Ñ- Hetero

polymer handed
of aminohelices
acids
structure only right are ✓
(5)
observed Myoglobin
(
Chain
I
.

n.te-m.nu/peph--debonds
c- terminal

MHz ←
/ N C
muscle
pigment
terminal terminal
free 153 d-As single
. .

polypeptide
Fibroin

*
keratin threads

( night
helix
( p pleated
-

sheet) 3zqBBBg

p-glo← → ✗ -

globulin
•
•

Fetz (Ferrous )
-
•

globin ( Anychain)
146
p
- -

essential
I
,
/ -
14°)
Adult Hb)
for biological gap , (
activity of proteins 4- globin
d t
✗ay ( fetal Hb )
enzymes /
141 AA chain ,
Note : Amino acids amino acids
are
g-
-

14%-2%2 -

S -

CH }

HII -
C- COOH →
functional
I
H
z
group .

Methionine
C N

H -
bonds

( }
o

* .

N c

N
} Antiparallel
C
 -
¢43 ) -
aliphatic
side
chain
(
Hydrophobic )
¥iÉ→M ,
AA

{ }
" •
I. a-
-

↳
or

electrostatic
attraction

84
✓

C
,
✓
C
•

N
te
PROTEIN STRUCTURE

9-

9- Keratin

→
disulphide
bonds

enzymes Ithyoglobiu
most
 a.) which of the
is
(matrix
following
) Insulin

Amylase , pepsin dependent ?

A) GLUT I
Glucagon
-

>

b) 2
( birds to
antigen)
-
n

✓
c.) n -

3
Toncha morels etc
,
- -

#dr " -

4
NEET-2019 _
( Glucose
Transporter 4) -

Most abundant protein of biosphere → RUBISCO

Cellulose
"
"

carbohydrate n →

NEET
2020
[second most abundant
protein i. → Collagen
Chiba
( carbohydrate
" →
" "

most abundant
protein in animal world →
Collagen
Ribosome RNA protein + prosthetic metal ions
,
coenzymes
groups
__

Ptoteins ( vitamin)

)
(non-protein
part)
=
proteins

•
--
Hsin
O Carbo
peptones
8m¥
+
P'
-

hydrate proteose
_Ls&carb•✗y peptidase + zntz

F-b-uhogeu-sf.is#---t----%EEo
B@o⑧mE _~ BF⑤ globule
fibrous
☒
Periphery
_ Blood
•②
Polypeptide
chain

Hydrophobic core
 Blood 7- oy
pH
=

Denaturation Proteins Breakdown

of :
of bonds which
-

unfolds the protein

resulting in loss
of biological
activity
2° ,
30,4° structure - denatured
1° , ,
- intact

Denaturing agents
geeaoymdal
's
0
's

Radiations ;i binds
a) Physical
→

X-rays Y rays ,
-

to
protein
coagulation
← Heat
stegrps
quiff
Acids alkali ,

b) Chemical
- , ,

U⑨ salicylic acidmetals

Fl
1
,

2-
mercapto ethanol Heavy ;

iueuum.su?f-s-Ii-sw--sr&TFEonbyYEo
- viruses ,
bacteria

fungi C pathogens>
.

phobic
Devaluing
•

Denaturation usually is

Renata ration is
possible in
also some cases
shown
upon
experimentally
of Denaturing agents (
removal
Ainisen
by
?⃝
 Haemoglobin ¥ >
Denatured Hb

( Deke Removal
of
1 salicylic
'

ng acid
agent) →

Renate red Hb

( Normal form)
* Denaturation causes TÉ% of
medium .

had
guarantees
protein solubility t
,

ÉB•
-

sushant
if
→
 Caused
"

by
"

Kushtrog leprosy
= -

Mycobacterium leprae ) "

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calm
LIPIDS.ES#fattyacidslalcohol--
1 classification animal
=

( cellmembstabilieg
.

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steroid

produced
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.

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t→
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-

←
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Cholesterol
( Tui
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If
6

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dot
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phosphi de
propane

membrane CHB
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"
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-

Len ,
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I
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acids Tripalmitin / Triglyceride with

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purefal Palmitic
↳
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-

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acid)

Ho -

ÉÑ¥¥ÉpÉ•cnz
 0

É
HE
1
-
OH HO - -

Rs
HI -0 - É -

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,
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I
-

I
→ HC -
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-
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OH 1
HE
-

OH
HE
-

Monoglyeeri.de/MonoacylR-d'-f0H
°

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I
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HE -0 -
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R,
,

He
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or

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-

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< 1
OH HO É Rz
Diacyl
glycerol
+
-

HE
-

É
- -

HE
-
O - -

Rz
Triglyceride / Triacylglycaol .
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~
1)
fatty
Acids ¥-5bn

H
H

a-
Fairland "

H H

"
H L I H

i±d
,

unsaturated H
Pullfats - Similar
-
Fatty acids H

Raised fats -

different
" '
,

oils
liquid at temperature
-

room

Hard solid
fats -
at " "

vegetable Iteration vegetable gheeldalda)

oil
( unsaturated ) (saturated )
 FA Unsaturated FA
"#
t ↳h" d
"

Palmatoleic acid

|
"
p
"

→
12 p -

q
-

M →
Myristicaceae 14 I -0 -
Oleic acid

P Palmitic acid 16 2 L Linoleic acid 18

✓
-
→

S stearic acid 18 t
Linolenic acid
I 3
→

Arachidonic
.

A→ acid ] 20

✓ A
- Arachidicau.dz , 4
Unsaturation
Degree of
-

=NÑde
[Acetyl Jze
bonds
Acetic acid →

Cont
CHZCOOH
.

Acetyl 2C 2C 2C 2C 2C
-
- - -

f-

coenzyme
atyaid .
 /
Fish oil Cod liver oil
* 3- EÉd ←

[[
Linolenic acid Sheik liver oil)
eg
DHA Docosahexaenoic acid end
One-off
-

EIA Eicosapentaenoic
2
6 z
-

acid 3
5

t
y

cardiovascular
good for nervous &

4 dys)lhr- 3

y
3 1

i '

Omega -
6
FAY Arachidonic
acid
•
s

Linoleic acid

Omega ↳
-

9 FA

/ oleic acid
double bond at 9th Carbon

from Omega end .

 Esters with other / complex
a.) Waxes : -

of fatty acid
alcohol
Candle
Paraffin -

Animal
wax . I Used as
suppositories
d
]
rectal or Paraffin
Lanolin →
fat drugs given via vaginalroute
produced bacteria ( Mycobacterium
Wax D →

by Leprosy
-

_>÷wg leprae )
"

Beeswax
cerumen provides pathogenicity > to

tewax (ceruminous glands)

bacteria drug
suberin

;÷}
→ Cas parian
.

Culture

of
hydrophytes xerophytes
a.

1
=

waxes
plant