Professional Documents
Culture Documents
November 2020
10. Protein restriction in CKD: 18. The safest diagnostic modality to assess renal size:
a. Increase erythropoietin production a. Ultrasound of the kidney
b. Reduced uremic symptoms b. CT Scan of the kidney
c. Increased renal blood flow c. IVP
d. Reduced renal osteodystrophy d. Magnetic resonance imaging (MRI)
Slow the rate of decline in 19. Which of the following causes a normal anion gap
early stages metabolic acidosis?
Reduce uremic symptoms a. Rhabdomyolysis
b. Diabetic ketoacidosis
11. Which of the following is seen in patients with CKD who c. Lactic acidosis
present with Malnutrition - Inflammation Atherosclerosis d. Renal tubular acidosis
Calcification (MIAC) syndrome?
a. Decrease in C-reactive protein - increased
b. Increase serum albumin - decreased
c. Decrease in fetuin
d. Increase in glucagon
23. Which is NOT a trigger for mesangial matrix expansion 28. What is most likely diagnosis of a 20 y/o male who
in DM glomerulopathy? consulted the OPD for recurrent episodes of gross
a. Increase myoinositol hematuria, with unremarkable PMH and family history.
b. Advanced glycosylated end products BP=110/70, (-) edema, (-) proteinuria, rbc=TNTC?
c. Direct effect of hyperglycemia on mesangial matrix a. IgA Nephropathy
d. Release of growth factors b. TBMD
c. Alport’s syndrome
d. Henoch Schoenlein Purpura
IgA Nephropathy
Normal BP
Gross hematuria
Dysuria
Edema and nephrotic syndrome - less frequent
34. What will differenitate Henoch-Schoenlein purpura 40. Which glomerular disease will NOT have
from IgA Nephropathy who presents with similar immunofluorescence finding on renal biopsy of
glomerular syndrome and histopathologic findings? predominant mesangial IgA deposits?
a. Developed after URTI a. IgA Nephropathy
b. Normal serum IgA level b. DM Nephropathy
c. Glomerular syndrome responsive to steroids c. Henoch-Schoenlein Purpura
d. Clinical findings of arthralgia, abdominal pain and d. Lupus Nephritis
purpura.
41. What is the severity of hyperkalemia in a 60 y/o female,
35. A 20 y/o female was admitted for edema and oliguria. diabetic, with serum potassium=6.8 meq/L and ECG changes
She complained of on and off fever with sorethroat 3 weeks of multifocal PVC’s?
PTA. BP=160/100, with periorbital edema. Urinalysis a. Mild
revealed proteinuria=(+)1, rbc = 20-30hpf. What serological b. Critical
test will give you the most likely diagnosis? c. Moderate
a. ANCA d. Severe
b. Anti GBM titer
c. ASO titer
d. ANA titer
46. Which is NOT true with regards to tubular absorption of 52. What is the type of RTA in a 32 y/o male presenting
water and sodium? with lower extremity weakness with urinalysis: pus cells=
a. Proximal tubule is impermeable to sodium and 8-15 hpf, pH=7.0, serum potassium=2.8 meq/L, ABG:
water pH=7.20, pCO2= 19, HCO3 = 10 and renal UTZ with
b. Descending loop of Henle is impermeable to nephrocalcinosis?
water and permeable to sodium - permeable to a. Type 1
water, impermeable to sodium b. Type 2
c. Collecting ducts is permeable to water with ADH c. Type 3
and permeable to sodium with aldosterone d. Type 4 (??)
d. Ascending loop of Henle is permeable to water and
impermeable to sodium 53. To expand the extracellular compartment what IV fluids
will you use?
47. What diuretic causes metabolic alkalosis and a. 0.9% NaCl (dapat NSS and not D5W)
hypokalemia? b. 5% Dextrose in Water
a. Furosemide c. Albumin
b. Spironolactone d. Dextran
c. Amiloride
d. Hydrochlorthiazide 54. What clinical condition will not dictate urgent
treatment of Hypokalemia? - admission to hospital,
48. What will be the immediate treatment in a 68 y/o with continuous cardiac monitoring, immediate treatment
serum potassium = 6meq/L, and ECG findings of ventricular a. Acute myocardial infarction
tachycardia? b. Hypokalemic patient for emergency surgery
a. D50-50 plus Regular Insulin c. Serum potassium <3meq/L
b. Dialysis d. Hepatic encephalopathy
c. Calcium gluconate e. Presence of cardiac arrhythmia
d. Salbutamol nebulization
55. What body fluids have highest potassium content?
49. What can cause normal anion gap metabolic acidosis? a. Small intestinal fluids
a. ESRD b. Colonic fluids
b. Type 2 RTA - and diarrhea c. Saliva
c. COPD in acute exacerbation d. Gastric fluids
d. Ethylene glycol toxicity
56. What will NOT be included on the differential diagnosis
50. What factor have no effect on the development of signs of a 52 y/o female with laboratory results of serum
and symptoms in 65 y/o hypertensive noted to have serum potassium = 3.0, AG= 10, pH = 7.14, pCO2 = 20, HCO3 = 14?
sodium = 110 meq/L a. Distal RTA
a. Other associated abnormalities in the brain b. Proximal RTA
b. Rate of decline in serum sodium c. CKD stage 5
c. Degree of changes in serum sodium d. Cholera - (+) diarrhea and vomiting
d. The age of the patient
57. What condition will NOT cause both hyponatremia and
51. What clinical findings will differentiate moderate hypernatremia?
volume depletion from severe volume depletion? a. Vomiting and diarrhea
a. Dry mucous membrane - mild b. Primary hyperaldosteronism -hypernatremia only
b. Resting tachycardia c. Mannitol administration
c. Flat neck vein d. Encephalitis
d. Hypotension
58. What etiology of Hypokalemia is NOT due to
Resting tachycardia and Postural hypotension intracellular shift of potassium?
To differentiate moderate from mild a. Metabolic Alkalosis
To differentiate severe from moderate b. Beta blockers
c. Hyperthyroidism
d. Salbutamol
e. Insulin
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November 2020
4. Which serologic marker for R.A maybe seen in 9. Schirmer’s test is performed in patients suspected
affected patients years before the onset of clinically with:
apparent disease and is more specific for the diagnosis a. Sjogrens syndrome - test for tear secretion
of RA? b. Mixed connective tissue disease - Reynaud’s
a. C-reactive protein phenomonen
b. Rheumatoid factor - nonspecific c. SLE
c. Anti-cyclic citrullinated peptide d. Systemic sclerosis
d. ASO titer
10. The most common neuropsychiatric manifestation
5. Bacteria enters the joint space from the blood of SLE:
stream because of: a. Migraine
a. Large blood volume pass through synovial b. Depression
vessels c. Psychosis
b. Absence of limiting basement membrane of d. Cognitive dysfunction
synovial capillaries
c. Heavy microbial load in the blood
d. Poor quality of the cartilage
11. S. 35 yo male athlete, 5’5ft 140lbs consulted 17. Among the connective tissue disease, this has the
because of left ankle arthritis of 1 day. He exercised in highest mortality:
the gym for 6h and claims to have drank Gatorade after a. MCTD
the exercise. Pain score was 10/10 and the joint is b. Sjogrens syndrome
warm, tender, swollen, with limitation of motion. c. Dermatomyositis
WHAT IS YOUR DIAGNOSIS? d. Systemic sclerosis
a. Gout
b. Fracture 18. A connective tissue disease with overlapping
c. Sprain features of Scleroderma, SLE, and polymyositis is
d. Septic arthitis known as:
a. Mixed connective tissue disease
12. M.L 23 yo call center agent, consulted because of 2 b. Undifferentiated CTD
month history of arthritis involving the ankle, MCP, c. Fibromyalgia syndrome
shoulder, and elbows. The arthritis tends to be d. NONE
migratory, symmetric and non erosive. A month later
she noted photosensitivity, fever and cough. Which test 19. What autoantibody test is most specific for active
would you request to strengthen your diagnosis? - SLE, nephritis and vasculitis?
