AD).53–56 High humidity and heat result in excess
tions to NRL can present with a spectrum of clinical manifesta- moisture accumulation on the skin protected by PPE, leading to
tions ranging from contact urticaria to potentially life- epidermal barrier disruption, inflammation and potential infec-
threatening anaphylaxis.48 The prevalence rate of latex sensitiza- tions.
tion of 9.6% was reported amongst HCWs in Singapore.49 NRLs New-onset dermatitis or flares of pre-existing inflammatory
present in the powder in medical gloves can be potential aeroal- skin conditions like eczema and psoriasis can therefore present
lergens, causing a systemic allergic reaction in latex-sensitive in HCWs due to PPE. Profuse sweating, occlusive clothing, syn-
individuals.50 Skin prick tests remain the gold standard for diag- thetic non-absorbent clothing and friction are exacerbating fac-
nosing type 1 latex allergy and should be done in the clinic or tors for sweat-induced dermatitis, widely described in tropical
hospital setting with necessary medical staff and latex-free resus- climates.57–59 (Fig. 4).
citation equipment available. Hyperhidrosis itself has been known to worsen pruritus and
While patch and skin prick tests remain the gold standard for cause skin irritation.55,60,61 The acidic pH of sweat promotes
evaluation of ACD to rubber additives and latex allergy respec- Th2 and Th17-mediated inflammation, with subsequent down-
tively, these may not be feasible or easily accessible during this regulation of filaggrin expression.62 Higher temperatures induce
ongoing pandemic. The use of non-powdered, reduced protein cutaneous vasodilatation and stimulation of C nerve fibres, caus-
and low-allergen latex gloves by all workers, and non-latex ing pruritus.62 Malassezia globosa has been found to be respon-
gloves by sensitized individuals can decrease the rate of sensitiza- sible for producing the main histamine-releasing antigen in
tion in high-risk groups such as HCWs and reduce the rate of human sweat, exacerbating cholinergic urticaria and AD.63 Dis-
NRL allergic reactions in sensitized groups.48,51 During SARS, comfort from hyperhidrosis will also affect PPE compliance and
some HCWs improved after changing to latex-free gloves (nitrile can cause ICD over the areas covered by PPE.6 Any area covered
or vinyl), non-powdered latex gloves and wearing plastic or cot-
ton gloves beneath the latex gloves.3 These temporary measures
can be adopted until a review with a dermatology or occupa-
tional health clinic is available.
In the event of any of these skin reactions, topical steroids are
warranted for inflammation, and intensive emollients for skin
barrier repair. When using lipid-bearing emollients or barrier
creams on the hands, it is prudent to do this at least 1 h before
shift. HCWs should ensure the hands are completely dry before
donning PPE to avoid hyperhydration or occlusion that will pre-
cipitate skin damage. Avoid oil or petroleum-based hand creams
as they can cause glove deterioration. One must also remember
that contact allergy to constituents of emollients and barrier
repair cream may also occur.

Effects of tropical climate on the skin and gown-


related skin reactions Figure 4 Eczema flare over the neck exacerbated by perspiration
and friction from the disposable gown in an outdoor screening
The high ambient temperatures in Singapore which range from centre.
23–25°C (night) to 31–33°C (daytime) throughout the year and

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
594 Lee and Goh

Presence of facial hair can predispose one to mask-related


dermatoses such as acne, folliculitis and ICD. Thick facial hair
may compromise the fit and integrity of N95 masks.64,65 Regular
shaving and cleansing are advised.