infectious arthritis a. AntiSm
a. ANA b. AntiJo
b. CRP c. AntidsDNA
c. CBC d. ANA
d. Rheumatoid gout
20. The dermatologic lesion seen in patients with
13. The first line treatment of patients with Ankylosing Dermatomyositis include:
spondylitis is: a. Heliotrope rash - upper eyelid
a. NSAIDS b. Mechanics hand
b. Paracetamol c. Gottrons papules - most common
c. Opioid derived drugs d. AOTA
d. Glucocorticoids
21. Most common etiologic agent of bacterial arthitis:
14. What is the characteristic of the monosodium urate a. E.coli - 3rd
crystal under polarized microscopy? - Gout b. Neisseria sp.
a. Rectangular, positively birefringent c. S. Aureus
b. Globular, non birefringent d. Streptococcus pneumoniae - 2nd
c. Needle shaped, negatively birefringent
d. Rhomboid, negatively birefringent 22. Bony hyperthrophy of the distal interphalangeal
joint is known as:
15. Which of the inflammatory myopathies is not a. Bouchards node - Proximal interphalangeal
responsive to glucocorticoids? b. Swan neck deformity
a. Inclusion body myositis c. Heberdens node
b. Polymyositis d. Oslers node
c. Dermatomyositis
d. NONE 23. This rheumatologic condition usually presents as
chronic inflammatory oligoarthitis
16. Hyperextension of the first interphalangeal joint a. Rheumatoid arthitis
with palmar sublaxation of the first b. Septic arthritis
metacarpophalangeal joint will manifest as: - c. Reactive arthritis
Rheumatoid arthritis d. Gouty arthritis
a. Swan neck deformity - felxion of DIP &
hyperextension of PIP joint 24. Which of the following statement is not true
b. Piano key deformity regarding osteoarthritis?
c. Boutonnier deformity - flexion of PIP & a. More common in men than women - female
hyperextension of DIP joint is more common
d. Z-shaped thumb b. Joint subjective to repetitive use are prone to
develop osteoarthritis
c. Common in weight bearing joint
RHEUMATOLOGY SAMPLEX
November 2020
d. Obesity increases the risk 30. The diagnosis of osteoarthritis is most likely in a 60
yo patient with right knee pain if:
25. Finkelstein test will be positive with this a. White cell count of synovial fluid is 700
periarticular disorder: cells/hpf
a. Carpal tunnel syndrome - (+) Tinel’s sign b. Sugar level of synovial fluid is 90mg.ml
b. Iliopsoas bursitis c. Blood uric acid is 320 mg/dl
c. De Quervains tenosynovitis d. Protein content of synovial fluid is 50mg/ml
d. Medial epicondylitis - golfers elbow /
resistance to wrist flexion 31. An inflammatory joint problem is more painful or
symptomatic in what situation?
26. What do you call the condition where one or more a. During activity
fingers of the hand can lock or snap into a bent position, b. After exposure to cold temperature
causing pain and lack of function on attempted c. After rest or sleep
straightening? This involves inflammation of the d. At bedtime
sheaths of the flexor digitorum tendons.
a. Carpal tunnel syndrome 32. The most common site of spinal Tuberculosis in
b. De Quervains tenosynovitis adult: - thoracolumbar spine
c. Lateral epicondylitis a. Sacral vertebra
d. Stenosing tenosynovitis - trigger finger b. Low cervical
c. Lower thoracic and upper lumbar
27. A 36 yo healthy male, sexually active developed d. Upper thoracic
fever, malaise with acute right knee pain, swelling and
decreased range of movement. His synovial fluid gram 33. How long will you give antibiotic therapy in this
stain showed Gram-positive cocci in clusters. Which of particular patient?
the following microorganism is the most probable a. 4 wks
cause? b. 6 wks
a. Escherichia sp c. 1 wk
b. Pseudomonas sp d. 2 wks
c. Streptococcus sp
d. Staphylococcus sp 34. A 36 yo healthy male, sexually active developed
fever, malaise with acute right knee pain, swelling and
28. What do you call this condition when the joint decreased range of movement. His synovial fluid gram
capsule adheres to the humeral neck causing restricted stain showed Gram-positive cocci in clusters. The best
active and passive motions in all planes? empiric therapeutic option for this case is:
a. Frozen shoulder - adhesive capsulitis a. Penicillin
b. Bicipital tendinitis - anterior shoulder pain b. Ceftriaxone
c. Rotator cuff tendinitis - pain in abduction c. Vancomycin
d. Impingement syndrome d. Piperacillin-tazobactam
29. A 46 yo farmer, diabetic complained of a wound 35. Which statement is true of pseudogout?
over his hand. This started as a small, red, painless a. More common in female - males = females
nodule that progressed into an ulcerated lesion that b. Commonly affects the metatarsophalangeal
spreads in a line following the draining lymphatic joint - affects knee, hand, polyarthricular
channels forming nodules on the skin along the way. He c. Maybe precipitated by severe illness, trauma
later complained of left ankle joint pains and swelling or surgery
with skin abscess. What is the most probable fungal d. ALL
infection implicated in this patient?
a. Cryptococcosis 36. A patient with arthritis of the knee commonly
b. Blastomycosis assumes the position of:
c. Histoplasmosis a. External rotation
d. Sporothricosis b. Extension
c. Abduction
d. Flexion
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November 2020
37. A patient was diagnosed with De-Quervains 43. Which of the following drugs oxidize uric acid to
tenosynovitis what maneuver will you do to test if the allantoin?
patient is positive for the said condition? a. Febuxostat - allopurinol / xanthin oxidase
a. Drop arm test - rotator cuff tendinitis inhibitor
b. Phalen’s test - carpal tunnel syndrome b. Probenecid - uricosuric drugs
c. Finkelstein’s test c. Anakinra
d. Tinel’s test - carpal tunnel syndrome d. Pegloticase
38. A.L, 40 yo female vendor consulted because of left 44. What do you call the bony enlargement found on
knee arthritis of 7 days. No history of trauma, but a the distal interphalangeal (DIP) joint in patients with
history of fever and cough was present. PE (+) bulge osteoarthitis?
sign, warm, tender, with limitation of movement was a. Bouchard’s node - PIP
noted. What is the best diagnostic test for her b. Osteophytes
condition? c. Heberden’s node
a. Xray of both knees d. Tophi - gout
b. Blood uric acid determination
c. Synovial fluid analysis 45. An 80 y/o grandmother complained of painful
d. Chest xray knees more pronounced on walking. On physical
examination she was noted to have bilateral genu
39. The features of fibromyalgia include diffuse varum, (+) crepitations both knee joints, (+) non-tender
tenderness at discrete anatomical sites and: bony nodules on the proximal and distal
a. Polyarthritis interphalangeal joints of the 2nd and 3rd digits. If this is a
b. Sleep disturbance case of Osteoarthritis, the pathologic sine qua non of
c. Chest pain this condition is
d. Fever a. Outgrowth of osteophytes
b. Sclerosis of subchondral bony plate
40. An acute attack of gout needs to be distinguished c. Weakness of muscles bridging the joint
from: d. Hyaline articular cartilage loss and articular
a. Pseudogout cartilage loss
b. Cellulitis
c. Septic arthitis 46. This is one of the commonly affected joints in this
d. ALL condition
a. Ankle joint
41. A complete deficiency of the enzyme b. Wrist joint spared in OA
hypoxanthine-guanine phosphoribosyl transferase c. Elbow joint
(HGPRT) where patients present with severe neurologic d. 1st metatarsal phalangeal joint
findings, mental retardation developing gout or renal
stones because of the persistent hyperuricemia is called 47. ____provides the cartilage its tensile strength
a. Glycogen storage disease type III a. Hyaluronic acid
b. Kelley seegmiller b. Matrix metalloproteinase
c. Lesch-Nyhan syndrome c. Type 2 collagen
d. Glycogen storage disease type 1 d. Aggrecan - provides compressive stiffness
Articular characterized by
A. crepitus, deformities, swollen 18. Destruction of cartilage in septic arthritis occur
B. pain with activity within _ hrs
C. point tenderness A. 24 hours
D. pain at passive and active motion B. 48 hours
C. 72 hours
7. Consider as most common type of arthritis: D. 96 hours
A. Gouty Arthritis
B. Osteoarthritis 20. Infectious arthritis due to S. aureus are treated with
C. Rheumatoid Arthritis oxacillin, nafcillin, and vancomycin are treated for
D. Infectious Arthritis A. 1 week
B. 2 weeks
8. Joint protectors EXCEPT: C. 3 weeks
A. Afferent Sensory D. 4 weeks
B. Joint Capsule
C. Synovial Fluid 22. Rheumatoid Arthritis
D. Bursa A. Acute Polyarticular
B. Chronic Polyarticular
10. Pain in osteoarthritis arises from the following except C. Acute Monoarticular
(sorry, can't remember yung order ng choices) D. Chronic Monoarticular
A. Capsular Stretching
B. Cartilage Loss 23. A patient complaining of reactive symmetric form of
C. Synovitis polyarthritis with visceral or disseminated tuberculosis is
D. Bone Marrow Erosion/Effusion diagnosed with what disease?
A. Poncet’s disease
B. Reiter’s syndrome
12. Initial analgesic of choice in patients with OA of C. TB arthritis
knees, hip and ankle joints D. Charcot disease
A. NSAID
B. Prednisone 24. Reactive arthritis is common in young male, it is
C. Acetaminophen linked to what potential genetic predisposing factor?
D. Opiate HLA-B27
d. Heart Transplant
1. A patient was admitted with BP of 220/120 mmHg with e. Eplerinone
left side weakness fundoscopy revealed Papilledema. He is
in what stage of hypertension 6. The Gold standard in the diagnosis of heart failure is
a. Hypertensive Emergency which of the following.
b. Hypertension Stage 1 - 140/90 - 150/99 a. NT PRO BNP
c. Hypertensive Urgency b. ECG
d. Hypertension Stage 2 - >160/100 or more c. 2D echo with doppler
d. Nuclear imaging
2. 12 lead ECG findings of ST elevation in Lead I, AVL, V5-V6
a. Lateral Wall 7. 50 male patient is in chronic heart failure and had been
b. Infero Lateral Wall taking Digitalis and Aldactone with out improvement from
c. Diffuse or extensive anterior wall his easy fatigue and shortness of breath. BP=100/60 HR=70.
d. Antero Lateral Wall 2D echo revealed Eccentric left ventricular hypertrophy with
e. Inferior wall ejection fraction = 25%. What will be the best drug for this
patient.
a. Trimetazidine - inc. oxygenation
b. Nebivolol - inc vasoldilator
c. Furosemide - for dyspnea
d. Ramipril - ACE inhibitor
e. Sacubitril/Valsartan - ARB
25. A 32 y/o asymptomatic female has rapidly rising, 32. A 15 y/o female patient develops pleuritic chest pain,
forceful pulse that collapses quickly and with a BP 140/40. fever, and a friction rub heard at the lower sternal border.
The most likely diagnosis is The most likely involved portion of the heart
a. Aortic stenosis a. Myocardium
b. Mitral stenosis b. Pericardium
c. Mitral regurgitation c. Valves
d. Aortic regurgitation d. Myocardium
33. Which of the following symptoms of aortic stenosis has
26. Which of the following condition produces a continuous the poorest prognosis?
murmur? a. Syncope
a. Mitral stenosis b. Dyspnea
b. Aortic stenosis with aortic regurgitation c. Congestive heart failure
c. Tricuspid regurgitation d. Angina pectoris
d. Patent ductus arteriosus
34. Differential diagnosis of Mitral stenosis: Increase in the
27. Differential diagnosis of Mitral stenosis: Diastolic intensity of murmur on inspiration
murmur… a. Mitral stenosis
a. Mitral stenosis b. Tricuspid stenosis
b. Aortic regurgitation c. Both
c. Both d. Neither
d. Neither
Diastolic murmur: Aortic regurgitation, Pulmonic 35. 62 y/o female hypertensive and diabetic complained of
regurgitation, Tricuspid stenosis, Mitral stenosis right buttocks pain while walking for more than 200 meter
and is relieved by rest. If this is a case of peripheral arterial
disease, predict the location of the arterial stenosis.
a. Distal abdominal aorta
b. Right iliac artery
28. A patient with Valvular heart disease with less than c. Right dorsalis pedis artery
ordinary activity causes symptoms is classified based on d. Right anterior tibial artery
New York Heart Functional Classification e. Right femoral arterya
a. Class I
b. Class II 36. Which of the following is NOT a major Jones criteria?
c. Class III a. Subcutaneous nodules
d. Class IV b. Arthralgia
c. Chorea
29. Graham Steele murmur is a high pitched, decresendo d. Carditis
diastolic murmur heard along the left sternal border is e. Ertythema marginatum
associated with
a. Tricuspid regurgitation 37. A symptomatic 29 y/ female with a murmur is found to
b. Pulmonic regurgitation have mitral stenosis on echo. Which of the following
c. Aortic stenosis statement is TRUE of mitral stenosis?
d. Aortic regurgitation a. The murmur radiates to carotids
b. S3 may be present
30. A patient with mitral stenosis was noted to have a c. High pitch systolic murmur
heart rate of 120 bpm, BP = 100/60. Which of the following d. Associated with loud S1
agent has a negative chronotrophic effect with positive
inotrophic effect? 38. Which of the following treatment with degenerative
a. Digitalis calcific aortic stenosis slows progression of leaflet
b. ACE inhibitors calcification.
c. Non dihydropyridine calcium channel blockers
a. Beta blockers
d. Beta blockers b. Digitalis
c. ACE inhibitors
31. The click and murmur in a patient with MVP occurs
d. HMG-CoA reductase inhibitors
earlier with
a. Standing 39. Differential diagnosis of Mitral Stenosis: Left ventricular
b. Handgrip enlargement is present
c. Isometric exercise
a. Mitral stenosis
d. Squatting b. Mitral regurgitation
CARDIOLOGY SAMPLEX
November 2020
44. 50 y/o male underwent partial hip replacement due to 49. Atrial Fibrillation
a left femoral neck fracture 2 to a fall. He is bedridden for
the past 5 days. On the 4th post op day the resident on duty
noticed that the left thigh is markedly bigger than the right
with associated erythema and pain. There is no fever. PMH:
(-) HTN (-) DM2. Family History: (-) CVA, HTN. PSH:
unremarkable. PPE. BP=130/70 HR=90/min RR=20 WT=90 kg.
(-) pallor, APex beat 5th ICSLMCL, (-) heave (-) thrill, regular
rate and rhythm, (-) murmurs. Left thigh 68cm diameter,
No P wave
right thigh 63cm. Left thigh is hyperemic, tender to touch.
Irregular
The diagnostic test to confirmed the diagnosis of acute deep
Slow
vein thrombosis. How will you treat this patient?
CARDIOLOGY SAMPLEX
November 2020
Atrial Flutter
50. Sinus rhythm with PVC 54. Acute rheumatic fever is commonly seen in this age
Wide QRS group?