Conclusion
The safety of HCWs should not be compromised, and by pre-
venting PPE-related dermatoses, we also maintain the integrity
of PPE and its protective nature to mitigate the transmission of
COVID-19.
It is important to have comprehensive guidelines on pre-
vention and management of PPE-related dermatoses in
Figure 5 (a) Flare of sebopsoriasis over the occiput exacerbated HCWs. The recommendations must also take into considera-
by perspiration and occlusion under the surgical cap. (b) Intertrigo tion the environmental factors and conditions at the sites of
in the toe webspaces after 1 month of working in a hot and humid
deployment for HCWs. While climate factors such as temper-
environment. The HCW self-medicated with no improvement,
eventually requiring a formal dermatology consult. ature, humidity and sun exposure are non-modifiable, other
methods can be adopted to make the environment more con-
ducive for frontline HCWs. Prolonged use of PPE due to
by PPE is therefore vulnerable to hyperhydration effects, from long shift duties are a major risk factor for these skin reac-
the scalp to the toes. (Fig. 5a,b). tions. We recommend shifts of about 5-6 h, with mandatory
Surgical caps can cause itch, folliculitis and aggravate sebor- breaks every 2–3 h to allow relief of pressure from facial pro-
rhoeic dermatitis. The high ambient temperature and humidity tection devices where possible and to mitigate the risks of
in tropical countries including Singapore also predisposes indi- other adverse skin reactions as discussed. HCWs should be
viduals to skin conditions such as miliaria, cholinergic urticaria reminded to hydrate themselves as frequently as possible. Rest
and superficial fungal infections. areas in non-contaminated areas should be made easily acces-
Free formaldehyde and formaldehyde textile resins (FTR) sible for HCWs, with good ventilation and cooling devices.
may be present in hospital uniforms and non-woven fabric in While we have provided recommendations on prevention and
disposable gowns and masks. These can all cause textile ACD in management, severe or intractable cases should still seek advice
HCWs, which can be exacerbated by friction, heat, moisture from a dermatologist. Occupational skin diseases, including
accumulation due to perspiration, and restrictive or occlusive occupational allergic skin reactions, have a significant impact on
clothing. A HCW was found to have textile ACD to FTRs in N95 HCWs and must not be neglected. Contact dermatitis and occu-
masks and scrubs during the SARS epidemic.21 pational dermatology clinics should remain operational during
Healthcare workers should be given frequent breaks to hydrate the time of the pandemic to cater to the needs of our frontline
themselves during work. It is recommended that they wear thin, HCWs. The benefits of ‘virtual’ occupational skin health clinics
cool, moisture-wicking garments beneath the PPE gowns to miti- for HCWs during this pandemic have been discussed.66 While
gate the heat and humidity. Non-contaminated areas where we have highlighted the importance of making ourselves avail-
HCWs take breaks should be well ventilated with cooling devices able to our patients and the community via teledermatology
available. Non-sedating antihistamines can be taken for cholinergic during this period, we should not forget fellow HCWs working
urticaria or intense pruritus. Mild topical steroids and topical anti- on the frontline. Physical or teledermatology consultations can
fungals can be used for miliaria and superficial fungal infections be made more accessible to all frontline HCWs, especially those
respectively. Flares of AD, CD, psoriasis and seborrhoeic dermati- with pre-existing skin conditions prior to the pandemic. Special
tis should be managed with topical steroids, emollients and trigger arrangements can be made to accommodate frontline HCWs
avoidance. Patch tests should be done if textile ACD is suspected. and their variable working hours.
To protect the skin barrier, we recommend gentle soap-free It is important to remember that the fight against the
cleansers, and regular application of moisturizers before and COVID-19 pandemic is not only a nationwide effort for each
after shifts and as frequently as possible when at home, especially country, but that of a global one. More definitive data on pre-
after showering. vention strategies for PPE-related dermatoses will help in the
For practical reasons, scalp hair should be kept short to facili- current fight, if not the future.
tate adequate protection by surgical caps to avoid hair contami-
nation. This also allows easy decontamination and cleansing. It Acknowledgement
also reduces the chance of moisture accumulation and occlusion The patients in the manuscript have given written informed con-
under the surgical caps. sent to publication of their case details.

JEADV 2021, 35, 589–596 © 2020 European Academy of Dermatology and Venereology
Occupational Dermatoses from PPE during COVID-19 (Review) 595

Author Contribution 20 Hamann CP, Rodgers PA, Sullivan K. Allergic contact dermatitis in dental
professionals: effective diagnosis and treatment. J Am Dent Assoc 2003;
All the above authors had full contributions to the drafting and
134: 185–194.
preparation of this manuscript and have taken due care to 21 Donovan J, Skotnicki-Grant S. Allergic contact dermatitis from formalde-
ensure its integrity. hyde textile resins in surgical uniforms and nonwoven textile masks. Der-
matitis 2007; 18: 40–44.
22 Singh M, Pawar M, Bothra A, Choudhary N. Overzealous hand hygiene
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