No preceeding P wave a. 1-12 mo
T wave opposite QRS b. 25-40 yo
Compensatory pause c. 5-14 yo
d. 1-5 yo
Sinus rhythm with PAC 56. Which of the following is a sign of Acute Rheumatic
P wave different fever?
configuration from sinus a. Nausea
beat b. Joint tenderness
Long PR interval c. Malar rash
QRS narrow d. Change in vision
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November 2020
57. Which of the major Jones criteria has the longest latent d. Arthritis, arthralgia elevated ESR
period?
a. Chorea - 3 months 66. The following are complications of acute rheumatic
b. Erythema marginatum fever EXCEPT
c. Arthritis a. Inflammation of heart muscle
d. Subcutaneous nodules - 2-3 wks b. Valve regurgitation
c. Inflammation of the conducting system
58. Most common clinical feature of ARF is d. Pulmonary hemorrhage
a. Chorea - <2 -30%
b. Subcutaneous nodules - 5% 67. Which of the following confirms the diagnosis of ARF
c. Polyarthritis - 60-75% a. CRP
d. Erythema marginatum - <5% b. ASO
c. ECG
59. Which of the following cardiac valves is commonly d. ESR
affected in acute rheumatic fever?
a. Pulmonic 68. A minor jones criteria for the diagnosis of ARF?
b. Tricuspid a. Erythema marginatum
c. Aortic b. Subcutaneous nodules
d. Mitral c. Carditis
d. Migratory arthralgia
60. The hallmark of rheumatic carditis is
a. Pericarditis 69. True regarding subcutaneous nodules:
b. Myocarditis a. Mobile lumps beneath the skin
c. 1st degree AV block b. Associated with chorea - carditis
d. Valvular damage c. Are tender - painless
d. Symmetrical - asymmetrical
61. Rheumatic heart disease is best diagnosed by
a. Auscultation 70. The development of cardiac involvement in patients
b. Echocardiography with recurrent throat infection due to streptococcus can be
c. ECG explained by which mechanism?
d. CXR a. Hypersensitivity reaction to viral products
b. Molecular mimicry
62. The most common form of joint involvement in acute c. Direct damage on the heart tissues by the
rheumatic fever is arthritis. The following described the organism
arthritis in Acute Rheumatic fever except d. Loss of tolerance to self antigen
a. Involves the large joint
b. Polyarthritis 71. 42 yo male diabetic hypertensive with sever progressive
c. Symmetrical chest pain lasting for more than 20 minutes ECG revealed.
d. Migratory ST elevation in V1-V4 with Trop-T (+) quantitative of
480ng/ml. What is your diagnosis?
63. The drug of choice for the treatment of arthritis in acute a. Unstable Angina Pectoris
rheumatic fever is b. NonSTEMI
a. Tramadol c. STEMI
b. Naproxen d. Chronic stable angina pectoris
c. Glucocorticoids e. TIETZE syndrome
d. Aspirin
72. 32 yo male smoker w family history of suddent cardiac
64. The following results would indicate inflammation in a death (father at age 42) complaining of chest pain upon
patient with acute rheumatic fever except: climbing the stairs of the LRT. The discomfort is relieve upon
a. Elevated erythrocyte sedimentation rate resting. ECG revealed to be normal. What is your diagnosis?
b. Decreased hemoglobin & hematocrit a. TIETZE Syndrome
c. Elevated C reactive protein b. Chronic stable angina pectoris
d. Elevated WBC count c. Unstable Angina Pectoris
d. Non STEMI
65. According to the Jones criteria, which of the symptoms e. STEMI
and laboratory result would indicate a diagnosis of ARF
a. Fever, carditis, elevated WBC 73. Sudden chest pain and pallor after coming out of the
b. Arthritis, chorea, positive ASO titer bathroom. She is obese, hypertensive and diabetic.
c. Elevated CRP, ESR, carditis a. TIETZE
CARDIOLOGY SAMPLEX
November 2020
b. NONSTEMI
c. STEMI
d. Chronic Angina pectoris
e. Unstable Angina Pectoris
16. Which of the following is correct in acute retroviral 24. This technique that is done when examining rabid
syndrome? patients can detect the virus in fresh samples of saliva,
a) Not communicable skin, CSF and brain tissues. At the same time, it can
b) Manifest in all HIV patients distinguish the varied rabies virus variants:
c) Influenza or infectious mononucleosis like illness a) Direct fluorescent antibody testing
d) Usually 2 to 4 months after infection b) Rabies virus specific antibodies
c) PCR
17. Which of the following statements is correct about d) RT PCR amplification
rose spot?
a) Salmon colored 25. A 32 year old male presents with chills, fever, and
b) Exclusively in S.typhi anorexia. Examination shows an enlarged spleen. For a
c) Often in the extremities definitive diagnosis of this condition, what must be
d) Appear on the 3rd week of illness seen in the stained peripheral smear?
a) Antibodies to the parasite
18. Standard antiretroviral drug for treatment of naive b) Gametes
patients consist of? c) Asexual forms of the parasite
a) Single INSTI d) Sexual forms of the parasite
b) Dual PI
c) Triple ARV, 1 from any of the ARV group 26. A 54 y/o street sweeper is bitten by a stray dog in the
d) Dual NRTI plus 1 from other group of ARV thighs and abdomen. She presents to the ER with fever,
malaise, anorexia and vomiting. She also feels
19. Confirmatory test for COVID19 paresthesia at the wound site. What phase of the
a) Isolation test clinical stage of rabies is this?
b) Antigen test a) Prodrome
c) Serologic test b) Incubation period
d) NAAT c) Encephalitis
d) Paralytic
20. Person with close contact with a patient suffering from
covid19 should be quarantine within the duration of 27. In cases of malaria acquired through blood transfusion,
the incubation period which is up to? this is absent thus explaining the short incubation
a) 28 days period:
b) 7 days a) Pre-erythrocytic phase
c) 14 days b) Asexual stage
d) 21 days c) Erythrocytic phase
d) Sexual stage
21. What is the usual CSF examination result of a patient
who was bitten at the facial area by a rabid dog? 28. This eye finding is pathognomonic of military
a) Mild mononuclear cell pleocytosis tuberculosis in 30% of cases
b) Bloody non traumatic aspirate a) Choroidal tubercles
c) Normal CSF b) Corneal caseation
d) Normal protein level c) Lenticular ulcerations
d) Vitreal tubercles
22. Malaria during pregnancy caries a significant risk of
morbidy and mortality. Levels of parasitemia are 29. A 38 yo female patient residing near the Sierra Madre
highest and failure to clear the parasites after mountain range was often brought to the hospital as a
treatment is most frequent among primigravids. What child because of bouts of fever and chills. Her fever
medicines are safe to give to pregnant patients with pattern was described as quartan. She is now
malaria for all trimesters? diagnosed with nephrotic sydnrome which is this
a) Mefloquine and artemether specie of Plasmodium. What is the histopathologic
b) Mefloquine and quine appearance of this renal condition?
c) Quinine a) Dense deposits in the endothelium
d) Chloroquine and mefloquine b) Glomerulosclerosis of the subendothelial layer
c) Segmental glomerulonephritis with the splitting
23. What factors are associated with a poor prognosis in of the capillary basement membrane
tetanus? d) Diffuse glomerulonephritis with splitting of the
a) Diastolic blood pressure more than 90mmHg capillary basement membrane
b) Systolic blood pressure less than 140mmHg 30. Hypoglycemia is an important and common
c) Incubation period more than 7 days complication of malaria. This is due to several
d) Incubation period less than 7 days mechanisms cause by the parasite. However,
COMMUNICABLE DISEASES SAMPLEX
November 2020
hypoglycemia can be an adverse effect of this drug d) Non-specific immune response and vascular
which is used widely for uncomplicated and severe endothelium response
falciparum malaria: 37. A 35 y/o male teacher is assigned to train his fellow
a) Lumefantrine teachers living in Turkey. You must prescribe him with
b) Quinine a prophylactic medicine to protect him against malaria
c) Mefloquine while he is in that country for one month. He informs
d) Chloroquine you that he is allergic to doxycycline. What medicine
can you prescribe aside from doxycycline?
31. A 65 year old male matient, exposed to his wife who a) Chloroquine
was diagnosed to have PTB comes to your clinic b) Fansidar
because of low grade fever and cough. DSSM shows c) Lumefantrine
M.tuberculosis bacteria. He reports that he has not d) Primaquine
taken any anti TB drugs. What drug regimen should 38. A 56 yo male farmer develops tetanic spasms and is
you give to this patient? brought to the ER. What is the best drug to control
a) 2 months HRZE/4 months HR these spasms?
b) 56 days streptomycin and ethambutol a) Cetirizine
c) 2 months HRZE/10 months HR b) Diphenhydramine
d) 3 months HRZE/ 4 months HR c) Chlorpromazine
d) Potassium infusion
32. The two forms of rabies that eventually may 39. The two genera in the Rhabdoviridae family contain
deteriorate to moratlity are: species that cause disease to humans. This is the virus
a) Paralytic and comatose that affects a broad range of animals and can cause
b) Spinal and paralytic serious neurologic sequelae when transmitted to
c) Encephalitic and spinal humans:
d) Encephalitic and paralytic a) Vesiculovirus
b) Lapsavirus
33. Aside from a DSSM, this examination may also be c) Vermicolor virus
requested by a physician to definitely diagnose a d) Lyssavirus
patient with tuberculosis:
a) CT scan with contrast 40. True statement regarding Mild Leptospirosis:
b) Nucleic acid amplification test Conjunctival suffusion is a pathognomonic feature
c) Chest xray
d) CT scan with contast 41. Which sexually transmitted agent causes tropical
spastic paresis and T-cell Leukemia?
34. Liver and spleen enlargement, ascites, and wasting are a) HTLV-1
characteristically seen in this type of schistosoma?
a) S. Mekongi 42. A 22 y/o male college student sought consult at the ER
b) S. Hematobium due to a low grade fever for 5 days accompanied by
c) S. Mansoni body malaise, headache and joint pains. He admitted
d) S. Intercalatum to have had unprotected sex witha commercial sex
worker 1 week prior this consultation. Upon
35. Cardiovascular instability in severe tetanus is difficult examination, the medical intern noted blisters which
to manage. Rapid fluctuations in BP and HR may were itchy and painful on the lateral aspect of his penis
happen. This drug has been helpful in improving with clear urethral discharge and tender inguinal
cardiovascular stability by increasing sedation: lymphadenopathy
a) Magnesium sulfate IV a) We should increase the efficiency of transmission
b) Calcium IV infusion by promoting use of contraceptives
c) Captopril
d) Metoprolol 43. Laboratory finding on patient with typhoid fever
except:
36. What are the two host responses that develop in a) Elevated liver enzymes
patients with tuberculosis about 2-4 weeks after b) Leukopenia and neutropenia
infection? c) Positive stool cultures on the 1st week of illness
a) B cell mediated response and tissue damaging d) Bon marrow culture with >80% sensitivity
response
b) Lymphocyte activating response and tissue
damaging response
c) Macrophage activating response and tissue
damaging response
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44. Which is not true regarding Post Diarrhea 1. Kissing disease is best described by which of the
Complications? following?
a) Campylobacter infection = Guillain - Barre a. Fever, pharyngitis, chylosis for 1-4 weeks
Syndrome b. Fever, pharyngitis, lymphadenopathy for
b) Giardia = Hemolytic Uremic Syndrome 1-4 weeks
c) Chronic diarrhea = lactase deficiency c. Fever, pharyngitis, hepatomegaly lasting for
d) Salmonella = reactive arthritis 1 to 4 weeks
d. Fever, pharyngitis, splenomegaly lasting for
45. True statement regarding the prognosis of a patient 1 to 4 weeks
who had leptospirosis?
a) Majority of patients recover 2. Which of the following is correct in the
management of infectious diarrhea?
46. True statement regarding Schistosomiasis in the a. Mainstay treatment is adequate antibiotic
Philippines b. Empirical antibiotic for dysentery
a) Transverse myelitis is the second most c. Empirical antibiotic for patients with fever
problematic CNS problem d. Antimicrobial is a must if
enterohemorrhagic E.Coli is suspected
47. Which histopathologic finding is correctly matched
with a patient’s sign/symptom? 3. Regarding HIV infection the population that is least
a) Swelling with vacuolation= calf pain likely affected is:
a. Male having sex w/ male (MSM)
48. A 36 y/o MSM presented at the ER with fever, b. Commercial sex workers & client
generalized rashes not sparing the soles and palms c. Healthcare workers (HCW)
a) Aciclovir d. People who inject drugs (PWID)
49. True statement regarding praziquantel: 4. Infectious diarrhea associated with contaminated
a) The only available antiparasitic drug for egg is due to:
schistosomiasis a. E.coli
b. Shigella
50. Which is not true regarding the virulence factors c. Salmonella
utilized by microbes causing diarrhea? d. Vibrio cholerae
a) Neurotoxins may cause vomiting in patients after
ingestion of contaminated food 5. You have an emergency travel to a known P.
Falciparum malaria endemic area within 2 days.
51. Which of the following antibiotic has the correct dose Which of the following is your best choice of
for treating Salmonella prophylactic antimalarial drug?
a) Chloramphenicol 25mg/kg TID a. Primaquine - prevents drug resistant
falciparum and vivax malaria in adults
52. Which is not true in Proctitis b. Doxycycline
a) Presents as chronic diarrhea c. Mefloquine - for pregnant women WHO
53. Laboratory findings compatible with Leprospirosis (2nd and 3rd tri) for CDC (1st tri)
except: d. Choloroquine -can be used for prophylaxis
a) Leukocytosis with right shift and treatment
54. True statement regarding Traveler’s diarrhea 6. Which of the following is correct in transfusion
a) Enterotoxigenic E.coli is the single most common malaria?
important cause a. Primaquine is highly recommended
b. Clinical features is different from mosquito
55. A 22 y/o male college student sought consult at the ER borne
due to a low grade fever for 5 days accompanied by c. Longer incubation period
body malaise, headache and joint pains. He admitted d. None
to have had unprotected sex witha commercial sex
worker 1 week prior this consultation. Upon 7. A 22 y/o female came in due to dysuria and
examination, the medical intern noted blisters which frequency for 2 days. Urinalysis showed pyuria with
were itchy and painful on the lateral aspect of his penis bacteria of less than 100 cfu/ml. What is your initial
with clear urethral discharge and tender inguinal impression?
lymphadenopathy a. Acute urethral syndrome
a) Chancroid caused by H.ducreyi would cause a
painful genital lesion.
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b. Bacterial cystitis - w/ single patho (e.coli 14. This is the reason for the high concentration of the
and staph sapro) at counts of >1000 / ml of rabies virus in the saliva of an infected animal.
urine a. Viral reproduction happens in the salivary
glands
8. Diarrhea after eating raw sea foods is caused by b. Saliva constrains a lot of co-inhabiting
which of the ff EXCEPT? bacteria and viruses.
a. Vibrio specie c. Saliva is alkaline making the milieu more
b. Salmonella conducive to viral reproduction
c. Giardia lamblia d. Viral shedding from the sensory nerve
d. Hepatitis A endings in the oral mucosa
9. Which is not part of the management of typhoid 15. A 40 y/o patient from Kenya has a hx dysuria and
fever? hematuria. Circulating cathodic antigen is positive
a. Steroid therapy for complicated cases. in the urine. Lately he was complaining of nocturia,
b. Admit px with suspected salmonellosis dribbling and incontinence. The above case is
c. Surgery in chronic carries with anatomical caused by.
abnormalities (biliary stones) a. S. Mansoni
d. Chronic carrier may be managed with an b. S. Mekongi
appropriate antibiotic c. S. Japonicum
d. S. Haematobium
10. Infectious diarrhea associated with contaminated 16. A 40 y/o male farmer has bouts of melena and
egg is due to hematemesis. Ultrasound reveal periportal or
a. E. coli symmers clay pipestem fibrosis. Which of the
b. Shigella following is correct?
c. Salmonella a. His condition is more common in
d. Vibrio cholera adolescents
b. Due to egg-induced granulomatous
11. A 21 y/o male from Manila came to the ER due to responses -s.mansoni and japonicum
frequency loose bowel movements (5 episodes few c. Liver function is usually severely affected
hours prior to consult-mucoid, often blood d. Due to early inflammatory hepatosplenic
streaked). When asked by a medical clerk regarding schistosomiasis
his travel history, he said he attended a family
reunion in Cavite 2 days ago. Where they had some 17. A 22 y/o female patient came at the ER due to
crustaceans, fresh vegetable salad and fried rice. severe right upper quadrant abdominal pain.
His stool exam showed polymorphonuclear History revealed she had been febrile for 3 days
leukocytes. Which of the following could be most and had noted a moderate amount of vaginal
likely etiologic agent discharge for a week now. An impression of pelvic
a. Vibrio parahaemolyticus inflammatory disease was made by the IM resident.
b. Bacillus cereus - fried rice What would be your expected findings that would
c. Clostridium perfringens contribute to the diagnosis?
d. Staphylococcus aureus a. Whitish curd-like cervical discharge
b. Elevated SGPT, SGOT, Elevated WBC & ESR
12. Organism responsible for diarrhea associated with c. Negative pregnancy test, (+) fluid filled
abdominal cramps without fever caused by heat tubes seen via a transviganal utz
resistant spores in inadequately cooked gravy. d. Presence of “external dysuria” -acute
a. Enterotoxigenic E.coli urethral cys
b. Clostridium difficile
c. Bacillus cereus 18. A 25 y/o seafarer consulted the OPD with his
d. Campylobacter jejuni complaint of Urethral discharge which has been
going on for 8 days. He has no fever but complains
13. Hemolytic uremic syndrome in patient with of nontender lymphadenopathy in his bilateral
diarrhea is associated with inguinal areas and 1 cm ulcer with clean base at the
a. Hepatitis a inferior aspect of his penile shaft. What will you
b. EPEC E. coli request to confirm the diagnosis?
c. STEC E.coli a. Gram stain -LGV
d. Low mortality b. COPT-circumoval prescription test (schisto)
c. Tzanck smear herpes
d. Dark field microscopy syphilis
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24. Which of the following is most likely an acute 30. True statement regarding Swimmer’s itch:
retroviral syndrome after two weeks of high risk a. Serum sickness-like illness brought about
exposure by commencement of oviposition by
a. Acute viral hepatitis like illness sexually maturing schistosomes
b. Acute meningococcemia like illness b. Rash may disappear quickly in patients
c. Acute influenza like illness exposed for the first time
d. None c. Major pathologic lesions are large
granulomas and fibrosis
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d. Commonly acquired 2-12 weeks after b. Ultrasound may show distended bladder
exposure with S.hematobium hydroureter or hydronephrosis
c. Urinary egg is abundant
31. True complication of Salmonellosis except: d. Cytoscopy may reveal sandy patches
a. Reversible psychosis
b. Neuropsychiatric symptoms 38. TRUE statement on management of Infectious
c. Hepatitis diarrhea:
d. Relapse with a different strain type a. ORS formulations containing rice or cereal
may not be as effective as glucose-based
32. The leading cause of mortality in advance HIV solutions
disease is b. IV fluid infusion is usually needed
a. Tuberculosis c. The current WHO recommendation states
b. Cryptococcal meningitis that 2.6gm NaCl is better than 3.5gm NaCl
c. Pneumocystis pneumonia as component of Oral rehydration
d. Severe bacterial infection solutions - dec. osmolarity; low stool
output, vomiting
33. TRUE statement on diagnostic methods for d. IV antibiotics is preferred over oral
Leptospirosis:
a. Blood culture has high specificity and 39. A 40 year old patient from Kenya has a history of
sensitivity dysuria and hematuria. Circulating cathodic antigen
b. Specimen for MAT is best collected is positive in the urine. Lately he was complaining
during >1week of illness of nocturia, dribbling and incontinence. Drug of
c. A 2 fold rise in the MAT titer is confirmatory choice for this patient is
of the diagnosis - 4 fold a. Praziquantel
d. MAT is the gold standard of diagnosis b. Diethylcarbamazine
c. Albendazole
61. What type of keratoacanthoma is associated with 68. What is the most common type of Basal Cell
immunosuppresion? Cancer?
a. Ferguson-Smith type - family hx (+) crater form a. Pigmented BCC
scar b. Nodular BCC
b. KA dyskeratoticum et segregans c. Superficial BCC
c. Eruptive type d. Rodent ulcer
d. KA centrifugum marginatum- peripheral
expansion 69. Which of the following nevi presents as a pinkish
slightly scaly papule?
62. What lesion is seen in the sign of Leser Trelat? a. Spitz nevus
a. Seborrheic keratoses b. Balloon cell nevus
b. Actinic keratoses c. Intradermal nevus
c. Dermatofibroma d. Halo nevus
d. Solar lentigenes
71. A 65 yo female consulted because of a nonhealing 78. Which of the following are expected findings in
eczematoid patch on the right areola accompanied by perioral dermatitis?
retraction of the nipple. What is your diagnosis? a. Comedones
a. Erythroplasia of Queyrat - penis b. Vesicles
b. Nipple eczema - (-) nipple retraction c. Pustules
c. Bowen’s disease - erythrophagia d. Telangiectasia
d. Paget’s disease
84. A 26 yo female presented with multiple 91. Which of the following is pathognomonic of
wrythematous oval papules with collarette scaling dermatomyositis?
oriented in a Christmas tree pattern at the back. Which a. Procimal muscle weakness
of the following statements is TRUE about this b. Gottron’s papules
condition? c. Shawl sign
a. It heals spontaneously in 2 wks - 6 to 12 weeks d. Aota
b. Pruritus may or may not be present
c. Oral steroids should be avoided 92. Fungal abscess is known as
d. Sun exposure will worsen the lesions a. Kerion
b. Furuncle
85. Aside from fluorinated toothpaste, what is a c. Carbuncle
common cause of perioral dermatitis? d. Maliariapustulosa
a. Topical steroids
b. Lipstick 93. Enanthem in rubella presenting as minute red
c. Mouthwash macules on the soft plate and uvula in some patients as
d. Cosmetics the prodrome resolves before the exanthema appears
is known as
86. What is the implication of an early onset of a. Scotoma
psoriasis? b. Forscheimer spots - rubella
a. It will resolve by the age of puberty c. Bitot’s spot
b. It tends to involve other organs d. Koplik’s spot - rubeola/measles
c. It may be associated with an autoimmune
disorder 94. Which of the following is the principal cell of
d. It will have a less stable course epidermis?
87. Heliotrope is characterized by which of the a. Mast cells
following? - telangiectasia b. Melanocytes
a. Dilated capillaries c. Langerhan’s cells
b. Violaceous discoloration in the periorbital d. Keratinocytes
areas
c. Thickening of the skin on the face 95. Which of the following organisms cause tinea
d. Erythematous to violaceous papules and a. Epidermophyton flucossum - tinea pedis
plaques found on the metacarpophalangeal b. Aspergillus fumigatus
joints c. Histoplasma capsulatum
d. Candida albicans
88. Non medical management of Tinea unguium:
a. Amorolfine 96. Because complications of varicella are more severe
b. Nail avulsion in adolescnets and adults, which of the followin drugs is
c. Itraconazole recommended?
d. Terbinafine a. Tenofovir
b. Retrovir
89. Which of the following is true of herpes zoster? c. Famvir
a. Arthritis may develop in adults - arthritis d. Acyclovir
b. Lesions are polymorphic - varicella
c. Vesicles are uniform in size - clusters 97. Which of the following drugs are included in the
d. Lesions are flesh colored umbilicated papules - WHO MB regimen for the management og
molluscum contagiosum multibacillary leprosy?
a. Pyrazinamide
90. Which of the following are true of molluscum b. Thalidomide - erythema nodosum leprosum
contagiosum? (Jopling type 2)
a. Umbilicated vesicles are frequently grouped c. Clarithromycin
b. Mosaic pattern is seen in clusters of several d. Clofazimine - rifampicin & dapsone
vesicles
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b. Physiologic reserve
1. Tumor marker for testicular cancer c. Gender
a. PSA - prostate cancer d. Age
b. CA 15-3 - breast cancer
c. AFP 7. Vinorelbine targets what phase of the cell cycle
d. CEA - colorectal cancer a. S
b. M
2. A 65 yo female presents with odynophagia and c. G1
weight loss. Endoscopy revealed an esophageal mass d. G2
and biopsy of the mass revealed adenocarcinoma. On
complete work up, patient was found to be stage II 8. The histopath/cytology revealed: Squamous cell
esophageal cancer but because of his co-morbids; carcinoma of the lung. Base on the CT scan results, the
uncontrolled hypertension & diabetes mellitus type II patient is a stage IV squamous cell carcinoma of the
and post myocardial infarction was found to be lung. If you are planning to give chemotherapy, which is
medically inoperable but is still ECOG 1. What would be the best protocol to give?
the standard next line of treatment for this patient? a. Docetaxel + Cisplatin
a. ChemoRT - combination chemotherapy & b. Paclitaxel + Cisplatin
radiation therapy as the initial tx c. Paclitaxel + Carboplatin
b. Radiation therapy - spares perioperative d. Gemcitabine + Cisplatin
morbidity
c. Chemotherapy 9. Most common side effect of bevacizumab seen in
d. Best supportive care clinical practice today
a. Arterial thromboembolism
Stage I & II - Surgery and then ChemoRT b. Hypertension
Stage III & IV - ChemoRT only c. Bowel perforation
d. Hemorrhage
3. Cancers possibly cured with high dose chemotherapy 10. In high risk settings, can be used prophylactically to
with stem cell support prevent the development of leptomeningeal disease
a. Choriocarcinoma and brain metastasis in acute leukemia and lung cancer
b. Multiple Myeloma a. Radiation therapy
c. Colon Carcinoma b. Surgery
d. Renal cell Carcinoma c. Biologic therapy
d. Chemotherapy
Cancers possibly cured with high dose
chemotherapy with stem cell support: 11. A physically fit PS 0, 61 year old male is seen by a
Breast cancer thoracic surgeon for a newly diagnosed
Gestational Trophoblastic neoplasia adenocarcinoma of the lung. Patient was found to be
Testicular cancer Stage II Non small cell lung cancer upon completion of
work up. Patient underwent Left upper lobectomy.
Patient comes to see you post-operatively. The next
step should be:
4. Mechanism of action of Bevacizumab a. Give adjuvant chemotherapy alone for 6 cycles
a. Inhibition of VEGF b. Give oral TKI for 6 cycles to avoid recurrence
b. Inhibition of bFGF c. Give adjuvant chemo-rt for 3months
c. Inhibition of EGFR - Erlotinib d. Observe and monitor every 3 months for 3
d. Inhibition of PLGF years.
Stage 1 & 2 NSCLC - Surgery + Adjuvant
5. Dose limiting toxicity of Oxaliplatin
chemotherapy
a. Myelosuppression
Stage 3 NSCLC - Chemotherapy +
b. Sensory neuropathy
Radiotherapy
c. Hemorrhagic cystitis
Stage 4 NSCLC - Cornerstone of
d. Emesis
management: Standard medical
management, pain medicatipns &
6. Major determinant of treatment outcome
chemotherapy for palliation
a. Co morbidities
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26. A 59 yo male presents with severe back pain & 32. A 59 yo male presents with severe back pain &
bilateral leg weakness for 3 days. He claims to bilateral leg weakness for 3 days. He claims to
experience electrical tingling sensation down his spine experience electrical tingling sensation down his spine
prior to experiencing weakness of his lower extremities. prior to experiencing weakness of his lower extremities.
Recommended test during breast cancer What is the most probable diagnosis of this patient
surveillance/monitoring given the presentation?
a. Tumor marker CA 15-3 a. Hypokalemia
b. Bone scan b. Chronic fatigue syndrome
c. Mammogram c. Spinal cord compression
d. CT scan of chest & abdomen d. Cerebrovascular disease (stroke)
27. This the desired response to cancer treatment if 33. A 59 yo male presents with severe back pain &
the goal is TO CONTROL the disease: bilateral leg weakness for 3 days. He claims to
a. Stable response - to palliate experience electrical tingling sensation down his spine
b. Complete response - to cure prior to experiencing weakness of his lower extremities.
c. Partial response Best imaging modality to confirm the diagnosis?
d. Progressive disease a. Blood test including electrolytes
b. CT scan with contrast
28. Which is TRUE statement about tumor cell growth: c. Xray
a. The lag phase is the phase of cancer detection d. MRI
because of its explosive growth - Log phase
b. Tumor cell growth is linear - Gompertzian
c. Tumors in the plateau phase should undergo 34. Characteristic finding in SVC syndrome, EXCEPT:
tumor-debulking surgery before a. Dilated neck veins
chemotherapy can be effective b. Widened mediastinum
d. Very big necrotic tumors are mostly in the c. Pulsus paradoxus
logarithmic phase. - Plateau phase d. Facial edema
29. Which systemic chemotherapy is cytotoxic? 35. A 58 yo woman with stage III breast cancer was
a. Cisplatin given out patient systemic chemotherapy with
b. Interleukins docetaxel, doxorubicin and cyclophosphamide and was
c. Monoclonal Antibodies also given ondansetron. The next day she comes to see
d. Tamoxifen you because she had 2 episodes of blood in her urine.
You are suspecting hemorrhagic cystitis. Which among
30. A 58 yo man presented with anorexia, fatigue & the medication she received is the most likely culprit for
vague right sided abdominal discomfort for 2 months. the hemorrhagic cystitis
History revealed patient is a diabetic for 18 yrs & a. Doxorubicin
hypertensive for 10 yrs. His PE was unremarkable b. Ondansetron
except for mild pallor. Colonoscopy revealed a non c. Cyclophosphamide (Ifosfamide & acrolein)
obstructing transverse colon mass. Patient underwent d. Docetaxel
explore laparotomy & resection of circumferential
necrotic & fungating mass. Further work up revealed 36. A 59 yo male presents with severe back pain &
liver metastasis. Plan is to give systemic palliative bilateral leg weakness for 3 days. He claims to
chemotherapy. Which would be the recommended experience electrical tingling sensation down his spine
regimen base on this patient’s profile prior to experiencing weakness of his lower extremities.
a. FOLFIRI What is the most common malignancy associated with
b. FOLFOC this condition
c. Folinic acid + 5FU a. Lymphoma
d. Capecitabine b. Lung cancer
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40. Which is not a goal of treatment for 46. True of colorectal cancer, EXCEPT:
chemoradiation in esophageal cancer treatment? a. Left-sided tumors are annular in growth and
a. To eradicate occult micrometastatic disease therefore seldom cause obstruction
b. To increase the rate of complete resection b. Proximal colon cancers are more common
with negative circumferential margin c. Majority is adenocarcinoma
c. To downstage the disease d. Endoscopy with biopsy is the best method of
d. To lower the rate of distant metastases diagnosis
41. What is the best adjuvant treatment for a 47. What is the recommended adjuvant treatment for
premenopausal breast cancer patient who is Breast Cancer stage II, premenopausal, ER and PR
node-positive and ER-positive? negative HER2neu-negative?
a. Chemotherapy + hormonal therapy a. Chemotherapy with Herceptin
b. Radiation only b. Hormonal therapy only
c. Hormonal therapy only c. Chemotherapy and hormonal therapy
d. Chemotherapy only d. Chemotherapy only
42. A 60 yo man comes to your clinic with complaint of 48. Patient comes to you complaining of dysphagia
recurrent epigastric pain over a year this time with initially to solids then to liquids for 3 months now.
associated weight loss. What is the single best What will be the best method for diagnosis?
a. Upper GI endoscopy
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51. A 45 yo bank manager consults you for an 56. Which of the following has the highest risk for
incidental finding of a solitary liver nodule about 1.2cm Tumor Lysis Syndrome?
by ultrasound. He is anxious that it is malignant. He is a. Breast cancer with elevated creatinine and
asymptomatic and has unremarkable physical uric acid and normal LDH
examination findings. How will you best work-up this b. Acute leukemia with elevated LDH, normal
patient? creatinine, and uric acid
a. Request for HBsAg and Anti HCV, serum AFP c. Small cell lung cancer with elevated creatinine,
and core needle biopsy uric acid and LDH
b. Request for HBsAg and Anti-HCV, tri-phasic d. Lymphoma with normal creatinine, uric acid
CTscan, and core needle biopsy and LDH
c. Request for HBsAg and Anti-HCV and
multi-phasic CT scan then core-needle biopsy 57. G for cell cycle
only if necessary a. Gap
d. Request for HbsAg and anti-HCV and initial b. Genesis
serum AFP then repeat serum AFP and c. Gompertzian
ultrasound every 3 month d. Growth
52. The following indicate poor prognosis in lung Ca, 58. Level of clinical detection
a.
Except: 105
b.
a. Generalized weakness & fatigue 109
b. Large cell histology c. 1012
d.
c. Female sex 1014
d. Weight loss >10% in 6 months
53. True about the management of non-small cell Ca 59. Malignancy that is mesenchymal in origin
(NSCLC), EXCEPT: a. Carcinoma
a. Best supportive care is an option for b. Sarcoma
advanced & metastatic disease c. Leukemia
b. Radiation is an alternative for medically unfit d. Lymphoma
patients
c. Sequential chemo-radiation increases toxicity 60. Best diagnostic procedure for diagnosing breast
but has better local control compared to cancer:
concurrent chemo-radiation a. Core Needle Biopsy
d. Surgical resection remains the treatment of b. Excision Biopsy
choice if cure is the goal. c. Fine Needle Biopsy
d. Incisional biopsy
54. A 60 yo male with hepatitis C is diagnoses with HCC
stage 1 Child’s Pugh B. Work ups revealed no
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a. Irinotecan
61. The most common cancer that cause Death in b. Oxaliplatin
Females.
a. Breast 71. Side effect of oxaliplatin
b. Lungs a. -
c. Ovarian b. Hypertension
d. Liver c. Neuropathy
d. Neutropenia
62. Most common site of spinal cord compression:
a. Cervical 72. True of esophageal CA?
b. Thoracic a. Onset after 60 years old
c. Lumbar b. Common in High Socioeconomic Status
d. Sacral c. More common in Female
d. Uncommon but Lethal
63. Has propensity for bilaterality
a. Invasive Ductal CA 73. Most common site of esophageal cancer
b. Invasive Lobular Ca - Lower third
c. Ductal CA in situ
d. Lobular CA in situ 74. Most common hematologic spread of gastric cancer
a. Bones
64. Classification of doxorubicin b. Brain
- Topoisomerase Inhibitor c. Lungs
d. Liver
65. Breast cancer with best prognosis
a. ER/PR (+) 75. Standard Treatment for Stage 1 gastric cancer
b. ER/PR (-) a. Total gastrectomy with lymph node resection
c. HER2 (-) b. Subtotal gastrectomy with lymph node
d. Triple negative resection
c. Near total gastrectomy
66. Most common presentation in male breast cancer d. Subtotal gastrectomy only (**Ba’t kailangan
a. Nipple discharge ng Lymph Node Resection sa Stage 1?)
b. Peau d’orange
c. Unilateral gynecomastia 76. Most common presenting symptom of Pancreatic
d. Ulceration CA
- Abdominal Pain
67. Most common in lung cancer
a. Cough 77. Which of the following is a serum tumor marker for
b. Chest pain HCC?
c. Dyspnea a. AFP
d. Weight Loss b. CA 19-9
c. CEA
68. Treatment for stage 1 non small cell lung cancer d. 15-3
a. Surgery
b. Chemo RT 78. Treatment of choice stage IV HCC?
c. RT Sorafenib
d. TKI
79. High fat, low calcium and fiber. High risk for the ff
69. Premalignant polyp with high risk for colon ca cancer except
a. Pedunculated a. Pancreas
b. 2 cm polyp b. Colorectal
c. Tubulovillous c. Breast
d. Sessile d. Liver
70. Cornerstone Treatment for Colon CA: 80. Not a warning sign of malignancy
a. 5-FU a. Spotting in postmenopausal
b. Folinic Acid b. Nagging cough in smoker
ONCOLOGY SAMPLEX
November 2020
85. All are systemic cancer therapy, EXCEPT 93. Complaining initially dysphagia to solids then to
a. Cytotoxic liquids 3 months now. Method of diagnosis?
b. Hormonal a. Abdominal ultrasound
c. Immunologic b. Upper GI endoscopy
d. Brachytherapy c. Chest x-ray
d. Abdominal CT scan
86. Decrease in size of the tumor in two diameters by
25% 94. Poor prognosis in Non-Small Cell Lung CA
a. Partial (**Decrease in size po yun tanong) Answer: Large Cell Lung CA
b. Progressive
c. Stable 95. In what type of cancer would you recommend
d. Complete chemotherapy with or without RT if the patient has
good survival status?
87. The following indicate poor prognosis in Lung a. Stage 4 lung cancer
Cancer except: b. Stage 3 unresectable liver cancer
a. Weight Loss >10% in 6 mos c. Extensive SCLC
b. Generalized weakness and fatigue d. Locally advanced pancreatic cancer
c. Large cell history
d. Female sex 96. criteria for diagnosing colorectal cancer except
a. CRC involving 2 successive generations
88. Management of NSCLC except b. one first degree relative
a. RT is an alternative Tx for medically unfit c. earliest age to diagnose is 60
patients d. all are the criteria for crc
b. Surgery is the curative goal
c. Sequential chemo-RT is more toxic but gives 97. Risk factor for esophageal Ca, except
better control than concurrent chemo-RT a. Tylosis
d. io da! b. GERD
c. Strictures from caustic injury
89. True of Small cell lung CA d. Menetrier’s disease
a. Less aggressive than non small cell
ONCOLOGY SAMPLEX
November 2020